scholarly journals School-age outcomes of children without cerebral palsy cooled for neonatal hypoxic–ischaemic encephalopathy in 2008–2010

Author(s):  
Richard Lee-Kelland ◽  
Sally Jary ◽  
James Tonks ◽  
Frances M Cowan ◽  
Marianne Thoresen ◽  
...  

ObjectiveSince therapeutic hypothermia became standard care for neonatal hypoxic–ischaemic encephalopathy (HIE), even fewer infants die or have disability at 18-month assessment than in the clinical trials. However, longer term follow-up of apparently unimpaired children is lacking. We investigated the cognitive, motor and behavioural performances of survivors without cerebral palsy (CP) cooled for HIE, in comparison with matched non-HIE control children at 6–8 years.DesignCase–control study.Participants29 case children without CP, cooled in 2008–2010 and 20 age-matched, sex-matched and social class-matched term-born controls.MeasuresWechsler Intelligence Scales for Children, Fourth UK Edition, Movement Assessment Battery for Children, Second Edition (MABC-2) and Strengths and Difficulties Questionnaire.ResultsCases compared with controls had significantly lower mean (SD) full-scale IQ (91 [10.37]vs105[13.41]; mean difference (MD): −13.62, 95% CI −20.53 to –6.71) and total MABC-2 scores (7.9 [3.26]vs10.2[2.86]; MD: −2.12, 95% CI −3.93 to –0.3). Mean differences were significant between cases and controls for verbal comprehension (−8.8, 95% CI –14.25 to –3.34), perceptual reasoning (−13.9, 95% CI–20.78 to –7.09), working memory (−8.2, 95% CI–16.29 to –0.17), processing speed (−11.6, 95% CI–20.69 to –2.47), aiming and catching (−1.6, 95% CI–3.26 to –0.10) and manual dexterity (−2.8, 95% CI–4.64 to –0.85). The case group reported significantly higher median (IQR) total (12 [6.5–13.5] vs 6 [2.25–10], p=0.005) and emotional behavioural difficulties (2 [1–4.5] vs 0.5 [0–2.75], p=0.03) and more case children needed extra support in school (34%vs5%, p=0.02) than the control group.ConclusionsSchool-age children without CP cooled for HIE still have reduced cognitive and motor performance and more emotional difficulties than their peers, strongly supporting the need for school-age assessments.

2020 ◽  
Author(s):  
Arthur P.C. Spencer ◽  
Jonathan C.W. Brooks ◽  
Naoki Masuda ◽  
Hollie Byrne ◽  
Richard Lee-Kelland ◽  
...  

AbstractTherapeutic hypothermia following neonatal encephalopathy due to birth asphyxia reduces death and cerebral palsy. However, school-age children without cerebral palsy treated with therapeutic hypothermia for neonatal encephalopathy still have reduced performance on cognitive and motor tests, attention difficulties, slower reaction times and reduced visuo-spatial processing abilities compared to typically developing controls. We acquired diffusion-weighted imaging data from school-age children without cerebral palsy treated with therapeutic hypothermia for neonatal encephalopathy at birth, and a matched control group. Voxelwise comparison of fractional anisotropy (33 cases, 36 controls) confirmed microstructural alterations in widespread areas of white matter in cases, particularly in the fornix, corpus callosum, anterior and posterior limbs of the internal capsule bilaterally and cingulum bilaterally. In structural brain networks constructed using probabilistic tractography (22 cases, 32 controls), graph-theoretic measures of strength, local and global efficiency, clustering coefficient and characteristic path length were found to correlate with IQ in cases but not controls. Network-based statistic analysis implicated brain regions involved in visuo-spatial processing and attention, aligning with previous behavioural findings. These included the precuneus, thalamus, left superior parietal gyrus and left inferior temporal gyrus. Our findings demonstrate that, despite the manifest successes of therapeutic hypothermia, brain development is impaired in these children.


2021 ◽  
Vol 11 (5) ◽  
pp. 539
Author(s):  
Tamara Jakovljević ◽  
Milica M. Janković ◽  
Andrej M. Savić ◽  
Ivan Soldatović ◽  
Gordana Čolić ◽  
...  

