scholarly journals AB0194 ASSOCIATION OF MALNUTRITION WITH QUALITY OF LIFE IN ELDERLY RA PATIENTS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1121.1-1121
Author(s):  
W. Tański ◽  
J. Wójciga ◽  
N. Świątoniowska-Lonc ◽  
B. Jankowska-Polańska

Background:Rheumatoid arthritis (RA) is a progressive joint condition that leads to joints destruction and complications in the internal organs and significantly affects the a patient’s functional ability. Elderly patients with RA complain of pain, mood and sleep disturbances, fatigue, and insomnia in addition to weakness, decreased appetite and weight loss. Chronic use of medications results in the risk of comorbidities and decreased physical functioning. All this together significantly contributes to a negative assessment of quality of life (QoL).Objectives:Due to the chronic nature of RA and the high risk of malnutrition in this group of patients, an attempt was made to assess the QoL, activities of daily living and severity of frailty syndrome according to the results of the MNA questionnaire in a group of elderly patients with RA.Methods:The study included 98 patients (age over 60 years) with a diagnosis of RA according to ARA. Standardized tools were used in the study: the WHOQOL-BREF to assess quality of life, the Edmonton Frailty Scale to assess frailty syndrome, MNA to assess nutritional status and MMSE to assess cognitive function. Medical data were taken from the hospital records.Results:Patients significantly differed in the extent of limitations in basic (ADL) and advanced activities of daily living (IADL) according to their nutritional status. The higher the level of malnutrition, the greater the limitations of undertaken activities. In addition, an adverse effect of reduced body weight on the occurrence of cognitive dysfunction was observed (33.33% of malnourished patients were diagnosed with dementia vs. 1.79% in normal weight patients). Similarly, frailty syndrome or vulnerability to frailty syndrome was associated with malnourished patients (33.3% mild, 16.67% moderate, and 16.67% severe frailty syndrome). Malnourished patients had significantly lower QoL scores in all domains of the WHOQOL-BREF questionnaire compared to normal weight patients and multivariate analysis of the effect of selected variables on QoL in the domains of the WHOQOL-BREF questionnaire showed that a significant independent determinant of lower QoL in all domains was the presence of frailty syndrome, respectively: Perception of QoL (R=-0. 069), Self-perception of health (R=-0.172), Physical domain (R=-0.425), Psychological domain (R=-0.432), Social domain (R=-0.415), Environmental domain (R=-0.317). Malnutrition was a significant independent determinant of QoL in the self-perception of health domain (R=-0.08). Additionally, in the regression analysis, a positive effect of male gender was observed on the assessment of QoL in the psychological (R=1.414) and environmental (R=1.123) domains.Table 5.Comparative analysis of quality of life in terms of each domain of the WHOQOL-BREF questionnaire according to nutritional status.WHOQOL BREFMNApMalnutrition (Mean±SD)Risk of malnutrition (Mean±SD)Normal nutrition (Mean±SD)Perception of quality of life3,33±1,033,33±0,683,68±0,580,029Self-perception of health2,67±0,822,47±0,843,14±0,980,004Physical health10,83±3,4911,31±2,3912,68±2,270,02Psychological domain12,5±3,8913,28±2,7314,45±2,240,056Social domain12,33± 2,8612,67±2,9314,29±2,610,007Environmental domain13,83±2,8613,22±2,2813,96±2,170,34Conclusion:Malnourished people have a lower quality of life than people of normal weight. Malnutrition is a factor that negatively affects daily functioning, cognitive functioning, and the severity of frailty syndrome. A significant independent determinant of reduced quality of life across all domains of the WHOQOL-BREF questionnaire is frailty syndrome.References:[1]Marcora SM, Chester KR, Mittal G et al. Randomizedphase 2 trial of anti-tumor necrosisfactortherapy for cachexia in patients with earlyrheumatoidarthritis. Am J ClinNutr 2006;84:1463–72. 24 .[2]Kremers HM, Nicola PJ, Crowson CS, et al. Prognosticimportance of low body mass index in relation to cardiovascularmortality in rheumatoidarthritis. ArthritisRheum. 2004;50:3450–7.Disclosure of Interests:None declared

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1259
Author(s):  
Wojciech Tański ◽  
Justyna Wójciga ◽  
Beata Jankowska-Polańska

