scholarly journals Blood pressure levels among Indigenous children living at different altitudes

2019 ◽  
Vol 44 (6) ◽  
pp. 659-664 ◽  
Author(s):  
Valeria Hirschler ◽  
Claudia Molinari ◽  
Gustavo Maccallini ◽  
Patricia Intersimone ◽  
Claudio Daniel Gonzalez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Sea Level ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Study Data ◽  
Cross Sectional ◽  
Confounding Variables ◽  
Indigenous Children ◽  
Control And Prevention ◽  
Different Altitudes

The objective was to compare blood pressure (BP) levels in 2 groups of Indigenous Argentine school children from similar ethnic backgrounds but living at different altitudes. One hundred and fifty-two (46.3%) children (age, 4–14 years) from San Antonio de los Cobres (SAC), at 3750 m above sea level, and 176 children (53.7%) from Chicoana (CH), at 1400 m above sea level, participated in this cross-sectional study. Data for children’s anthropometry, BP, glucose, lipids, vitamin D, and insulin, as well as mothers’ height and weight were assessed. Hypertension was defined as BP ≥ 95th percentile. The prevalence of overweight/obesity among children was significantly lower in SAC (n = 17, 11.2%) than in CH (n = 74, 42%) (body mass index (BMI) > 85th percentile per US Centers for Disease Control and Prevention norms). However, the prevalence of hypertension was significantly higher among children in SAC (n = 15, 9.9%) than among those in CH (n = 2, 1.1%). Children were divided into 4 groups by mean arterial BP quartiles for comparison by ANOVA. As mean arterial BP increased, age, BMI, glucose, triglycerides, triglycerides/high-density lipoprotein cholesterol, and insulin levels increased significantly. Multiple linear regression analyses showed that children’s mean arterial BP was significantly associated with altitude adjusted for confounding variables (R2 = 0.42). Furthermore, when mean arterial BP was replaced by systolic BP (R2 = 0.51) or diastolic BP (R2 = 0.33), similar results were obtained. Our results suggest that Indigenous children who live permanently at high altitude have higher levels of BP, adjusted for confounding variables. Routine BP measurements conducted in the SAC community could be essential for the prevention of cardiovascular disease.

scholarly journals COMPARISON OF ANXIETY LEVEL, BLOOD PRESSURE AND PULSE PARAMETERS OF PATIENTS WITH AND WITHOUT CORONARY ANGIOGRAPHY EXPERIENCE: A CROSS-SECTIONAL STUDY

2021 ◽  
Vol 54 (1) ◽  
pp. 107-115
Author(s):  
Yasemin Altınbaş ◽  
Emine Derya Derya Ister
Keyword(s):  
Blood Pressure ◽  
Coronary Angiography ◽  
Trait Anxiety ◽  
Blood Pressure Measurement ◽  
Cross Sectional Study ◽  
Study Data ◽  
Cross Sectional ◽  
Significant Difference ◽  
State And Trait Anxiety ◽  
The Mean

Objective: The study aimed to compare state and trait anxiety, blood pressure, and heart rate of patients with and without coronary angiography experience who undergo coronary angiography intervention. Methodology: This study is cross-sectional comparative research. A total of 160 patients, including 80 patients undergo for the first time coronary angiography and 80 patients with at least one experience of coronary angiography were included in the sample of the study. In the study, data were collected using 'Patient Information Form' and 'State-Trait Anxiety Inventory', blood pressure measurement device, and pulse oximeter. Results: The mean of state anxiety scores of the patients with and without CA experience were 39.35±5.31 and 39.98±4.04, respectively; (p=0.395). The mean of trait anxiety scores of the patients with and without CA experience were 44.73±6.84 and 44.51±6.05, respectively (p=0.826).  There was no statistically significant difference observed in state and trait anxiety between two groups. Before the CA procedure, the systolic and diastolic blood pressure average of the patients with CA experience were statistically higher than those without CA experience (p<0.05). Conclusion: The anxiety levels of the patients before the CA were observed to be similar and moderate, regardless of their CA experience. It was observed that patients with CA experience before CA procedure had higher systolic and diastolic blood pressures compared to the group without experience.

scholarly journals Dietary Inflammatory Index Score and Its Association with Body Weight, Blood Pressure, Lipid Profile, and Leptin in Indonesian Adults

