EFFECT OF HYPERVITAMINOSIS A ON INTESTINAL LIPIDS OF RATS

1967 ◽  
Vol 45 (9) ◽  
pp. 1413-1418 ◽  
Author(s):  
U. K. Misra
Keyword(s):  
Body Weight ◽  
Phosphatidic Acid ◽  
Food Consumption ◽  
Silicic Acid ◽  
Silicic Acid Column ◽  
Total Lipids ◽  
Hypervitaminosis A ◽  
Daily Food ◽  
Significant Difference ◽  
And Control

The effect of intramuscular administration of retinol (100,000 I.U. daily for 13 days) on intestinal lipids of young rats has been studied. The administration of toxic doses of retinol significantly increased the total lipids of intestine as compared with the control. A significant increase in intestinal monoglycerides, and in phosphatidic acid and polyglycerol phosphatide (present in the phospholipid fraction eluted from a silicic acid column with 5% methanolic chloroform) was observed in the hypervitaminotic A rats. There was no significant difference in the daily food consumption and body weight between the hypervitaminotic A and control rats at the time of sacrifice.

scholarly journals Aberrant Lighting Causes Anxiety-like Behavior in Mice but Curcumin Ameliorates the Symptoms

Animals ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2590
Author(s):  
Dhondup Namgyal ◽  
Kumari Chandan ◽  
Sher Ali ◽  
Ajaz Ahmad ◽  
Maha J. Hashim ◽  
...  
Keyword(s):  
Body Weight ◽  
Research Field ◽  
The Body ◽  
Laboratory Animals ◽  
Artificial Lighting ◽  
Lighting Conditions ◽  
Daily Food ◽  
Significant Difference ◽  
Negative Effect ◽  
Lighting Systems

In the modern research field, laboratory animals are constantly kept under artificial lighting conditions. However, recent studies have shown the effect of artificial light on animal behavior and metabolism. In the present study on mice, following three weeks of housing in dim light at night (dLAN; 5lux) and complete darkness (DD; 0lux), we monitored the effect on body weight, daily food intake, anxiety-like behavior by employing the open field test, and expression of the period (PER1) gene. We also studied the effect of oral administration of different concentrations of curcumin (50, 100, and 150 mg/kg) for three weeks in the same mice and monitored these parameters. The exposure to dLAN had significantly increased the anxiety-like behavior and body weight possibly through the altered metabolism in mice, whereas exposure to DD caused increased anxiety but no significant difference in weight gain. Moreover, the expression of the PER1 gene involved in sleep was also found to be decreased in the aberrant light conditions (dLAN and DD). Although the treatment of curcumin had no effect on body weight, it ameliorated the anxiety-like behavior possibly by modulating the expression of the PER1 gene. Thus, alteration in the light/dark cycle had a negative effect on laboratory animals on the body weight and emotions of animals. The present study identifies the risk factors associated with artificial lighting systems on the behavior of laboratory animals and the ameliorative effects of curcumin, with a focus on anxiety-like behavior.

Influence of starvation on enzyme-induced emphysema

1980 ◽  
Vol 48 (2) ◽  
pp. 284-288 ◽  
Author(s):  
H. Sahebjami ◽  
C. L. Vassallo
Keyword(s):  
Body Weight ◽  
Isotonic Saline ◽  
Internal Surface ◽  
High Volume ◽  
Elastic Recoil ◽  
Internal Surface Area ◽  
Adult Rats ◽  
Final Body Weight ◽  
Daily Food ◽  
And Control

Adult rats were exposed to an aerosol of 10% papain for 8 h twice in a 2-wk interval. The control rats were exposed to isotonic saline in the same manner. Three weeks after the final exposure rats were divided into four groups: emphysema-fed, emphysema-starved, control-fed, and control-starved. Starved animals received one-third of their measured daily food consumption and water ad libitum for 6 wk. Final body weight, dry and wet weights of lungs and postfixation lung volume (VL) were significantly lower in starved rats. Dry-to-wet weight ratios were not significantly different among the groups, but VL/body weight was significantly higher in starved animals. Elastic recoil pressure of lung tissue determined in saline-filled lungs decreased and chord compliance over mid- and high-volume ranges increased significantly in starved animals both in control and emphysema groups. Mean linear intercept of air spaces was greater and internal surface area was smaller in starved rats in each group. Therefore, it appears that starvation aggravates the preexisting emphysematous processes in rat lungs.