Rheumatoid arthritis (RA) is a progressive articular disease. In addition to damaging the joints, it may cause multiple organ complications, and considerably impair the patient’s functioning. Elderly patients with RA report pain, fatigue, mood disorders, sleep disorders and insomnia, accompanied by weakness, poor appetite, and weight loss. All these factors combined have an adverse effect on the patient’s perceived quality of life (QoL). Due to the chronic nature of RA and the high risk of malnutrition in this patient group, the present study investigated QoL, activities of daily living, and frailty syndrome severity in relation to MNA (Mini Nutritional Assessment) questionnaire scores among elderly RA patients. The study included 98 patients (aged over 60) diagnosed with RA per the ARA (American Rheumatism Association) criteria. The following standardized instruments were used: WHOQoL-BREF for QoL, the Edmonton Frail Scale for frailty syndrome severity, MNA for nutritional status assessment, and MMSE (Mini-Mental State Examination) to assess any cognitive impairment. Medical data were obtained from hospital records. Patients with a different nutritional status differed significantly in terms of limitations in activities of daily living (ADL) and instrumental activities of daily living (IADL). Higher levels of malnutrition were associated with greater limitations in activity. An adverse impact of lower body weight on cognitive function was also observed (dementia was identified in 33.33% of malnourished patients vs. 1.79% in patients with a normal body weight). Likewise, frailty was more common in malnourished patients (mild frailty syndrome in 33.3%, moderate in 16.67%, and severe in 16.67%). Malnourished patients had significantly lower QoL scores in all WHOQoL-BREF questionnaire domains than those with a normal body weight, and multiple-factor analysis for the impact of selected variables on QoL in each domain demonstrated that frailty was a significant independent determinant of poorer QoL in all domains: perceived quality of life (β = −0.069), perceived health (β = −0.172), physical domain (β = −0.425), psychological domain (β = −0.432), social domain (β = −0.415), environmental domain (β = −0.317). Malnutrition was a significant independent determinant of QoL in the “perceived health” domain (β = −0.08). In addition, regression analysis demonstrated the positive impact of male sex on QoL scores in the psychological (β = 1.414) and environmental domains (β = 1.123). Malnourished patients have a lower QoL than those with a normal body weight. Malnutrition adversely affects daily functioning, cognitive function, and the severity of frailty syndrome. Frailty syndrome is a significant independent determinant of poorer QoL in all WHOQoL BREF domains.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S M Aguiar Lemos ◽  
L J Vasconcellos ◽  
R Tavares ◽  
A G Escarce ◽  
E M Melo

Abstract Objective To investigate self-perceived health, quality of life and its association with social determinants in adults and the elderly. Methods Observational analytical cross-sectional study, with a probabilistic sample of 1,129 participants, adults and seniors, stratified by conglomerates, living in a municipality in Minas Gerais, Brazil. The response variables were the questions: 'How do you evaluate your health in the last two months?' and 'How do you evaluate your quality of life in the last two months?'. The explanatory variables were sociodemographic and technical-assistance data. For data analysis, a descriptive analysis of categorical and continuous variables and an association analysis (Chi-Square Pearson test) were performed, statistically significant those with a value of p0.05. Results The majority were female, classified the quality of life as good and presented positive self-perception of health. Most were aged between 30 and 39 years old, attended high school, were married, had formal work and family income of up to one minimum wage. The association between self-perceived health and quality of life with social determinants revealed that the interviewees who tended to present positive self-perception of health were female, had up to 39 years of age, studied until high school, received up to five minimum wages and had had between one and two medical consultations in the last 12 months. Regarding quality of life, the interviewees who reported there were good were female, between 30 and 39 years old, with high school, were married, had formal work, received up to two minimum wages and had between one and two medical consultations at last year. The univariate analysis revealed that respondents who said their health was positive also rated the quality of life as good. Conclusions In the sample studied, it was observed that positive self-perception of health is associated with good quality of life. Key messages Health public. Quality of life.


2010 ◽  
Vol 36 (4) ◽  
pp. 305-311 ◽  
Author(s):  
M.M. Esteban y Peña ◽  
V. Hernandez Barrera ◽  
X. Fernández Cordero ◽  
A. Gil de Miguel ◽  
M. Rodríguez Pérez ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Rosa M. Martínez-Piédrola ◽  
Cristina García-Bravo ◽  
Elisabet Huertas-Hoyas ◽  
Patricia Sánchez-Herrera Baeza ◽  
Jorge Pérez-Corrales ◽  
...  

Background. Multiple sclerosis is a disorder which causes a loss of functionality, affecting the person’s ability to perform activities of daily living, such as interpersonal interactions and relationship, dressing, self-care, or bathing, as well as having a negative impact on work and leisure activities. Aims. This study examined the relationship (correlational or associations/predictive) between self-perceived quality of life and performance of manipulative dexterity. Also, this study sought to measure predictors of dexterity. Study Design. A cross-sectional study from two associations of MS within the Community of Madrid, Spain. Methods and Procedures. A final sample of 30 people with multiple sclerosis. The outcome measures used were the ABILHAND questionnaire, the Purdue Pegboard Test, the Nine Hole Peg Test, and the Box and Block Test. Results. No significant correlations were found between dexterity and self-perception tests; however, correlations were found between perceived dexterity and quality of life ( p < 0.001 ). Scores for the ABILHAND questionnaire, which measures the perception of skills in daily living, predicted up to 60% of the variance in the dexterity tests. Conclusions. The results of this study suggest that interventions for improving the manipulative dexterity of people with multiple sclerosis should address the person’s perception of improving their manipulative dexterity and the perceived of quality of life, as both factors may influence manipulative dexterity.


