Role of vaccinations as risk factors for ill health in veterans of the Gulf war: cross sectional study

This comparative cross-sectional study aimed to better understand the respective contributions of protein malnutrition and cassava-derived cyanide poisoning in the development of konzo. We compared data on nutritional status and cyanide exposure of school-age adolescent konzo-diseased patients to those of non-konzo subjects of similar age from three areas in the Eastern Democratic Republic of the Congo. Our results show that konzo patients had a high prevalence of both wasting (54.5%) and stunting (72.7%), as well as of cyanide poisoning (81.8%). Controls from Burhinyi and those from Idjwi showed a similar profile with a low prevalence of wasting (3.3% and 6.5%, respectively) and intermediate prevalence of stunting (26.7% and 23.9%, respectively). They both had a high prevalence of cyanide poisoning (50.0% and 63.0%, respectively), similar to konzo-patients. On the other hand, controls from Bukavu showed the lowest prevalence of both risk factors, namely chronic malnutrition (12.1%) and cyanide poisoning (27.6%). In conclusion, cassava-derived cyanide poisoning does not necessarily coexist with konzo outbreaks. The only factor differentiating konzo patients from healthy individuals exposed to cyanide poisoning appeared to be their worse nutritional status. This further suggests that, besides the known role of cyanide poisoning in the pathogenesis of konzo, malnutrition may be a key factor for the disease occurrence.

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Risk factors associated with sensitive skin and potential role of lifestyle habits: a cross-sectional study

Clinical and Experimental Dermatology ◽

10.1111/ced.13133 ◽

2017 ◽

Vol 42 (6) ◽

pp. 656-658 ◽

Cited By ~ 6

Author(s):

D. Falcone ◽

R. J. H. Richters ◽

N. E. Uzunbajakava ◽

P. E. J. van Erp ◽

P. C. M. van de Kerkhof

Keyword(s):

Risk Factors ◽

Potential Role ◽

Cross Sectional Study ◽

Sectional Study ◽

Sensitive Skin ◽

Lifestyle Habits ◽

Cross Sectional ◽

Factors Associated

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Role of Inflammation on the Control of the Arterial Hypertension among Patients with Metabolic Syndrome.

Clinical Cardiology and Cardiovascular Interventions ◽

10.31579/2641-0419/035 ◽

2021 ◽

Vol 3 (3) ◽

pp. 01-05

Author(s):

Ylber Jani ◽

Atila Rexhepi ◽

Bekim Pocesta ◽

Ahmet Kamberi ◽

Fatmir Ferati ◽

...

Keyword(s):

Risk Factors ◽

Cross Sectional Study ◽

Vital Role ◽

Good Evidence ◽

Sectional Study ◽

Cross Sectional ◽

Study Population ◽

Independent Association ◽

Current Guidelines

BACKGROUND: It is widely accepted that hypertension is a pro-inflammatory disease and that the immune system plays a vital role in mediating hypertensive outcomes, end organ damages . and modulation of hypertensive pathology [2]. Patient with MetS usually present increased levels of C-reaktive protein (CRP) wich is a prototypic marker of inflammation [5], however the data of the influence of incresed levels of CRP on the control of the aterial hypertension in patients with MetS, are scarce. OBJECTIVE: We sought to determine the incresed CRP levels influence on the control of the aterial hypertension in patients with MetS. METHODS: We conducted a multicenter observational cross-sectional study. The study population recruited from a coule of outpatient clinic between june 2018 and june 2019. The population study consisted of 420 patients with MetS aged ≥ 18 years, divided in two groups:211 with level of CRP>3mg/l , and 209 participans with CRP level <3mg/l. RESULTS: Among those with CRP level > 3mg/l(N=211) controlled BP according to evidence and current guidelines, was achieved in 23.6% of participans, whereas among those with CRP level <3mg/l(N=209) controlled BP was achived in 48.3%; p=0.000). There was independent association of CRP levels >3mg/l with uncontrolled BP (OR=3.1, 95%CI 2.06 - 4.75). There were signifiacant association of uncontrolled BP with: uncontrolled glycemia (OR =1.4,95%CI 0.97-1.84); increased BMI (OR=4.4; 95%CI 3.02-4.05) and five risk factors for MetS.(OR=2.3, 95%CI 1.93-2.81). CONCLUSIONS: We think,we brought some good evidence,in our present study ,that patients with MetS and higher CRP level have a higher prevalence of unconrolled BP.

