scholarly journals A single-centre investigator-blinded randomised parallel group clinical trial to investigate the effect of probiotic strainsStreptococcus salivariusM18 andLactobacillus acidophiluson gingival health of paediatric patients undergoing treatment with fixed orthodontic appliances: study protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e030638 ◽  
Author(s):  
Eleftherios G Kaklamanos ◽  
Rania Nassar ◽  
Sotirios Kalfas ◽  
Manal Al Halabi ◽  
Mawlood Kowash ◽  
...  

BackgroundThere is limited data on the beneficial effects of probiotics on the gingival health of patients undergoing treatment with fixed orthodontic appliances. This study aims to compare the effect of probiotic tablets combined with regular oral hygiene versus regular oral hygiene alone on gingival status in these patients. The effect of probiotic intake on plaque formation and salivary microbiome composition will be also assessed.Methods and analysisThis is a 3 month single-centre, single blind (clinical and laboratory examiners), parallel group randomised controlled two arm superiority trial. Fifty paediatric patients attending the Postgraduate Orthodontic Clinic at the Hamdan Bin Mohammed College of Dental Medicine (HBMCDM), Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, United Arab Emirates, who meet the eligibility criteria will be recruited. Block randomisation with 1:1 allocation and concealment of allocation will be carried out. The treatment group will receive probiotic tablets containingStreptococcus salivariusM18 andLactobacillus acidophilustogether with regular oral hygiene versus the control group on regular oral hygiene alone. Clinical examination and collection of saliva for microbiome assay will be carried out at baseline and end of study. Self-reporting by patients will be used to document acceptability and adverse effects. Statistically significant decrease in gingival bleeding on probing in the treatment group will be classified as primary outcome of treatment success. Statistically significant reduction in Plaque Index, Gingival Index and shift in the composition of the oral microbiome in favour of beneficial bacteria are secondary outcomes indicative of efficacy of probiotic intake.Ethics and disseminationEthical approval for the study has been granted by the HBMCDM, MBRU, Institutional Review Board (Reference #: MBRU-IRB-2018–015). Study findings will be disseminated via publication in peer-reviewed journal.Trial registration numberISRCTN95085398

2010 ◽  
Vol 57 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Sava Matic ◽  
Mirjana Ivanovic ◽  
Predrag Nikolic

Introduction. During orthodontic treatment, there is increased risk of periodontal disease and caries. Therefore these patients must be trained to maintain proper oral hygiene to minimize risks. The aim of this study was to examine the effects of oral hygiene training with different devices as well as a motivation and remotivation in oral hygiene using brochures, verbal methods and tablets for plaque identification. Material and Methods. The study included 80 subjects, both genders, divided in control (20) and experimental groups (60). All examinees in the experimental groups used toothbrush Curaprox CP5460 for oral hygiene. Subjects in experimental group 1 used mouthwash Curasept ADS 205, in the experimental group 2 orthodontic toothbrush CD Ortho 60 and proximal toothbrush Curaprox CPS14 while subjects in experimental group 3 used proximal toothbrush Curaprox CPS14 and mouthwash Curasept ADS 205. All participants were given tablets erythrosine and brochure in which was explained and illustrated the use of the aforementioned means for oral hygiene. Control check ups were conducted at the beginning, after the first, third and sixth month of the preventive program. Results. The values of the examined parameters, plaque index (PI), gingival index (GI) and gingival bleeding index (GBI), in experimental groups were significantly lower compared to control group (p<0.05). Conclusion. Motivation, compliance and implementation of all preventive procedures proposed by this program, as well as regular controls, contributed in maintaining gingival health during orthodontic treatment.


2021 ◽  
Vol 10 (23) ◽  
pp. 5638
Author(s):  
Urszula Kozak ◽  
Agnieszka Lasota ◽  
Renata Chałas

Good oral hygiene is an important factor in oral and general health, especially in orthodontic patients, because fixed appliances might impede effective oral hygiene and thus increase the risks of tooth decay, periodontal disease and general health complications. This study investigated the impact of fixed orthodontic appliances on the distribution of dental biofilm in teenagers. Supragingival plaque was assessed at T0, T1 and T2. The distribution of the biofilm was analyzed. Approximal Plaque Index (API) and Bonded Bracket Index (BBI) were used to measure the presence of dental plaque. After insertion of the fixed appliance, the dental plaque indices values in the orthodontically treated group were significantly higher (p < 0.05) than in the control group. Fixed orthodontic appliances caused significant changes in the distribution of the biofilm. This was characterized by the change of location of the dental plaque. In the orthodontic group, we observed an increase in the amount of the supragingival plaque on the vestibular surface of the teeth.


