scholarly journals ISMAC: An Intelligent System for Customized Clinical Case Management and Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Mingyu You ◽  
Chong Chen ◽  
Guo-Zheng Li ◽  
Shi-Xing Yan ◽  
Sheng Sun ◽  
...  
Keyword(s):  
Chinese Culture ◽  
Clinical Case ◽  
Intelligent System ◽  
Medical Knowledge ◽  
Feature Reduction ◽  
Arduous Task ◽  
Intelligent Analysis ◽  
Retrieval Mechanism ◽  
Treatment Characteristic ◽  
Clinical Cases

Clinical cases are primary and vital evidence for Traditional Chinese Medicine (TCM) clinical research. A great deal of medical knowledge is hidden in the clinical cases of the highly experienced TCM practitioner. With a deep Chinese culture background and years of clinical experience, an experienced TCM specialist usually has his or her unique clinical pattern and diagnosis idea. Preserving huge clinical cases of experienced TCM practitioners as well as exploring the inherent knowledge is then an important but arduous task. The novel system ISMAC (Intelligent System for Management and Analysis of Clinical Cases in TCM) is designed and implemented for customized management and intelligent analysis of TCM clinical data. Customized templates with standard and expert-standard symptoms, diseases, syndromes, and Chinese Medince Formula (CMF) are constructed in ISMAC, according to the clinical diagnosis and treatment characteristic of each TCM specialist. With these templates, clinical cases are archived in order to maintain their original characteristics. Varying data analysis and mining methods, grouped as Basic Analysis, Association Rule, Feature Reduction, Cluster, Pattern Classification, and Pattern Prediction, are implemented in the system. With a flexible dataset retrieval mechanism, ISMAC is a powerful and convenient system for clinical case analysis and clinical knowledge discovery.

Combined urogenital abnormalities of development and the formation of reproductive health in girls

2021 ◽  
Vol 25 (6) ◽  
pp. 99-105
Author(s):  
Yu. Yu. Chebotareva ◽  
G. M. Letifov ◽  
M. A. Rodina
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Reproductive Health ◽  
Tract Infection ◽  
Clinical Case ◽  
Recurrent Urinary Tract Infection ◽  
Practical Importance ◽  
Type I ◽  
Functional Features ◽  
Clinical Cases

BACKGROUND. Anomalies in the development of the uterus and vagina in some cases are combined with defects of the urinary tract. Therefore, the analysis of clinical situations associated with combined urogenital pathology in girls is of current and practical importance.THE AIM: to assess the state of reproductive health in girls with reproductive anomalies, renal agenesis, and other diseases of the urinary tract.PATIENTS AND METHODS. The study was conducted in 5 adolescent girls, including 3 patients with kidney agenesis, 1 patient with dysmetabolic nephropathy and nephroptosis, and 1 patient with recurrent urinary tract infection. In the analysis of clinical cases, the anatomical and functional features of the reproductive system are presented.RESULTS. The first 3 clinical cases are associated with the presence of kidney agenesis in the girl. In 1 clinical case, the clinic of the Mayer-Rokitansky-Kuester-Hauser syndrome (SMRKH) type II, including aplasia of the uterus and vagina and renal malformation, is presented. In clinical case 2, it was shown that modern transabdominal ultrasound examination of the pelvic organs, similar to MRI, can reveal the Herlin-Werner-Wunderlich syndrome. Agenesis of the kidney is one of the manifestations of trisomy of 22 pairs of chromosomes, which was noted in a patient from 3 clinical cases. 4 clinical cases is associated with the fact that kidney pathology, including nephroptosis, dysmetabolic nephropathy, can be combined with impaired sexual development. In 5 clinical case, type I SMRCC was described in a patient with recurrent urinary tract infection.CONCLUSION. Congenital malformations of the female genital organs are a rare pathology that requires special attention. Due to insufficient data concerning the mechanism of development of malformations of the genitourinary system, this problem requires further detailed study.