Nutrients ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 148 ◽  
Author(s):  
Harry Muhammad ◽  
Marleen van Baak ◽  
Edwin Mariman ◽  
Dian Sulistyoningrum ◽  
Emy Huriyati ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Dietary Inflammatory Index ◽  
Cross Sectional ◽  
Inflammatory Index ◽  
Plasma Leptin

It was previously reported that dietary intake is an important trigger for systemic inflammation and one of the lifestyle factors for the development of cardiovascular diseases. The aim of this study was to evaluate the association between Dietary Inflammatory Index (DII) score and body weight, blood pressure, lipid profile and leptin in an Indonesian population. This was a cross-sectional study conducted in 503 Indonesian adults. The DII score was calculated based on data of 30 nutrients and food components. Anthropometric profile, blood pressure, lipid profile, and leptin were measured. The association of these variables with the DII score was analyzed. The DII score was not associated with body weight, body mass index (BMI), body fat, waist circumference, hip circumference, systolic and diastolic blood pressure, triglycerides, and high-density lipoprotein (HDL) (both unadjusted and after adjustment for covariates). However, plasma leptin concentration was significantly associated with the DII score (B = 0.096, p = 0.020). Plasma leptin also increased significantly across tertiles of the DII score (ANCOVA, p = 0.031). This positive association between the DII score and plasma leptin concentration suggests a role for the inflammatory properties of the diet in regulating adipose tissue inflammation.

Melatonin and cryptochrome 2 in metabolic syndrome patients with or without diabetes: a cross-sectional study

2018 ◽  
Vol 35 (2) ◽  
Author(s):  
Ibrahim Abdul Kareem Al-Sarraf ◽  
Violet Kasabri ◽  
Amal Akour ◽  
Randa Naffa
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
P Value ◽  
Metabolic Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cryptochrome 2

Abstract Background Metabolic syndrome (MetS) is a cluster of metabolic risk factors which increases the chances for future cardiovascular diseases, as well as diabetes. The underlying causes of MetS include overweight and obesity, physical inactivity and genetic factors. Our intension here was to focus in this study on the importance of the chronobiology, represented by melatonin (MT) and cryptochrome 2 (CRY2), in developing MetS and type 2 diabetes mellitus (T2DM). Thus, we aimed to compare MT and CRY2 plasma levels and correlate both biomarkers with adiposity, atherogenicity and hematological indices in MetS and T2DM cohorts. Methods In a cross-sectional study, 28 normoglycemic lean subjects (controls), 29 normoglycemic MetS subjects and 30 MetS (pre-diabetic/diabetic) were recruited. Results MT (pg/mL) was elevated significantly in MetS arm p-value < 0.05, whereas CRY2 levels (ng/mL) were markedly higher in both MetS groups (non-diabetic and pre-diabetic/diabetic) (all with p-value < 0.001). A reciprocal MT-CRY2 relationship was observed in the MetS (non-diabetic) group (p-value = 0.003). Of note in the total study population, both MT and CRY2 proportionally correlated with each of the following: atherogenicity index of plasma (AIP), waist circumference (WC) and systolic blood pressure (SBP) (all with p-value < 0.05) for MT and CRY2, respectively). Whereas MT correlated inversely with high-density lipoprotein-cholesterol (HDL-C) (p-value < 0.05). Additionally, CRY2 correlated directly with each of the following: diastolic blood pressure (DBP), total cholesterol (TC), low-density lipoprotein (LDL-C), hip circumference (HC), body adiposity index (BAI), weight-to-height (WHtR) ratio, mean platelet volume (MPV) and platelet/lymphocyte ratio (PLR) (p-value < 0.05). Conclusion These findings substantiate that both metabolic risk biomarkers can be prognostic tools and pharmacotherapeutic targets to slowdown the accelerated nature of T2DM.

scholarly journals C-Peptide Versus Insulin: Relationships with Risk Biomarkers of Cardiovascular Disease in Metabolic Syndrome in Young Arab Females

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
A. Abdullah ◽  
H. Hasan ◽  
V. Raigangar ◽  
W. Bani-Issa
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
High Sensitivity ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Health Concern ◽  
Cross Sectional ◽  
C Peptide

