CYP1A2 Genotype Polymorphism Influences the Effect of Caffeine on Anaerobic Performance in Trained Males

2021 ◽  
pp. 1-6
Author(s):  
Shahin Minaei ◽  
Morteza Jourkesh ◽  
Richard B. Kreider ◽  
Scott C. Forbes ◽  
Tacito P. Souza-Junior ◽  
...  
Keyword(s):  
Body Mass ◽  
Power Output ◽  
Peak Power ◽  
Anaerobic Power ◽  
Random Order ◽  
Peak Power Output ◽  
Fatigue Index ◽  
Double Blind ◽  
Minimum Power ◽  
Output Only

The purpose was to investigate the effects of CYP1A2 −163C > A polymorphism on the effects of acute caffeine (CAF) supplementation on anaerobic power in trained males. Sixteen trained males (age: 21.6 ± 7.1 years; height: 179.7 ± 5.6 cm; body mass: 72.15 ± 6.8 kg) participated in a randomized, double-blind, placebo (PLA) controlled crossover design. Participants supplemented with CAF (6 mg/kg of body mass) and an isovolumetric PLA (maltodextrin) in random order and separated by 7 days, before an all-out 30-s anaerobic cycling test to determine peak, average, and minimum power output, and fatigue index. Genomic deoxyribonucleic acid was extracted to identify each participants CYP1A2 genotype. Six participants expressed AA homozygote and 10 expressed C alleles. There was a treatment by genotype interaction for peak power output (p = .041, η2 = .265, observed power = 0.552) with only those expressing AA genotype showing improvement following CAF supplementation compared with PLA (CAF: 693 ± 108 watts vs. PLA: 655 ± 97 watts; p = .039), while no difference between treatments was noted in those expressing C alleles (CAF: 614 ± 92 watts vs. PLA: 659 ± 144 watts; p = .135). There were no other interaction or main effects for average or minimum power output, or fatigue index (p > .05). In conclusion, the ingestion of 6 mg/kg of CAF improved peak power output only in participants with the AA genotype compared with PLA; however, expression of the CYP1A2 did not influence average or minimum power output or fatigue index.

Anaerobic Cycling Power Output with Variations in Recumbent Body Configuration

2001 ◽  
Vol 17 (3) ◽  
pp. 204-216 ◽  
Author(s):  
Raoul F. Reiser ◽  
Michael L. Peterson ◽  
Jeffrey P. Broker
Keyword(s):  
Lower Extremity ◽  
Body Mass ◽  
Power Output ◽  
Peak Power ◽  
High Performance ◽  
Anaerobic Power ◽  
Average Power ◽  
Knee Joints ◽  
Anaerobic Power Output ◽  
Human Powered

While the recumbent cycling position has become common for high-performance human-powered vehicles, questions still remain as to the influence of familiarity on recumbent cycling, the optimal riding position, and how recumbent cycling positions compare to the standard cycling position (SCP). Eight recumbent-familiar cyclists and 10 recreational control cyclists were compared using the 30-s Wingate test in 5 recumbent positions as well as the SCP. For the recumbent positions, hip position was maintained 15° below the bottom bracket while the backrest was altered to investigate body configuration angle (BCA: the angle between the bottom bracket, hip, and a marker at mid-torso) changes from 100° to 140° in 10° increments. Between-groups analysis found that only 4 of the 126 analyzed parameters differed significantly, with all trends in the same direction. Therefore both groups were combined for further analysis. Whole-group peak power (14.6 W/kg body mass) and average power (9.9 and 9.8 W/kg body mass, respectively) were greatest in the 130° and 140° BCA positions, with power dropping off as BCA decreased through 100° (peak = 12.4 W/kg body mass; avg. = 9.0 W/kg body mass). Power output in the SCP (peak = 14.6 W/kg body mass; avg. = 9.7 W/kg body mass) was similar to that produced in the 130° and 140° recumbent BCA. Average hip and ankle angles increased (became more extended/ plantar-flexed), 36° and 10°, respectively, with recumbent BCA, while knee angles remained constant. The lower extremity kinematics of the 130° and 140° BCA were most similar to those of the SCP. However, SCP hip and knee joints were slightly extended and the ankle joint was slightly plantar-flexed compared to these two recumbent positions, even though the BCA of the SCP was not significantly different. These findings suggest: (a) the amount of recumbent familiarity in this study did not produce changes in power output or kinematics; (b) BCA is a major determinant of power output; and (c) recumbent-position anaerobic power output matches that of the SCP when BCA is maintained, even though lower extremity kinematics may be altered.

scholarly journals Determining the Peak Power Output for Weightlifting Derivatives Using Body Mass Percentage: A Practical Approach

