scholarly journals Chronic breathlessness and sleep problems: a population-based survey

BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e046425
Author(s):  
David C Currow ◽  
Sungwon Chang ◽  
Diana Ferreira ◽  
Danny J Eckert ◽  
David Gonzalez-Chica ◽  
...  

ObjectivesThis study aimed to explore the relationship (presence and severity) between chronic breathlessness and sleep problems, independently of diagnoses and health service contact by surveying a large, representative sample of the general population.SettingAnalysis of the 2017 South Australian Health Omnibus Survey, an annual, cross-sectional, face-to-face, multistage, clustered area systematic sampling survey carried out in Spring 2017.Chronic breathlessness was self-reported using the ordinal modified Medical Research Council (mMRC; scores 0 (none) to 4 (housebound)) where breathlessness has been present for more than 3 of the previous 6 months. ‘Sleep problems—ever’ and ‘sleep problem—current’ were assessed dichotomously. Regression models were adjusted for age; sex and body mass index (BMI).Results2900 responses were available (mean age 48.2 years (SD=18.6); 51% were female; mean BMI 27. 1 (SD=5.9)). Prevalence was: 2.7% (n=78) sleep problems—past; 6.8% (n=198) sleep problems—current and breathlessness (mMRC 1–4) was 8.8% (n=254). Respondents with sleep problemspast were more likely to be breathless, older with a higher BMI and sleep problems—present also included a higher likelihood of being female.After adjusting for age, sex and BMI, respondents with chronic breathlessness had 1.9 (95% CI=1.0 to 3.5) times the odds of sleep problems—past and sleep problems—current (adjusted OR=2.3; 95% CI=1.6 to 3.3).ConclusionsThere is a strong association between the two prevalent conditions. Future work will seek to understand if there is a causal relationship using validated sleep assessment tools and whether better managing one condition improves the other.

2018 ◽  
Vol 43 (2) ◽  
pp. 63-70
Author(s):  
Dilip Kumar Ghosh ◽  
Chanchal Kumar Ghosh ◽  
Mukta Nath ◽  
Syed Alamgir Safwath ◽  
Santosh Kumar Saha ◽  
...  

The infection with the Hepatitis B virus (HBV) is a global health problem. Hepatitis B virus (HBV) infections are rapidly spreading in developing countries due to the lack of health education, poverty, illiteracy and Hepatitis B vaccination. No widespread population based data of HBV is available in the country's aspect. So, a population-based serological survey was done to determine the prevalence of the Hepatitis B core antibody total (IgM+IgG) in an impoverished Urban Community in Dhaka, Bangladesh. A descriptive cross-sectional study was conducted among 384 healthy individuals and age between 18-60 years from the urban slum in Dhaka city. The study was implemented through collaboration with Shaheed Suhrawardy Medical College, Dhaka from January 2013 to June 2013. The study participants were selected through systematic sampling procedure and blood tested for anti-HBc. Anti-HBc estimations were carried out by VITROS Immune diagnostic assay. The study was pertained Ethical permission from Bangladesh Medical Research Council (BMRC) and every participant was informed regarding their written informed consent. Among the 384 respondents, 183(47.6%) individuals were positive for the core antibody of hepatitis B virus (anti-HBc). The anti HBc positive group consisted almost of equal number of male 93, (24.2%) and female 90 (23.4%). There was a significantly increasing prevalence of the core antibody among young adults and middle age of the respondents (28.7%). Major risk factors for exposure to Hepatitis B appeared to be Ear-nose-body piercing, Circumcision by Hajam, unsafe blood transfusion and unsterile dental intervention. High prevalence of hepatitis B Core antibody (47.6%) indicates that the members of this urban community are highly exposed to hepatitis B virus.


2013 ◽  
Vol 29 (7) ◽  
pp. 1322-1332 ◽  
Author(s):  
Raquel de Macedo Bosco ◽  
Elisa Priscila Souza Assis ◽  
Renata Rosseti Pinheiro ◽  
Luiza Cristina Viana de Queiroz ◽  
Leani S. M. Pereira ◽  
...  

This study evaluated the association between anemia and physical functional capacity in a cross-sectional population-based sample of 709 hospitalized elderly patients aged 60 years and over admitted to the Madre Teresa Hospital, Belo Horizonte, State of Minas Gerais, Brazil. The Mann-Whitney or "t" test, and chi-square or Fisher exact test were used for quantitative and categorical variables, respectively, and hierarchical binary logistic regression was used to identify significant predictors. The presence of anemia was found in 30% of participants and was significantly associated with decreased functionality according to the two measures which were used - ADL (activities of daily living) and IADL (instrumental activities of daily living). Anemia was also independently associated with older age. The results of this study demonstrate a strong association between the presence of anemia and lower levels of functional capacity. Further investigations are needed to assess the impact of anemia treatment on the functionality and independence of older people.


