Effect of Process Parameters on Cellulose Fiber Alignment in Bio-Printing

2019 ◽  
Author(s):  
Md. Ahasan Habib ◽  
Bashir Khoda
Keyword(s):  
Process Parameters ◽  
Applied Pressure ◽  
Three Dimensional ◽  
Cellulose Fiber ◽  
Fiber Content ◽  
Direct Writing ◽  
Diverse Range ◽  
Printing Process ◽  
Nano Fiber ◽  
Deposition Direction

Abstract Three dimensional (3D) bio-printing or direct writing technique has become a popular tool in tissue engineering applications that uses a computer-controlled process to deposit bio-ink for reproducing 3D tissue. Among multiple bio-printing modal, extrusion-based printing is capable of depositing diverse range of hydrogel materials and their compositions as bio-ink. Both acellular bio-ink and cell-laden bio-ink can be extruded by controlling the writing parameters to achieve high (>80%) cell survivability and density along with spatial precision and accuracy in 3D space. To increase cell viability and improve mechanical properties, nano-materials are often added in the bio-ink. However, the interplay between 3D bio-printing process parameters, solid fiber content and deposited fiber orientation has not been investigated yet. A novel cellulose based nano-fiber filled bio-ink (i.e. TEMPO nano fibrillated cellulose fiber) is developed and used in this research. The distribution of fiber is explored with respect to the 3D bio-printing process parameters such as nozzle diameter, applied pressure, fiber content and, alginate content. We found, fiber alignments has a very strong correlation with the deposition direction and about 70% fiber falls within 20 degree of the deposition direction.

Influence of process parameters on the characteristics of electrohydrodynamic-printed UV-curing conductive lines on the fabric

2022 ◽  
Author(s):  
Wenjing Guo ◽  
Hu Jiyong ◽  
Xiong Yan
Keyword(s):  
Electrical Property ◽  
Line Width ◽  
Process Parameters ◽  
Flow Rate ◽  
Applied Voltage ◽  
Electrical Resistance ◽  
Uv Curing ◽  
Electrical Performance ◽  
Direct Writing ◽  
Printing Process

Abstract As a similar technology to the near-field static electrospinning, the emerging electrohydrodynamic (EHD) printing technology with digital printing process and compatibility of viscous particle-blended inks is one of the simplest methods of fabricating multifunctional electronic textiles.With increasing demands for textile-based conductive lines with controllable width and excellent electrical performance, it’s of great importance to know the influence of key process parameters on the morphology and electrical properties of EHD-printed UV-curing conductive lines on the fabric. This work will systematically explore the effect of the EHD printing process parameters (i.e. applied voltage, direct-writing height, flow rate and moving velocity of the substrate) on the morphology and electrical performance of the EHD-printed textile-based conductive lines, especially focus on the diffusion and penetration of inks on the rough and porous fabric. The UV-curing nano-silver ink with low temperature and fast curing features was selected, and the line width and electrical resistance of printed lines under different process parameters were observed and measured. The results showed that, unlike previous results about EHD printing on smooth and impermeable substrates, the ink diffusion related to fabric textures had a greater effect on the fabric-based conductive line width than the applied voltage and direct-writing height in the case of a stable jet. Meanwhile, the relationship between the line width and the flow rate met the equation of = 407.28 ∗ 1⁄2 , and the minimum volume on fabric per millimeter was 0.67μL to form continuous line with low electrical resistance. Additionally, the higher substrate moving velocity resulted in a smaller line width, while it deteriorated the thickness uniformity and electrical property of printed lines. Generally, due to the effect of surface structure of the fabric on the spreading and penetrating behavior of inks, the flow rate and the substrate moving velocity are two significant parameters ensuring the electrical property of printed lines. It is believed that these findings will provide some guides for applying electrohydrodynamic printing technology into flexible electronics on the woven fabric.

NUMERICAL SIMULATION OF PRESSURE-INDUCED CELL PRINTING

2015 ◽  
Vol 15 (05) ◽  
pp. 1550065 ◽  
Author(s):  
HASSAN ABEDINI ◽  
SAEID MOVAHED ◽  
NABIOLLAH ABOLFATHI
Keyword(s):  
Cell Viability ◽  
Biomedical Applications ◽  
Applied Pressure ◽  
Three Dimensional ◽  
Live Cells ◽  
Printing Process ◽  
Cell Printing ◽  
And Performance ◽  
Printing Processes ◽  
Applied Stresses

Nowadays, because of great biomedical applications of state-of-the art prototyping (bio-printing), many studies have been conducted in this field with focus on three-dimensional prototyping. There are several mechanisms for bio-printing of live cells such as piezoelectric and thermal and pneumatic inkjeting systems. Cell viability should be preserved during the bio-printing process. Lots of researches have been carried out to investigate and compare cell viability through different prototyping mechanisms. In order to quantify percentage of the cells that are killed during the proto-typing process, applied stresses on the cell and consequently its deformation should be calculated. A maximum strain energy density that the cell can tolerate is reported in the range of 25 Kj ⋅ m-3 to 100 Kj ⋅ m-3. This can be considered as a criteria to find the percentage of the damaged cells during the bio-printing processes. In this study, the bio-printing of the cell has been modeled and the cell viability have been investigated. Firstly, it is shown that in modeling of the bio-printing process, the effects of dynamic flow on calculating the applied stress on the cell is not negligible and must be considered. In the next step, the percentage of damaged endothelial cell aggregate under 80 kPa applied pressure (64 MPa/m) and 200 micron nozzle diameter is reported. Based on findings of this study, the percentage of endothelial cells viability under mentioned condition is reported 76%. The proposed method of this study can be utilized to examine the cell viability and performance of each prototyping systems.