Intelligent system for university legal education

2020 ◽  
pp. 1-12
Author(s):  
Hesheng Xu
Keyword(s):  
Personal Development ◽  
Intelligent System ◽  
Legal Education ◽  
Application Rate ◽  
Traditional Teaching ◽  
Rate System ◽  
Operation Process ◽  
Intelligent Analysis ◽  
The University ◽  
Study Designs

University legal education is of great significance to the personal development and social stability of college students. At present, there are certain problems in the traditional teaching system, which has led to inefficient university legal education. In order to improve the legal teaching effect of the university, based on machine learning and neural networks, this paper integrates and optimizes the original hardware and software and operation process, and further highlights the functions of interconnection and sharing, automatic sensing, real-time recording, interactive feedback, dynamic supervision, and intelligent analysis, which greatly facilitates the evaluation of teaching at all levels. In particular, this study uses big data technology to conduct an intelligent analysis of data completeness, multimedia application rate, system execution, and average test scores, and scientifically evaluates the implementation of basic-level education systems and the effectiveness of education, which can effectively solve the problems of quantitative formalization and qualitative subjectivity of current education evaluation from a technical level. In addition, this study designs a control experiment to analyze the system performance. The research results show that the model proposed in this paper has a certain effect.

scholarly journals PARANEOPLASTIC SYNDROMES IN THE PRACTICE OF A NEUROLOGIST (CLINICAL CASES)

2019 ◽  
pp. 44-51
Author(s):  
N. L. Bozhenko ◽  
M. I. Bozhenko ◽  
S. Y. Кyrylyuk ◽  
I. M. Bozhenko ◽  
A. O. Tyutko
Keyword(s):  
Differential Diagnosis ◽  
Clinical Case ◽  
Careful Analysis ◽  
Paraneoplastic Syndromes ◽  
Systemic Effects ◽  
Malignant Diseases ◽  
The Future ◽  
Clinical Cases

Paraneoplastic syndromes are the rare states caused by a change in the immune system's response to neoplasms. These include non-metastatic systemic effects that accompaniy malignant diseases. Diagnosis of these syndromes has some difficulties. In this article clinical cases of patients with paraneoplastic syndromes are analyzed and differential diagnosis is performed. Careful analysis of each clinical case is extremely important for the accumulation of experience, improvement of diagnostics and avoiding mistakes in the future.

scholarly journals Objective Structured Clinical Examination’s adaptation for final evaluation of the curricular component “Semiological Bases”

2019 ◽  
Vol 3 (1) ◽  
pp. 61
Author(s):  
Fernando Muti Carvalho ◽  
Marta Silva Menezes ◽  
Iêda Maria Barbosa Aleluia ◽  
Humberto Castro Lima Filho ◽  
Ana Veronica Mascarenhas Batista ◽  
...  
Keyword(s):  
Medical Student ◽  
Medical Students ◽  
Physical Examination ◽  
Clinical Case ◽  
Medical Knowledge ◽  
Clinical Findings ◽  
Whole Process ◽  
Medical Student Learning ◽  
Practical Exam ◽  
De Medicina

BACKGROUND: The combination of both physiological knowledge of a variety of sistems and the clinical findings it is of extreme relevance to the medical student learning process. The proposal of a simulated enviroment, with clinical data collection and regular physical examination, is crucial to this process. The Semiological bases of Escola Bahiana de Medicina e Saúde Pública module, used by the OSCE’s 4th semester medical students, capacitate them for such means. SUMMARY OF WORK: The evaluation logistic was divided into two segments: the first one was made through a theorical exam with close questioning, exhibiting images and videos, but also containing an open-ended question requesting a construction of a fictional clinical case; in the second one it was applied a practical exam segmented by different fields of medical knowledge (neurological, cardiovascular and respiratory/abdomen), with the evaluation of 120 students and followed by the teacher’s feedbacks at the conclusion of each field exam. SUMMARY OF RESULTS: The experience was important, however, it is notable the need for a complex management and understanding of the evaluational process. Discussion between students and teachers happened in behalf of the development of such proposal. CONCLUSIONS: The application of theorical exams throughout the semester combined with a practical exam (the OSCE) at the conclusion of the curricular component Bases Semiológicas had significant weight to the whole process.

scholarly journals Physio Kundalini Syndrome: A Case Report

2019 ◽  
Vol 2 (3) ◽  
pp. 60-64
Author(s):  
Jose Carvalho Ramos Alexandre ◽  
Keyword(s):  
Case Report ◽  
Psychotic Disorder ◽  
Clinical Case ◽  
Health Problems ◽  
Medical Intervention ◽  
Spiritual Practices ◽  
Common Elements ◽  
Western Countries ◽  
Yoga Meditation ◽  
Clinical Cases

