scholarly journals Deep Learning-Based Analysis of the Effect of Cardiac Color Ultrasound on Chronic Obstructive Pulmonary Disease under Mask Region

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Yusheng He ◽  
Fei Chen ◽  
Qingyun Chen
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Deep Learning ◽  
Lung Function ◽  
Right Ventricular ◽  
Lung Disease ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Right ◽  
Experimental Group

This study was developed to analyze the application effect of cardiac ultrasound (CUS) in chronic obstructive pulmonary disease (COPD) patients. A mask region-based convolutional neural network (Mask R-CNN) algorithm was constructed for lung disease detection based on deep learning algorithms, and it was compared with the RetinaNet algorithm for lung disease detection. The results showed that the sensitivity, specificity, accuracy, and running time of the Mask R-CNN algorithm were statistically greater than those of the RetinaNet algorithm ( P < 0.05 ). A total of 92 cases confirmed with lung diseases by pathology were set as experimental group, including 23 cases of COPD classification for level I, II, III, and IV. In addition, 20 cases of healthy adults were selected as control group. The experimental group was compared with the control group, as the lung function decreased, the right atrium diameter (RAD), right ventricle diameter (RVD), and the right ventricular anterior wall thickness (RVAW) increased, the right ventricular ejection fraction (RVEF) gradually decreased, and the AWT-RV, the interventricular septal thickness (IVST), and right ventricular end-diastole volume (RVEDV) changed greatly in the lung function classification ( P < 0.01 ). It was concluded that the CUS based on the Mask R-CNN algorithm could show the changes in bronchial lumen volume at all levels and could detect and evaluate the lung function diseases.

scholarly journals Determination of the most informative indicators of right-ventricular dysfunction in patients with chronic obstructive pulmonary disease

2020 ◽  
Vol 15 (2) ◽  
pp. 115-123
Author(s):  
Mikhail Kharitonov ◽  
◽  
Victor Tarasov ◽  
Sergei Grishaev ◽  
Alexander Filippov ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Right Ventricle ◽  
Right Ventricular ◽  
Ventricular Dysfunction ◽  
Right Ventricular Dysfunction ◽  
Control Group ◽  
Chronic Obstructive ◽  
Study Group ◽  
Obstructive Pulmonary Disease ◽  
The Right

The aim of the article was the evaluation of structural and functional indicators that reflect the nature of right heart remodeling in patients with chronic obstructive pulmonary disease (COPD) in order to identify the most informative indicators of right ventricular heart dysfunction. The study included 60 patients, who were on inpatient treatment. Patients were divided into two groups: I — study group with COPD (n = 30), and II control group — patients of comparable age without COPD (n = 30). During hospitalization, all patients underwent ECHO-KG with an emphasis on evaluating the systolic-diastolic parameters of the right ventricle. Criteria for inclusion in the study: age over 50 years, presence of COPD, signed informed consent when reading the terms of the study. Exclusion criteria: history/course of neoplastic or hematological disease, systemic connective tissue diseases, documented ischemic disease, valvular heart disease, interstitial lung disease, bronchial asthma. When comparing echocardiographic indicators of right ventricular (RV) function detected significant decrease of systolic function the RV — TAPSE (16.64 ± 4.0 vs 23.21 ± 2.31; p = 0.043), S’(12.57 ± 1.87 vs. 14.96 ± 1.09; p = 0.026), estimated RV EF (49.27 ± 9.23 vs 66.12 ± 7.42; p = 0.021), EFSRV (55.58 ± 7.16 vs 72.4 ± 13.06; p = 0.01) and higher rates SDLA (49.55 ± 6.0 vs 27.1 ± 5.29; p = 0.023) in the study group 1. Measure of right ventricular arterial pairing TAPSE/SDLA was significantly reduced compared with the control group (0.36 ± 0.05 vs 0.86 ± 0.14; p = 0.01). In the main 1 group of patients with COPD, there was a tendency increase of the myocardial performance index (TEI index) (0.76 ± 0.42 vs 0.59 ± 0.22; p = 0.43), which is probably associated with a violation of the relaxation of the right ventricle. To confirm the presence of diastolic RV dysfunction in patients with COPD (in comparison with the control group) revealed significant changes in the indicators obtained from transtricuspid flow — E/Atk (0.67 ± 0.02 vs 1.5 ± 0.38; p = 0.016). The dynamics of the degree of severity of right ventricular dysfunction, estimated using the proposed indicators, may be another additional characteristic of the success of therapy to achieve disease control in patients with COPD.