Melt Electrohydrodynamic Direct-Writing Micro/Nano Fiber with Restriction of Heated Sheath Gas

2015 ◽  
Vol 645-646 ◽  
pp. 45-51 ◽  
Author(s):  
Zhao Jie Yu ◽  
Lin Jie Wang ◽  
Ling Ling Sun ◽  
Yi Hong Lin ◽  
Wei Wang ◽  
...  
Keyword(s):  
Surface Morphology ◽  
Process Parameters ◽  
Feed Rate ◽  
Direct Write ◽  
Direct Writing ◽  
Nanostructure Fabrication ◽  
Novel Technology ◽  
Melt Electrospinning ◽  
Nano Fiber ◽  
Excellent Method

Melt electrospinning is a novel technology in the field of 1D micro/nanostructure fabrication. Decreasing the diameter and promoting surface morphology of melt fiber are the key for the application of melt electrospinning technology. Heated sheath gas is introduced to build up melt electrospinning direct-write technology, and then orderly micro/nanofibers can be direct-written. The heated sheath gas provided a good way to increase the temperature of melt jet, by which solidification can be slowed. With the help of heated sheath gas, the diameter of melt fiber can be decreased. The affects of process parameters on the diameter of melt electrospinning fiber was investigated, the diameter of melt electrospinning fiber increased with the increasing of temperature of spinneret and feed rate, but decreased with the increasing of voltage and distance between spinneret and collector. Heated sheath gas is an excellent method to promote the application of melt electrospinning.

scholarly journals Advanced Micro-Actuator/Robot Fabrication Using Ultrafast Laser Direct Writing and Its Remote Control

2020 ◽  
Vol 10 (23) ◽  
pp. 8563
Author(s):  
Sangmo Koo
Keyword(s):  
Three Dimensional ◽  
Processing Technique ◽  
Direct Writing ◽  
Laser Direct Writing ◽  
Precise Control ◽  
Two Photon ◽  
Non Invasive ◽  
Acoustic Control ◽  
Fs Laser ◽  
Invasive Control

Two-photon polymerization (TPP) based on the femtosecond laser (fs laser) direct writing technique in the realization of high-resolution three-dimensional (3D) shapes is spotlighted as a unique and promising processing technique. It is also interesting that TPP can be applied to various applications in not only optics, chemistry, physics, biomedical engineering, and microfluidics but also micro-robotics systems. Effort has been made to design innovative microscale actuators, and research on how to remotely manipulate actuators is also constantly being conducted. Various manipulation methods have been devised including the magnetic, optical, and acoustic control of microscale actuators, demonstrating the great potential for non-contact and non-invasive control. However, research related to the precise control of microscale actuators is still in the early stages, and in-depth research is needed for the efficient control and diversification of a range of applications. In the future, the combination of the fs laser-based fabrication technique for the precise fabrication of microscale actuators/robots and their manipulation can be established as a next-generation processing method by presenting the possibility of applications to various areas.

Optical tuning of three-dimensional photonic crystals fabricated by femtosecond direct writing

2005 ◽  
Vol 87 (9) ◽  
pp. 091117 ◽  
Author(s):  
Dennis McPhail ◽  
Martin Straub ◽  
Min Gu
Keyword(s):  
Photonic Crystals ◽  
Three Dimensional ◽  
Direct Writing

Investigations of process parameters during dissolution studies of drug loaded 3D printed tablets

2021 ◽  
pp. 095441192199358
Author(s):  
Varun Sharma ◽  
Khaja Moinuddin Shaik ◽  
Archita Choudhury ◽  
Pramod Kumar ◽  
Prateek Kala ◽  
...  
Keyword(s):  
Dissolution Rate ◽  
Process Parameters ◽  
Empirical Relation ◽  
Three Dimensional ◽  
Critical Parameters ◽  
Fused Deposition Modelling ◽  
Fused Deposition ◽  
Rate Of Dissolution ◽  
3D Printed ◽  
Percentage Release

The present research paper attempts to study the effect of different process parameters on the dissolution rate during 3D printed tablets. Three-dimensional printing has the potential of serving tailored made tablets to cater personalized drug delivery systems. Fluorescein loaded PVA filaments through impregnation route was used to fabricate tablets based on Taguchi based design of experimentation using Fused Deposition Modelling (FDM). The effect of print speed, infill percentage and layer thickness were analyzed to study the effect on rate of dissolution. Infill percentage followed by print speed were found to be critical parameters affecting dissolution rate. The data analysis provided an insight into the study of interaction among different 3D printing parameters to develop an empirical relation for percentage release of the drug in human body.

A hybrid multi-objective optimization of 3D printing process parameters using genetic algorithm

2021 ◽  
Author(s):  
Zahoor Ahmed Shariff ◽  
Lokesh M. ◽  
K. Mayandi ◽  
A. K. Saravanan ◽  
P. Sethu Ramalingam ◽  
...  
Keyword(s):  
Genetic Algorithm ◽  
3D Printing ◽  
Process Parameters ◽  
Multi Objective Optimization ◽  
Printing Process ◽  
Multi Objective
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