With the spread of yoga, meditation, and other Eastern spiritual practices in Western countries, clinical cases of “physio kundalini syndrome” have begun to emerge. In this article I presented a case that, despite having common elements with a psychotic disorder, can be considered a typical clinical case of awakening of kundalini, since the patient was apparently able to solve his health problems without any medical intervention and says he is perfectly integrated into the community.

scholarly journals Challenges of the differential diagnosis between the subtypes of the junctional epidermolysis bullosa: presentation of two clinical cases

2019 ◽  
Vol 47 (1) ◽  
pp. 83-93
Author(s):  
Yu. Yu. Kotalevskaya ◽  
N. M. Marycheva
Keyword(s):  
Differential Diagnosis ◽  
Epidermolysis Bullosa ◽  
Skin Disease ◽  
Clinical Case ◽  
Molecular Genetic ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Junctional Epidermolysis Bullosa ◽  
Reliable Determination ◽  
Clinical Cases

Background: Epidermolysis bullosa (EB) is a rare hereditary skin disease. It is subdivided into EB simplex (EBS), junctional EB (JEB), dystrophic EB (DEB) and Kindler syndrome. JEB is diagnosed in 2 per 1,000,000 of the population. There are few descriptions of clinical JEB cases in the literature. Clinical diagnosis of JEB and its subtypes is a challenge, especially in the early age. The paper presents 2 clinical cases of JEB in patients of the West Slavonic origin. Clinical case No. 1 was a girl of Ukrainian ethnicity, with confirmed definitive diagnosis of severe generalized JEB. Molecular genetic tests identified mutations of the LAMA3 gene that had not been described previously. The patient died at the age of 24 months from acute respiratory failure. When the patient was alive, her EB type and subtype was not possible to identify, because she had a combination of clinical manifestations typical for various JEB subtypes. Despite such symptoms as hoarse voice, stenoses, granulation tissue of typical location, laryngeal granulations, the girl was steadily gaining weight, with some periods of relative stabilization of the skin disease; she also had longer life longevity than was common for patients with severe generalized JEB. All this made a precise diagnosis difficult. Clinical case No. 2: an ethnic Russian boy with non-classified JEB. Molecular genetic testing helped to identify a homozygote mutation in the LAMA3 gene that had not been previously described; reliable determination of the subtype was not possible. The patient had mixed clinical manifestation similar both to generalized severe JEB and to laryngo-onycho-cutaneous (LOC) syndrome. During his lifetime, the patient was clinically diagnosed with Hallopeau acrodermatitis and LOC syndrome. The differential diagnostic problems were associated with the presence of signs not typical for each of the subtypes. Significant life longevity of the proband is not characteristic for severe generalized JEB (at the time of the publication the patient is 13 years old), whereas for LOC syndrome the absence of eye involvement is not typical, as well as severe laryngeal involvement at adolescence.Conclusion: Detailed descriptions of phenotype of JEB subtypes including rare and minimal clinical signs can be useful to study the clinical manifestations and natural course of the disease, including its differential diagnosis.

scholarly journals 1714. Testing a Novel Clinical Surveillance Case Definition for Invasive Mold Infections

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S628-S629
Author(s):  
Karlyn Beer ◽  
Hilary Kelly ◽  
Rebekah Blakney ◽  
Taylor Chambers ◽  
Lewis Perry ◽  
...  
Keyword(s):  
Clinical Case ◽  
Case Definition ◽  
Antifungal Treatment ◽  
Emerging Infections ◽  
Dimorphic Fungi ◽  
Clinical Surveillance ◽  
Immunosuppressed Patients ◽  
Invasive Mold Infections ◽  
Clinical Case Definition ◽  
Clinical Cases

