Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Traditional Herbal Medicine, Stimulates Lactation with Increase in Secretion of Prolactin but not Oxytocin in the Postpartum Period

2007 ◽  
Vol 35 (02) ◽  
pp. 195-202 ◽  
Author(s):  
Takahisa Ushiroyama ◽  
Kou Sakuma ◽  
Hekiko Souen ◽  
Gou Nakai ◽  
Shouko Morishima ◽  
...  

The aim of the present investigation was to evaluate the clinical efficacy of Xiong-gui-tiao-xue-yin, a traditional Japanese herbal medicine, in stimulating lactation in the postpartum period. We enrolled 82 women who had a normal delivery in Osaka Medical College Hospital, and randomly assigned them to the following two groups: a group of 41 women who received Xiong-gui-tiao-xue-yin at a dose of 6.0 g/day (Group X), and a group of 41 women who received ergometrine (methylergometrine maleate) at a dose of 0.375 mg/day (Group E). Volume of lactation was determined daily until Day 6 postpartum. Plasma prolactin and oxytocin concentration were measured at Days 1 and 6 postpartum. The results showed that volume of lactation was significantly higher in Group X than in Group E at Days 4 ( p = 0.042), 5 ( p = 0.038), and 6 ( p = 0.046). Significant differences between Groups X and E were noted in plasma prolactin concentration at Days 1 (157.9 ± 78.2 ng/ml and 129.1 ± 64.8 ng/ml ; p = 0.037) and 6 (167.5 ± 95.4 ng/ml and 117.1 ± 53.6 ng/ml ; p = 0.0042) postpartum. On the other hand, at Day 1, oxytocin concentration was significantly higher in Group E than in Group X ( p = 0.0024). No adverse effects were observed in this study. The results of our study demonstrate the beneficial effects of Xiong-gui-tiao-xue-yin on lactation, with increase in prolactin level without increase in oxytocin level in the postpartum period. Therefore, Xiong-gui-tiao-xue-yin can be expected to improve lactation in women in the postpartum period. Further detailed bio-pharmacological studies and clinical trials to investigate the properties of this drug are warranted.

2005 ◽  
Vol 33 (01) ◽  
pp. 117-126 ◽  
Author(s):  
Takahisa Ushiroyama ◽  
Kou Sakuma ◽  
Minoru Ueki

This study was to evaluate the clinical efficacy of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Japanese traditional herbal medicine, in stabilizing postpartum psychological state. We enrolled 268 women who had a normal delivery in Osaka Medical College Hospital or its affiliated clinics and randomly assigned them to the following two groups: a group of 134 women who received Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) at a dose of 6.0 g/day and another group of 134 women without Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) (control group). We observed 2.06-fold and 1.67-fold higher incidences of depressive mood and nervousness, respectively, after delivery in the control group than in the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group. Within 3 weeks of postpartum, there was a significant difference in the incidences of maternity blues between the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group (15.7%; 21/134) and the control group (32.1%; 43/134) (p=0.0195). No adverse effects were observed in this study. The results of this study demonstrate the beneficial clinical effects of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) in stabilizing psychological state in the postpartum period. Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) can be expected to improve the mental health of women in the postpartum period and prevent maternity blues.


2021 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Sri Yunita Suraida Salat ◽  
Ahmaniyah Ahmaniyah ◽  
Emdat Suprayitno