Reading is one of the essential processes during the maturation of an individual. It is estimated that 5–10% of school-age children are affected by dyslexia, the reading disorder characterised by difficulties in the accuracy or fluency of word recognition. There are many studies which have reported that coloured overlays and background could improve the reading process, especially in children with reading disorders. As dyslexia has neurobiological origins, the aim of the present research was to understand the relationship between physiological parameters and colour modifications in the text and background during reading in children with and without dyslexia. We have measured differences in electroencephalography (EEG), heart rate variability (HRV), electrodermal activities (EDA) and eye movements of the 36 school-age (from 8 to 12 years old) children (18 with dyslexia and 18 of control group) during the reading task in 13 combinations of background and overlay colours. Our findings showed that the dyslexic children have longer reading duration, fixation count, fixation duration average, fixation duration total, and longer saccade count, saccade duration total, and saccade duration average while reading on white and coloured background/overlay. It was found that the turquoise background, turquoise overlay, and yellow background colours are beneficial for dyslexic readers, as they achieved the shortest time duration of the reading tasks when these colours were used. Additionally, dyslexic children have higher values of beta (15–40 Hz) and the broadband EEG (0.5–40 Hz) power while reading in one particular colour (purple), as well as increasing theta range power while reading with the purple overlay. We have observed no significant differences between HRV parameters on white colour, except for single colours (purple, turquoise overlay, and yellow overlay) where the control group showed higher values for mean HR, while dyslexic children scored higher with mean RR. Regarding EDA measure, we found systematically lower values in children with dyslexia in comparison to the control group. Based on the present results, we can conclude that both pastel and intense background/overlays are beneficial for reading of both groups and all sensor modalities could be used to better understand the neurophysiological origins in dyslexic children.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Sri Aminingsih ◽  
Warsini

Latar belakang : kebiasaan cuci tangan yang benar sangat penting. Namun menurut Badan Pusat Statistik kebiasaan cuci tangan yang benar di Provinsi Jawa Tengah belum maksimal yaitu sebesar 53,6%. Dari observasi yang dilakukan peneliti di Dusun Ngegot Kabupaten Karanganyar masih terlihat bahwa beberapa anak saat membeli jajanan langsung mengonsumsi jajanan tersebut tanpa mencuci tangan terlebih dahulu, padahal masing-masing rumah sudah menyediakan tempat cuci tangan di depan rumah. Tujuan : untuk mengetahui pengaruh penerapan metode bernyanyi terhadap kemampuan cuci tangan pada anak usia sekolah. Metode : penelitian ini merupakan penelitian eksperimental dengan desain pre-post experimental control design untuk mengetahui pengaruh metode bernyanyi dalam meningkatkan kemampuan cuci tangan anak usia sekolah. Hasil : hasil pretest pada kelompok perlakuan terdapat 93,3% anak yang tidak mampu melakukan cuci tangan dengan benar dan 6,7% anak yang mampu melakukan cuci tangan dengan benar dan hasil posttest  terdapat 20% anak yang tidak mampu melakukan cuci tangan dengan benar dan 80% anak yang mampu melakukan cuci tangan dengan benar. Sedangkan pada kelompok kontrol hasil pretest terdapat 93,3% anak yang tidak mampu melakukan cuci tangan dengan benar dan 6,7% anak yang mampu melakukan cuci tangan dengan benar dan hasil posttest  terdapat 60% anak yang tidak mampu melakukan cuci tangan dengan benar dan 40% anak yang mampu melakukan cuci tangan dengan benar. Dengan menggunakan Uji Mann Whitney diperoleh hasil p = 0,028. Kesimpulan : penerapan metode bernyanyi efektif untuk meningkatkan kemampuan mencuci tangan. Kata kunci : kemampuan mencuci tangan, metode bernyanyi, penerapan   Background : correct hand washing habits are very important. However, according to the Central Statistics Agency, the correct habit of washing hands in Central Java Province is not maximal, namely at 53.6%. From observations made by researchers in Ngegot, Karanganyar Regency, it is still seen that some children when buying snacks immediately consume these snacks without washing their hands first, even though each house has provided a place to wash their hands in front of the house. The aims of the study : this is to determine the effect of the singing method on the ability to wash hands in school age children. Method. This research is an experimental study with a pre-post experimental control design to determine the effect of the singing method in improving the ability of school age children to wash their hands. Result : the pretest results in the treatment group were 93.3% of children who were unable to wash their hands properly and 6.7% of children who were able to wash their hands properly and posttest results there were 20% of children who were unable to wash their hands properly and 80% children who are able to wash their hands properly. Whereas in the control group, the pretest results were 93.3% of the children who were unable to wash their hands properly and 6.7% of the children who were able to wash their hands properly and the posttest results there were 60% of the children who were unable to wash their hands properly and 40 % of children who are able to wash their hands properly. By using the Mann Whitney test the result was p = 0.028. Conclusion : the application of the singing method is effective in improving the ability to wash hands. Key words: ability to wash hands, singing method, application


2018 ◽  
Vol 15 (2S) ◽  
pp. 58-64
Author(s):  
V. V. Li ◽  
G. P. Smoliakova ◽  
V. V. Egorov ◽  
O. I. Kashura