Background. Obesity is a major health concern and is associated with metabolic syndrome (MetS) that increases the risk for cardiovascular disease (CVD). Since little is known about the relationships between MetS components and CVD in overweight/obese young Arab females, our study aimed at examining these relationships and further to explore the associations between connecting peptide (C-peptide) and insulin with these biomarkers.Subjects and Methods. In this cross-sectional study, 80 apparently healthy young Arab females were recruited and grouped by their body mass index (BMI) into normal-weight (GI) and overweight/obese (GII) groups.Results. The two groups significantly differed in BMI, waist circumference (WC) and values of biomarkers, namely, leptin, fasting insulin, uric acid (UA), insulin resistance (HOMA-IR), C-peptide, high-sensitivity C-reactive protein (hs-CRP), high-density lipoprotein cholesterol (HDL-C), systolic blood pressure (SBP), and diastolic blood pressure (DBP). C-peptide significantly correlated with WC, leptin, UA, and HDL-C and was predicted by three biomarkers; UA, WC and HDL-C. Whereas, insulin significantly correlated with only two biomarkers including leptin and DBP and was predicted by UA and DBP.Conclusions. The present study highlighted the association between MetS and CVD in young Arab females and the possible role of C-peptide in the prediction of CVD.

scholarly journals Impact of Dietary Fibre Intake on Body Composition and Cardiometabolic Disease Risk Markers

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Ezgi Ozen ◽  
Elinor Read ◽  
Rada Mihaylova ◽  
Michelle Weech ◽  
Julie Lovegrove ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Composition ◽  
Dietary Fibre ◽  
Ldl Cholesterol ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Risk Markers ◽  
Cross Sectional ◽  
Fibre Intake ◽  
Dietary Fibre Intake

AbstractBackground:Diets higher in fibre have been associated with beneficial effects on cardiometabolic disease (CMD) risk markers including obesity, blood pressure and cholesterol levels. However, the relationship between dietary fibre intake and body composition is unclear. Therefore, the objective of the study was to further assess the association between fibre intake, body composition and CMD risk markers.Materials and Methods:A single-centred cross-sectional study was conducted in 277 healthy adults (n = 107 men and n = 170) women with a mean age of 41 (SD 16) y and body mass index (BMI) of 23.9 (SD 3.8) kg/m2. Total body composition was measured by dual energy x-ray absorptiometry and dietary intake was assessed with a 4-day weighed food diary.CMD risk markers included fasting lipids and glucose quantified using an ILAB 600 clinical chemistry analyser and clinic blood pressure measured using an Omron blood pressure monitor.Results:Average AOAC fibre intake in the cohort was 23.0 (SD 9) g/day, with higher intakes found in men (25.0 (SD 10.3) g/day) than women (21.9 (SD 7.8) g/day; P = 0.015). AOAC fibre intakes were significantly weakly correlated with weight (rs = 0.142), percentage body fat (rs = 0.193), bone mineral density (rs = 0.156) and fat free mass (rs = 0.257; P ≤ 0.009), and inversely correlated with fasting total cholesterol (rs = -0.124), low-density lipoprotein (LDL)-cholesterol (rs = 0.144) and total to high-density lipoprotein-cholesterol ratio (rs = -0.129; P ≤ 0.042). After stratifying data according to quartiles of AOAC fibre intake and adjusting for covariates (including age, sex, BMI, weight, energy expended per day through physical activity and total energy intake per day) total and LDL-cholesterol concentrations were significantly lower in quartiles (Q)3 (21.0–29.5 g/d) and Q4 (30–63.5 g/d) than Q1 (3.0–18.8 g/d) and Q2 (19.3–20.9 g/d). Systolic blood pressure was also lower in Q4 than Q1 and Q2 (P < 0.05). Anthropometric and body composition measures were not found to be different across quartiles of increasing AOAC fibre intake.Discussion:Findings from this cross-sectional study have revealed daily fibre consumption greater than 21 g to be associated with lower fasting total and LDL cholesterol, and intakes ≥ 30 g also associated with lower systolic blood pressure. With only 9% of UK adults meeting the current recommended intake, raising public awareness of the importance of dietary fibre is an important strategy for CMD prevention.

scholarly journals Hubungan paparan bising dan profil lipid dengan gangguan pendengaran pada pekerja pabrik minyak goreng

2016 ◽  
Vol 46 (1) ◽  
pp. 1
Author(s):  
Adlin Adnan ◽  
Renold Yurensa
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Noise Exposure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Study Data ◽  
High Density ◽  
Average Intensity ◽  
Cross Sectional