CONDITION OF HEMODYNAMICS IN THE PULMONARY CIRCULATION OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) CONCURRENT WITH METABOLIC SYNDROME WITH HYPERTROPHY AND ATROPHY OF THE MYOCARDIUM

2019 ◽  
Vol 72 (8) ◽  
pp. 1491-1493
Author(s):  
Viktor P. Boriak ◽  
Svitlana V. Shut’ ◽  
Tetiana A. Trybrat ◽  
Olena V. Filatova
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Metabolic Syndrome ◽  
Right Ventricular ◽  
Pulmonary Disease ◽  
Pulmonary Circulation ◽  
Contractile Function ◽  
Ventricular Myocardium ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Right

Introduction: In recent years, COPD is observed as not an isolated, but an associated pathology, in particular, concurrent with metabolic syndrome. The aim of the research is to identify the differences in changes of the rheopulmonography parameters (RPG) depending on the presence of hypertrophy or atrophy of the right ventricular myocardium in patients with COPD concurrent with metabolic syndrome.. Materials and methods: We studied changes in rheopulmonography (RPG) in 145 patients with chronic obstructive pulmonary disease (COPD) concurrent with metabolic syndrome. Results: We detected precapillary hypertension of the pulmonary circulation in patients with right ventricular myocardial hypertrophy: anacrotism serration; flattened peak of the systolic wave; decreased Vcp; high placement of incisura; horizontal course of catacrotism; decreased amplitude of the systolic wave (in this case, due to a greater increase in the resistance of the blood flow in the pulmonary vessels than the decreased impact volume of the right ventricle); prolonged Q-a (in this group of patients, it depends more on hypertension of the pulmonary circulation than on the reduction of contractile function of the myocardium). In atrophy of the right ventricular myocardium, the following changes in the RPG were revealed: decreased systolic wave at its dramatic rise; prolonged Q-a (in this case, due to the weakened heart contraction); Vmax reduction (it reflects the reduction of myocardial contractility); in hypertrophy of the myocardium, Vcp., unlike RPG, does not decrease, which is explained by the decrease in the pressure of the pulmonary circulation. Conclusions: We believe that these changes in RPG allow differentiating hypertrophy and right ventricular myocardial atrophy along with established diagnostic criteria, and can be used as markers for the diagnosis and treatment of COPD concurrent with metabolic syndrome.

scholarly journals Evaluation of outcomes of medication therapy management (MTM) services for patients with chronic obstructive pulmonary disease (COPD)

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Mingyue Liu ◽  
Jiayun Liu ◽  
Zhihui Geng ◽  
Shuang Bai
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Medication Therapy Management ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Therapy Management ◽  
Medication Therapy ◽  
Copd Patients ◽  
Experimental Group

