scholarly journals Antimicrobial Characterization of Erythorbyl Laurate for Practical Applications in Food and Cosmetics

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Jin-Woo Kim ◽  
Hyunjong Yu ◽  
Kyung-Min Park ◽  
Pahn-Shick Chang
Keyword(s):  
Antibacterial Activity ◽  
Skin Diseases ◽  
Gram Positive ◽  
Multifunctional Additive ◽  
Water Emulsion ◽  
Practical Applications ◽  
Gram Positive Bacteria ◽  
Food Borne ◽  
Bacteria And Fungi ◽  
Oil In Water Emulsion

In this study, antimicrobial spectrum of erythorbyl laurate (EL) against bacteria and fungi, leading to food-borne and infectious skin diseases, was evaluated for its practical applications in food and cosmetics. Furthermore, the influences of environmental factors including pH, oxidative stress, and dispersion medium on antimicrobial activity of EL were investigated. The three Gram-positive bacteria and the three molds were susceptible to 3.0 mM EL, while the yeast was susceptible to 6.0 mM EL. It was demonstrated EL retained antibacterial activity against Staphylococcus aureus after being oxidized while the antibacterial activity against the three Gram-positive bacteria including S. aureus, Bacillus cereus, and Listeria monocytogenes was significantly enhanced as decrease of pH from 7.0 to 5.0. Moreover, EL exhibited bactericidal effects against both Gram-positive and Gram-negative bacteria in an oil-in-water emulsion. Treatment of 5.0 mM EL for 4 h reduced 5.29 ± 0.24, 6.01 ± 0.18, 5.95 ± 0.13, and 6.24 ± 0.30 log CFU/mL against S. aureus, L. monocytogenes, Pseudomonas aeruginosa, and Escherichia coli, respectively. In a multipassage resistance selection study, it was observed minimum inhibitory concentrations of EL against S. aureus were not increased over 20 passages, indicating EL might not develop drug resistance of bacteria. This study suggests EL has a potential to be applied as the multifunctional additive in food and cosmetics.

Antibacterial activity of magnesium oxide nanoparticles prepared by Calcination method

2019 ◽  
Vol 10 (03) ◽  
Author(s):  
Elaf Ayad Kadhem ◽  
Miaad Hamzah Zghair ◽  
Sarah , Hussam H. Tizkam, Shoeb Alahmad Salih Mahdi ◽  
Hussam H. Tizkam ◽  
Shoeb Alahmad
Keyword(s):  
Antibacterial Activity ◽  
Magnesium Oxide ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Magnesium Oxide Nanoparticles ◽  
Agar Disc

magnesium oxide nanoparticles (MgO NPs) were prepared by simple wet chemical method using different calcination temperatures. The prepared NPs were characterized by Electrostatic Discharge (ESD), Scanning Electron Microscope (SEM) and X-ray Diffraction (XRD). It demonstrates sharp intensive peak with the increase of crystallinty and increase of the size with varying morphologies with respect to increase of calcination temperature. Antibacterial studies were done on gram negative bacteria (E.coli) and gram positive bacteria (S.aureus) by agar disc diffusion method. The zones of inhibitions were found larger for gram positive bacteria than gram negative bacteria, this mean, antibacterial MgO NPs activity more active on gram positive bacteria than gram negative bacteria because of the structural differences. It was found that antibacterial activity of MgO NPs was found it has directly proportional with their concentration.

scholarly journals A novel bis(pyrazolyl)methane compound as a potential agent against Gram-positive bacteria

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pedro Seguí ◽  
John J. Aguilera-Correa ◽  
Elena Domínguez-Jurado ◽  
Christian M. Sánchez-López ◽  
Ramón Pérez-Tanoira ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Inhibitory Effect ◽  
Eukaryotic Cell ◽  
Liver Carcinoma ◽  
Gram Positive ◽  
Minimal Inhibitory Concentrations ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
Therapeutic Compounds ◽  
Toxic Concentrations

AbstractThis study was designed to propose alternative therapeutic compounds to fight against bacterial pathogens. Thus, a library of nitrogen-based compounds bis(triazolyl)methane (1T–7T) and bis(pyrazolyl)methane (1P–11P) was synthesised following previously reported methodologies and their antibacterial activity was tested using the collection strains of Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. Moreover, the novel compound 2P was fully characterized by IR, UV–Vis and NMR spectroscopy. To evaluate antibacterial activity, minimal inhibitory concentrations (MICs), minimal bactericidal concentrations (MBCs), minimum biofilm inhibitory concentrations (MBICs), and minimum biofilm eradication concentrations (MBECs) assays were carried out at different concentrations (2–2000 µg/mL). The MTT assay and Resazurin viability assays were performed in both human liver carcinoma HepG2 and human colorectal adenocarcinoma Caco-2 cell lines at 48 h. Of all the synthesised compounds, 2P had an inhibitory effect on Gram-positive strains, especially against S. aureus. The MIC and MBC of 2P were 62.5 and 2000 µg/mL against S. aureus, and 250 and 2000 µg/mL against E. faecalis, respectively. However, these values were > 2000 µg/mL against E. coli and P. aeruginosa. In addition, the MBICs and MBECs of 2P against S. aureus were 125 and > 2000 µg/mL, respectively, whereas these values were > 2000 µg/mL against E. faecalis, E. coli, and P. aeruginosa. On the other hand, concentrations up to 250 µg/mL of 2P were non-toxic doses for eukaryotic cell cultures. Thus, according to the obtained results, the 2P nitrogen-based compound showed a promising anti-Gram-positive effect (especially against S. aureus) both on planktonic state and biofilm, at non-toxic concentrations.

Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane

2021 ◽  
pp. 088532822110044
Author(s):  
Haiyang Wang ◽  
Toshinari Maeda ◽  
Toshiki Miyazaki
Keyword(s):  
Antibacterial Activity ◽  
Methyl Methacrylate ◽  
Bone Cement ◽  
Setting Time ◽  
Antibacterial Properties ◽  
The Body ◽  
Apatite Formation ◽  
Gram Positive ◽  
E Coli ◽  
Gram Positive Bacteria

Bone cement based on poly(methyl methacrylate) (PMMA) powder and methyl methacrylate (MMA) liquid is a very popular biomaterial used for the fixation of artificial joints. However, there is a risk of this cement loosening from bone because of a lack of bone-bonding bioactivity. Apatite formation in the body environment is a prerequisite for cement bioactivity. Additionally, suppression of infection during implantation is required for bone cements to be successfully introduced into the human body. In this study, we modified PMMA cement with γ-methacryloxypropyltrimetoxysilane and calcium acetate to introduce bioactive properties and 2-( tert-butylamino)ethyl methacrylate (TBAEMA) to provide antibacterial properties. The long-term antibacterial activity is attributed to the copolymerization of TBAEMA and MMA. As the TBAEMA content increased, the setting time increased and the compressive strength decreased. After soaking in simulated body fluid, an apatite layer was detected within 7 days, irrespective of the TBAEMA content. The cement showed better antibacterial activity against Gram-negative E. Coli than Gram-positive bacteria; however, of the Gram-positive bacteria investigated, B. subtilis was more susceptible than S. aureus.

Antimicrobial Activity of Isopteropodine

2005 ◽  
Vol 60 (5-6) ◽  
pp. 385-388 ◽  
Author(s):  
Rubén García ◽  
Cesia Cayunao ◽  
Ronny Bocic ◽  
Nadine Backhouse ◽  
Carla Delporte ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Gram Positive ◽  
Uncaria Tomentosa ◽  
Gram Positive Bacteria

Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.

Identification of novel aminopiperidine derivatives for antibacterial activity against Gram-positive bacteria

2016 ◽  
Vol 26 (13) ◽  
pp. 3148-3152 ◽  
Author(s):  
Hee-Yeol Lee ◽  
Kyung-Mi An ◽  
Juyoung Jung ◽  
Je-Min Koo ◽  
Jeong-Geun Kim ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Gram Positive ◽  
Gram Positive Bacteria

Colonisation of finfish substrate inhabited by black soldier fly larvae by blow flies, bacteria, and fungi

2020 ◽  
Vol 6 (3) ◽  
pp. 291-304 ◽  
Author(s):  
E. Bernard ◽  
J. Villazana ◽  
A. Alyokhin ◽  
J. Rose
Keyword(s):  
Microbial Communities ◽  
Additional Treatment ◽  
Blow Fly ◽  
Gram Positive ◽  
Black Soldier Fly ◽  
Gram Positive Bacteria ◽  
Fungal Abundance ◽  
Black Soldier Fly Larvae ◽  
Fly Larvae ◽  
Bacteria And Fungi

Black soldier fly, Hermetia illucens (L.) (Diptera: Stratiomyidae) can be used for recycling a wide variety of organic wastes. However, these wastes are also suitable for colonisation by pest fly species, including the blow fly Lucilia sericata (Meigen) (Diptera: Calliphoridae), and by pathogenic microorganisms. We tested effects of the presence of black soldier fly larvae (BSFL) on recruitment and retention of blow fly larvae, as well as on composition and dynamics of microbial communities in finfish-based substrates. Substrates inhabited by BSFL contained approximately one-tenth of the L. sericata pupae found in the control substrate even when BSFL were removed prior to the introduction of gravid L. sericata females. Furthermore, almost three-quarters of L. sericata released into substrates previously colonised by BSFL emigrated within 24 h, while no such emigration was detected for the control substrates. Unlike previous studies, bacterial community was heavily dominated by Gram-positive species. Overall bacterial abundance on BSFL substrates declined approximately two-fold compared to the control substrate, while fungal abundance increased. However, surviving microbial communities were still robust and diverse, and continued to be dominated by Gram-positive bacteria. On the other hand, Gram-negative Shigella sonnei, which is a common cause of diarrhoea in humans, was more than 200 times less abundant in BSFL substrates compared to the control throughout the experiment. Repellent and antibiotic properties observed in this study are advantageous for using BSFL in remediation of finfish wastes. However, additional treatment of remaining residue may still be necessary to eliminate all biological contamination.

