scholarly journals Cross-sectional association between long working hours and liver function: the Kangbuk Samsung Health Study

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e041595
Author(s):  
Eunchan Mun ◽  
Woncheol Lee ◽  
Min-Woo Nam ◽  
Hyun-Il Kim ◽  
Hyeongcheol Kim ◽  
...  
Keyword(s):  
General Population ◽  
Hepatitis B ◽  
Liver Function ◽  
South Korea ◽  
Hepatitis B Surface Antigen ◽  
Working Hours ◽  
Health Study ◽  
Health Examination ◽  
Cross Sectional ◽  
Long Working Hours

ObjectivesAlthough the effects of long working hours on liver function remain unclear, in South Korea, there is a social perception that long working hours are associated with poor liver function. Thus, long working hours have recently become a major issue. This study aimed to determine the association between long working hours and liver function, as indicated by the alanine transaminase (ALT) levels.DesignCross-sectional study.SettingLarge university hospitals in Seoul and Suwon, South Korea.ParticipantsWorkers in formal employment who underwent a comprehensive health examination at the Kangbuk Samsung Hospital Total Healthcare Centre clinics in Seoul and Suwon, South Korea, between January 2011 and December 2018. Of the 386 488 participants, 212 421 met the inclusion criteria and were included in the analysis.Primary outcome measureALT elevation.ResultsThe participants were predominantly well-educated (86.1%), male (69.3%) and in their 30s (49.6%). In total, 13.4% of the participants presented ALT elevation (>40 IU/L). There was no significant association between working hours and ALT elevation in the general population and in the hepatitis B surface antigen (HBsAg)-negative group. Conversely, in the HBsAg-positive group, working >60 hours per week compared with 35–40 hours per week was significantly associated with ALT elevation. The association was more pronounced in those with ALT levels >80 IU/L (OR 1.94, 95% CI 1.24 to 3.01) than in those with ALT levels >40 IU/L (OR: 1.45, 95% CI 1.20 to 1.75). The p values for trend were <0.05.ConclusionsLong working hours were associated with ALT elevation only in hepatitis B virus carriers and not in the general population. Provided that there is adherence to the legal working hours, there is no need to further restrict working hours for liver health, irrespective of HBsAg status.

scholarly journals Cross-sectional association between long working hours and endoscopic gastritis: the Kangbuk Samsung Health Study

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e050037
Author(s):  
Eunchan Mun ◽  
Yesung Lee ◽  
Woncheol Lee ◽  
Soyoung Park
Keyword(s):  
South Korea ◽  
Atrophic Gastritis ◽  
Intestinal Metaplasia ◽  
Working Hours ◽  
Health Examination ◽  
Full Time ◽  
Erosive Gastritis ◽  
Cross Sectional ◽  
Long Working Hours ◽  
Superficial Gastritis

ObjectivesThis study aimed to determine the cross-sectional association between long working hours and gastritis diagnosed by endoscopy.DesignCross-sectional study.SettingLarge university hospitals in Seoul and Suwon, South Korea.ParticipantsWorkers in formal employment who underwent a comprehensive health examination at the Kangbuk Samsung Hospital Total Healthcare Centre clinics in Seoul and Suwon, South Korea, between January 2011 and December 2018. Of the 386 488 participants, 168 391 full-time day workers met the inclusion criteria and were included in the analysis.Primary outcome measureEndoscopic gastritis.ResultsThe participants were predominantly college graduates or above (88.9%), male (71.2%) and in their 30s (51.1%), and the median age was 36 (IQR 31–42). Approximately 93.2% of participants had positive endoscopic gastritis, and there was a significant association between working hours and positive findings of endoscopic gastritis. The multivariate fully adjusted prevalence ratio (PR) of endoscopic gastritis for participants working >55 hours per week compared with 35–40 hours per week was 1.011 (95% CI 1.007 to 1.015). Furthermore, endoscopic findings were classified into nine subtypes of gastritis, including superficial gastritis, erosive gastritis, atrophic gastritis, intestinal metaplasia and haemorrhagic gastritis increased with longer working hours (p for trends <0.05). Their PRs for participants working >55 hours per week compared with 35–40 hours per week were 1.019 (95% CI 1.012 to 1.026), 1.025 (95% CI 1.011 to 1.040), 1.017 (95% CI 1.008 to 1.027), 1.066 (95% CI 1.028 to 1.105) and 1.177 (95% CI 1.007 to 1.375), respectively.ConclusionsWorking over 55 hours per week was cross-sectionally associated with positive findings of endoscopic gastritis. The study findings indicated potentially increased risks of superficial gastritis, erosive gastritis, atrophic gastritis, intestinal metaplasia and haemorrhagic gastritis among workers with long working hours (>55 hours per week), supporting the need for further exploration via longitudinal studies.