2021 ◽  
Vol 3 ◽  
Author(s):  
Marcel Lopes dos Santos ◽  
Adam Jagodinsky ◽  
Kristen M. Lagally ◽  
Valmor Tricoli ◽  
Ricardo Berton
Keyword(s):  
Body Mass ◽  
Power Output ◽  
Peak Power ◽  
Practical Approach ◽  
Peak Power Output ◽  
Mass Percentage

Effect of oral creatine supplementation on power output and fatigue during bicycle ergometry

1995 ◽  
Vol 78 (2) ◽  
pp. 670-673 ◽  
Author(s):  
W. H. Cooke ◽  
P. W. Grandjean ◽  
W. S. Barnes
Keyword(s):  
Power Output ◽  
High Intensity ◽  
Peak Power ◽  
Creatine Supplementation ◽  
Total Work ◽  
Fatigue Index ◽  
Bicycle Ergometry ◽  
Double Blind ◽  
Mean Values ◽  
Time To Peak

Our purpose was to determine the effect of oral creatine supplementation on exercise performance during high-intensity short-duration bicycle sprinting. Power output was recorded for 12 healthy untrained males (age 24.08 +/- 0.53 yr, weight 81.22 +/- 1.32 kg) before and after 5 days of creatine (n = 6) or placebo (n = 6) supplementation. A double-blind research design was employed. Subjects performed maximal sprints against a constant load (111.8 N) for 15 s. Each one-half pedal revolution was magnetically counted, and subsequent measurements of peak power, time to peak power, total work, and the fatigue index were digitized and stored on disk. Mean values for peak power, time to peak power, total work, and fatigue index were 958.01 +/- 40.66 W, 4.09 +/- 0.82 s, 11.28 +/- 0.46 kJ, and 32.1 +/- 1.58% decline from peak power, respectively. No significant differences were observed within or between groups before or after supplementation for any of the mechanical parameters measured (P > 0.05). These findings suggest that oral creatine supplementation does not positively affect power output or fatigue during continuous high-intensity bicycle exercise in untrained men.

The effect of load based on body mass percentage on peak power output in the hang power clean, hang high pull, and mid-thigh clean pull

2021 ◽  
Author(s):  
Marcel LOPES DOS SANTOS ◽  
Ricardo BERTON ◽  
Adam E. JAGODINSKY ◽  
Michael R. TORRY ◽  
Kristen M. LAGALLY
Keyword(s):  
Body Mass ◽  
Power Output ◽  
Peak Power ◽  
Peak Power Output ◽  
Mass Percentage ◽  
Power Clean

Power-Time, Force-Time, and Velocity-Time Curve Analysis during the Jump Squat: Impact of Load

2008 ◽  
Vol 24 (2) ◽  
pp. 112-120 ◽  
Author(s):  
Prue Cormie ◽  
Jeffrey M. McBride ◽  
Grant O. McCaulley
Keyword(s):  
Body Mass ◽  
Power Output ◽  
Peak Power ◽  
Peak Power Output ◽  
Power Development ◽  
Time Curve ◽  
Force Time ◽  
The Impact ◽  
External Loads ◽  
Male Subjects

The purpose of this investigation was to examine the impact of load on the power-, force- and velocity-time curves during the jump squat. The analysis of these curves for the entire movement at a sampling frequency of 200–500 Hz averaged across 18 untrained male subjects is the most novel aspect of this study. Jump squat performance was assessed in a randomized fashion across five different external loads: 0, 20, 40, 60, and 80 kg (equivalent to 0 ± 0, 18 ± 4, 37 ± 8, 55 ± 12, 74 ± 15% of 1RM, respectively). The 0-kg loading condition (i.e., body mass only) was the load that maximized peak power output, displaying a significantly (p≤ .05) greater value than the 40, 60, and 80 kg loads. The shape of the force-, power-, and velocity-time curves changed significantly as the load applied to the jump squat increased. There was a significantly greater rate of power development in the 0 kg load in comparison with all other loads examined. As the first comprehensive illustration of how the entire power-, force-, and velocity-time curves change across various loading conditions, this study provides extensive evidence that a load equaling an individuals body mass (i.e., external load = 0 kg) maximizes power output in untrained individuals during the jump squat.