scholarly journals Antibacterial activity of Baccharis trimera (Less.) DC. (carqueja) against bacteria of medical interest

Revista CERES ◽  
2013 ◽  
Vol 60 (5) ◽  
pp. 731-734 ◽  
Author(s):  
Álan Alex Aleixo ◽  
Karina Marjorie Silva Herrera ◽  
Rosy Iara Maciel de Azambuja Ribeiro ◽  
Luciana Alves Rodrigues dos Santos Lima ◽  
Jaqueline Maria Siqueira Ferreira
Keyword(s):  
Antibacterial Activity ◽  
Folk Medicine ◽  
Salmonella Typhi ◽  
Bacterial Strains ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Clinical Interest ◽  
Antibacterial Susceptibility ◽  
Baccharis Trimera ◽  
Medical Interest

Baccharis trimera (Less.) (Asteraceae), popularly know as "carqueja", is a species commonly used in folk medicine for the treatment or prevention of diseases. In this context, the purpose of this work was to study the antibacterial activity of crude hydroalcoholic extract from Baccharis trimera against Gram-positive bacterial strains (Staphylococcus aureus ATCC 29213, Staphylococcus saprophyticus ATCC 15305, Staphylococcus epidermidis ATCC 12228, Enterococcus faecalis ATCC 19433) and Gram-negative bacteria (Escherichia coli EHEC ATCC 43895, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 27736, Salmonella typhi ATCC 19430) of clinical interest. Antibacterial susceptibility was evaluated by broth microdilution assay following the CLSI (formerly the NCCLS) guidelines. The extract from B. trimera showed antibacterial activity against Gram-positive bacteria and the most interesting result was obtained against S. epidermidis that presented Minimal Inhibitory Concentration of 250μg/mL. These results indicate that B. trimera have bacterisostatic potential against Gram-positive bacterial strains of medical interest and could serve as a base for further studies on the use of isolated compounds from this species as future antimicrobials.

Corrigendum to “The immune response after stimulation with wall components of gram-positive bacteria and fungi” [Immunol. Lett. 159 (1–2) (2014) 23–29]

2014 ◽  
Vol 161 (1) ◽  
pp. 165
Author(s):  
Evdoxia Tsigou ◽  
Stavros Aloizos ◽  
Pavlos Myrianthefs ◽  
Stavros Gourgiotis ◽  
Athanassios Tsakris ◽  
...  
Keyword(s):  
Immune Response ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Bacteria And Fungi ◽  
Wall Components

scholarly journals Novel Polymer Material for Efficiently Removing Methylene Blue, Cu(II) and Emulsified Oil Droplets from Water Simultaneously

Polymers ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1393 ◽  
Author(s):  
Jie Cao ◽  
Jianbei Zhang ◽  
Yuejun Zhu ◽  
Shanshan Wang ◽  
Xiujun Wang ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Separation Efficiency ◽  
Crosslinking Agent ◽  
Cost Effective ◽  
Preparation Process ◽  
Water Emulsion ◽  
Practical Applications ◽  
Oil In Water ◽  
Oil In Water Emulsion ◽  
Oil Fouling

The pollution of water resources has become a worldwide concern. The primary pollutants including insoluble oil, toxic dyes, and heavy metal ions. Herein, we report a polymer adsorbent, named SPCT, to remove the above three contaminants from water simultaneously. The preparation process of SPCT contains two steps. Firstly, a hydrogel composed of sulfonated phenolic resin (SMP) and polyethyleneimine (PEI) was synthesized using glutaraldehyde (GA) as the crosslinking agent, and the product was named SPG. Then SPCT was prepared by the reaction between SPG and citric acid (CA) at 170 ∘ C. SPCT exhibited an excellent performance for the removal of methylene blue (MB) and Cu(II) from aqueous solution. For a solution with a pollutant concentration of 50 mg L−1, a removal efficiency of above 90% could be obtained with a SPCT dosage of 0.2 g L−1 for MB, or a SPCT dosage of 0.5 g L−1 for Cu(II), respectively. SPCT also presented an interesting wettability. In air, it was both superhydrophilic and superoleophilic, and it was superoleophobic underwater. Therefore, SPCT could successfully separate oil-in-water emulsion with high separation efficiency and resistance to oil fouling. Additionally, SPCT was easily regenerated by using dilute HCl solution as an eluent. The outstanding performance of SPCT and the efficient, cost-effective preparation process highlight its potential for practical applications.

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