<p><strong><em>Background:</em></strong><em> With the progress and development of medicine that is currently happening, there are still many people in Sumenep who choose Madur</em><em>ese traditional herbal medicine in an effort to prevent </em><em>and to cure disease, in the process of pregnancy, childbirth and the postpartum period.</em><em> This habit was inherited from their ancestors. Jamu is supposed to provide benefits and safe with no side effects. People in Sumenep still consuming herbal medicine during postpartum period as habit. </em><em></em></p><p><strong><em>Objectives:</em></strong><strong><em> </em></strong><em>This study aimed to describe views and opinions of postpartum mothers on the puerperal herbal medicine that they consumed during the postpartum period. </em><em></em></p><p><strong><em>Methods:</em></strong><strong><em> </em></strong><em>This study exploring the local culture, postpartum mothers’ knowledge about postpartum herbal medicine and their perception about its benefits. This study design was qualitative study with a phenomenological approach with total participants were 20 postpartum mothers and their families and 2 postpartum herbal medicine makers. Data were collected by direct observation through in-depth interviews. </em><em></em></p><p><strong><em>Results: </em></strong><em>The results showed 5 themes describing the dynamics of the Madurese traditional herbal medicine in the viewpoint of post-partum mothers, namely their reasons for consuming postpartum traditional herbal medicine, the form of the herbal traditional medicine consumed, their knowledge of postpartum herbal medicine, the benefits of postpartum traditional herbal medicine, and the mother's desire to consume the puerperal herbal medicine in the future. </em><em></em></p><p><strong><em>Conclusions:</em></strong><strong><em> </em></strong><em>It can be concluded that there was different viewpoint that described by postpartum women about consuming postpartum herbal medicine. In general, they found that postpartum herbal medicine had benefits directly in the recovery process of the postpartum period and increasing breast milk production</em>.</p>


1970 ◽  
Vol 37 (2) ◽  
pp. 52-55
Author(s):  
Sahin Akhter Jahan Habib ◽  
Sayeeda Sultana

Objective: The purpose of this study was to determine whether there is a shift in the timing of eclampsia in relation to delivery and whether traditional symptoms precede impending postpartum eclampsia. Study Design: A cross - sectional hospital - based study conducted at Gynae Unit, Dhaka Medical College Hospital from January 2006 - December 2007. Data was collected regarding the relationship of the patient's first seizure to delivery prodromal symptoms, neuroimaging studies, use of magnesium sulfate, antihypertensive therapy and follow up medical care. The analysis focused on women who had late postpartum eclampsia. Result: During the study period 178 patients were diagnosed with eclampsia. Fifty eight women (33%) had postpartum eclampsia, of which 46 women (79%) had late onset (> 48 hrs.). Interestingly only 10 of these 46 women (22%) had been previously diagnosed with preeclampsia. Forty two pt.(91%) with late postpartum eclampsia had at least 1 prodromal symptom, and 24 pt. (52%) had> 1 symptom that heralded the seizure : 40 women (87%) had headache , 20 women (44%) had visual changes, 10 (22%) had nausea or vomiting and 4 (9% ) experienced epigastric pain. Only 14 of this 42 women (33%) sought care for their symptoms , of whom 12 women (86%)had clinical evidence of preeclampsia that was not considered by the treating physician. Among all patients with eclampsia there were 14 cases of aspiration pneumonia,6 cases of pulmonary edema, 6 cases of pleural effusion 4 cases of DIC and no cases of maternal death. Conclusion: Current obstetric treatment has a resulted in a shift of eclampsia toward the postpartum period with most cases being seen as late postpartum. To reduce the rate of the postpartum eclampsia, efforts should be directed to the education of the health care providers and patients regarding the importance of prompt reporting and evaluation of symptoms of preeclampsia during the postpartum period.   DOI: 10.3329/bmj.v37i2.3594 Bangladesh Medical Journal 37(2) 2008 52-55


2018 ◽  
Vol 27 (1) ◽  
pp. 68-71
Author(s):  
Tahamina Akhter ◽  
Tabassum Ghani ◽  
Subinoy Krishna Paul ◽  
Noorjahan ◽  
Afrina Begum ◽  
...  