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Prevalence and Risk Factors of Frailty in a Community-Dwelling Population: The HELIAD Study

Journal of Aging and Health ◽

10.1177/0898264318801735 ◽

2018 ◽

Vol 32 (1-2) ◽

pp. 14-24 ◽

Cited By ~ 2

Author(s):

E. Ntanasi ◽

M. Yannakoulia ◽

N. Mourtzi ◽

G. S. Vlachos ◽

M. H. Kosmidis ◽

...

Keyword(s):

Risk Factors ◽

Population Studies ◽

Frailty Index ◽

Cross Sectional Study ◽

Community Dwelling ◽

Sectional Study ◽

Cross Sectional ◽

Tilburg Frailty Indicator ◽

Frailty Indicator

Objective: To estimate the prevalence of frailty using five different instruments in a cohort of older adults and explore the association between frailty and various risk factors. Method: 1,867 participants aged 65 years and above were included in the current retrospective cross-sectional study. Frailty was operationalized according to the Fried definition, the FRAIL Scale, the Frailty Index (FI), the Tilburg Frailty Indicator (TFI), and the Groningen Frailty Index (GFI). We explored the role of various frailty risk factors using logistic regression analyses. Results: The prevalence of frailty varied depending on the definition used (Fried definition = 4.1%, FRAIL Scale = 1.5%, FI = 19.7%, TFI = 24.5%, and GFI = 30.2%). The only risk factors consistently associated with frailty irrespectively of definition were education and age. Conclusion: The frailty prevalence reported in our study is similar or lower to that reported in other population studies. Qualitative differences between frailty definitions were observed.

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A cross-sectional study of geographic differences in health risk factors among young Australian adults: The role of socioeconomic position

BMC Public Health ◽

10.1186/1471-2458-14-1278 ◽

2014 ◽

Vol 14 (1) ◽

Cited By ~ 13

Author(s):

Kira AE Patterson ◽

Verity Cleland ◽

Alison Venn ◽

Leigh Blizzard ◽

Seana Gall

Keyword(s):

Risk Factors ◽

Health Risk ◽

Socioeconomic Position ◽

Cross Sectional Study ◽

Sectional Study ◽

Health Risk Factors ◽

Cross Sectional ◽

Geographic Differences

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Leptospirosis as a neglected burden at human-cattle interface in Mid-Delta of Egypt

The Journal of Infection in Developing Countries ◽

10.3855/jidc.13231 ◽

2021 ◽

Vol 15 (05) ◽

pp. 704-709

Author(s):

Yamen Hegazy ◽

Walid Elmonir ◽

Atef Fatehy Orieby ◽

Ibrahim E Eldesoukey ◽

Maryan Fransis ◽

...

Keyword(s):