Purpose:to study the frequency and structure of undifferentiated connective tissue dysplasia (UCTD) in school-age children with myopia, their relationship to choroidal thickness and course of myopia.Patients and methods. The object of study was 120 children (240 eyes) aged 11–13 years with school axial myopia (axial length (AL) from 24.5 to 26.0 mm). Special ophthalmological examination included optical coherent tomography of macular zone (“RTVue 100” Optovue, USA) and “Cross Line” scan for measuring choroidal thickness in foveal area and 1000 μm from it in nasal and temporal regions.Results.According to studies, the phenotypic signs of UCTD were diagnosed in 56 children (46.7%) with school myopia, the largest group included phenotypic signs of locomotor syndrome; 14 children (25%) had a weak degree of UCTD, 34 children (60.7%) — moderate degree and 8 children (14.3%) — pronounced degree. Comparative characteristic of changes in choroidal thickness detected a high degree of interrelation between the severity of clinical manifestations of UCTD and the level of decrease in blood-flow in the choroid. In children of the main group with signs of UCTD, the annual growth of AL exceeded the same parameters in children of the control group by more than 2.5 times (p < 0.05); due of accumulation of phenotypic signs of UCTD, a more noticeable tendency to decrease of choroidal thickness and the increase of AL was observed (p < 0.05). The statistical analysis confirmed the presence of significant negative correlation between the decrease in average thickness index in segment of the macular map and the degree of increase of AL (p < 0.05).Conclusions. According to results of diagnostic screening, in 46.7% children with school myopia, we detected phenotypic signs of UCTD. The method of optical coherence tomography showed that with increasing severity of UCTD, indexes of choroidal thickness in the macular zone are significant decreased. In the catamnesis (duration 1 year), it was found that in children with myopia with moderate and pronounced degrees of UCTD, increase of AL is associated with degree of thinning choroidal thickness, which indicates violations of biomechanical status of sclera. 


2019 ◽  
Vol 34 (7) ◽  
pp. 1254-1254
Author(s):  
A Giudicessi ◽  
V D Visconti ◽  
A Zenit Aldana ◽  
C Ibarra

Abstract Objective The Wechsler Scale of Intelligence for Children (WISC-IV) is one of the most commonly used intelligence tests for children. A Spanish version of the WISC-IV exists, but a limited amount of published information is available on its utility when assessing pediatric clinical populations. Furthermore, little published research utilizes the WISC-IV in Spanish speaking populations residing outside the US. This study seeks to present the neuropsychological profile of a clinically referred sample of children residing in Mexico. Participants and Method The present study included 35 participants (15 females and 20 males, M age of 9.26 years, SD = 1.69). Participants were referred to clinic sites affiliated with the neuropsychology master’s program at Benemérita Universidad Autónoma de Puebla (BUAP). Participants were referred for assessment due to persistent academic/behavior difficulties and were included in this study if they were between the ages of 7 and 12, with no history of a psychiatric disorder. All participants were administered the WISC-IV. Procedures were approved by the ethics committee at BUAP. Informed consent was obtained prior to evaluation. Results Descriptive statistics show a Full-Scale IQ average (FSIQ) mean of 75.40 (SD = 12.42). Highest index scores were on Perceptual Reasoning (PRI) (M = 84.94, SD = 16.22) and Processing Speed (PSI) (M = 81.34, SD = 12.96) and lowest index score were on working memory (WMI) (M = 76.97, SD = 14.64) and Verbal Comprehension (VCI) (M = 76.54, SD = 12.42). Independent T-Tests showed no significant differences between genders. Conclusions Our results show a low average IQ for the sample but also identifies strengths in certain indices and specific subtests within the WISC-IV that can add rich details in the comprehension of cognitive functioning in this sample. In the future, we plan to continue the growth of our study via the utilization of a control group to compare with the clinical sample.


2017 ◽  
Vol 70 (6) ◽  
pp. 1244-1249 ◽  
Author(s):  
Sabrina Gisele Tobias da Silva ◽  
Maiara Aurichio Santos ◽  
Claudia Maria de Freitas Floriano ◽  
Elaine Buchhorn Cintra Damião ◽  
Fernanda Vieira de Campos ◽  
...  

ABSTRACT Objective: To evaluate the effects of Dramatic Therapeutic Play (DTP) technique on the degree of anxiety in hospitalized school-age children. Method: Randomized clinical trial performed in two hospitals ofSão Paulo, between May and October 2015. The intervention consisted of the application of DTP and the outcome was evaluated through the Child Drawing: Hospital (CD: H) instrument. The Wilcoxon-Mann Whitney, Corrected t, Fisher’s exact and Chi-square tests were used in the analysis. Statistical significance was set at 5%. Results: In all, 28 children participated in the study. The majority of children (75%) had a low anxiety score, with a mean CD: H score of 73.9 and 69.4 in the intervention and control groups respectively, and with no significant difference. Conclusion: Children submitted to DTP had the same degree of anxiety as those in the control group. However, it is suggested that new studies be performed with a larger number of children in different hospitalization scenarios.