Introduction : when a healthy pregnant woman with no obstetric or medical risk factors goes into spontaneous labour, she should anticipate a normal delivery. But still 580, 000 women in the world die from pregnancy and childbirth each year.1 Lack of attention to postpartum care in developing countries is neglected tragedy and requires immediate attention. This study evaluates the incidence of complications of early puerperium and also focuses the specific types of complications and to detect the risk factors associated with these complications. Aims and objectives : Main aim of the study is to evaluate the common complications in early puerperium with special attention to identify the risk factors. Materials and method : This study was carried out in Dhaka Medical College Hospital and Sir Sallimullah Medical College Hospital within the period of March ’2004 to August’ 2004. Two hundred patients were selected for this study who were delivered by caesarean section in these two institutions and complications occurring within 7 days excluding first 24 hours. Patients delivered outside the hospital and with known medical diseases were excluded from this study. Detailed history taking and appropriate clinical examination and specific investigations were done for diagnosis of complications. All relevant informations was noted in prescribed data sheet and results were tabulated and statistical analysis was done. Results : Among 200 cases only 44(22%) cases had early puerperal morbidity.Most of the patients who suffered complications underwent caesarean section for obstructed labour and fetal distress who had trial at home. Many of the patients suffered from wound infection and endometritis (40.9%). Among patients, age group -<20 years suffered from wound infection(53.8%) and endometritis(45.8%) were common in age group 21-30 years. VVF was common in patients in age <20 years.Endometritis (42.2%) was maximum in women with parity 1-3 and wound infection (50%) in women with parity 4-6. Some of the patients had more than one early puerperal morbidity. Maximum number of poor class suffered from wound infection (42.4%).Early puerperal morbidity was more prevalent in women with duration of labour <18 hours and Premature rupture of membrane had relationship with endometritis (15.9%), wound infection (13.6%) and UTI (11.4%). Conclusion : Incidence of early puerperal morbidities is still quite high (22%) and many patients experiences more than one problem at a time.Long term sequelae of early puerperal infectious morbidity should not be neglected as this may interfere quality of life of a woman. J Dhaka Medical College, Vol. 27, No.1, April, 2018, Page 68-71


2020 ◽  
Vol 44 (1) ◽  
pp. 13-17
Author(s):  
Asma Ferdousi ◽  
Mainuddin Ahmad ◽  
Rasheda Samad

Background: Correct positioning and attachment play a crucial role in the successful establishment and maintenance of breast feeding. Objective of this study was to determine the effectiveness of immediate postnatal training of the mothers on their practice of proper positioning and attachment during breast feeding. Material and Methods: This one group pretest-posttest quasi-experimental study was conducted at the Department of Pediatrics and Department of Obstetrics and Gynecology of Chittagong Medical College Hospital from January 2006 to June 2006. Three hundred mothers were evaluated for breast feeding position and attachment within 6 hours following normal delivery with a questionnaire and observational checklist. Then they received training on correct positioning and attachment for successful breastfeeding. Post training effect was evaluated by assessing mothers’ practice on 7th postnatal day among 256 mothers. Pre training and post training data were analyzed with SPSS-16 and McNemar test was done to see the difference. Results: Out of 256 mothers only 22.3% were first time mother and about 40% of them had 1-2 children. Majority (84.4%) of them knew about the benefits of breast feeding though one third (36.3%) of them favored pre-lacteal feeding. Statistically significant improvement in all components of position and attachment for breast feeding was found after intervention. Conclusion: The study results showed that immediate postnatal intervention towards correct positioning and attachment were highly effective for successful breast feeding. Bangladesh J Child Health 2020; VOL 44 (1) :13-17


2003 ◽  
Vol 31 (03) ◽  
pp. 437-444 ◽  
Author(s):  
Takahisa Ushiroyama ◽  
Kou Sakuma ◽  
Hekiko Souen ◽  
Gou Nakai ◽  
Shouko Morishima ◽  
...  