Alterations in plasma constituents, growth and egg production traits due to selection in three genotypes of Japanese quail

2018 ◽  
Vol 156 (1) ◽  
pp. 118-126 ◽  
Author(s):  
G. S. Farahat ◽  
B. Y. Mahmoud ◽  
E. M. El-Komy ◽  
E. A. El-Full
Keyword(s):  
Body Weight ◽  
Japanese Quail ◽  
Egg Production ◽  
Body Weight Gain ◽  
Egg Mass ◽  
Production Traits ◽  
Total Lipids ◽  
Laying Performance ◽  
Productive Traits ◽  
And Control

AbstractThe present investigation was carried out to estimate the effects of genotype and sex on growth and laying performance and assess the variations in plasma constituents in the tested genotypes and their relations with productive traits after four generations of selection. Data of growth and laying performance on 1440 females and males of Japanese quail were taken from the three quail genotypes: maternal (MG), long shank length (LSG28) and control (CG) genotypes. Genotype significantly affected all studied growth productive traits, favouring selected genotypes. The LSG28surpassed MG in total protein, albumin (Alb), globulin (Glob), triglycerides and Alb/Glob ratio and lowered both cholesterol and total lipids (TL). Sex significantly favoured females, which had higher body weight, longer shank length at 35 days of age and higher body weight gain during the period from 1 to 35 days of age. Females showed significantly higher concentrations of both Alb and TL than males. The MG exceeded LSG28in fertility and hatchability per cent. Correlations for both growth and productive traits with plasma constituents revealed inconsistent trends in either magnitude or direction. Four generations of selection resulted in substantial phenotypic improvements in most growth and productive traits, as well as plasma constituents studied in LSG28, and favoured MG in maturity, days needed to produce the first ten eggs, higher egg production per cent and heavier egg mass.

scholarly journals Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide

2018 ◽  
Vol 52 (4) ◽  
pp. 185-191
Author(s):  
Tomomi Nobashi ◽  
Tsuneo Saga ◽  
Yuji Nakamoto ◽  
Yoichi Shimizu ◽  
Sho Koyasu ◽  
...  
Keyword(s):  
Body Weight ◽  
Small Intestine ◽  
Low Dose ◽  
Control Group ◽  
High Dose ◽  
Fdg Uptake ◽  
Significant Difference ◽  
Mouse Small Intestine ◽  
Long Acting ◽  
And Control

AbstractObjective. This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. Methods. Mean18F-FDG uptake in the mouse small intestine and colon with Met exposure was compared with that in control mice. In the Met group, high-dose (1.0 mg/kg body weight) and low-dose (0.1 mg/kg body weight) loperamide were introduced, and18F-FDG uptake in the small intestine and colon was compared with that of control mice administered high-dose loperamide. The percent injected dose of18F-FDG per gram of tissue (%ID/g) in the extracted tissues was then determined. Results.18F-FDG uptake increased significantly in the small intestine (0.64±0.06 vs. 1.01±0.15, p=0.040) and, especially, the colon (0.46±0.13 vs. 2.16±0.51, p<0.001) after Met exposure. Neither high-dose nor low-dose loperamide significantly reduced18F-FDG uptake in the small intestine (0.82±0.31 vs. 0.84±0.22, p=0.93 and 0.78±0.25 vs. 0.70±0.15, p=0.13, respectively) or colon (2.13±0.41 vs. 1.67±0.55, p=0.063 and 1.77±0.39 vs. 1.80±0.25, p=0.56, respectively). The colonic %ID/g was significantly higher in Met groups irrespective of loperamide introduction than in control group, whereas the significant difference in the small intestine was observed only between Met and control groups. Conclusion. Metformin increased18F-FDG uptake in intestines especially in colon. Loperamide administration partially, but not sufficiently, suppresses the Met-induced increased colonic uptake of18F-FDG.

