Development of Lifting and Lowering-in Plan for the Control of Construction Stresses

2020 ◽  
Author(s):  
Jiawei Wang ◽  
Yong-Yi Wang ◽  
William A. Bruce ◽  
Steve Rapp ◽  
Russell Scoles
Keyword(s):  
Stress Analysis ◽  
Analysis Tool ◽  
Graphical Interface ◽  
Height Range ◽  
The Core ◽  
Extensive Analysis ◽  
Concrete Coating ◽  
Cross Country ◽  
Girth Welds ◽  
Core Functionality

Abstract Construction of a cross-country pipeline involves lifting the pipeline off the skids and lowering it into the trench (lifting and lowering-in). This can introduce the highest stress magnitude that the pipe may experience over its service life. If not managed properly, overly high stresses may cause integrity issues during construction and/or service. If the girth welds are qualified and accepted using alternative flaw acceptance criteria, such as those in API 1104 Annex A and CSA Z662 Annex K, these stresses must be kept below a preset level during lifting and lowering-in to satisfy the requirements of those standards. This paper covers the development and usage of a stress analysis tool for the continuous lifting and lowering-in of pipe strings without a concrete coating or river weights. The outcome of the stress analysis can be used to develop lifting and lowering-in plans for construction crews. The core functionality of the application tool is to calculate the stresses from bending in the vertical and horizontal planes. The stresses from vertical bending are derived from an extensive analysis of continuous lifting and lowering-in processes. The stresses from horizontal bending are calculated using closed-form analytical solutions. The tool provides a graphical interface that interprets the background stress analysis results and displays information necessary for the development of lifting and lowering-in plans. The tool can be used to evaluate what-if scenarios for various tentative lifting and lowering-in scenarios. The process of using the tool to develop lifting and lowering-in plans is demonstrated in this paper through an example problem. The number of sidebooms and other lifting and lowering-in parameters such as sideboom spacing and lifting height range are changed to make the lifting and lowering-in plan easy to use for the laying contractors. Such tradeoffs can be addressed proactively with construction contractors to ensure that a mutually acceptable approach to lifting and lowering-in is taken.

Identification of CCNB2 expression in triple-negative breast cancer based on bioinformatics results

2021 ◽  
Author(s):  
jintao cao ◽  
SHUAI SUN ◽  
RAN LI ◽  
RUI MIN ◽  
XINGYU FAN ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Triple Negative Breast Cancer ◽  
Protein Complex ◽  
Triple Negative ◽  
Expression Profiles ◽  
Pathway Enrichment Analysis ◽  
Analysis Tool ◽  
The Core ◽  
Core Genes

Abstract Background The current epidemiology shows that the incidence of breast cancer is increasing year by year and tends to be younger. Triple-negative breast cancer is the most malignant of breast cancer subtypes. The application of bioinformatics in tumor research is becoming more and more extensive. This study provided research ideas and basis for exploring the potential targets of gene therapy for triple-negative breast cancer (TNBC). Methods We analyzed three gene expression profiles (GSE64790、GSE62931、GSE38959) selected from the Gene Expression Omnibus (GEO) database. The GEO2R online analysis tool was used to screen for differentially expressed genes (DEGs) between TNBC and normal tissues. Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were applied to identify the pathways and functional annotation of DEGs. Protein–protein interaction network of these DEGs were visualized by the Metascape gene-list analysis tool so that we could find the protein complex containing the core genes. Subsequently, we investigated the transcriptional data of the core genes in patients with breast cancer from the Oncomine database. Moreover, the online Kaplan–Meier plotter survival analysis tool was used to evaluate the prognostic value of core genes expression in TNBC patients. Finally, immunohistochemistry (IHC) was used to evaluated the expression level and subcellular localization of CCNB2 on TNBC tissues. Results A total of 66 DEGs were identified, including 33 up-regulated genes and 33 down-regulated genes. Among them, a potential protein complex containing five core genes was screened out. The high expression of these core genes was correlated to the poor prognosis of patients suffering breast cancer, especially the overexpression of CCNB2. CCNB2 protein positively expressed in the cytoplasm, and its expression in triple-negative breast cancer tissues was significantly higher than that in adjacent tissues. Conclusions CCNB2 may play a crucial role in the development of TNBC and has the potential as a prognostic biomarker of TNBC.