Latar belakang: Gangguan pendengaran akibat bising (GPAB) adalah komplikasi yang palingumum disebabkan oleh paparan terhadap bising, meskipun ada beberapa komplikasi lain yang bisadisebabkan oleh paparan bising. Komplikasi metabolik dari paparan terhadap bising telah dievaluasi olehberbagai penelitian.Tujuan: Meneliti hubungan antara GPAB dengan kadar profil lipid pada pekerja yangterpapar bising di lingkungan kerja.Metode: Penelitian ini bersifat deskriptif analitik dengan desain crosssectional study. Data diperoleh melalui proses wawancara, pemeriksaan audiometri, dan pemeriksaankadar profil lipid.Hasil: Rerata intensitas kebisingan bagian proses 98 dB, dan non-proses berkisar 46-98 dB. Berdasarkan hasil pemeriksaan audiometri terhadap 50 pekerja yang memenuhi kriteria inklusidan eksklusi, didapatkan 26 orang (52%) dengan GPAB tuli sensorineural dan 24 orang (48%) tidakmengalami GPAB. Kami menemukan hubungan signifikan antara paparan bising pada pekerja denganpeningkatan kadar trigliserida (TG), total kolesterol (TC), low-density lipoprotein (LDL), dan penurunankadar high-density lipoprotein (HDL) (p<0,05). Terdapat hubungan antara kadar TG yang tinggi terhadapterjadinya GPAB pada pekerja yang terpapar bising dengan intensitas >85 dB (p<0,05) dan tidak dijumpaihubungan peningkatan kadar TC, LDL, dan penurunan kadar HDL terhadap terjadinya GPAB (p>0,05).Kesimpulan: Pada penelitian ini, ada hubungan antara hiperlipidemia dengan GPAB. Pekerja denganhipertrigliseridemia yang tepapar bising >85 dB berisiko lebih besar menderita GPAB. Kata kunci: Kebisingan, GPAB, profil lipid ABSTRACTBackground: Noise induced hearing loss (NIHL) is the most common complication that causedby noise exposure, although there are other complications as a result of noise exposure. Metaboliccomplications from noise exposure have been evaluated in various studies. Purpose: To examine therelationship between NIHL with lipid profile in workers who are exposed to noise in workplace. Methods:The study design was analytic descriptive with cross-sectional study. Data collection was done throughinterviews, audiometry screening, and lipid profile examinations. Results: The average intensity in processsection was 98 dB, and in non-process section ranged between 46-98 dB. The results of audiometricexamination of the 50 workers who met the inclusion criteria, were 26 persons (52%) with sensorineuralNIHL and 24 persons (48%) did not experience NIHL. We found a significant association between noiseexposure among workers with elevated levels of triglyceride (TG), total cholesterol (TC), low-densitylipoprotein (LDL), and decreased high-density lipoprotein (HDL) levels (p<0,05). There was highcorrelation beween TG levels with the NIHL among workers who are exposed to noise >85 dB (p<0,05),and no correlation between elevated levels of TC, LDL and decreased HDL levels with NIHL (p>0,05).Conclusion: We found a significant relationship between hyperlipidemia and NIHL. Workers withhypertriglyceridemia had greater risk of suffering NIHL when exposed to noise >85 dB in the workplace. Keywords: Noise, NIHL, lipid profile

scholarly journals Serum FGF21 levels are altered by various factors including lifestyle behaviors in male subjects

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kaori Nakanishi ◽  
Chisaki Ishibashi ◽  
Seiko Ide ◽  
Ryohei Yamamoto ◽  
Makoto Nishida ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Alcohol Consumption ◽  
Smoking Status ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Health Examination ◽  
Lifestyle Behaviors ◽  
Gamma Glutamyl Transpeptidase ◽  
Cross Sectional ◽  
Consumption Frequency

AbstractFibroblast growth factor (FGF) 21 has various functions, including glucose and lipid metabolism. This cross-sectional study aimed to investigate specific conditions that might influence the functions of FGF21. 398 men who underwent a health examination were enrolled in this study. Physical and biochemical parameters and information on several lifestyle behaviors were obtained from all subjects. FGF21 levels correlated with age, body mass index (BMI), waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (γ-GTP), uric acid, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDLC), fasting plasma glucose (FPG), and HbA1c. Moreover, FGF21 levels were significantly associated with lifestyle behaviors, including smoking status and breakfast and alcohol consumption frequency. Multivariable regression analysis showed that age, ALT, γ-GTP, smoking status, and breakfast and alcohol consumption frequency were independent variables for FGF21 levels. Assessment among the non-obese and obese groups showed that FGF21 levels correlated with WC, SBP, and TC only in the non-obese group. Thus, serum FGF21 levels were affected by several factors, including lifestyle behaviors, age, and liver function. To assess the functions of FGF21 in individuals, considering these factors would be essential.