Abstract Background Invasive mold infections (IMI) such as aspergillosis and mucormycosis are often fatal among immunosuppressed patients and have caused high-profile outbreaks. Surveillance for IMI is challenging because distinguishing a case from colonization or contamination is complex. The established case definition, Mycoses Study Group (MSG) criteria, lacks sensitivity. Because the need for surveillance remains, we designed a pilot IMI surveillance system within the Georgia Emerging Infections Program. Here, we describe cases identified through this system, using both the MSG criteria and a novel, more sensitive clinical case definition. Methods To identify potential IMI cases, we captured fungal cultures positive for mold, histopathology specimens with evidence of fungal tissue invasion, and positive galactomannan results within a 60-day window at three large hospitals in Atlanta during March 2017–2018. We excluded dimorphic fungi and hair and nail specimens. Of 194 potential cases, we selected 24 for complete medical chart review. Two physicians classified cases as proven, probable, or non-case according to MSG criteria. Cases that partially met MSG probable criteria and included antifungal treatment were classified as clinical cases; definitions were mutually exclusive (Figure 1). Results Of 24 potential IMI cases, 16 (66%) met an IMI case definition, including 5 proven, 2 probable and 9 clinical cases. Inter-rater agreement was 92%., Most (5/7) MSG cases involved Aspergillus and were more likely to have cancer, a transplant, or other immunosuppression compared with clinical cases (Figure 2 and 3). Clinical cases included conditions not specified in MSG criteria, including burns (1), wounds (1) or eye (4) infections. MSG and clinical cases more often had antifungal treatment (16/16 vs. 1/8) or died (4/16 vs. 0/8) compared with non-cases. Conclusion In this preliminary analysis of potential IMI cases, most represented true invasive infections, indicating effective exclusion of most colonization. Most of the 16 cases were classified as clinical, however, and would have been missed in a system relying on the MSG criteria alone. Results suggest that a less-specific clinical case definition incorporating antifungal treatment may improve the sensitivity and utility of IMI surveillance. Disclosures All authors: No reported disclosures.

scholarly journals Ontology-Oriented Diagnostic System for Traditional Chinese Medicine Based on Relation Refinement

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Peiqin Gu ◽  
Huajun Chen ◽  
Tong Yu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Medical Knowledge ◽  
Diagnostic System ◽  
Syndrome Differentiation ◽  
Diagnosis System ◽  
Knowledge Based ◽  
Interpretable Model ◽  
Online Web ◽  
Clinical Cases

Although Chinese medicine treatments have become popular recently, the complicated Chinese medical knowledge has made it difficult to be applied in computer-aided diagnostics. The ability to model and use the knowledge becomes an important issue. In this paper, we define the diagnosis in Traditional Chinese Medicine (TCM) as discovering the fuzzy relations between symptoms and syndromes. An Ontology-oriented Diagnosis System (ODS) is created to address the knowledge-based diagnosis based on a well-defined ontology of syndromes. The ontology transforms the implicit relationships among syndromes into a machine-interpretable model. The clinical data used for feature selection is collected from a national TCM research institute in China, which serves as a training source for syndrome differentiation. The ODS analyzes the clinical cases to obtain a statistical mapping relation between each syndrome and associated symptom set, before rechecking the completeness of related symptoms via ontology refinement. Our diagnostic system provides an online web interface to interact with users, so that users can perform self-diagnosis. We tested 12 common clinical cases on the diagnosis system, and it turned out that, given the agree metric, the system achieved better diagnostic accuracy compared to nonontology method—92% of the results fit perfectly with the experts’ expectations.

scholarly journals Intelligent Analysis of Computer-Aided Garment Design CAD Based on Virtual Reality Model for Surplus Fabric Removal and Reuse without Segmentation of Cutting Pieces

2022 ◽  
Vol 2022 ◽  
pp. 1-13
Author(s):  
Tanqiu Wang
Keyword(s):  
Virtual Reality ◽  
Intelligent System ◽  
Design Element ◽  
Cad System ◽  
Design Time ◽  
Intelligent Analysis ◽  
Computer Aided ◽  
Garment Design ◽  
Virtual Reality Model

For the purpose of improving the efficiency of garment design, the computer-aided garment design virtual reality (VR) model for surplus fabric removal and reuse without segmentation of cutting pieces is analyzed in this paper to provide the architecture of the computer-aided garment design CAD system. The form of dividing the garment into multiple types of nonsegmented pieces is adopted so that each nonsegmented piece stands for a complete design element unit. Based on this structure, the computer analysis of garment design based on CAD can be connected at a deeper level, which will not only improve the design efficiency of new garments but also reduce the design time at the client terminal and enhance the quality of the design. Through the experimental operation of prototypes, it is verified that the intelligent system proposed in this paper can implement the design of prototypes quickly and effectively.

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