scholarly journals Schizophrenia with and without obsessive-compulsive symptoms: a comparative analysis of performance on trail making test and disability on WHODAS

2020 ◽  
Vol 33 (6) ◽  
pp. e100237
Author(s):  
Apala Singh ◽  
Ram Pratap Beniwal ◽  
Triptish Bhatia ◽  
Smita Neelkanth Deshpande

BackgroundPresence of obsessive-compulsive symptoms (OCS) affects performance on tests of some cognitive functions, such as the trail making test (TMT), and may affect the level of disability in schizophrenia (SZ).AimsThe aim of the present study was to compare performance on TMT and disability on WHO Disability Assessment Schedule (WHODAS) in persons with SZ with and without OCS in a cross-sectional study.MethodsPersons with SZ (n=200) fulfilling DSM-V (Diagnostic and Statistical Manual) diagnostic criteria were assessed on Yale Brown Obsessive Compulsive Scale (YBOCS) and divided into two groups based on presence or absence of OCS. TMT and WHODAS V.2.0 were applied. The two groups as a whole, as well as a subsample matched on age, gender and age of onset were compared.ResultsOut of 200 persons with SZ, 37 (18.5%) reported OCS. The OCS group took a significantly longer mean time to complete TMT-A (Z=−3.02, p=0.003) as well as TMT-B (Z=-3.551, p<0.001). Significant correlations were found between TMT-A and total YBOCS Scores (r=0.351, p=0.033), as well as TMT-A and YBOCS compulsion scores (r=0.404, p=0.013) but not with TMT-B Scores. The OCS group reported greater disability in all domains separately as well as on average WHODAS Scores (Z=−5.969, p<0.001). Significant correlations were found between YBOCS obsession scores and YBOCS total scores with average WHODAS Scores (r=0.614, p<0.001 and r=0.406, p=0.013, respectively). We obtained essentially similar results with the matched subsample as well as with the entire group.ConclusionPersons with SZ and comorbid OCS had significantly poorer performance on TMTs and greater disability in comparison to persons with SZ alone. Magnitude of disability correlated with severity of OCS.

2020 ◽  
Vol 8 (3) ◽  
pp. 233-242
Author(s):  
Shima Pajouhinia ◽  
◽  
Yalda Abavisani ◽  
Zahra Rezazadeh ◽  
◽  
...  

Objective: Cognitive flexibility and social cognition are the appropriate models for understanding psychological problems, through which people can meet various challenges. The aim of this study was to investigate the relationship between cognitive flexibility and social cognition with obsessive-compulsive symptoms among female students at Allameh Tabataba’i University. Methods: This cross-sectional study was done on 200 students female students at Allameh Tabataba’i University in Tehran studying in the academic year 2018-2019 selected by random multiple cluster sampling method. The used tools were cognitive flexibility inventory, student social cognition questionnaire, and obsessive-compulsive symptoms inventory. Results: There was a negative significant correlation between the total score of obsessive-compulsive symptoms with cognitive flexibility and social cognition. In addition, the results of multiple regression analysis showed that cognitive flexibility and social cognition can explain obsessive-compulsive symptoms in students. Conclusion: Studying cognitive flexibility and social cognition is an efficient method to understand the underlying factors associated with obsessive-compulsive symptoms. Evaluation of these factors can be useful in the prevention and treatment of these symptoms.


2021 ◽  
pp. 1-3
Author(s):  
Rakesh. B. Shitole ◽  
Hiral Thakkar

Background- Increased responsibility and high demands of studying at medical school can also be associate with Obsessive Compulsive symptoms in general so they need to be mindful all the time to grasp knowledge and handle responsibility so that this study was to correlate and analyse mindfulness among OT UG along with their OCD symptoms. Aim-To study the correlation between obsessive compulsive symptoms & mindfulness among OT UG. Objectives - Measure the Obsessive-Compulsive symptoms & Mindfulness attention awareness among OT UG. Study Design-A cross sectional study design. Methods- Written consent from participants was taken. Paper-based version of the Obsessive Compulsive Inventory (OCI) scale and Mindful Attention Awareness Scale(MAAS) were used to assess Obsessive-Compulsive symptoms & Mindfulness among OT UG Occupational therapy students (I to IV year) from School of occupational therapy. Result – Occupational therapy UG students Conclusion– Decrease in Obsessive Compulsive symptoms is leading to increase in mindfulness.