Risk Factors ◽

Developing Countries ◽

Viral Hepatitis ◽

Cross Sectional Study ◽

Leptospira Interrogans ◽

Sectional Study ◽

Cross Sectional ◽

Study Region ◽

Associated Risk Factors

Introduction: Leptospirosis is a neglected zoonosis in developing countries including Egypt where its burden is underestimated. Methodology: A cross sectional study was carried out to estimate the seroprevalence and associated risk factors of Leptospira interrogans serovar Hardjo infection among cows and leptospirosis among human patients in Mid-Delta of Egypt. Results: Out of 112 examined cows using ELISA, 3.6% were seropositive to L. interrogans serovar Hardjo infection. Seroconversion occurred in 5 animals (1 herd) of all examined animals in convalescent phase testing (5/112, 4.5%). Affected herd suffered acute outbreak with 43.3% within herd prevalence; signs of infection included abortions, bloody urine and sudden death of 2 cows. Highest risk for L. interrogans serovar Hardjo infection in cows was in animals drank from untreated surface water (6.7 times, p = 0.06). The seroprevalence of leptospirosis was 6.2% in all tested humans, 28.6% in nonspecific fever cases and 22.2% in non-viral hepatitis cases. The risk of leptospirosis among patients with nonspecific fever or non-viral hepatitis cases was 4 times higher than those with viral hepatitis (p = 0.01). Additionally, there was a significant association between leptospirosis and patients with livestock contact (Odds 8, p = 0.01). Conclusions: This is the first report of L. interrogans serovar Hardjo outbreak in cows in Egypt. The study also highlighted the role of leptospirosis as neglected cause of nonspecific fever/non-viral hepatitis in humans in study region.

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PRRSV: Risikofaktoren und Herdenprävalenz in Deutschland

Tierärztliche Praxis Ausgabe G Großtiere / Nutztiere ◽

10.1055/a-0867-8990 ◽

2019 ◽

Vol 47 (02) ◽

pp. 132-132

Author(s):

Sebastian Ganz

Keyword(s):

Risk Factors ◽

Cross Sectional Study ◽

Respiratory Syndrome Virus ◽

Sectional Study ◽

Cross Sectional ◽

Klinische Symptome

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.

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Associations of age-dependent IGF-1 standard deviation scores to cardiovascular diseases and risk factors: A cross-sectional study in 6,282 primary care patients

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-2007-972385 ◽

2007 ◽

Vol 115 (S 1) ◽

Author(s):

HJ Schneider ◽

J Klotsche ◽

H Lehnert ◽

C Sievers ◽

HU Wittchen ◽

...

Keyword(s):

Risk Factors ◽

Primary Care ◽

Standard Deviation ◽

Cardiovascular Diseases ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Age Dependent ◽

Primary Care Patients

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Role of Sildenafil in the Treatment of Persistent Pulmonary Hypertension of Newborn (PPHN) - Should it Be Withdrawn from Market of Bangladesh due to Threat of being Misuses

Dhaka Shishu (Children) Hospital Journal ◽

10.3329/dshj.v35i2.49688 ◽

2020 ◽

Vol 35 (2) ◽

pp. 100-104

Author(s):

Maksudur Rahman ◽

Mohammad Abdullah Al Mamun ◽

MAK Azad Chowdhury ◽

Abu Sayeed Munsi

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care ◽

Cross Sectional Study ◽

Sectional Study ◽

Cardiac Intensive Care Unit ◽

Cross Sectional ◽

Cardiac Intensive Care ◽

Hospital Protocol

Background: Recently it has been apprehended that sildenafil, a drug which has been successfully using in the treatment of PPHN and erectile dysfunction in adult, is going to be withdrawn from the market of Bangladesh due to threat of its misuses. Objective: The aim of this study was to see the extent of uses of sildenafil in the treatment of PPHN and importance of availability of this drugs in the market inspite of its probable misuses. Methods: This cross sectional study was conducted in neonatal intensive care unit (NICU), special baby care unit (SCABU) and cardiac intensive care unit (CICU) of Dhaka Shishu (Children) Hospital from June, 2017 to May 2018. Neonates with PPHN were enrolled in the study. All cases were treated with oral sildenefil for PPHN along with others management according to hospital protocol. Data along with other parameters were collected and analyzed. Results: Total 320 patients with suspected PPHN were admitted during the study period. Among them 92 (29%) cases had PPHN. Male were 49(53 %) cases and female were 43(47%) cases. Mean age at hospital admission was 29.7±13.4 hours. Based on echocardiography,13(14%) cases had mild, 38 (41%) cases moderate and 41(45%) cases severe PPHN. Mean duration of sildenafil therapy was 11.9±7.1 days. Improved from PPHN were 83 (90%) cases. Mortality was 10% (9). Conclusion: In this study it was found that the incidence of PPHN is 29% among the suspected newborns. Sildenafil is successfull in improving the oxygenation of PPHN and to decrease the mortality of neonates. DS (Child) H J 2019; 35(2) : 100-104

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