Author(s):  
Ni Ketut Mendri ◽  
◽  
Atik Badi’ah ◽  
Mohammad Najib ◽  
◽  
...  

ABSTRACT Background: Children who are first hospitalized may experience higher anxiety levels than children who have been hospitalized. The preliminary study in 2018 showed that when general surgery was to be done, as many as 90%school-age children were scared and nervous. It is important to provide play therapy to children who are going to undergo surgery. In addition to reading and seeing through photos, pop-up toy story books will also be offered to school-age children. This study aimed to examine the relationship between pop up toys as story play therapy on the level of anxiety on general anesthesia surgery among children around 6-12 years old. Subjects and Method: This was an experimental study with pre-post test with control group design. This study was conducted in Yogyakarta Province hospital. Study subjects were children around 6-12 years old and will performed general anesthesia surgery. The data were collected using questioner and in-depth interview. The data were analyzed using Mann-Whitney test. Results: There was a decrease number of children with moderate level of anxiety after the intervention group using pop up toys as story play therapy from 30 children (81.1%) to 6 children (16.2%). While in the control group, a total of 25 children had moderate level of anxiety (87.6%) before the theraphy, and after therapy a total of 2 children also had moderate level of anxiety (5.4%), and they were statistically significant. Conclusion: Playing pop up toys story therapy has an effect on the level of anxiety among children around 6-12 years old and will performed general anesthesia surgery. Keywords: pop up toys story therapy, anxiety level, general anesthesia, school age children Correspondence: Ni Ketut Mendri. School of Health Sciences, Yogyakarta. Email: [email protected] DOI: https://doi.org/10.26911/the7thicph.03.29


2019 ◽  
Vol 38 (3) ◽  
pp. 578-589
Author(s):  
Iswinarti Iswinarti ◽  
Dewi Retno Suminar

Nowadays, most children play digital games. Digital games, despite their advantages, have gradually eroded the existence of traditional games. Although both digital and traditional games comprise the values of problem-solving learning for children, traditional games offer more benefits in terms of the embodiment of local wisdom. This study aimed at encompassing the influence of Javanese traditional games such as bekelan, congklak lidi, and selentikan on the improvement of children’s problem-solving skills. This research was done employing quasi-experimental design involving 72 school-age children ranging from 9 to 11 years old, who studied at primary schools. The subjects of this study consisted of four experimental groups. Three groups played bekelan, congklak lidi, selentikan games respectively and the other group was assigned as the control group. The treatment was done for three weeks divided into six sessions. The findings showed that there was a significant improvement between the result of the pre-test and that of the post-test for these three games. The analysis results using One Way ANOVA showed that there was a difference in the improvement of problem-solving skills among groups (F(17) = 5.032, p < .01). Due to its superiority, Javanese traditional games are potential to be an alternative media in improving children’s problem-solving skills.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Mehdi Ramezani ◽  
Jandark Eghlidi ◽  
Ehsan Pourghayoomi ◽  
Saeed Mohammadi

Background. Literature indicated some risk factors for low back pain; however, there is insufficient knowledge on the effect of caring-related physical activities and individual characteristics on Chronic Low Back Pain (CLBP) in mothers of children with Cerebral Palsy (CP). Objective. The main aim of the current study was to determine the association between caring-related physical activities, Body Mass Index (BMI), education level, and CLBP in mothers of children with CP. Design. Case-control observational study. Setting. Pediatric rehabilitation clinics. Participants. Mothers of children with CP. Main Outcome Measures. Measures is comprised of a self-administered questionnaire that included the demographic characteristics items, pain visual analog scale, and three items of the job-related physical demands questionnaire. The logistic regression model served to assess the association. Results. The control group included 81 healthy mothers, with a mean (SD) age of 39 (8.45) years, and the case group contained 90 mothers who suffered from CLBP, with a mean (SD) age of 37 (8.64) years. Performing lifting movements (OR 13.73, β = 2.62 , p < .001 ), BMI (OR 11.85, β = 2.47 , p = .011 ), repetitive bending (OR 7.67, β = 2.04 , p = .010 ), forward-flexion (OR 6.71, β = 1.91 , p = .033 ), and level of education (OR .21, β = − 1.53 , p = .020 ), in descending order of odds ratios, were found to be significant predictors of the CLBP in mothers of children with CP. Conclusion. Avoiding caring-related harmful physical activities, maintaining body weight within a healthy range, and increasing knowledge for accurate lifting/handling techniques can be helpful to prevent the CLBP in mothers of children with CP.


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