scholarly journals Assessment of knowledge, attitude, and practices toward prevention of hepatitis B infection among medical students in a high-risk setting of a newly established medical institution

2018 ◽  
Vol 10 (04) ◽  
pp. 374-379 ◽  
Author(s):  
Akanksha Rathi ◽  
Vikas Kumar ◽  
Jitendra Majhi ◽  
Shalini Jain ◽  
Panna Lal ◽  
...  
Keyword(s):  
Medical Students ◽  
High Risk ◽  
General Population ◽  
Hepatitis B ◽  
Hepatitis B Surface Antigen ◽  
Pearson Correlation ◽  
Knowledge Score ◽  
Medical Institution ◽  
Hepatitis B Vaccination ◽  
Cross Sectional

ABSTRACT BACKGROUND: India is in the intermediate hepatitis B virus endemicity zone with hepatitis B surface antigen prevalence among the general population ranges from 2% to 8%. Among health-care workers, seroprevalence is two to four times higher than that of the general population. AIM: The aim of the study was done to assess the knowledge, attitude, and practices (KAPs) of medical students regarding hepatitis B. MATERIALS AND METHODS: This is a cross-sectional study that was conducted from March to April 2018. Students were invited to the department on specified dates for awareness and immunization against hepatitis B. Their KAP was assessed with the help of a self-administered questionnaire. RESULTS: With a response rate of 81.3%, a total of 161 students participated in the study out of 198. Out of the 161 study participants, only 13 (8%) students had received a completed course of hepatitis B vaccination in the past, 30 (18.7%) students had a history of inability to complete the three doses of hepatitis B vaccination, and the rest 118 (73.3%) students were never immunized against hepatitis B. The knowledge about the risk of acquiring the disease at the hospital or high-risk setting was present in less than half of the students. The average knowledge score was 10.63 out of 16 and average healthy practice score was 2.94 out of 4. On applying Pearson correlation test, it was found that there was a positive correlation of knowledge and practices of the students (P = 0.012), implying that better knowledge of the disease has a positive effect on the practices exercised by an individual. CONCLUSION: Newly enrolled students and other individuals attached to a high-risk setting such as a medical institution should be screened for immunization status during initial medical examination as the number of unimmunized persons, especially against hepatitis B is high.

scholarly journals Parental long working hours and adult children's depression in South Korea: a cross-sectional study

2020 ◽  
Author(s):  
Hyunil Kim ◽  
Woncheol Lee ◽  
Soyoung Park ◽  
Hyeongcheol Kim
Keyword(s):  
South Korea ◽  
Adult Children ◽  
Working Hours ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Long Working Hours ◽  
Children’S Depression ◽  
Patient Health ◽  
Family Based

Abstract Background: This study investigated the association between parental long working hours and the depression of adult children living with them in South Korea. Methods: Data from two years of the Korean National Health and Nutrition Examination Survey (KNHANES) in 2014 and 2016 were analyzed using a cross-sectional study. Study samples included 1334 adult children aged ≥ 19 and 2486 parents (1483 mothers and 1003 fathers). Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analyses were performed to determine the association between parental long working hours and their adult children’s depression. Results: Odds ratio (OR) of adult children’s depression for maternal working > 60 hours/week was 4.88 (95% confidential interval (CI): 1.95 – 12.2) when maternal working ≤ 40 hours/week was considered as a reference in the crude model. After considering parental and adult children’s socio-demographic characteristics and occupational characteristics, and parental depression, OR of adult children’s depression for maternal working was found to be 10.2 (95% CI: 2.47 – 42.0). The association between paternal long working hours and adult children’s depression was not statistically significant. Conclusions: Mothers’ long working hours were associated with the greater risk of their adult children’s depression in South Korea. Comprehending aging mothers’ weekly working hours is an important factor when developing strategies for addressing adult children’s depression using family-based interventions.