Caffeine supplementation for 4-day, followed by acute ingestion, did not impact triathlete output power after submaximal intensity exercise

2019 ◽  
Vol 18 (3) ◽  
pp. 118
Author(s):  
Anderson Pontes Morales ◽  
Felipe Sampaio-Jorge ◽  
Thiago Barth ◽  
Alessandra Alegre De Matos ◽  
Luiz Felipe Da Cruz Rangel ◽  
...  
Keyword(s):  
Blood Lactate ◽  
Output Power ◽  
Body Mass ◽  
Effect Size ◽  
Power Output ◽  
Anaerobic Power ◽  
Lactate Concentration ◽  
Wingate Test ◽  
Large Effect Size ◽  
Acute Ingestion

Introduction: The aim of this study was to test the hypothesis that caffeine supplementation (6 mg·kg-1 body mass) for 4-days, followed by acute intake, would impact five male triathletes output power after performed submaximal intensity exercise. Methods: This was a randomized, double-blind, placebo-controlled crossover study, placebo (4-day) - placebo (acute) PP, placebo (4-days) -caffeine (acute) PC, and caffeine (4-day) - caffeine (acute) CC. Participants abstained from dietary caffeine sources for 4 days and ingested capsules containing either placebo or caffeine (6 mg.kg-1 body mass day in one absorption). The acute trials the capsules containing placebo or caffeine (6 mg.kg-1 body mass day in one absorption) were ingested 60min before completing exercise in a treadmill for 40min (80% VO2max) and to perform the Wingate test. Results: Blood lactate was determined before, 60min after ingestion, and immediately after the exercise on the treadmill, the Wingate test, and after the recovery (10-min). CC and PC trials did not change the cardiopulmonary variables (P>0.05) and the anaerobic power variables (peak/mean power output and fatigue index) (P>0.05). The PC trial compared with PP promoted improvements in the curve power output in 2 sec by 31.19% (large effect-size d = 1.08; P<0.05) and 3 sec by 20% (large effect-size d = 1.19; P<0.05). A 10min recovery was not sufficient to reduce blood lactate concentration in the PC trial compared with PP (PC, 13.73±2.66 vs. PP, 10.26±1.60 mmol.L-1; P<0.05, respectively) (P<0.05). Conclusion: In conclusion, these results indicate that caffeine supplementation (6 mg·kg-1 body mass) for 4 days, followed by acute ingestion, did not impact the triathletes output power after performed submaximal intensity exercise. Nutritional interventions may help researchers and athletes to adapt strategies for manipulating caffeine use.Key-words: caffeine metabolism, Wingate test, blood lactate, performance.

A Comparison of Asynchronous and Synchronous Arm Cranking During the Wingate Test

2011 ◽  
Vol 6 (3) ◽  
pp. 419-426 ◽  
Author(s):  
Dale I. Lovell ◽  
Dale Mason ◽  
Elias Delphinus ◽  
Chris McLellan
Keyword(s):  
Blood Lactate ◽  
Peak Power ◽  
Anaerobic Power ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Wingate Test ◽  
Mean Power ◽  
Arm Cranking ◽  
Minimum Power ◽  
Time To Peak

Purpose:The aim of this study was to compare asynchronous (AS Y) arm cranking (cranks at 180° relative to each other) with synchronous (SYN) arm cranking (parallel crank setting) during the 30 s Wingate anaerobic test.Methods:Thirty-two physically active men (aged 22.1 ± 2.4 y) completed two Wingate tests (one ASY and one SYN) separated by 4 d in a randomized counterbalanced order. The Wingate tests were completed on a modified electromagnetically braked cycle ergometer. Performance measures assessed during the two tests include peak power, mean power, minimum power, time to peak power, rate to fatigue and maximum cadence (RPMmax). Blood lactate concentration was also measured before and 5 min after the tests.Results:Peak and mean power (both absolute and relative to body weight) during SYN arm cranking were significantly (p < 0.001) less than during ASY arm cranking. Rate to fatigue and RPMmax were also significantly (p = 0.012) lower during SYN arm cranking compared with ASY arm cranking. No significant difference was found between test conditions for minimum power, time to peak power or blood lactate concentration.Conclusions:These findings demonstrate that ASY arm cranking results in higher peak and mean anaerobic power compared with SYN arm cranking during the Wingate test. Therefore, an ASY arm crank configuration should be used to assess anaerobic power in most individuals although specific population groups may require further testing to determine which crank configuration is most suitable for the Wingate test.

scholarly journals Peak Power Output in the Bench Pull Is Maximized After Four Weeks of Specific Power Training

2016 ◽  
Vol 30 (4) ◽  
pp. 966-972
Author(s):  
Russell I. Jolley ◽  
Jon E. Goodwin ◽  
Daniel J. Cleather
Keyword(s):  
Power Output ◽  
Peak Power ◽  
Peak Power Output ◽  
Specific Power ◽  
Power Training

Abstract P134: Preliminary Data: Dietary Nitrate Supplementation Does Not Extend Dry Static Apnea Or Wingate Performance

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Colin Carriker ◽  
Phillip Armentrout ◽  
Sarah Levine ◽  
James Smoliga
Keyword(s):  
Power Output ◽  
Preliminary Data ◽  
Repeated Measures ◽  
Peak Power ◽  
Hold Time ◽  
Wingate Test ◽  
Peak Power Output ◽  
Breath Hold ◽  
Dietary Nitrate ◽  
Nitrate Supplementation

