scholarly journals Data Mining-Based Stability and Prescription Analysis of Neonatal Parenteral Nutrition Solution

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Huiqin Li ◽  
Wenyan Fan ◽  
Xiaoyan Han ◽  
Hao Yang

In order to evaluate the stability of neonatal parenteral nutrition solution, in this paper, the prescription of neonatal parenteral nutrition solution was investigated and analyzed. The formula of neonatal parenteral nutrition solution used, particularly the one utilized in this study, is commonly used in clinical practice. All the neonatal parenteral nutrition solution required for the test was prepared on the purification workbench in a sterile environment. The time points of stability of parenteral nutrient solution were 0, 12, and 24 hours, respectively, and three parallel samples were taken at each time point. Likewise, to investigate the stability of two kinds of fat milk injection in parenteral nutrition solution of neonates and provide a reference for subsequent experiments and to investigate the influence of electrolyte, amino acid, temperature, pH value, mixing sequence, and the final concentration of glucose on the stability of neonatal parenteral nutrition solution, the stability indexes of neonatal parenteral nutrition liquid mainly include appearance, pH, insoluble particles, fat milk particle size, and particle size distribution. Neonatal parenteral nutrition solution prescriptions from the First Affiliated Hospital of Jinan University, specifically from January to June 2019, were collected and statistically processed. The experimental data were processed by SPSS 19.0 software and data mining technology. The results were expressed as mean ± standard deviation and statistically processed by ANOVA. P < 0.05 was considered statistically significant. The results showed that the stability of neonatal parenteral nutrient solution was influenced by many factors. The formula of neonatal parenteral nutrition solution is generally reasonable, but there are unreasonable phenomena which are needed to be improved further if feasible.

2018 ◽  
Vol 789 ◽  
pp. 26-30
Author(s):  
Dan Shi Zhu ◽  
Li Wei Wei ◽  
Xiao Jun Ren ◽  
Xue Hui Cao ◽  
He Liu ◽  
...  

Acidity is an important influence factor for juice stability. In this study, the effects of acidityon stability of cloudy apple juice were investigated. The stability indexes, such as, turbidity, cloudvalue, cloud stability, and particle size distribution (PSD) were measured at pH 2.0, 2.5, 3.0 and 3.5,along with the untreated juice (pH 3.8) as control group. The results showed that, pH has significanteffects on turbidity, chrome (C*), cloud value, and D50, D90 in PSD of cloudy apple juice. The juicehad a better stabilization at pH 2.5. At this pH condition, the turbidity, cloud value, cloud stability ofjuice was the best. In addition, at pH 2.5, the color of the juice was better, the particles were smaller,and the particle sizes were more uniform. By this study, a theoretical reference could be provided forimproving stability of cloudy apple juice and extending juice shelf life.


2019 ◽  
Vol 948 ◽  
pp. 140-145
Author(s):  
Al Dina N. Khoerunisa ◽  
Prihati Sih Nugraheni ◽  
Mohammad Fahrurrozi ◽  
Wiratni Budhijanto

The aqueous dispersion of nanochitosan was prepared by polyelectrolyte complex (PEC) method with various mixing ratios of chitosan and polyanions, i.e., chitosan-glucomannan, chitosan-hyaluronic acid, and chitosan-Arabic gum. The formation of nanochitosan was carried out by adding the polyanion solution dropwise into the acid solution of chitosan. The study aimed to determine the best polyanion among the variations tested in this study, concerning the targeted particle size and the stability of the dispersion over time. Particle size distribution was observed by Particle Size Analyzer (PSA). The result indicated that Arabic gum gave the smallest average particle size, i.e. 192.5 nm, at a chitosan/polyanion mass ratio of 3:1 and pH value of 4.


2013 ◽  
Vol 68 (2) ◽  
pp. 276-282 ◽  
Author(s):  
X. N. Yang ◽  
F. Y. Cui

Nano-sized titanium dioxide in the aquatic environment has a potential impact on the environment and human health. In this study, the impact of pH value, dissolved organic matter (DOM) and divalent cations (Ca2+) on the stability of titanium dioxide nanoparticles (nano-TiO2) in an aqueous environment was investigated in batch tests. The results showed that the particle size of nano-TiO2 was not sensitive to pH value but was inversely proportional to zeta potential. The nano-TiO2 becomes more stable with surface zeta potential, accompanied by small particle size and high dispersion. In the presence of DOM, the particle size was smaller and the stability of nano-TiO2 could be enhanced. This might be a synergistic effect of the ligand exchange and electrostatic force. Particle size increased with the addition of Ca2+ and the stability decreased.