Author(s):  
Urszula Kozak ◽  
Anna Sękowska ◽  
Renata Chałas

The present study aimed to evaluate the effect of the oral-hygiene regime on the incidence of enamel demineralization in young patients treated with fixed appliances. Research was conducted in a group of 144 patients aged 12–18 years, divided into 2 groups: orthodontically treated and control. The study was divided into three stages: before treatment (I), at 1 month (II), and at 6 months (III) for their follow-up. The International Caries Detection and Assessment System (ICDAS) was used for the visual assessment of white spot lesions (WSL). After 1 month, no new white spot lesions were observed. After 6 months of the treatment, new lesions were observed in 5% of the orthodontically treated patients and in 6% of the patients in the control group. New decalcifications were located on the proximal surfaces of the central incisors, first premolars, and first molars in the orthodontically treated group; and on the lateral incisors, first premolars, and first molars in the control group. We also observed new enamel demineralization on the vestibular surfaces of the canine and first premolar in the study group. The placement of a fixed appliance did not significantly affect teeth with the presence of new white spot lesions compared to the control group during 6 months of observation.


2011 ◽  
Vol 68 (3) ◽  
pp. 214-219 ◽  
Author(s):  
Sava Matic ◽  
Mirjana Ivanovic ◽  
Predrag Nikolic

Background/Aim. Orthodontic treatment enables the establishment of functional occlusion and improvement of oral health, however, it increases the risk of periodontal disease development. The aim of this paper was to examine the efficiency of the applied programme for the prevention of gingivitis in children undergoing the fixed orthodontic appliance therapy and to determine the most efficient devices and techniques for maintaining oral hygiene during orthodontic treatment. Methods. The study included 80 patients of both genders - 60 patients comprised the experimental group and 20 patients comprised the control group. All of them were patients of the Clinic for Orthodontics at the School of Dentistry in Belgrade, aged between 13 and 18. The Silness-L?e Plaque Index (PI) was utilised for the assessment of oral hygiene quality and Silness-L?e Gingival Index (GI) and M?hlemann Papilla Bleeding Index (PBI) were utilised for the assessment of gingival state. Checkups were conducted as a single-blind study at the beginning and after the first, the third and the sixth month of the preventive and prophylactic programme. Results. During the observed period, a statistically significant change in PI, GI and PBI values was noticed (p < 0.005), as well as the difference in the dynamics of value changes during the periods between the observed groups. Conclusion. The preventive programme, applied to children undergoing the fixed orthodontic appliance therapy, had a positive effect both on oral hygiene quality and gingival state. The values of the examined parameters of the patients from the experimental group were significantly lower in comparison with those of the patients from the control group. The most efficient combination of devices for oral hygiene during orthodontic treatment was: a Curaprox CP5460 toothbrush, CD Ortho 60 orthodontic toothbrush and Curaprox CPS 14 interdental brush.


2016 ◽  
Vol 17 (3) ◽  
pp. 179-183 ◽  
Author(s):  
Brita Willershausen ◽  
Adriano Azaripour ◽  
Ines Willershausen ◽  
Muhamed Hassan ◽  
Supriya Ebenezer

ABSTRACT Objectives Fixed orthodontic appliances (FOAs) may cause a temporary deterioration of oral hygiene with corresponding gingival inflammatory changes. Optimal oral hygiene and dietary changes are essential in order to avoid periodontal inflammation. The present study investigates to what extent the recommendations made by the orthodontist are followed by young patients. Materials and methods A total of 67 adolescent patients with FOA were examined and interviewed. The control group consisted of 70 patients of the same age who had not undergone any orthodontic treatment. A specific questionnaire (assessing dietary habits, oral hygiene measures) was used and comprehensive oral findings along with oral hygiene status were evaluated. Results The analysis of the data showed that despite intensive oral hygiene and dietary advice in the patients with FOA, there was no change in diet or oral hygiene habits. There were significantly higher signs of gingival inflammation and amount of dental plaque in FOA patients. Nutritional recommendations and oral hygiene measures for young people with FOA were not adequately enforced. Conclusion The findings indicate that frequent recalls should be scheduled with repeated reinforcement of oral hygiene and dietary modifications in FOA patients. How to cite this article Azaripour A, Willershausen I, Hassan M, Ebenezer S, Willershausen B. Oral hygiene and dietary Habits in Adolescents with fixed orthodontic Appliances: A crosssectional Study. J Contemp Dent Pract 2016;17(3):179-183.