2020 ◽  
pp. 1-4
Author(s):  
Hiral Kotadia ◽  
Gupta Priyanka

Background : Obsessive compulsive symptoms (OCS) have known to co-occur with various psychiatric disorders and have an impact on severity and course of these psychiatric disorders. Knowing the prevalence of OCS in different psychiatric disorders can give a better understanding about the illness and help in shaping its management. This study aims at finding prevalence, types & severity of OCS in patients presenting with different psychiatric disorders in Psychiatry Out patient department at a tertiary care institute. Methodology : A total of 380 patients were included in the. Clinical diagnosis of obsessions & compulsions was made as per criteria in Diagnostic & Statistical Manual for Mental Disorders Fourth Edition, Text Revision (DSM IV- TR). Yale brown Obsessive Compulsive Scale (YBOCS) was applied for assessing severity of obsessive compulsive symptoms. Results & Conclusion: Prevalence of OCs in Psychiatric Disorders to be 5%. The Prevalence of OCS in patients with Psychotic Disorders was found to be 9.9% , in patients with Mood Disorders was found to be 6.6%, in patients with Anxiety Disorders was found to be 2.3% and in patients with Substance Use Disorders was found to be 1.8%. The most common Form of Obsession was Obsessive Thoughts (31.6%), the most common Content was Inanimate-Impersonal (31.6%) and the most common Compulsion was Washing (60%). Mean YBOCS Score of all 19 patients was 9.95 (SD=5.1, Median=9). 36.8% patients had Subclinical Severity (0-7), 47.4% patients had Mild Severity (8-15) and 15.8% patients had Moderate Severity (16-23). Psychotic & mood disorders were further assessed for types & severity of OCS. Though the prevalence of OCS in current study is less compared to previous studies, it still is significant. Thus various psychiatric disorders should be evaluated for presence of OCS.


2014 ◽  
Vol 52 (194) ◽  
pp. 780-784 ◽  
Author(s):  
Bharat Kumar Goit ◽  
Shree Ram Ghimire

Introduction: Obsessive-compulsive disorder has a broadly diverse clinical expression that reflects heterogeneity. Several studies have identified consistent symptom dimensions of obsessivecompulsive disorder. The purpose of this study was to conduct an exploratory symptoms analysis of obsessive-compulsive symptoms in adolescents and adults with obsessive-compulsive disorder. Methods: This was a cross-sectional study conducted in the Department of Psychiatry, National Medical College. This study examined lifetime occurrence of obsessive-compulsive symptoms included in the 13 symptom categories of the Yale–Brown Obsessive Compulsive Scale. Symptoms analysis was performed on 60 patients with obsessive-compulsive disorder. Eight categories of obsessions and six categories of compulsions from Yale–Brown Obsessive Compulsive Scale were included in the analyses. SPSS software package (version 16) was used to analyze the data and shown in the table. Results: Of 60 adolescents and adults, female and male were in the ratio of 1.2:1. Contamination was the most common occurring obsession followed by aggressive obsession. The most common occurring compulsion was checking followed by washing. Only a minority of patients (13.33%) presented predominantly with obsessions however 18.33% patients presented predominantly with compulsions. Certain obsessions and compulsions co-occur to form a cluster. Conclusions: In adolescents and adults, obsessive-compulsive disorder is a multidimensional disorder. Symptom dimensions are predominantly congruent with those described in similar studies of adults with obsessive-compulsive disorder. Keywords: compulsion; obsession; obsessive-compulsive disorder.