2016 ◽  
Vol 8 (1) ◽  
pp. 40-46
Author(s):  
Yoshihiro Tominaga ◽  
Manabu Okada ◽  
Takayuki Yamamoto ◽  
Takahisa Hiramitsu

ABSTRACT BACKGROUND AND AIMS The number of elderly patients with primary hyperparathyroidism (PHPT) has been increasing as a result of declining birth rate and aging population in Japan. The safety and effectiveness of surgical treatment in old people with PHPT are still contentious. METHODS We retrospectively investigated the characteristics and postoperative course in 55 patients over 70 years of age who underwent parathyroidectomy (PTX) for PHPT at our institution from February 1988 to May 2015. RESULTS Forty-four of the 55 patients had comorbidities such as hypertension, diabetes, and so on. In all the cases, PTX was successfully performed and the serum levels of parathyroid hormone and calcium lowered. Neuropsychiatric symptoms also improved in 14 patients after PTX. Except two cases, no severe complication occurred after PTX: one developed aspiration pneumonitis and one needed hemodialysis for acute exacerbation in chronic kidney disease. CONCLUSION Active and appropriate application of PTX might contribute to improvements in the activities of daily living and quality of life in elderly patients with PHPT.


2013 ◽  
Vol 18 (2) ◽  
pp. 192-197 ◽  
Author(s):  
R. Artacho ◽  
C. Lujano ◽  
A. B. Sanchez-Vico ◽  
C. Vargas Sanchez ◽  
J. Gonzalez Calvo ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Qi Zhang ◽  
Liang Qian ◽  
Tong Liu ◽  
Jia-Shan Ding ◽  
Xi Zhang ◽  
...  

Background: Malnutrition is common in patients with cancer and is associated with adverse outcomes, but few data exist in elderly patients. The aim of this study was to report the prevalence of malnutrition using three different scoring systems and to examine the possible clinical relationship and prognostic consequence of malnutrition in elderly patients with cancer.Methods: Nutritional status was assessed by using controlling nutritional status (CONUT), the prognostic nutritional index (PNI), and the nutritional risk index (NRI). Quality-of-life (Qol) was assessed during admission by using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C-30. Performance status (PS) was assessed by using the Eastern Cooperative Oncology Group (ECOG) classification. The relationship between nutritional status and overall survival and Qol were examined.Results: Data were available for 1,494 elderly patients with cancer (63.65% male), the mean age was 70.76 years. According to the CONUT, NRI, and PNI, 55.02, 58.70, and 11.65% patients were diagnosed with malnutrition, respectively. Worse nutritional status was related to older, lower BMI, lower hand grip strength, and more advanced tumor stage. All malnutrition indexes were correlated with each other (CONUT vs. PNI, r = −0.657; CONUT vs. NRI scores, r = −0.672; PNI vs. NRI scores, r = 0.716, all P &lt; 0.001). During a median follow-up of 43.1 months, 692 (46.32%) patients died. For patients malnourished, the incidence rate (events-per-1,000person-years) was as follows: CONUT (254.18), PNI (429.91), and NRI (261.87). Malnutrition was associated with increased risk for all-cause mortality (adjust HR [95%CI] for CONUT: 1.09 [1.05–1.13], P &lt; 0.001; PNI: 0.98[0.97–0.99], P &lt; 0.001; NRI: 0.98 [0.98–0.99], P &lt; 0.001). All malnutrition indexes improved the predictive ability of the TNM classification system for all-cause mortality. Deterioration of nutritional status was associated with deterioration in Qol parameters and immunotherapeutic response (P &lt; 0.001).Conclusions: Malnutrition was prevalent in elderly patients with cancer, regardless of the assessment tools used, and associated with lower Qol and the immunotherapy response.


Revista CEFAC ◽  
2018 ◽  
Vol 20 (5) ◽  
pp. 604-612
Author(s):  
Stela Maris Aguiar Lemos ◽  
Poliana Cristina Rocha ◽  
Angel Martínez-Hernaéz

ABSTRACT Purpose: to verify the association between self-perception of health, gender, age, economic status, quality of life, cultural aspects and contexts of violence in high school adolescents. Methods: an observational analytical cross-sectional study with a probabilistic sample composed of 386 high school students aged 15-19 years. The data collection was made in 16 public schools. Descriptive, bivariate and multivariate data analyses were made. Models with hierarchical entry of the blocks according to the level of determination established in the theoretical model were built, and for the evaluation of associations in the logistic regression models, the significance level of 5% was considered. The Odds Ratio and its respective confidence interval of 95% were used as a measure of the magnitude of the associations. Results: the data revealed that more than two-thirds of the participants reported a positive self-perception of health and, in the hierarchical multiple logistic regression model, to have own house, to practice any religion, and the quality of life remained associated with positive Self-perception of health. Conclusion: having their own house, practicing a given religion and having a better quality of life increased the chances of a positive self-perception of health.


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