scholarly journals The Impact of Universal Infant Hepatitis B Immunization on Reducing the Hepatitis B Carrier Rate in Pregnant Women

2018 ◽  
Vol 220 (7) ◽  
pp. 1118-1126 ◽  
Author(s):  
Wei-Ju Su ◽  
Shu-Fong Chen ◽  
Chin-Hui Yang ◽  
Pei-Hung Chuang ◽  
Hsiu-Fang Chang ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Pregnant Women ◽  
Screening Program ◽  
Hepatitis B Surface Antigen ◽  
Carrier Rate ◽  
Cross Sectional ◽  
Hbv Vaccine ◽  
Hbv Vaccination ◽  
The Impact ◽  
Universal Infant

Abstract Background The hepatitis B virus (HBV) status of pregnant women affects HBV vaccine failure in their offspring. This study is aimed to investigate the impact of the universal infant HBV vaccination program on the long-term hepatitis B surface antigen (HBsAg) rate in pregnant women. Methods Using the National Immunization Information System, we examined a 32-year period of cross-sectional data on a maternal HBsAg and hepatitis B e antigen (HBeAg) screening program launched in July 1984. An age-period-cohort model analysis of 940 180 pregnant women screened for July 1996–June 1997 and the years 2001, 2006, 2011, and 2016 was applied. Results The annual HBsAg- and HBeAg-seropositive rates decreased from 13.4% and 6.4%, respectively, for the period 1984–1985 to 5.9% and 1.0% in 2016 (P for both trends < .0001). Pregnant women with birth years after July 1986 (the HBV vaccination cohort) had the lowest relative risk (0.27 [95% confidence interval, .26–.28]) of HBsAg positivity compared with birth years before June 1984. Conclusions The birth cohort effect in relation to the universal infant HBV immunization program has effectively reduced the HBV carrier rate in pregnant women and the burden of perinatal HBV infection on the next generation.

scholarly journals Seroprevalence and Knowledge of Viral Hepatitis and HIV Among People Who Use Drugs Attending Methadone Therapy Clinic in Tanzania: A Cross-sectional Study.

2020 ◽  
Author(s):  
Semvua Kilonzo ◽  
Daniel W. Gunda ◽  
David C. Majinge ◽  
Hyasinta Jaka ◽  
Paulina M. Manyiri ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Hepatitis B Surface Antigen ◽  
People Who Use Drugs ◽  
Infection Rates ◽  
Cross Sectional ◽  
B Virus

Abstract Background: Methadone therapy clinics have been recently introduced in Tanzania, aiming at reducing risk behaviors and infection rates of viral hepatitis and HIV among people who use drugs. The objective of this study was to estimate the prevalence, associated factors and knowledge level of these conditions among people who use drugs attending a methadone clinic in Tanzania.Methods: We enrolled 253 People who using drugs receiving Methadone therapy. Clinical data was retrospectively collected from the medical records and face-to face interviews were conducted to determine the behavioral risk factors and respondents’ knowledge on viral hepatitis and HIV.Results: An overall seroprevalence of viral hepatitis (either hepatitis B surface antigen or anti-hepatitis C virus) was 6.3%, while that of hepatitis B virus mono infection was 3.5% and anti-hepatitis C virus mono infection was 3.5%. Seroprevalence of HIV was 12.6%. Viral hepatitis was strongly predicted by advanced age (>35 years) (p=0.02) and staying at Kirumba area (p=0.004), and HIV infection was predicted by increased age (>37 years) (p=0.04) and female sex (p<0.001). Regarding the knowledge of viral hepatitis, majority of the respondents were unaware of the transmission methods and availability of hepatitis B virus vaccines and only 17% were classified as well informed (provided ≥ 4 correct answers out of 7 questions). Good knowledge was highly predicted by higher education level of the individual (p=0.001).Conclusions: Despite the efforts to curb viral hepatitis and HIV infections through Methadone clinics, infection rates among people who use drugs are still high and the general knowledge on preventive measures is inadequate.

scholarly journals Working hours and health in nurses of public hospitals according to gender