Magnesium intake is associated with the metabolically healthy obese phenotype

2021 ◽  
pp. jim-2021-001841
Author(s):  
Fernando Guerrero-Romero ◽  
Gerardo Morales-Gurrola ◽  
Lucía Preza-Rodríguez ◽  
Alejandra Gómez-Barrientos ◽  
Ana I Olivas-Martínez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Abdominal Obesity ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Magnesium Intake ◽  
Metabolically Healthy Obese ◽  
Low Hdl ◽  
Healthy Obese ◽  
Metabolically Healthy

Although magnesium intake is inversely associated with the risk of metabolic abnormalities, whether magnesium intake plays a role on metabolically healthy obese (MHO) phenotype has not been explored. Therefore, the purpose of this study was to determine whether the magnesium intake is associated with the MHO phenotype. Apparently, healthy women and men aged 20–65 years with obesity were enrolled in a cross-sectional study. Subjects were allocated into MHO (n=124) and metabolically unhealthy obese (MUO) (n=123) groups. MHO phenotype was defined by abdominal obesity (waist circumference ≥90 cm in men and ≥80 cm in women) and none, or not more than one of the following risk factors: triglyceride levels ≥150 mg/dL; high-density lipoprotein cholesterol (HDL-C) levels <40 mg/dL in men and <50 mg/dL in women; fasting glucose ≥100 mg/dL; and systolic blood pressure ≥130 mm Hg and/or diastolic blood pressure ≥85 mm Hg. The MUO individuals were characterized by abdominal obesity and the presence of two or more of the aforementioned criteria. The proportion of individuals with high blood pressure (40.7% vs 5.6%, p<0.001), hyperglycemia (69.1% vs 16.9%, p<0.001), hypertriglyceridemia (84.6% vs 36.3%, p<0.001), and low HDL-C (51.2% vs 12.9%, p<0.001) was significantly higher in the MUO individuals as compared with individuals in the MHO group. The logistic regression analysis adjusted by sex and age showed that dietary magnesium intake is significantly associated with the MHO phenotype (OR=1.17; 95% CI 1.07 to 1.25, p=0.005). Our results show that magnesium intake is significantly associated with the MHO phenotype.

scholarly journals Glycaemic, blood pressure and low-density lipoprotein-cholesterol control among patients with diabetes mellitus in a specialised clinic in Botswana: a cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e026807 ◽  
Author(s):  
Julius Chacha Mwita ◽  
Joel M Francis ◽  
Bernard Omech ◽  
Elizabeth Botsile ◽  
Aderonke Oyewo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Low Density ◽  
Sectional Study ◽  
Low Density Lipoprotein Cholesterol ◽  
Cross Sectional ◽  
Patients With Diabetes

ObjectiveControl of glycaemic, hypertension and low-density lipoprotein-cholesterol (LDL-C) among patients with type 2 diabetes mellitus (T2DM) is vital for the prevention of cardiovascular diseases. The current study was an audit of glycaemic, hypertension and LDL-C control among ambulant patients with T2DM in Botswana. Also, the study aimed at assessing factors associated with attaining optimal glycaemic, hypertension and LDL-C therapeutic goals.DesignA cross-sectional study.SettingA specialised public diabetes clinic in Gaborone, Botswana.ParticipantsPatients with T2DM who had attended the clinic for ≥3 months between August 2017 and February 2018.Primary outcome measureThe proportion of patients with optimal glycaemic (HbA1c<7%), hypertension (blood pressure <140/90 mm Hg) and LDL-C (<1.8 mmol/L) control.ResultsThe proportions of patients meeting optimal targets were 32.3% for glycaemic, 54.2% for hypertension and 20.4% for LDL-C. Age≥ 50 years was positively associated with optimal glycaemic control (adjusted OR [AOR] 5.79; 95% CI 1.08 to 31.14). On the other hand, an increase in diabetes duration was inversely associated with optimal glycemic control (AOR 0.91; 95% CI 0.85 to 0.98). Being on an ACE inhibitor was inversely associated with optimal hypertension control (AOR 0.35; 95% CI 0.14 to 0.85). Being female was inversely associated with optimal LDL-C control (AOR 0.24; 95% CI (0.09 - 0.59).ConclusionPatients with T2DM in Gaborone, Botswana, presented with suboptimal control of recommended glycaemic, hypertension and LDL-C targets. These findings call for urgent individual and health systems interventions to address key determinants of the recommended therapeutic targets among patients with diabetes in this setting.

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