scholarly journals Climate Responsive Design Simulation and Modelling for Industrial Heritage

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Manuel V. Castilla
Keyword(s):  
Solar Radiation ◽  
Sustainable Design ◽  
Common Denominator ◽  
Industrial Heritage ◽  
Standard Design ◽  
Different Types ◽  
Responsive Design ◽  
Design Characteristics ◽  
Cooling Loads ◽  
New Strategies

The control of solar radiation is a basic dimension of modern design in all different types of constructions. Many architects have recently observed that different phases of sustainable design require a set of calculations and simulations that are necessary as a new standard design. The valuable contributions to the process of sustainable design has a common denominator: solar radiation and comfort. In this way, motivated by all these new strategies and concepts, the large number of papers published suggests that the work has not been finished. This work provides an illustration of the Atarazanas regarding its climate responsiveness, focusing specifically on daylighting, shading, heat gain, and cooling loads. The objective is to assess the design of the Reales Atarazanas de Sevilla (Seville Royal Dockyards) to quantify how it is impacted by solar insolation and to provide insights about design characteristics that influence efficiency and conservation.

DEFORMATION AND CRACKING OF THE PLATFORM JOINT OF THE PREFABRICATED-MONOLITHICRC BUILDING FRAME

2020 ◽  
Vol 90 (4) ◽  
pp. 38-47
Author(s):  
VL.I. KOLCHUNOV ◽  
◽  
D.V. MARTYNENKO ◽  
Keyword(s):  
Reinforced Concrete ◽  
Plane Stress State ◽  
Hollow Core ◽  
Finite Element Scheme ◽  
Element Scheme ◽  
Joint Structure ◽  
Numerical Studies ◽  
Distributed Load ◽  
Different Types ◽  
Design Characteristics

A computational model and the results of numerical studies of the structure of a platform joint in a reinforced concrete precast-monolithic frame of a building from panel-frame elements of industrial production are presented. Modeling of the plane stress state of the joint structure is carried out by a finite element scheme, using finite elements of different types and a nonlinear law of deformation to determine the design characteristics of reinforced concrete. The parameters of deformation of the platform joint structure at different loading levels, including stage-by-stage cracking and destruction, have been determined. The schemes of distribution and stress concentration zones in the characteristic sections of the platform joint are established when the distributed load is transferred from the frame of the panel-frame to the hollow-core floor panels and concrete for embedding the joint in the presence of a cavity in the frame frame for centering elements.

scholarly journals Human Granulosa Cells—Stemness Properties, Molecular Cross-Talk and Follicular Angiogenesis

Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1396
Author(s):  
Claudia Dompe ◽  
Magdalena Kulus ◽  
Katarzyna Stefańska ◽  
Wiesława Kranc ◽  
Błażej Chermuła ◽  
...  
Keyword(s):  
Stem Cells ◽  
Granulosa Cells ◽  
Polycystic Ovary ◽  
Ovarian Follicle ◽  
Cumulus Cells ◽  
Ovary Syndrome ◽  
Different Types ◽  
Metabolite Exchange ◽  
Reproductive Techniques ◽  
New Strategies

The ovarian follicle is the basic functional unit of the ovary, comprising theca cells and granulosa cells (GCs). Two different types of GCs, mural GCs and cumulus cells (CCs), serve different functions during folliculogenesis. Mural GCs produce oestrogen during the follicular phase and progesterone after ovulation, while CCs surround the oocyte tightly and form the cumulus oophurus and corona radiata inner cell layer. CCs are also engaged in bi-directional metabolite exchange with the oocyte, as they form gap-junctions, which are crucial for both the oocyte’s proper maturation and GC proliferation. However, the function of both GCs and CCs is dependent on proper follicular angiogenesis. Aside from participating in complex molecular interplay with the oocyte, the ovarian follicular cells exhibit stem-like properties, characteristic of mesenchymal stem cells (MSCs). Both GCs and CCs remain under the influence of various miRNAs, and some of them may contribute to polycystic ovary syndrome (PCOS) or premature ovarian insufficiency (POI) occurrence. Considering increasing female fertility problems worldwide, it is of interest to develop new strategies enhancing assisted reproductive techniques. Therefore, it is important to carefully consider GCs as ovarian stem cells in terms of the cellular features and molecular pathways involved in their development and interactions as well as outline their possible application in translational medicine.

scholarly journals The Effects of Roadside Woody Vegetation on the Surface Temperature of Cycle Paths