Objectives: To evaluate the outcomes of clinical pharmacist-led medication therapy management (MTM) services for patients with chronic obstructive pulmonary disease (COPD). Methods: Two hundred COPD patients admitted by the Department of Respiratory and Critical Care Medicine of Baoding No.1 Central Hospital during January 2019 and December 2020 were randomly assigned to a control group (n =100) and an experimental group (n =100). Patients in the control group received conventional treatment, while those in the experimental group were provided with MTM services based on the conventional treatment for comparative analysis of outcome measures, including use of antibacterials during hospital stay, length of stay (LoS), costs of hospitalization (CoH), cases of adverse drug reactions (ADRs), and medication adherence (MA) and COPD assessment test (CAT) score one and six months after discharge. Results: Compared with the control group, the experimental group had reduced use of antibacterials during hospital stay, LoS, CoH, and ADR rate (P <0.05). After discharge, patients in both groups showed remarkable improvements in MA and CAT scores in comparison with their performances upon admission, and the experimental group exhibited better MA and higher CAT score than the control group, with the differences indicating statistical significance (P <0.05). Conclusion: MTM designed for COPD patients can improve pharmacist-led service quality and clinical outcomes of COPD. doi: https://doi.org/10.12669/pjms.37.7.4518 How to cite this:Liu M, Liu J, Geng Z, Bai S. Evaluation of outcomes of medication therapy management (MTM) services for patients with chronic obstructive pulmonary disease (COPD). Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4518 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Virtual Reality Technology Combined with Comprehensive Pulmonary Rehabilitation on Patients with Stable Chronic Obstructive Pulmonary Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Xiangmei Xie ◽  
Jie Fan ◽  
Huihong Chen ◽  
Ling Zhu ◽  
Ting Wan ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Virtual Reality ◽  
Pulmonary Disease ◽  
Technical Support ◽  
Control Group ◽  
Chronic Obstructive ◽  
Virtual Reality Technology ◽  
Obstructive Pulmonary Disease ◽  
Breathing Exercises ◽  
Experimental Group

With the popularization of medical knowledge and the development of medical technology, people pay more and more attention to COPD. This paper mainly studies the effect of virtual reality technology combined with comprehensive lung rehabilitation on patients with stable chronic obstructive pulmonary disease. 60 patients with stable chronic obstructive pulmonary disease were selected to collect their general information, such as name, gender, and age. They were divided into the experimental group and control group, 30 patients in each group. The experimental group was treated with virtual reality technology combined with lung rehabilitation, while the control group was treated with conventional rehabilitation. Patients in both groups needed medication and participated in a 30-minute disease description activity once a week. In addition, patients in the control group should walk for 20 minutes every day to monitor muscle fatigue. Breathing exercises are also carried out regularly. Patients are instructed to use their lips and abdomen for 5 minutes each time. The respiratory rate was 7 beats per minute. In addition to the routine training of the control group, the experimental group will also train the simulated bicycle for 20 minutes, which will be automatically saved on the computer after the training. After the experiment, the muscle function and motor ability of the two groups were evaluated, and the results were statistically analyzed. The total self-efficacy scores of patients before and after telemedicine technical support increased significantly (2.15 ± 0.21 before telemedicine technical support, 2.39 ± 0.20 after telemedicine technical support), and the difference was statistically significant ( P < 0.05 ). The results show that the application of virtual reality technology can improve the rehabilitation belief of patients and strengthen the training effect.

scholarly journals WeChat as a Platform for Baduanjin Intervention in Patients With Stable Chronic Obstructive Pulmonary Disease in China: Retrospective Randomized Controlled Trial (Preprint)

2020 ◽  
Author(s):  
Junjie Bi ◽  
Wei Yang ◽  
Ping Hao ◽  
Yongmei Zhao ◽  
Dan Wei ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Lung Function ◽  
Pulmonary Rehabilitation ◽  
Life Quality ◽  
Satisfaction Survey ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Significant Difference ◽  
Before And After