Influence of Food Competition, Predation, and Cannibalism on Walleye (Stizostedion vitreum vitreum) and Sauger (S. canadense) Populations in Lake of the Woods, Minnesota

1976 ◽  
Vol 33 (9) ◽  
pp. 1946-1954 ◽  
Author(s):  
William A. Swenson ◽  
Lloyd L. Smith Jr.
Keyword(s):  
Body Weight ◽  
Food Consumption ◽  
Food Availability ◽  
Food Competition ◽  
Stizostedion Vitreum ◽  
Commercial Catch ◽  
Lake Of The Woods ◽  
Daily Food ◽  
Influence Of Food ◽  
Catch Statistics

Feeding relationships between walleye, Stizostedion vitreum vitreum, and sauger, Stizostedion canadense, in Lake of the Woods, Minnesota, were investigated. Effectiveness of food consumption estimates in measuring feeding interactions was defined. Differences in walleye and sauger distribution, food habits, and feeding strata reduced interactions. Walleye feeding rate varied from 0.5 to 4.1% of body weight per day and was limited by prey abundance during June and July. Higher August and September prey densities did not influence walleye food consumption. Daily food consumption of sauger varied from 0.5 to 3.5% of body weight independent of changes in food availability. Relationships between the number of prey consumed daily by walleye and sauger and the decline in abundance of prey species suggested that predation was important in controlling food availability, and was the major cause of food competition and its limiting effect on walleye growth.Analysis of commercial catch statistics suggested that factors other than predation influenced walleye survival. However, the relationship between the number of young-of-the-year walleye consumed and their abundance in the lake demonstrated predation by sauger may be important to walleye survival.

Food Consumption of Walleye (Stizostedion vitreum vitreum) and Sauger (S. canadense) in Relation to Food Availability and Physical Conditions in Lake of the Woods, Minnesota, Shagawa Lake, and Western Lake Superior

1977 ◽  
Vol 34 (10) ◽  
pp. 1643-1654 ◽  
Author(s):  
William A. Swenson
Keyword(s):  
Body Weight ◽  
Food Consumption ◽  
Yellow Perch ◽  
Prey Density ◽  
Lake Superior ◽  
Stizostedion Vitreum ◽  
Lake Of The Woods ◽  
Daily Food Consumption ◽  
Western Lake ◽  
Daily Food

Measurement of walleye (Stizostedion vitreum vitreum) daily food consumption rates and prey density in Lake of the Woods, Minnesota, Shagawa Lake, and western Lake Superior showed a general relationship exists between the two variables. Daily food consumption increased from 1 to 3% of body weight at prey densities up to 400 mg∙m−3. Abundance of age 0 yellow perch (Perca flavescens) in Lake of the Woods, Minnesota, and Shagawa Lake resulted in much higher prey densities and daily food consumption to 4% of body weight. In Lake Superior where walleye fed exclusively on rainbow smelt (Osmerus mordax), prey density did not exceed 300 mg ∙m−3 and daily food consumption averaged less than 2.5% of body weight.Hourly food consumption by walleye changed in response to variation in prey availability and light intensity. Night feeding predominated during July and August when walleye fed on pelagic age 0 yellow perch. Feeding appeared to be continuous or crepuscular during June and September when larger demersal prey fish or invertebrates were eaten. Food consumption declined when prey concentrated near aquatic macrophytes and under conditions of high light intensity. Walleye daily food consumption was not influenced by a change in temperature from 20 to 15 °C.Daily food consumption of Lake of the Woods, Minnesota sauger (Stizostedion canadense) averaged less than walleye and was influenced by wave activity and prey density. Demersal prey was utilized by sauger throughout the 24 h-day. Key words: Percidae, food consumption, behavior, feeding, walleye, Stizostedion vitreum vitreum, sauger, S. canadense, light

scholarly journals The effect of interscapular brown adipose tissue removal on body-weight and cold response in the mouse

1982 ◽  
Vol 47 (3) ◽  
pp. 653-658 ◽  
Author(s):  
E. Connolly ◽  
R. D. Morrisey ◽  
J. A. Carnie
Keyword(s):  
Body Weight ◽  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cold Response ◽  
Interscapular Brown Adipose Tissue ◽  
Fat Extraction ◽  
Brown Adipose ◽  
Significant Difference ◽  
Weight Protein ◽  
And Control

1. The removal of the interscapular brown adipose tissue (IBAT) led to an increase in body-weight of normal, lean mice as compared to anaesthetized controls.2. No significant difference in food consumption could be detected between the two groups of mice over the period of the experiment.3. Fat extraction of the whole carcasses with chloroform: methanol showed a statistically significant increase in fat content in the animals without IBAT.4. There was no apparent failure in the operated animals to sustain core temperature when exposed to a cold stress situation (4° for 24 h).5. There was no difference in the wet weight, protein content or cytochrorne oxidase content of the dorso-cervical brown adipose tissue (DCBAT) between operated and control mice. This is indicative of a lack of proliferation of other brown adipose tissue sites in the operated mice in response to the removal of the IBAT.6. It is suggested that brown adipose tissue is implicated in dietary themiogenesis in the mouse.