Land ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 483
Author(s):  
Nikola Žižlavská ◽  
Tomáš Mikita ◽  
Zdeněk Patočka
Keyword(s):  
Solar Radiation ◽  
Surface Temperature ◽  
Well Being ◽  
Road Surface ◽  
Woody Vegetation ◽  
Surface Model ◽  
Main Hypothesis ◽  
Roadside Vegetation ◽  
Different Types ◽  
Aerial Vehicle

The article is on the effects of woody vegetation growing on the roadside on the temperature of the surface of cycle paths. The main hypothesis of the study is that vegetation has the effect of lowering the temperature of the surroundings in its shadow and thus improves the comfort of users of cycle paths in the summer months. The second hypothesis is to find out which type of road surface is most suitable for the thermal well-being of users. This goal was achieved by measuring the temperature of selected locations on cycle paths with different types of construction surfaces with nearby woody vegetation using a contactless thermometer over several days at regular intervals. The positions of the selected locations were measured using GNSS and the whole locality of interest was photographed using an unmanned aerial vehicle (UAV), or drone, and subsequently a digital surface model (DSM) of the area was created using a Structure from Motion (SfM) algorithm. This model served for the calculation of incident solar radiation during the selected days using the Solar Area Graphics tool with ArcGIS software. Subsequently, the effect of the shade of the surrounding vegetation on the temperature during the day was analysed and statistically evaluated. The results are presented in many graphs and their interpretation used to evaluate the effects of nearby woody vegetation and the type of road surface on the surrounding air temperature and the comfort of users of these routes. The results demonstrate the benefits of using UAVs for the purpose of modelling the course of solar radiation during the day, showing the effect of roadside vegetation on reducing the surface temperature of the earth’s surface and thus confirming the need for planting and maintaining such vegetation.

scholarly journals Effects of Aerosols and Clouds on the Levels of Surface Solar Radiation and Solar Energy in Cyprus

2021 ◽  
Author(s):  
Ilias Fountoulakis ◽  
Panagiotis Kosmopoulos ◽  
Kyriakoula Papachristopoulou ◽  
Panagiotis-Ioannis Raptis ◽  
Rodanthi-Elisavet Mamouri ◽  
...  
Keyword(s):  
Solar Radiation ◽  
Solar Energy ◽  
Renewable Energy Sources ◽  
Financial Loss ◽  
Low Latitude ◽  
High Quality ◽  
Surface Solar Radiation ◽  
Satellite Retrievals ◽  
Different Types ◽  
Fine Resolution

Cyprus plans to drastically increase the share of renewable energy sources from 13.9% in 2020 to 22.9% in 2030. Solar energy can play a key role in the effort to fulfil this goal. The potential for production of solar energy over the island is much higher than most of European territory because of the low latitude of the island and the nearly cloudless summers. In this study, high quality and fine resolution satellite retrievals of aerosols and dust, from the newly developed MIDAS climatology, as well as information for clouds from CMSAF are used in order to quantify the effects of aerosols, dust, and clouds on the levels of surface solar radiation (SSR) and the corresponding financial loss for different types of installations for production of solar energy. An SSR climatology has been also developed based on the above information. Ground-based measurements were also incorporated to study the contribution of different species to the aerosol mixture and the effects of day-to-day variability of aerosols on SSR. Aerosols attenuate 5 – 10% of annual GHI and 15 – 35% of annual DNI, while clouds attenuate ~25 – 30% and 35 – 50% respectively. Dust is responsible for 30 – 50% of the overall attenuation by aerosols.

Modern Rebels?

2014 ◽  
Author(s):  
Niall Whelehan
Keyword(s):  
United States ◽  
Nineteenth Century ◽  
The United States ◽  
Irish Nationalism ◽  
Revolutionary Violence ◽  
Different Types ◽  
Revolutionary Movements ◽  
New Strategies

This chapter explores different types of revolutionary violence adopted by Irish nationalists in Ireland and the Irish diaspora in the nineteenth century. Due to the limitations of past rebellions, militant nationalists sought to adopt new strategies that embraced science and modernity. This led to the adoption of an urban-bombing campaign in the 1880s carried out by networks of militants across Ireland, Europe, and the United States. Far from being peculiar to Irish nationalism, these violent strategies found parallels with other revolutionary movements in Europe and the United States.