2011 ◽  
Vol 374-377 ◽  
pp. 869-874 ◽  
Author(s):  
Xiao Nan Yang ◽  
Fu Yi Cui ◽  
Xiao Ying Mu ◽  
Zhi Wei Zhao

Nano-sized titanium dioxide in aquatic environment poses potential impact on environment and human health. In this research, the impact of pH value, humic acid (HA) and divalent cations (Ca2+) on the stability of titanium dioxide nanoparticles(NPs) in the aqueous enviorment was investigated using a batch test. The results showed that the particle size of TiO2 NPs was not sensitive to the pH value but presented inversely proportional to zeta potential. The TiO2 NPs become more stable along with surface zeta potential, accompany with small particle size and high dispersion. In the presence of HA, the particle size was smaller and TiO2 NPs could be stabilized. This might be synergistic effect of the ligand exchange and electrostatic force. Meanwhile, NPs particle size increased with the addition of Ca2+ and the stability of TiO2 NPs became decreased.


2011 ◽  
Vol 55-57 ◽  
pp. 1886-1891
Author(s):  
Xian Mei Zhu ◽  
Gang Hu Cheng ◽  
Hong Zhao Liu

The control of particle size and its distribution has become more and more important both in theory and in practice of emulsion polymerization field. In this study, cationic styrene-acrylate copolymer containing functional monomer was converted into water-soluble polymers by reaction with quaternising agents and acids with the free-soap emulsion polymerization method. The latex was obtained at the existence of nitrogen by the copolymerization of hydrophobic monomer styrene and 2-ethylhexyl acrylate, hydrophilic monomer dimethylaminoethyl methacrylate, modified PVA-0588 as the emulsifiers. The influences of the amount of azoisobutyronitrile initiator, the amount of dimethyl sulphate quaternising agent, reactivity ratio between monomers, charge density and pH value on the preparation process were discussed. The particle size and particle distribution was strongly affected by these factors. The results showed that the latex with narrow particle distribution and mean particle size about 100nm was obtained under redox system by adjusting 33% monomer to become precursor and dropping the rest of 67% monomer, after polymerization, N,N-dimethylamino groups were fully quaternised with dimethyl sulphate to improve the stability of the solutions. The glass temperature of polymer was 58.1°C, as pH values range of solution was 3~5, the stability and charge density of polymer emulsion could improve.


2012 ◽  
Vol 512-515 ◽  
pp. 779-784 ◽  
Author(s):  
Yang Hou ◽  
Ping Hu ◽  
Wen Bo Han

The dispersion of SiC nanopowders in ethanol solution was studied by sedimentation test, particle size measurement and TEM analysis. The dispersion behavior of SiC nanopowders in ethanol solution was strongly dependent on the pH values, types and amounts of dispersant. PEI was found to be effective for the dispersion of SiC nanopowders in ethanol solution. With the addition of PEI, the isoelectric points of SiC nanopowders in ethanol solution were at pH 9.5, and shift to pH 12.3. The stability of SiC suspension increased with the dispersant content increasing until reached 2.5 wt% PEI. The suitable pH value for the dispersion of SiC nanopowders should lower than 10.


Energies ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 398 ◽  
Author(s):  
Renate Zapf-Gottwick ◽  
Matthias Zorn ◽  
Jessica Nover ◽  
Michael Koch ◽  
Carolin Feifel ◽  
...  

Due to the toxicity of cadmium (Cd) and the scarcity of telluride (Te), CdTe-based photovoltaic modules have been under discussion during the last few years. In particular, the stability of CdTe in aqueous solutions is under debate. Here we show that the stability of CdTe depends not only on the pH of water-based solutions but also on size and surface treatment of CdTe particles. We compare milled module pieces with CdTe powders of different particle size. The leaching of CdTe is conditioned by the outdiffusion of Cd and Te at the interface between CdTe particles and the aqueous solution. The smaller the particle size, the faster the leaching. Therefore, milled module pieces decompose faster than CdTe powders with relatively large grains. We observe a dependence on time t according to t0.43. The room temperature diffusion coefficients are calculated as DCd ≈ 3 × 10−17 cm2/s for Cd, and DTe ≈ 1.5 × 10−17 cm2/s for Te in pH4. The chemical instability in aqueous solutions follows thermodynamic considerations. The solution behavior of Cd and Te depends on the pH value and the redox potential of the aqueous solutions. Chemical treatments such as those used in solar cell production modify the surface of the CdTe particles and their leaching behavior.