scholarly journals HIPSTER

2019 ◽  
Vol 214 ◽  
pp. 06027
Author(s):  
Adrian Bevan ◽  
Thomas Charman ◽  
Jonathan Hays
Keyword(s):  
Neural Networks ◽  
High Energy Physics ◽  
High Energy ◽  
Event Recognition ◽  
The Core ◽  
Rich Information ◽  
The Rich ◽  
Core Functionality ◽  
Python Package ◽  
Energy Physics

HIPSTER (Heavily Ionising Particle Standard Toolkit for Event Recognition) is an open source Python package designed to facilitate the use of TensorFlow in a high energy physics analysis context. The core functionality of the software is presented, with images from the MoEDAL experiment Nuclear Track Detectors (NTDs) serving as an example dataset. Convolutional neural networks are selected as the classification algorithm for this dataset and the process of training a variety of models with different hyper-parameters is detailed. Next the results are shown for the MoEDAL problem demonstrating the rich information output by HIPSTER that enables the user to probe the performance of their model in detail.

Perceived Level of Benefits and Risk Core Functionalities of an EHR System

2011 ◽  
pp. 297-312 ◽  
Author(s):  
Diane C. Davis ◽  
Minal Thakkar
Keyword(s):  
Significant Relationship ◽  
Institute Of Medicine ◽  
The Core ◽  
System A ◽  
The Status ◽  
Research Questions ◽  
Results Management ◽  
Core Functionality ◽  
Benefit And Risk

The need to adopt an electronic health record (EHR) system in United States (U.S.) hospitals seems to be more and more obvious when evaluating the benefits of improved patient safety, quality of care, and efficiency. The purpose of the study was to identify the status of EHR systems in U.S. hospitals in regard to the core functionalities implemented (as identified by the Institute of Medicine) and to determine if there was a significant relationship between perceived level of benefit and risk with the use of each core functionality, as well as if there was a significant relationship between the status of the EHR system and size of hospital. A national survey of U.S. hospitals was conducted to answer the research questions. The results showed that 37% had some components in all.of the core functionalities of an EHR system, while 27% were using at least some functionalities. Health information and data, administrative processes, and results management were the three core functionalities that a majority of hospitals had as a part of their EHR system. A significant positive correlation between perceived benefits and risks was found in all of the eight core functionalities. There was no significant relationship found between status of EHR system and size of hospitals.

Comparison of Thermal and Stress Analysis Results for a High Voltage Module Using FEA and a Quick Parametric Analysis Tool

2018 ◽  
Author(s):  
L. M. Boteler ◽  
S. M. Miner
Keyword(s):  
Stress Analysis ◽  
High Voltage ◽  
Parametric Analysis ◽  
Thermal Stresses ◽  
Analysis Tool ◽  
Element Analysis ◽  
Module Design ◽  
Fast Running ◽  
Packaging Structure ◽  
Low Order

A low order fast running parametric analysis tool, ParaPower, was used to arrive at the design for a novel high voltage module. The low order model used a 3D nodal network to calculate device temperatures and thermal stresses. The model assumed heat flux generated near the top surface of each device which is then conducted through the packaging structure and removed by convection. The temperature distribution is used to calculate thermal stresses throughout the package. This co-design modeling tool, developed for rectilinear geometries, allowed a rapid evaluation of the package temperatures and CTE induced stresses throughout the design space. However, once the final design configuration was determined a detailed finite element analysis was performed to validate the design. This paper compares the results obtained using ParaPower to the FEA, demonstrating the usefulness of the parametric analysis tool. Results for both temperature and CTE induced stress are compared. Two different stress models are evaluated. One based on the more traditional planar module design, which assumes a substantial substrate or heat spreader on which the module is assembled. The other model is less restrictive, eliminating the requirement for a substrate. The FEA modeling was performed using SolidWorks beginning with a thermal analysis followed by a stress analysis based on the temperature solution. Both the values and the trends of the temperatures and stresses were evaluated. The temperature results agreed to within 3.2°C. The trends and sign of the stresses were correctly predicted, but the magnitudes were not. One of the significant advantages of ParaPower is the speed of the computation. The run time for the parametric analysis was roughly two orders of magnitude faster than the FEA. This made it possible to build the model and complete the parametric analysis of roughly 500 runs in less than a day.

scholarly journals Automatic Curve Extraction for Digitizing Rainfall Strip Charts

