scholarly journals Portable Handheld Slit-Lamp Based on a Smartphone Camera for Cataract Screening

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Shenming Hu ◽  
Hong Wu ◽  
Xinze Luan ◽  
Zhuoshi Wang ◽  
Mary Adu ◽  
...  

Purpose. As part of plans to provide help to people in remote and poor areas who have no medical resources, a portable slit-lamp based on a smartphone was proposed. This would help in early screening of cataract diseases. Methods. This means a microlens is designed that would work with a phone’s camera. The phone’s photo taking function is used in capturing the image of the eyes lens to replace the observation system of the desktop slit-lamp. A simplified slit light band was designed. In order for the light source part to meet the portable requirements of the slit-lamp, the adjustable and diffused light functions of the ligaments were removed in this design. Furthermore, the images collected by the smartphone are uploaded to the deep learning cataract screening system, which can achieve real-time and effective screening of cataract. Results. Unlike the desktop slit-lamp, which needs skilled personnel to operate, this device can be easily operated by less-skilled or inexperienced doctors. This eliminates the concerns of inaccurate diagnosis based on the use of unskilled professionals. Due to the portability, ease of use, and simplicity in obtaining crystal images of this device, it serves as a promising platform for nonhospital screening and telemedicine. Conclusions. In this paper, we invented a small portable device for screening cataract. This device is to make screening and diagnosis of cataract in remote areas very fast and effective. It will also solve the problem of inadequate specialized doctors and equipment in those areas as well. Translational Relevance. Smartphones can be used with portable slit-lamps to capture the images of the lens.

2021 ◽  
Author(s):  
Diego Aviles ◽  
David Warshal ◽  
Lauren Krill ◽  
Olga Ostrovsky

Extracellular vesicles (EVs) are a varied group of cell-derived, microscopic, fluid-filled pouches released from cells into neighboring microenvironments that are quickly gaining recognition as a potentially powerful tool against epithelial ovarian cancer (EOC). Recent studies show that not only do EVs play an integral part in the development of cancer through intercellular communication, cell survival, and immune modulation but also may assist with early diagnosis and improved treatments. EOC currently has few effective screening options for early detection of this disease; and, therefore, it is detected at an advanced stage where it is more likely to recur, develop chemoresistance, and ultimately become fatal. Newer research has evaluated EVs as biomarkers for early screening and diagnosis and as novel targets for treatment of EOC. Moreover, EVs are possible targets for novel immunomodulatory therapies to directly target cancer cells or make cancer cells more susceptible to other treatment modalities. Therefore, EVs present an exciting, promising approach which may improve clinical outcome for EOC patients.


2017 ◽  
Vol 9 (S11) ◽  
pp. S1218-S1226
Author(s):  
Kai-Ping Zhang ◽  
Bella Poon

The objective of the paper was to evaluate developed screening tools on autism students’ as early detection detect early signs especially on visual for ASD children. The outcomes of early intervention in ASD can be improved but it depends types of the treatment. Method of collecting data was using tool, observation and interview. In design, flowchart and storyboard are produced. While in development stage, learning media and materials are presented with visualization in the form of sound, text, videos and pictures. The results of this study are a positive score and feedback from children with ASD. They are easy to focus in using this tool instead of conventional screening tool. The students really attract to something that related to technology. However, the suggestion of a screening for ASD when concerning from their parents or family. The quality of the instruments and screening procedure are the challenges faced during the process. The advantages of early screening and detection among ASD is very to avoid parents unnecessary worry among parents.


Author(s):  
Helena Gil-Campesino ◽  
◽  
Laura Sante ◽  
Enrique Callejas Castro ◽  
María Lecuona

Objective. The aim of the study was to evaluate a complementary screening system for the detection of sexually transmitted infections in patients with sterile pyuria. Material and methods. A prospective study was conducted using Real-time multiplex qPCR in 300 consecutive urine samples with data on sterile pyuria. STI prevalence and patient epidemiological data were analyzed. Results. A total of 29 positive cases (9.67%) were found: 16 Chlamydia trachomatis, 5 Mycoplasma genitalium, 5 Trichomonas vaginalis and 3 co-infections. The group with sexually transmitted infections was mainly composed of women (65.5%), of which one third was pregnant. Conclusion. This study presents an effective screening system for the detection of sexually transmitted infections that can be integrated into the laboratories’ work routine.


2021 ◽  
Vol 3 (1) ◽  
pp. 166-171
Author(s):  
Siti Annisa Nur Fathia

The Postpartum period is characterized by overwhelming emotional, biological, physical, and social changes. It needs significant personal and interpersonal adaptation, especially in primigravida. Pregnant women and their families are colored by the joyful arrival of a new baby in the postpartum period. But also, the mother in the postpartum period can be vulnerable to a range of postpartum psychosis. Postpartum psychosis is one of serious mental disorder that can result in adverse consequences such as suicide. Suicide is rare during the acute episode, but the rate is high later in the mother’s life and first-degree relatives. Psychosis postpartum is frequently under‑diagnosed, it needs early screening and diagnosis to determine the appropriate treatment as a mandatory part of postpartum care.


The key to successful management of any disease is its timely screening and diagnosis. Undetected and uncontrolled diabetes increases the chances of oral diseases, especially periodontitis. Chronic periodontitis and diabetes are two mutually related pathologies and are known to aggravate each other’s pathological effect. Since diabetes acts as an important risk factor for periodontal inflammation, it is essential to screen blood glucose levels to detect diabetes in patients presenting with chronic periodontitis. Periodontal inflammation produces ample gingival bleeding (gingival crevicular blood: GCB) during examination by the periodontal probe, which could be utilized to evaluate blood glucose levels and glycemic control at the dental office. Early screening and diagnosis of diabetes intervenes in the long-term complications of both the diseases and helps in better disease management. The objective of this review was to highlight the reliability and acceptability of different techniques using gingival crevicular blood for evaluation of blood glucose levels along with their advantages and limitations. By this literature review, we analysed over 60 studies published regarding the use of gingival crevicular blood for screening diabetes in periodontitis patients. The data was gathered via Google scholar and Medline using the keywords “Periodontitis, Inflammation, Glycemic control, Diabetes, Gingival crevicular blood” from the years 1993-2019. Keywords: Periodontitis; Inflammation; Glycemic Control; Diabetes; Gingival Crevicular Blood


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