1975 ◽  
Vol 34 (02) ◽  
pp. 426-444 ◽  
Author(s):  
J Kahan ◽  
I Nohén

SummaryIn 4 collaborative trials, involving a varying number of hospital laboratories in the Stockholm area, the coagulation activity of different test materials was estimated with the one-stage prothrombin tests routinely used in the laboratories, viz. Normotest, Simplastin-A and Thrombotest. The test materials included different batches of a lyophilized reference plasma, deep-frozen specimens of diluted and undiluted normal plasmas, and fresh and deep-frozen specimens from patients on long-term oral anticoagulant therapy.Although a close relationship was found between different methods, Simplastin-A gave consistently lower values than Normotest, the difference being proportional to the estimated activity. The discrepancy was of about the same magnitude on all the test materials, and was probably due to a divergence between the manufacturers’ procedures used to set “normal percentage activity”, as well as to a varying ratio of measured activity to plasma concentration. The extent of discrepancy may vary with the batch-to-batch variation of thromboplastin reagents.The close agreement between results obtained on different test materials suggests that the investigated reference plasma could be used to calibrate the examined thromboplastin reagents, and to compare the degree of hypocoagulability estimated by the examined PIVKA-insensitive thromboplastin reagents.The assigned coagulation activity of different batches of the reference plasma agreed closely with experimentally obtained values. The stability of supplied batches was satisfactory as judged from the reproducibility of repeated measurements. The variability of test procedures was approximately the same on different test materials.


2012 ◽  
Vol 8 (1) ◽  
pp. 123-132 ◽  
Author(s):  
Zsuzsanna Horváth ◽  
Béla Marosvölgyi ◽  
Christine Idler ◽  
Ralf Pecenka ◽  
Hannes Lenz

Abstract - There are several problems in storing wood chips freshly harvested from short rotation plantations, which result in quality losses as well as in dry matter and energy losses. The factors influencing the degradation of raw material are examined in this paper with special focus on fungal development. An excessive growth of fungi is connected to dry matter losses and also to an increased health risk during raw material handling. The following factors were measured during 6 months storage of poplar wood chips depending on particle size: box temperature, moisture content, pH-value, appearance of fungi in the storage and the concentration of fungal particles in the air. The results show a close connection between particle size, temperature and attack of fungi. During the storage mesophilic and termophilic species of the genera Alternaria, Aspergillus, Cladosporium, Mucor and Penicillium appeared. The concentration of fungal particles is the highest for fine chips and decreases in bigger particles. There was a special focus on the investigation of the properties of coarse chips (G 50), which represent a good compromise between handling, storage losses and health risk due to fungal development.


2019 ◽  
Author(s):  
Jose Julio Gutierrez Moreno ◽  
Marco Fronzi ◽  
Pierre Lovera ◽  
alan O'Riordan ◽  
Mike J Ford ◽  
...  

<p></p><p>Interfacial metal-oxide systems with ultrathin oxide layers are of high interest for their use in catalysis. In this study, we present a density functional theory (DFT) investigation of the structure of ultrathin rutile layers (one and two TiO<sub>2</sub> layers) supported on TiN and the stability of water on these interfacial structures. The rutile layers are stabilized on the TiN surface through the formation of interfacial Ti–O bonds. Charge transfer from the TiN substrate leads to the formation of reduced Ti<sup>3+</sup> cations in TiO<sub>2.</sub> The structure of the one-layer oxide slab is strongly distorted at the interface, while the thicker TiO<sub>2</sub> layer preserves the rutile structure. The energy cost for the formation of a single O vacancy in the one-layer oxide slab is only 0.5 eV with respect to the ideal interface. For the two-layer oxide slab, the introduction of several vacancies in an already non-stoichiometric system becomes progressively more favourable, which indicates the stability of the highly non-stoichiometric interfaces. Isolated water molecules dissociate when adsorbed at the TiO<sub>2</sub> layers. At higher coverages the preference is for molecular water adsorption. Our ab initio thermodynamics calculations show the fully water covered stoichiometric models as the most stable structure at typical ambient conditions. Interfacial models with multiple vacancies are most stable at low (reducing) oxygen chemical potential values. A water monolayer adsorbs dissociatively on the highly distorted 2-layer TiO<sub>1.75</sub>-TiN interface, where the Ti<sup>3+</sup> states lying above the top of the valence band contribute to a significant reduction of the energy gap compared to the stoichiometric TiO<sub>2</sub>-TiN model. Our results provide a guide for the design of novel interfacial systems containing ultrathin TiO<sub>2</sub> with potential application as photocatalytic water splitting devices.</p><p></p>


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