2019 ◽  
Author(s):  
Getahun Gebre Bogale

Abstract Background: More than 35% of Ethiopian population is using drinking water from unimproved sources. As per the United Nations’ Sustainable Development Goals, Ethiopia is aspiring to achieve universal and equitable access to safe and affordable drinking water for all by 2030. For these goals to be accomplished, it is important to map the country’s hotspot areas of unimproved source of drinking-water so that resource allocation and disease control can be optimized there. Methods: A population based cross-sectional study was conducted in Ethiopia from January 18 to June 27, 2016. Data were collected from 10,064 households using a pretested and structured questionnaire. A stratified two-stage cluster sampling was employed where the enumeration areas were primary sampling units and households were secondary sampling units. Systematic sampling with probability proportional to size was employed to select samples. Data were cleaned in spreadsheet and entered in to SaTScan and ArcGIS soft-wares for mapping and analysis. The Global Moran’s I and spatial scan statistical tests (Bernoulli model) were done to explore the presence of clustering in the study area and local spatial clusters (hotspots) of unimproved sources of drinking water using ArcGIS version 10.3 and Kuldorff’s SaTScan version 9.4 soft-wares, respectively. Moran’s I value closer to +1 declared presence of clustering at national level and Log-Likelihood ratio (LLR) greater than the critical value with p<0.05 declared statistical significant hotspots across the regions. Results: In this study, unimproved sources of drinking water were spatially clustered at the study area (Moran’s I: 0.35, p<0.05). A total of 143 significant clusters were identified. Of which, eight were most likely (primary) clusters and the rest 135 were secondary clusters. The first spatial window which contains primary clusters was located in Amhara and Afar regions (LLR: 78.89, at p<0.001). The rest 33 spatial windows which contain secondary clusters were found in all regions, except Gambela region and Addis Abeba city administration (with a range of LLR: 10.09-78.89, p<0.001). Conclusions: This study identified non-random clusters and hot spots of unimproved sources of drinking water. Therefore, the result helps decision makers for their geographical interventions to combat problems related to hotspots.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Øyvind Helgeland ◽  
Jens K. Hertel ◽  
Anders Molven ◽  
Helge Ræder ◽  
Carl G. P. Platou ◽  
...  

Background.Two adjacent regions upstreamCDKN2Bon chromosome 9p21 have been associated with type 2 diabetes (T2D) and progression of cardiovascular disease (CVD). The precise location and number of risk variants have not been completely delineated and a possible synergistic relationship between the adjacent regions is not fully addressed. By a population based cross-sectional case-control design, we genotyped 18 SNPs upstream ofCDKN2Btagging 138 kb in and around two LD-blocks associated with CVD and T2D and investigated associations with T2D, angina pectoris (AP), myocardial infarction (MI), coronary heart disease (CHD; AP or AMI), and stroke using 5,564 subjects from HUNT2.Results.Single point and haplotype analysis showed evidence for only one common T2D risk haplotype (rs10757282∣rs10811661: OR = 1.19,P=2.0×10-3) in the region. We confirmed the strong association between SNPs in the 60 kb CVD region with AP, MI, and CHD(P<0.01). Conditioning on the lead SNPs in the region, we observed two suggestive independent single SNP association signals for MI,rs2065501  (P=0.03)andrs3217986  (P=0.04).Conclusions.We confirmed the association of known variants within the 9p21 interval with T2D and CHD. Our results further suggest that additional CHD susceptibility variants exist in this region.


2022 ◽  
pp. oemed-2021-107899
Author(s):  
Gabriela Schmajuk ◽  
Laura Trupin ◽  
Edward H Yelin ◽  
Paul D Blanc

ObjectivesWe previously showed increased coal mining-associated risk of rheumatoid arthritis (RA). Using additional survey data, we sought to delineate this risk further.MethodsWe used data from two cross-sectional, random-digit-dial, population-based surveys (males;≥50 years) in selected counties in the Appalachian region of the inland, mid-Atlantic USA with elevated pneumoconiosis mortality. Surveys ascertained age, smoking, coal mining and non-coal silica exposure jobs. In a subset, we surveyed ergonomic exposures, scored by intensity. We queried diagnosis of RA, corticosteroid use, and, in a subset, use of disease modifying antirheumatic drugs (DMARDs). Multivariable logistic regression modelled RA risk (defined by glucocorticoid or DMARDs use) associated with coal mining employment, other silica exposure, smoking status, and age and ergonomic exposures.ResultsWe analysed data for 2981 survey respondents (mean age 66.6 years; 15% current, 44% ex-smokers). The prevalence of glucocorticoid-treated and DMARD-treated RA was 11% and 4%, respectively. Glucocorticoid-treated RA was associated with coal mining (OR 3.5; 95% CI 2.5 to 4.9) and non-coal mining silica exposure (OR 3.2; 95% CI 2.4 to 4.4). For DMARD-treated RA, the odds associated with coal mining and other silica remained elevated: OR 2.3 (95% CI 1.18, 4.5) and OR 2.7 (95% CI 1.51, 5.0), respectively. In the same model, the highest intensity ergonomic exposure also was associated with increased odds of RA (OR 4.3; 95% CI 1.96 to 9.6).ConclusionsWe observed a strong association between coal mining and other silica-exposing dusty trades and RA. Clinicians and insurers should consider occupational histories in the aetiology of RA.