2011 ◽  
Vol 28 (7) ◽  
pp. 891-906 ◽  
Author(s):  
H. E. van Piggelen ◽  
T. Brandsma ◽  
H. Manders ◽  
J. F. Lichtenauer
Keyword(s):  
Time Series ◽  
Batch Process ◽  
Rainfall Time Series ◽  
Graphical Interface ◽  
The Core ◽  
Cumulative Rainfall ◽  
Color Detection ◽  
Meta Information

Abstract A method has been developed that largely automates the labor-intensive extraction work for large amounts of rainfall strip charts and paper rolls. The method consists of the following five basic steps: 1) scanning the charts and rolls to high-resolution digital images, 2) manually and visually registering relevant meta information from charts and rolls and preprocessing rolls to locate day transitions, 3) applying automatic curve extraction software in a batch process to determine the coordinates of cumulative rainfall lines on the images, 4) postprocessing the curves that were not correctly determined in step 3, and 5) aggregating the cumulative rainfall in pixel coordinates to the desired time resolution. The core of the method is in step 3. Here a color detection procedure is introduced that automatically separates the background of the charts and rolls from the grid and subsequently the rainfall curve. The rainfall curve is detected by minimization of a cost function. In total, 321 station years of locations in the Netherlands have successfully been digitized and transformed to long-term rainfall time series with 5-min resolution. In about 30% of the cases, semiautomatic postprocessing of the results was needed using a purpose-built graphical interface application. This percentage, however, strongly depends on the quality of the recorded curves and the charts and rolls. Although developed for rainfall, the method can be applied to other elements as well.

Dynamic stress analysis of rotating twisted and tapered blades

1980 ◽  
Vol 15 (3) ◽  
pp. 117-126 ◽  
Author(s):  
V Ramamurti ◽  
S Sreenivasamurthy
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Stress Analysis ◽  
Dynamic Stress ◽  
Three Dimensional ◽  
The Finite Element Method ◽  
Extensive Analysis ◽  
Dynamic Stress Analysis ◽  
Skew Angles ◽  
Good Agreement

In this paper the finite element method has been used to determine the stresses and deformations of pre-twisted and tapered blades. Three-dimensional, twenty-noded isoparametric elements have been used for the analysis. Extensive analysis has been done for various pre-twist angles, skew angles, breadth to length ratios, and breadth to thickness ratios of the blades. Experiments were carried out to determine the stresses for the verification of the numerical results and they were found to be in good agreement.

Organisational Analysis

2017 ◽  
pp. 17-37
Keyword(s):  
Risk Assessment ◽  
Value Chain ◽  
The Other ◽  
Analysis Tool ◽  
Key Factors ◽  
Strategic Development ◽  
Business Architecture ◽  
Value Stream ◽  
The Core ◽  
Communication Facility

The organisational analysis described here (aimed at developing the plans for strategic development and risk assessment) is to determine the core functioning of the organisation. It is essential to get a clear unambiguous understanding of the key factors that drive the performance of the organisation and to determine what risks may threaten the organisation. To do this an organisation must carefully choose the analysis tools they will use to gather information about their organisation. Companies, while researching and analysing their business architecture, are rediscovering Michael Porter's value chain (Whittle, 2016). To understand the value creation aspect of the organisation, it is necessary to determine the critically significant value activities, together with any causal relations that are evident and where possible the degree of that relation. There is a suggestion that the value stream is a more basic analysis unit than the value chain and that the value chain can comprise several value stream components. The value stream may, therefore, be a better analysis unit to use when developing the value architecture. The business model cannot be called an analysis tool; however, it is a critical review tool for the other analysis activities and an essential communication facility for the organisation.

New technological revolution: Challenges and opportunities for Russia

2018 ◽  
pp. 5-25 ◽  
Author(s):  
G. I. Idrisov ◽  
V. N. Knyaginin ◽  
A. L. Kudrin ◽  
E. S. Rozhkova
Keyword(s):  
Industrial Revolution ◽  
Research Report ◽  
Technological Transformation ◽  
Strategic Research ◽  
Technological Revolution ◽  
The Core ◽  
Challenges And Opportunities ◽  
Country Analysis ◽  
Technological Transition ◽  
Cross Country

The article discusses the core changes, called the “new industrial revolution”. It addresses the challenges that Russia faces in its technological transition. Based on the cross-country analysis of the readiness to transition, we bring the target vision of the technological revolution for Russia. Risks and action scenarios are also evaluated, the main measures are proposed and the stages of their implementation are indicated. The aim of the article is to put the accelerated technological transformation in the list of priority goals for Russian economic policy. The article is based on the Center for Strategic Research report.

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