Contribution for the Study of New Pathogenic Indicators Removal from W.S.P. in Portugal

1991 ◽  
Vol 24 (2) ◽  
pp. 381-386 ◽  
Author(s):  
M. J. Nascimento ◽  
J. S. Oliveira ◽  
L. Oliveira ◽  
J. T. Mexia
Keyword(s):  
Solar Radiation ◽  
Climatic Factor ◽  
Climatic Parameters ◽  
Faecal Coliforms ◽  
Different Types ◽  
Microbial Removal ◽  
Pathogens Removal ◽  
Faecal Streptococci

In the control of pathogens removal in W.S.P. in Portugal, other indicators than the classic ones were used to quantify die-off kinetics (Faecal coliforms, Faecal Streptococci, Clostridiumperfringens, Pseudomonasaeruginosa and Heterotrophies). The influence of climatic parameters (temperature, precipitation, solar radiation) in that kinetics was studied, different equations being tested to express relationships existing among climatic parameters and microbial removal in different types of ponds. The existence of significant correlations among these factors and parameters was concluded, as well as the dominance of certain models to quantify these relationships, differing according to the microorganisms considered, the type of lagoon and the climatic factor (θ) studied.

scholarly journals Cancer Nano-Immunotherapy from the Injection to the Target: The Role of Protein Corona

2020 ◽  
Vol 21 (2) ◽  
pp. 519
Author(s):  
Idoia Mikelez-Alonso ◽  
Antonio Aires ◽  
Aitziber L. Cortajarena
Keyword(s):  
Protein Corona ◽  
Biological Properties ◽  
Immune Reactivity ◽  
Target Tissue ◽  
Physiological Conditions ◽  
Different Types ◽  
Cancer Remission ◽  
New Strategies

Immunotherapy has become a promising cancer therapy, improving the prognosis of patients with many different types of cancer and offering the possibility for long-term cancer remission. Nevertheless, some patients do not respond to these treatments and immunotherapy has shown some limitations, such as immune system resistance or limited bioavailability of the drug. Therefore, new strategies that include the use of nanoparticles (NPs) are emerging to enhance the efficacy of immunotherapies. NPs present very different pharmacokinetic and pharmacodynamic properties compared with free drugs and enable the use of lower doses of immune-stimulating molecules, minimizing their side effects. However, NPs face issues concerning stability in physiological conditions, protein corona (PC) formation, and accumulation in the target tissue. PC formation changes the physicochemical and biological properties of the NPs and in consequence their therapeutic effect. This review summarizes the recent advances in the study of the effects of PC formation in NP-based immunotherapy. PC formation has complex effects on immunotherapy since it can diminish (“immune blinding”) or enhance the immune response in an uncontrolled manner (“immune reactivity”). Here, future perspectives of the field including the latest advances towards the use of personalized protein corona in cancer immunotherapy are also discussed.

Multifunctionalized carbon nanotubes as advanced multimodal nanomaterials for biomedical applications

2012 ◽  
Vol 1 (1) ◽  
pp. 17-29 ◽  
Author(s):  
Giuseppe Lamanna ◽  
Alessia Battigelli ◽  
Cécilia Ménard-Moyon ◽  
Alberto Bianco
Keyword(s):  
Carbon Nanotubes ◽  
Diagnostic Imaging ◽  
Biomedical Applications ◽  
Therapeutic Modalities ◽  
Different Types ◽  
Therapeutic Properties ◽  
New Strategies ◽  
Combine Diagnosis

AbstractThe increasing importance of nanotechnology in the field of biomedical applications has encouraged the development of new nanomaterials endowed with multiple functions. Novel nanoscale drug delivery systems with diagnostic, imaging and therapeutic properties hold many promises for the treatment of different types of diseases, including cancer, infection and neurodegenerative syndromes. Functionalized carbon nanotubes (CNTs) are one of the most recent type of nanomaterial developed in biomedicine as they can be designed and imparted with multimodal capabilities. Indeed, the possibility of inserting different functionalities on CNTs is opening the possibility to exploit them on new strategies that combine diagnosis with improved therapeutic efficacies. In this review, we describe the different approaches that have been recently developed to generate multifunctionalized CNTs for biomedical applications. In particular, covalent and non-covalent double and triple functionalization methods are discussed, putting in evidence their use in vitro and in vivo and highlighting the advantages and the drawbacks of these new systems. Preclinical studies have demonstrated that multifunctional CNTs are highly promising when combining diagnostic, imaging and therapeutic modalities.

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