2017 ◽  
Vol 51 (0) ◽  
Author(s):  
Juliana da Costa Fernandes ◽  
Luciana Fernandes Portela ◽  
Rosane Härter Griep ◽  
Lúcia Rotenberg
Keyword(s):  
Rio De Janeiro ◽  
Reference Group ◽  
Working Hours ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Cross Sectional ◽  
Long Working Hours ◽  
Self Rated Health ◽  
Janeiro State

ABSTRACT OBJECTIVE To assess the association between weekly working hours and self-rated health of nurses in public hospitals in Rio de Janeiro, State of Rio de Janeiro, Brazil. METHODS A total of 3,229 nurses (82.7% of the eligible group) participated in this cross-sectional study, carried out between April 2010 and December 2011. The collection instrument consisted of a self-administered multidimensional questionnaire. The weekly working hours were calculated from a recall of the daily hours worked over seven consecutive days; this variable was categorized according to tertiles of distribution for men and women. The outcome of interest, self-rated health, was categorized into three levels: good (very good and good), regular, and poor (poor and very poor). The statistical analysis of the data included bivariate and multivariate analyses, having as reference group those with short working hours (first tertile). All the analyses were stratified by gender and elaborated using the program SPSS. RESULTS Among women, the group corresponding to the longest working week (more than 60.5 hours per week) were more likely to report regular self-rated health, compared with those with shorter working hours, after adjusting for confounding factors (OR = 1.30; 95%CI 1.02–1.67). Among men, those with average working hours (49.5–70.5 hours per week) were more than twice as likely to rate their health as regular (OR = 2.17; 95%CI 1.08–4.35) compared to those with shorter working hours (up to 49.5 hours). There was no significant association between long working hours and poor self-rated health. CONCLUSIONS The results point to the urgent need to promote interventions in the organization of work and appreciation of the nursing profession, in order to reduce the number of multiple jobs and thus contribute to mitigate potential effects on the health of workers and the quality of care in hospitals.

scholarly journals Influence of trust on two different risk perceptions as an affective and cognitive dimension during Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea: serial cross-sectional surveys

BMJ Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. e033026 ◽  
Author(s):  
Won Mo Jang ◽  
Un-Na Kim ◽  
Deok Hyun Jang ◽  
Hyemin Jung ◽  
Sanghyun Cho ◽  
...  
Keyword(s):  
Risk Perception ◽  
Middle East ◽  
General Population ◽  
South Korea ◽  
Risk Perceptions ◽  
Economic Status ◽  
Cross Sectional ◽  
Cognitive Risk ◽  
Household Economic Status ◽  
The Government

ObjectivesThis study aimed to assess the affective and cognitive risk perceptions in the general population of Middle East respiratory syndrome (MERS) during the 2015 MERS coronavirus (MERS-CoV) outbreak in South Korea and the influencing factors.DesignSerial cross-sectional design with four consecutive surveys.SettingNationwide general population in South Korea.ParticipantsOverall 4010 respondents (aged 19 years and over) from the general population during the MERS-CoV epidemic were included.Primary and secondary outcome measuresThe main outcome measures were (1) affective risk perception, (2) cognitive risk perception, and (3) trust in the government. Multivariate logistic regression models were used to identify factors (demographic, socioeconomic, area and political orientation) associated with risk perceptions.ResultsBoth affective and cognitive risk perceptions decreased as the MERS-CoV epidemic progressed. Proportions of affective risk perception were higher in all surveys and slowly decreased compared with cognitive risk perception over time. Females (adjusted OR (aOR) 1.72–2.00; 95% CI 1.14 to 2.86) and lower self-reported household economic status respondents were more likely to perceive the affective risk. The older the adults, the higher the affective risk perception, but the lower the cognitive risk perception compared with younger adults. The respondents who had low trust in the government had higher affective (aOR 2.19–3.11; 95 CI 1.44 to 4.67) and cognitive (aOR 3.55–5.41; 95 CI 1.44 to 9.01) risk perceptions.ConclusionsThis study suggests that even if cognitive risk perception is dissolved, affective risk perception can continue during MERS-CoV epidemic. Risk perception associating factors (ie, gender, age and self-reported household economic status) appear to be noticeably different between affective and cognitive dimensions. It also indicates that trust in the government influences affective risk perception and cognitive risk perception. There is a need for further efforts to understand the mechanism regarding the general public’s risk perception for effective risk communication.

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