2008 ◽  
Vol 55 (2) ◽  
pp. 122-132 ◽  
Author(s):  
Sava Matic ◽  
Mirjana Ivanovic ◽  
Jelena Mandic ◽  
Predrag Nikolic

Introduction: During orthodontic treatment, the risk of gingivitis, periodontal disease and dental caries is increased. For good gingival health during orthodontic therapy, patients must be educated about the importance of daily oral hygiene and also given instructions on plaquecontrol techniques and how to use plaque removal devices properly. Objectives: The aim of this study was to present risk factors for gingivitis during treatment with fixed orthodontic appliances as well as methods and resources for prevention of this widespread disease. Conclusion: Maintaining proper oral hygiene is of great benefit not only for gingival health but also for the success of orthodontic treatment and maintenance of treatment results. Beside healthy gingiva, favorable habits in oral hygiene remain life-long.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Isamu Kado ◽  
Junzo Hisatsune ◽  
Keiko Tsuruda ◽  
Kotaro Tanimoto ◽  
Motoyuki Sugai

AbstractFixed orthodontic appliances are common and effective tools to treat malocclusion. Adverse effects of these appliances, such as dental caries and periodontitis, may be associated with alteration of the microbiome. This study investigated the impact of these appliances on the dynamics of the oral microbiome. Seventy-one patients were selected. Supragingival plaque samples were collected before placement (T0) and six months after placement (T1). Saliva samples were collected at T0 and T1, and then when appliance removal (T2). Microbial DNA was analyzed by 16S rRNA meta-sequencing. The diversity analysis indicated dynamic changes in the structure of the oral microbiome. Taxonomic analysis at phylum level showed a significant increase in Bacteroidetes and Saccharibacteria (formally TM7) and decrease in Proteobacteria and Actinobacteria over time, in both plaque and saliva. Genus level analysis of relative abundance indicated a significant increase in anaerobic and facultative anaerobes in both plaque and saliva. Fixed orthodontic appliances induced measurable changes in the oral microbiome. This was characterized by an increase in relative abundance of obligate anaerobes, including periodontal pathogens. It can be concluded that this dysbiosis induced by fixed orthodontic appliances is likely to represent a transitional stage in the shift in microbiome from healthy to periodontitis.


2016 ◽  
Vol 5 (2) ◽  
pp. 113-117
Author(s):  
Sara Rayner ◽  
Trislyn Herrick ◽  
Christina Chiesa

ABSTRACT Aims The aim of this pilot study was to assess changes in gingival bleeding and biofilm accumulation in young adults undergoing oil-pulling treatment together with standardized oral hygiene practices, compared to a control group of patients that did not undergo oil pulling but maintained the standard oral hygiene practices outlined in the study. Materials and methods The experiment was designed as a randomized, two-way, single-blind, crossover with a 2-month washout period between two, 10-day experimental periods. A total of 28, randomly selected dental students who met the inclusion criteria were assessed for gingival bleeding and biofilm on six teeth before and after rinsing with sesame oil for 10 minutes per day, for a period of 10 days. The mean difference between the test and control group's reduction in scores was analyzed using the paired t-test. The level of significance was set at ? (alpha) = 0.05. Results There were no statistically significant differences on plaque biofilm accumulation and bleeding when compared with the control group. There was a higher reduction in gingival bleeding scores (albeit not statistically significant) among those who used sesame oil compared to those who did not. Conclusion Based on the current study, it appears that oil pulling for 10 minutes and for a period of 10 days using sesame oil has no significant benefit over brushing and flossing alone, on a sample of 28 dental students. How to cite this article Rayner S, Herrick T, Chiesa C, Hoover J, Karunanayake C. Efficacy of “Oil Pulling” on Gingival Health and Biofilm Accumulation in a Group of Young Adults: A Pilot Study. Int J Experiment Dent Sci 2016;5(2):113-117.


2021 ◽  
Author(s):  
Asep Arifin Senjaya ◽  
Ni Made Sirat ◽  
I Nyoman Wirata ◽  
Ni Ketut Ratmini

Dental healthcare is very important since dental and oral hygiene should be maintained. Statistics showed that more than 80% of children in developed and developing countries suffer from dental disease. This study aimed to see the safety of OHIS (Oral Hygiene Index Simplified) in primary school students who got and did not get little dentist cadre training in Bangli Regency in 2019. The study was done in an experimental design: pre and post-test with control design, which was conducted in August-September 2019. The sample in this study is 366 students. The difference in OHIS scores before and after treatment in the control group and treatment group was carried out by the bivariate Mann Whitney U Test. The results of the study showed that before dental health training was conducted, there were 54.3% of primary school students in the treatment group with good OHIS score criteria, and after the training was carried out as many as 98.4% of the students in the treatment group had a good OHIS. Additionally, prior to the training, 57.5% of the control group had fair OHIS criteria score. Then, after the training was carried out, 73.7% of the control group had good OHIS score. Hence, the study concluded that there was a significant difference in the OHIS of primary school students who got little doctor training prior to and after the training. Also, there was a significant difference in the OHIS of the students who did not get such treatment before and after the training.


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