The aim of the present investigation was to evaluate the clinical efficacy of Kyuki-chouketsu-in, a Japanese traditional herbal medicine, in restoring postpartum physical condition. We enrolled 171 women who had a normal delivery in Osaka Medical College Hospital or its affiliated clinics, and randomly assigned them to the following two groups: a group of 85 women who received Kyuki-chouketsu-in at a dose of 6.0 g/day (Group K), and a group of 86 women who received ergometrine (methylergometrine maleate) at a dose of 0.375 mg/day (Group E). The height of the uterine fundus, blood hemoglobin concentration and biochemical blood values were determined until day 6 postpartum. The height of the uterine fundus was significantly lower in women of Group K (8.9 ± 2.4 cm) than in those of Group E (10.5 ± 2.7 cm) on day 5 postpartum (p = 0.071). A significant difference between Groups K and E was noted in change in blood hemoglobin concentration between days 1 and 6 postpartum (4.6 ± 7.2% in Group K; -1.57 ± 7.3% in Group E). Significant differences between Groups K and E were noted in decrease in serum C-reactive protein (CRP) concentration and increases in serum total protein (TP) and albumin concentrations between days 1 and 6 postpartum. No adverse effects were observed in this study. The results of our study demonstrate the beneficial effects of Kyuki-chouketsu-in on physical recovery in the postpartum period. Kyuki-chouketsu-in can be expected to improve the health of women in the postpartum period. Biopharmacological research and clinical trials to investigate the properties of this drug in detail are warranted.


2013 ◽  
Vol 1 (2) ◽  
pp. 141
Author(s):  
Hui-Shuang Yeh ◽  
Kou-Joong Lin ◽  
Chun-Kuang Chou ◽  
Tu-Fa Lien ◽  
Chia-Mo Liao

This study was to investigate the effect of adding Chinese traditional herbal medicine complex in diets on the carcass quality of the pigs. 100 crossbred growing pigs (LYD) (44.5 ± 1.63 kg) were randomly divided into 5 groups including supplementation 0.0, 0.3, 0.5 and 0.7% Chinese herbal medicine complex (CHM), and antibiotics groups (chlortetracycline 100 ppm and oxytetracycline 100 ppm) with four replicates. Experimental results indicated that meat polyphenol and flavonoids content in the group with 0.7% CHM addition, and the Hunter a value in the 0.5% and 0.7% CHM groups was better than those of the control and antibiotics groups (P<0.05). The panel evaluation revealed that the 0.7% CHM supplemented group had better values for juiciness and overall-acceptance than the control and antibiotics groups (P<0.05). In conclusion, supplementation of Chinese herbal medicine complex in pig’s diet had beneficial effects on meat quality, and 0.7% CHM addition had the best results for meat quality.


Author(s):  
Sadiq Unnisa ◽  
Poornima M. S.

Background: In Obstetrics it is traditional concept that fetal head engagement occurs by 38 weeks in primigravida. Unengaged head in primigravida has been considered a possible sign of cephalo pelvic disproportion. It is associated with higher risk of cervical dystocia, which has led to increased rate of caesarean section with its financial implication and future restriction of family size. Labour is prolonged, the duration of both latent and active phase increases, due to improper fitting high fetal head.Methods: The prospective descriptive study was conducted at the Yenepoya Medical College hospital OBG Department.  Study population included were 75 primi gravidas with unengaged head at term. Details of labour were noted down.  Augmentation was done with oxytocin and dose of oxytocin was titrated . CTG was used to monitor fetal heart.  Emergency LSCS was performed in patients with fetal distress or non-progress of labour.  In case of vagina delivery, duration of 1st and 2nd stage, APGAR score at 1 and 5 minutes, and birth weights were recorded.Results: Of the 75 primigravida 66.66% were in the age group of 21-25yrs.  Majority of the women were of 39-40 weeks (42.66%) of gestation. Common causes of unengaged head was deflexed head in 15 (20%) CPD in 11 (14.66%), loops of cord around neck in 8 (10.66%), polyhydramnios in 2(2.66%), placenta previa type-I and II  : anterior in 5 (6.66%) 8 patients were with occipito posterior position.  No cause could be identified in 27 cases (36%). Vaginal delivery occurred in 68% and LSCS in 32%.Conclusions: Unengaged head in primi gravida with spontaneous onset of labour is not an indication for LSCS. The attitude of watchful expectancy and timely intervention especially in those cases in which no significant etiological factor is found, the chances of vaginal birth increase there by reducing maternal land foetal morbidity.


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