BACKGROUND Pulmonary rehabilitation is a crucial part of the nonpharmacological treatment of stable chronic obstructive pulmonary disease (COPD), but management remains problematic. WeChat could serve as a useful tool in patient management. Baduanjin is a popular exercise in China that is usually applied in pulmonary rehabilitation, which has been confirmed to be effective in improving lung function and life quality. OBJECTIVE This study aimed to explore the efficiency of WeChat in the management of Baduanjin exercise in COPD patients. METHODS A total of 200 patients from the respiratory department of Putuo Hospital participated in the Baduanjin rehabilitation project from September 2018 to October 2019, and were randomly assigned to the WeChat and control groups and followed up using the WeChat platform or telephone for 12 weeks. The frequency of Baduanjin exercise, lung function (percentage of forced expiratory volume in 1 second predicted, FEV1% predicted), and COPD assessment test (CAT) scores were collected and compared between the two groups. The number of message exchanges and a satisfaction survey on the WeChat platform were used to assess the feasibility of WeChat management outside the hospital. RESULTS The Baduanjin exercise frequency significantly differed between the control group and WeChat group (<i>F</i>=33.82, <i>P&lt;</i>.001) and across various time points (<i>F</i>=214.87, <i>P&lt;</i>.001). After the follow-up on WeChat, there were fewer patients not performing Baduanjin exercise. The FEV1% predicted value significantly differed before and after Baduanjin exercise in the control group (<i>Z</i>=−3.686, <i>P</i>&lt;.001) and the WeChat group (<i>Z</i>=−6.985, <i>P&lt;</i>.001). A significant difference in the FEV1% predicted value was observed after Baduanjin exercise between the two groups (<i>Z</i>=−3.679, <i>P</i>&lt;.001). The CAT score significantly differed before and after Baduanjin exercise in the control group (<i>Z</i>=−4.937, <i>P&lt;</i>.001) and the WeChat group (<i>Z</i>=−5.246, <i>P</i>&lt;.001). A significant difference in the CAT score was observed after Baduanjin exercise between the two groups (<i>Z</i>=−5.246, <i>P&lt;</i>.001). The number of completed Baduanjin exercises, lung function, and CAT scores in active patients were higher than those in nonactive patients. All satisfaction survey items were scored with more than 4 points. Among the items, the highest score (mean 4.54, SD 0.77) was for continued WeChat management, followed by the effective management of Baduanjin exercise (mean 4.46, SD 0.87). The patients in the WeChat group showed much higher enthusiasm for and compliance with Baduanjin exercise, resulting in better life quality and lung function. The patients were very satisfied with the WeChat management because of the obvious curative effect and home feeling. CONCLUSIONS The WeChat platform provided a feasible, effective, and sustainable management plan for Baduanjin rehabilitation. CLINICALTRIAL Chinese Clinical Trial Registry ChiCTR1900028248; http://www.chictr.org.cn/showprojen.aspx?proj=46995

scholarly journals Clinical efficacy of acupoint application of Chinese herbal medicine to prevent acute exacerbation of stable chronic obstructive pulmonary disease: A study protocol for a randomized placebo-controlled trial

2019 ◽  
Author(s):  
Zhang Chuantao ◽  
Yang Hongjing ◽  
Gan Wenfan ◽  
Xie Xiaohong ◽  
Gao Peiyang ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Clinical Trial ◽  
Acute Exacerbation ◽  
Controlled Trial ◽  
Control Group ◽  
Chronic Obstructive ◽  
Efficacy And Safety ◽  
Obstructive Pulmonary Disease ◽  
Chinese Herbal ◽  
Experimental Group

Abstract Background: Chronic obstructive pulmonary disease (COPD) is a major public health problem that severely affects the quality of life of patients and may even endanger their lives. The key to prevent the progression of COPD is active treatment during the stable phase that prevents and reduces acute exacerbation of COPD. Although modern medicine has achieved significant results in relieving the clinical manifestations of COPD, it is difficult to prevent its progression and acute exacerbation entirely. As one of the classic aspects of acupuncture and moxibustion therapy, acupoint application of Chinese herbal medicine (CHM) can improve the clinical efficacy of Western medicine in treating COPD. To date, however,there is no high-quality clinical trial to assess the effectiveness of CHM acupoint application directly in preventing acute exacerbation of stable COPD.Thus, we designed this randomized placebo-controlled clinical trial to evaluate the long-term efficacy and safety of CHM acupoint application in preventing the acute exacerbation of stable COPD.Methods: The study is a randomized, double-blind, placebo-controlled trial, in which 200 stable COPD patients will be randomly and equally divided into the experimental group or control group. Both groups will undergo standard Western medicine treatment; however, the patients in the experimental group will be also treated with CHM acupoint application, while the control group will be given placebo acupoint application. The duration of the treatment will be 1 month and a follow-up for 11 months. The primary outcome will be the number of acute exacerbation episodes of COPD, and the secondary outcomes will include the lung function, St George's Respiratory Questionnaire, COPD Assessment Test, and 6-Minute Walk Test. A safety assessment will also be performed during the trial.Discussion: The aim of this study is to evaluate the efficacy and safety of CHM acupoint application in preventing acute exacerbation of stable COPD. Our study will provide sound evidence to support the evidence-based medicine of CHM acupoint application as an additional measure in the prevention of acute exacerbation of stable COPD.