2020 ◽  

Objectives: The current study aimed to examine the correlation of the level of homocysteine (Hcy) in the serum with attention and executive functions in patients suffering from type I stable bipolar affective disorder. Methods: The present cross-sectional study was conducted on 170 participants in Huzhou, Zhejiang province, China, within July 2016 to December 2017. The subjects were divided into patients with schizophrenia (n=100) as the study group and healthy volunteers (n=70) as the control group. The Hcy and folic acid levels of fasting ulnar vein serum were determined using the chemiluminescent microparticle immunoassay. Patient attention was evaluated by the Trail Making Test A (TMTA), and executive functions were assessed using the Trail Making Test B (TMTB) and Stroop Color and Word Test (SCWT). Results: The serum Hcy value was significantly higher in the study group than that reported for the control group (19.01±5.83 and 11.40±4.62; P<0.001). The results of several tests of attention (59.39±19.27 and 53.26±14.82; P=0.027) and executive functions (123.75±40.60 and 107.52±29.31; P=0.013) were poorer in the study group. The serum Hcy value positively correlated with the disturbance variables of the TMTA, TMTB, and Trail Making Test. However, the duration of the Stroop-C test (SCT) and SCWT negatively correlated with the correct number of the SCT and SCWT. Conclusions: The increase in the level of serum Hcy is closely correlated with the impairment of attention and executive functions in patients suffering from type I stable bipolar affective disorder.


2021 ◽  
pp. 135910452110176
Author(s):  
Yasser Saeed Khan ◽  
Muayad Jouda ◽  
Yahia Albobali ◽  
Manal Osman Abouelseoud ◽  
Aouatef Souid ◽  
...  

Background: Previous research has established an association between pandemic fears and the development of obsessive-compulsive symptoms mainly in the general population. Aim: To explore whether COVID-19 pandemic fears are associated with obsessive-compulsive symptoms and vice versa in adolescents with preexisting mental and behavioural disorders. Methods: A questionnaire-based cross-sectional study among adolescents with pre-existing mental disorders. The extent of worrying related to the COVID-19 pandemic was measured using the COVID-19 inventory whereas obsessive-compulsive symptoms were assessed using the obsessive-compulsive inventory-revised (OCI-R). Pearson correlation coefficient ( r) was used to explore the relationship between COVID-19 pandemic fears and the development of obsessive-compulsive symptoms. Results: A total of 57 patients out of 63 participants (90.4%) had a COVID-19 inventory score of 12 or higher suggesting that a vast majority of young people with mental disorders had significant pandemic-related worries. Out of these 57 patients, over half (31) had an OCI-R modified score of 17 or higher indicating significant obsessive-compulsive symptoms. A positive correlation was found between the means of the two scores. This relationship was statistically significant – { r = 0.405, Sig. (two-tailed) = 0.001}. Conclusion: Adolescents with mental disorders can exhibit significant pandemic fears and this is likely to be associated with obsessive-compulsive symptoms.


2021 ◽  
Vol 10 (2) ◽  
pp. 274
Author(s):  
Aline P. Vellozo ◽  
Leonardo F. Fontenelle ◽  
Ricardo C. Torresan ◽  
Roseli G. Shavitt ◽  
Ygor A. Ferrão ◽  
...  

Background: Obsessive–compulsive disorder (OCD) is a very heterogeneous condition that frequently includes symptoms of the “symmetry dimension” (i.e., obsessions and/or compulsions of symmetry, ordering, repetition, and counting), along with aggressive, sexual/religious, contamination/cleaning, and hoarding dimensions. Methods: This cross-sectional study aimed to investigate the prevalence, severity, and demographic and clinical correlates of the symmetry dimension among 1001 outpatients from the Brazilian Research Consortium on Obsessive–Compulsive Spectrum Disorders. The main assessment instruments used were the Dimensional Yale–Brown Obsessive–Compulsive Scale, the Yale–Brown Obsessive–Compulsive Scale, the USP-Sensory Phenomena Scale, the Beck Depression and Anxiety Inventories, the Brown Assessment of Beliefs Scale, and the Structured Clinical Interview for DSM-IV Axis I Disorders. Chi-square tests, Fisher’s exact tests, Student’s t-tests, and Mann–Whitney tests were used in the bivariate analyses to compare patients with and without symptoms of the symmetry dimension. Odds ratios (ORs) with confidence intervals and Cohen’s D were also calculated as effect size measures. Finally, a logistic regression was performed to control for confounders. Results: The symmetry dimension was highly prevalent (86.8%) in this large clinical sample and, in the logistic regression, it remained associated with earlier onset of obsessive–compulsive symptoms, insidious onset of compulsions, more severe depressive symptoms, and presence of sensory phenomena. Conclusions: A deeper knowledge about specific OCD dimensions is essential for a better understanding and management of this complex and multifaceted disorder.


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