Effect of body weight and temperature on the maximum daily food consumption of Esox lucius

1994 ◽  
Vol 44 (1) ◽  
pp. 165-167 ◽  
Author(s):  
A. Salam ◽  
P. M. C. Davies
Keyword(s):  
Body Weight ◽  
Food Consumption ◽  
Esox Lucius ◽  
Daily Food Consumption ◽  
Daily Food

Computed Chest Tomography in Rats with Pulmonary Damage Due to Microembolism

1986 ◽  
Vol 27 (6) ◽  
pp. 723-728 ◽  
Author(s):  
T. Wegener ◽  
G. Wegenius ◽  
A. Hemmingsson ◽  
B. Jung ◽  
T. Saldeen
Keyword(s):  
Body Weight ◽  
Early Stage ◽  
Good Method ◽  
Lung Weight ◽  
Significant Difference ◽  
Pulmonary Damage ◽  
The Right ◽  
Alveolar Oedema ◽  
And Control ◽  
Attenuation Values

Computed chest tomography was performed in 13 rats with pulmonary damage due to microembolism, caused by injection of thrombin (500 NIH/kg body weight) and tranexamic acid, a fibrinolytic inhibitor (200 mg/kg body weight), and in 9 control rats. The purpose of the investigation was to perform attenuation measurements at two levels of the right lung, each with three regions of interest (anterior, mid and posterior). Alterations in attenuation, compared with controls, were correlated with lung weight. Compared with controls, the attenuation was significantly increased in the anterior and posterior regions at both levels in animals with pulmonary damage, but not in the mid regions. There was a statistically significant correlation between increasing attenuation and increasing lung weight. A significant difference was found between damaged and control lungs regarding the microscopic grade of interstitial oedema, alveolar oedema and fibrin. Histograms of attenuation values in computed tomograms might be of value in detecting alveolar oedema. It is concluded that computed chest tomography is a good method for detecting pulmonary oedema at an early stage of experimental microembolism in the rat.

scholarly journals Respiratory Stress of Sub-Lethal Concentration of Chlorine on Oreochromis niloticus

2021 ◽  
Vol 11 (3) ◽  
Author(s):  
Asna Salam ◽  
A.U. Arun ◽  
Shalu Soman
Keyword(s):  
Body Weight ◽  
Oreochromis Niloticus ◽  
Movement Control ◽  
Aquatic Organisms ◽  
Dilution Method ◽  
A Value ◽  
Significant Difference ◽  
Minimum Number ◽  
Serial Dilution Method ◽  
And Control

In aquatic environment, one of the most significant manifestations of the toxic stress on aquatic organisms, especially fishes are the over stimulation or depression of respiratory activities. These variations in respiratory activities have been used as in indicator of environmental stress. This study was aimed to assess the sub-lethal toxicity of chlorine through respiratory stress on Oreochromis niloticus. It was noticed that in all dosage experiments as the concentration increased rate of gill movement decreased. The rate of gill movement during the first minute after the dosage in control was 128 per minute. Serial dilution method employed in this study helped to assess the LC50 of chlorine and the value noted was 2 ppm. The minimum number of gill movement noted was in 20ppm dosage and the value was 98 per minute whereas the maximum noted was in 5ppm dosage and the value was 101 per minute. In 60th minutes after dosage also the control showed a value of 126 per minute and 20 ppm dosage showed a very low value such as 32 per minute whereas 5ppm dosage of chlorine showed a reasonably good value of 61 per minute. It was noted that in the case of average gill movement, control showed a very high value such as 127 per minute, whereas 5ppm dosage of chlorine showed a reasonably good value such as 84 per minute, and 20 ppm dosage showed a low value 72 per minute. When a comparison was made between control and differently dosed fishes, it was observed that in all dosed cases the average gill movement was very low when compared with control. A significant difference exists between gill movement in the dosed group and control (P<0.05). Consumption of oxygen increased with an increase in dosage and decreased with increased period of exposure. In control the average oxygen consumption was 0.012 mg/ml/gm body weight, in 5ppm it was 0.014 mg/ml/gm body weight, in 10 ppm it was 0.0155 mg/ml/gm body weight, in 15 ppm it was 0.021 mg/ml/gm body weight and in 20ppm it was0.022 mg/ml/gm body weight.

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