scholarly journals Regression analysis to estimate the response of the respiratory organs to exposure of air microtoxicants in chronic obstructive pulmonary disease

2021 ◽  
pp. 45-52
Author(s):  
T. I. Vitkina ◽  
L. V. Veremchuk ◽  
T. A. Gvozdenko ◽  
E. E. Mineeva
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Respiratory Failure ◽  
Lung Function ◽  
Respiratory System ◽  
Toxic Metals ◽  
Regression Models ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The City

Inroduction. The assessment of the respiratory system is of particular importance in the context of increasing impact of anthropogenic factors on human health. Aim. Evaluation the response of the lung function indices to the effects of micro-suspensions and toxic metals in patients with chronic obstructive pulmonary disease (COPD), using regression models. Materials and methods. The study involved 60 patients with stable mild-to-moderate COPD and 30 healthy people (the control group). The analysis of lung function was carried out by spirometry and body plethysmography. Arterial oxygen saturation (SaO2 ) was measured by pulse oximetry. Exhaled CO2 concentration and blood carboxyhemoglobin (COHb%) concentration were assessed using a portable analyzer MicroCO Meter. The pollution of the city atmosphere was assessed by aerosol suspensions of solid particles in the areas of residence of the examined patients. Fractional composition of suspended particles (0-1, 1-10, 10-50, 50-100, 100-400, 400-700,> 700 μm; %) were analyzed in the areas of residence of the examined patients. Toxic metal (Pb, Cr, Mn, Fe, Co, Ni, Cu, Zn; μg/L) levels in the air samples were determined. The statistical module "Multiple regression" was used for assessing the response of functional parameters of the respiratory system. Results. The analysis of one-factor and multi-factor regression models made it possible to identify both trigger factors of dust and technogenic air pollution and the synergistic effect of the influence of dominant factors. It has been shown that multifactorial reactions to technogenic impact manifest as altered blood oxygen saturation and carboxyhemoglobin level and thereby contribute to the development of respiratory failure. Conclusion. Patients with COPD exhibited increased bronchial resistance to the effect of the trigger factor (Pb – 1 hazard class) associated with high motorization of the city. The response of pulmonary gas exchange (SaO2 ) to Pb in the control group indicates prolonged exposure to toxic metals can cause developing respiratory failure even in the healthy population of the city.

Application of Dejian Psychosomatic Therapy to Smokers with Stable Chronic Obstructive Pulmonary Disease

2021 ◽  
Vol 7 (6) ◽  
pp. 5103-5107
Author(s):  
Liu Xin
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Treatment Group ◽  
Lung Function ◽  
Pulmonary Disease ◽  
Statistical Significance ◽  
Good Effect ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Group Control Group

To explore the intervention effect of Dejian psychosomatic therapy on chronic obstructive pulmonary disease (COPD) in elderly smokers, in as to improve clinical impact of COPD in smokers who are the aged. Forty elderly smokers with COPD were comprise of treatment group, control group, which are trained for 45 days to test the following indicators. Vital mass Index (VMI), forced Vital capacity (FVC), Maximum Chase air volume (MVV) and so on showed significant improvement in lung function indicators in both the treatment group and the control group (P < 0.05). Improvement impact of control group was not better than that of the treatment group, with statistical significance (P < 0.01). Dejian psychosomatic therapy has a systematic good effect on copd smokers, promoting the improvement and promotion of lung function, and strengthening the physical function of copd smokers in stable stage.

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