Introduction: Previous studies have examined dietary nitrate supplementation and its effects on dry static apnea, and peak power. Dietary nitrate supplementation has been found to increase maximal apnea and peak power output. The purpose of this study was to determine the effects of beetroot juice on dry static apnea and Wingate performance. Hypothesis: Dietary nitrate will improve maximal breath hold time and peak power output. Dietary nitrate will improve tolerance to CO2, thereby improving maximal breath hold time and anaerobic capacity. Methods: In a randomized, double-blind, counterbalanced study, five healthy males (20.4±0.89 years) visited the lab on 3 separate occasions each separated by one week. Visit 1 served as a Wingate and breath hold familiarization visit. Prior to visits 2 and 3 participants were instructed to drink a beverage either a placebo (negligible nitrate content, PL) or dietary nitrate rich beverage (12.4 mmol nitrate, NIT) during the 4 days leading up to their next visit. Visits 2 and 3 consisted of two submaximal breath holds (80% of maximal determined during visit 1), with 2 minutes of rest between and three minutes of rest preceding the final breath hold for maximal duration. Finally, participants completed a standardized 10-minute warmup on the cycle ergometer before completing a 30-second maximal effort Wingate test. Results: A linear mixed effects model was used to determine whether treatment (NIT vs. PL) was associated with differences in VCO2 or PetCO2. Time (0, 10, 20, 30 min post-breath hold) and Treatment both served as repeated measures. Models were developed using multiple repeated measures covariance matrix structures, and the model with the lowest AIC was chosen as the final model. The interaction between time and treatment was included in the original models, and was removed if it was not statistically significant. Time was a statistically significant factor for VCO2 and PetCO2 (p < 0.001). Treatment, and the Time x Treatment interaction was not significant for either variable. No differences between NIT and PL were observed during the Wingate test for either time to peak power (5.02±2.45 and 6.2±2.43 sec, respectively) or maximal power (9.73±1.01 and 9.72±1.03 watts/kg, respectively) and fatigue index (49.42±14.98 and 47.30±6.99 watts/sec, respectively). Conclusion: Preliminary data indicates that in a general population four days of dietary nitrate supplementation may not improve breath hold time, tolerance to carbon dioxide in the lungs, or Wingate performance.

Force-velocity and force-power properties of single muscle fibers from elite master runners and sedentary men

1996 ◽  
Vol 271 (2) ◽  
pp. C676-C683 ◽  
Author(s):  
J. J. Widrick ◽  
S. W. Trappe ◽  
D. L. Costill ◽  
R. H. Fitts
Keyword(s):  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Power Output ◽  
Peak Power ◽  
Isometric Force ◽  
Peak Force ◽  
Peak Power Output ◽  
Type I ◽  
Shortening Velocity ◽  
Force Velocity

Gastrocnemius muscle fiber bundles were obtained by needle biopsy from five middle-aged sedentary men (SED group) and six age-matched endurance-trained master runners (RUN group). A single chemically permeabilized fiber segment was mounted between a force transducer and a position motor, subjected to a series of isotonic contractions at maximal Ca2+ activation (15 degrees C), and subsequently run on a 5% polyacrylamide gel to determine myosin heavy chain composition. The Hill equation was fit to the data obtained for each individual fiber (r2 > or = 0.98). For the SED group, fiber force-velocity parameters varied (P < 0.05) with fiber myosin heavy chain expression as follows: peak force, no differences: peak tension (force/fiber cross-sectional area), type IIx > type IIa > type I; maximal shortening velocity (Vmax, defined as y-intercept of force-velocity relationship), type IIx = type IIa > type I; a/Pzero (where a is a constant with dimensions of force and Pzero is peak isometric force), type IIx > type IIa > type I. Consequently, type IIx fibers produced twice as much peak power as type IIa fibers, whereas type IIa fibers produced about five times more peak power than type I fibers. RUN type I and IIa fibers were smaller in diameter and produced less peak force than SED type I and IIa fibers. The absolute peak power output of RUN type I and IIa fibers was 13 and 27% less, respectively, than peak power of similarly typed SED fibers. However, type I and IIa Vmax and a/Pzero were not different between the SED and RUN groups, and RUN type I and IIa power deficits disappeared after power was normalized for differences in fiber diameter. Thus the reduced absolute peak power output of the type I and IIa fibers from the master runners was a result of the smaller diameter of these fibers and a corresponding reduction in their peak isometric force production. This impairment in absolute peak power production at the single fiber level may be in part responsible for the reduced in vivo power output previously observed for endurance-trained athletes.

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