2005 ◽  
Vol 29 (4) ◽  
pp. 357-362 ◽  
Author(s):  
Ana Estela Haddad ◽  
Maria Salete Nahás Pires Correa

The objective of this study is to determine the correlation between the number of erupted primary teeth, the age, sex and the somatic measures of weight and height (length) in a Brazilian population based cross sectional study. A systematic sampling was used. Complete and consistent data were obtained from 870 of a total of 908 children from birth to 36 months of age. Statistical analysis comprised a multiple regression equation, where the number of erupted primary teeth was modeled as the dependent variable and the initial specification included the following independent variables: age, sex, birth-length, birth-weight, weight and length measured at the examination of the child. Results showed that in this study, 86% of the variation of the number of erupted primary teeth was explained by age and height of children (p&lt;0.001). Age and height showed a stronger correlation with the number of erupted primary teeth than all the tested variables together. It was concluded that primary teeth eruption is highly influenced by age and height (length) of the child. Using the best regression equation found, a chart was constructed where the variation of the number of erupted primary teeth is given according to age and height of the child.


2013 ◽  
Vol 50 (2) ◽  
pp. 117-122 ◽  
Author(s):  
David Timm KVITKO ◽  
Gisele Alsina Nader BASTOS ◽  
Maria Eugênia Bresolin PINTO

Context The hepatitis C is a severe public health problem worldwide because its consequences. Studies which aim at determining the prevalence of risk factors are really important to understand the problem. Objective To estimate the prevalence and factors associated with some risk factors for the disease in a community, called Restinga, located in the city of Porto Alegre, RS, Brazil. Method This paper is based on a population-based cross-sectional study, with systematic sampling and proportional to the size of census tracts in which 3,391 adults answered a standardized questionnaire. Results The prevalence of blood transfusion among the people who were interviewed was 14.98%, 60.83% of those had it before 1993. A total of 16.16% of the people had a tattoo, 7.23% wore a piercing, 1.09% said they had already injected illicit drugs and 12.39% reported previous hospitalization. Prevalence ratios showed that tattoos were more common among young people, piercings among women and illicit drugs among men. Conclusions To summarize, the recognition of risk factors for hepatitis C enables proper screening of possible carriers of the hepatitis C virus, thus enabling a reduction in virus shedding. However, being only possible if health services are prepared to deal with hepatitis C virus, through education and public awareness.


2020 ◽  
Author(s):  
Jianhao Lin ◽  
Qing Xi Zhang ◽  
Qiang Liu ◽  
Chu Tong Lin ◽  
Yangjin Baima ◽  
...  

Abstract Objective There has been no epidemiological survey of it in Tibet. We estimated the prevalence of rheumatoid arthritis in Luoma Town, Naqu City, Tibet Autonomous Region of China. Methods A population-based cross-sectional survey was conducted among 1458 residents of Luoma Town, Tibet Autonomous Region, aged ≥ 40 years. We used questionnaires in face-to-face interviews, anthropometric measurements and rheumatoid factor (RF), autoantibodies binding to citrullinated antigens (ACPA) and C-reactive protein (CRP) test. The definition of rheumatoid arthritis in this study was on the basis of new 2010 ACR/EULAR classification criteria. Results 782 participants completed all items of rheumatoid arthritis. The overall crude prevalence of rheumatoid arthritis was 4.86%. The prevalence was higher in women than in men (7.14% vs. 2.56%, P = 0.005). Tibetan had a higher age-standardized prevalence of rheumatoid arthritis 6.30% (95% confidence interval: 4.20% − 8.64%) compared with the other areas in China (range: 0.20% − 0.93%). Conclusion The prevalence of rheumatoid arthritis is relatively higher than other places in China.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shiva Raj Acharya ◽  
B. K. Suman ◽  
Sandip Pahari ◽  
Yong Chul Shin ◽  
Deog Hwan Moon

Abstract Background Elder abuse is recognized as a serious public health concern and top priority aging issues. World Health Organization reported that around 1 out of 6 old people in the world experienced some form of abuse. This study was carried out to find out the prevalence of different forms of abuse among elderly Nepalese people. Methods The cross-sectional, quantitative analytical study was carried out among 373 elders of the Syangja district of Nepal. The study population was selected through simple, proportionate, and systematic sampling methods. Data was collected through face-to-face interviews using a structured questionnaire. Results The majority of participants were female (54.5%). The prevalence of elderly abuse was found to be 54.5%. The most common form of abuse among the elderly population was neglect (23.1%), psychological abuse (20.6%), physical abuse (6.5%), financial abuse (2.4%), and sexual abuse (1.9%). Elderly females were significantly more likely to experience physical and psychological abuse. Conclusion More than half of the elderly experienced at least one form of abuse. Neglect was found to be the most common form of abuse. The abuse was prevalent among elderly who were ill and with the habit of tobacco and alcohol consumption.


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