scholarly journals The Clinical Value of 3D Ultrasonic Measurement of the Ratio of Gestational Sac Volume to Embryo Volume in IoT-Based Prediction of Pregnancy Outcome

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yong Wang ◽  
Tiantian Li ◽  
Lichun Zhang ◽  
Jing Li ◽  
Bo Zou ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcome ◽  
Spontaneous Abortion ◽  
Gestational Age ◽  
Transvaginal Ultrasound ◽  
Yolk Sac ◽  
Ultrasonic Measurement ◽  
Normal Delivery ◽  
Significant Difference ◽  
Gestational Sac

The objective of the research study is to investigate the use of three-dimensional ultrasonic measurement technology, to determine the size of gestational sac and embryo volume, and to use the ratio of gestational sac volume to embryo volume in IoT-based prediction of pregnancy outcome. The abnormal and normal pregnancy identifiers are there, which assists in prediction of pregnancy outcomes: whether the pregnancy is normal or may suffer pregnancy loss during first trimester. For the observational study, 500 singleton pregnant women who made an appointment for delivery in Qiqihar Hospital from January 2015 to June 2019 were considered. The 500 pregnant women received transvaginal ultrasound at 6+0 ∼ 8+0 weeks of gestational age to measure gestational sac volume (GSV), yolk sac volume (YSV), and germ volume (GV). According to pregnancy outcome, they were divided into fine group (n = 435) and abortion group (n = 65). Among the 500 cases, 435 had normal delivery and 65 had abortions. According to the results of gestational age (GA) analysis, the pregnancy success rates at 6 (n = 268), 7 (n = 184), and 8 weeks (n = 48) were 85.8%, 87.5%, and 91.7%, respectively. Comparison of pregnancy failure rate among the three groups shows statistically significant difference. The morphology of germ, yolk sac, and gestational sac cannot be used as a predictor of pregnancy outcome in various degrees. The results of multivariate Cox proportional regression analysis show the following: the ratio of germ volume (GV) to gestational sac volume (GSV) ( P = 0.008 ) has an impact on the prediction of spontaneous abortion prognosis, showing statistically significant difference; yolk sac volume (YSV), germ volume (GV), and gestational sac volume (GSV) have no effect on the prediction of spontaneous abortion prognosis ( P > 0.05 ). The ratio of GSV to germ volume has a strong prognostic value for pregnancy results. To a certain extent, the ratio of gestational sac volume to germ volume can predict spontaneous pregnancy abortion at 6th week of gestation, providing a theoretical basis for clinical ultrasound pregnancy examination indicators.

Antithyroid Antibodies in Sera of Women with Spontaneous Abortion and Normal Pregnancies

2020 ◽  
Vol 70 (12) ◽  
pp. 4326-4331
Keyword(s):  
Autoimmune Disease ◽  
Pregnant Women ◽  
Pregnancy Outcome ◽  
Spontaneous Abortion ◽  
Autoimmune Thyroiditis ◽  
Normal Pregnancy ◽  
Thyroid Antibodies ◽  
Outcome Group ◽  
Significant Difference ◽  
Group A

Autoimmune thyroiditis is the most frequent autoimmune disease. We analyzed the association between the presence and value of titer of anti-thyroid antibodies (atbs) and spontaneous abortion (SA). Moreover, we analyzed the association between TSH values and the presence of anti-thyroids atbs. We tested anti-TPO and anti-TG atbs in 257 women: 85 probands, 87 pregnant women with normal pregnancy outcome, and 85 with SA. We tested TSH in 87 pregnant women with normal pregnancy outcome. No significant difference was found between the prevalence of cases with positive anti-TPO and anti-TG atbs in women with normal pregnancy outcome vs. SA patients. In women with positive atbs titer, anti-TPO and anti-TG values were higher in SA group compared with normal pregnancy outcome group. A significant threshold was reached only for anti-TG atbs. TSH values were higher in pregnant women with positive anti-TPO and anti-TG values compared with those with a negative atbs titer. In pregnant women with positive anti-thyroid atbs titers, spontaneous abortion group patients have higher anti-TG titers than women with normal pregnancy outcome. TSH values are higher in the group of patients with positive anti-TPO and anti-TG atbs titers compared with the group of patients with negative anti-TPO and anti-TG values. Keywords: Anti-TPO, anti-TG, pregnancy outcome, spontaneous abortion, TSH

scholarly journals Assessment of Length of Maternal Cervix between 18 and 24 weeks of Gestation in a Low-Risk Brazilian Population

2017 ◽  
Vol 39 (12) ◽  
pp. 647-652
Author(s):  
Soraya Andrade ◽  
Fernando Andrade ◽  
Edward Araujo Júnior ◽  
Cláudio Pires ◽  
Rosiane Mattar ◽  
...  
Keyword(s):  
Linear Regression ◽  
Pregnant Women ◽  
Gestational Age ◽  
Polynomial Regression ◽  
Transvaginal Ultrasound ◽  
Cervical Length ◽  
Low Risk ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Ideal

Purpose To determine cervical biometry in pregnant women between 18 and 24 weeks of gestation and the ideal mode of measurement of cervical length in cases of curved and straight cervical morphology. Methods The uterine cervices of 752 low-risk pregnant women were assessed using transvaginal ultrasound in a prospective cross-sectional study. In women with straight uterine cervices, cervical biometry was performed in a continuous manner. In women with curved uterine cervices, the biometry was performed using both the continuous and segmented techniques (in segments joining the cervical os). Polynomial regression models were created to assess the correlation between the cervical length and gestational age. The paired Student t-test was used to compare measuring techniques. Results The cervical biometry results did not vary significantly with the gestational age and were best represented by linear regression (R2 = 0.0075 with the continuous technique, and R2 = 0.0017 with the segmented technique). Up to the 21st week of gestation, there was a predominance of curved uterine cervix morphology (58.9%), whereas the straight morphology predominated after this gestational age (54.2%). There was a significant difference between the continuous and the segmented measuring methods in all the assessed gestational ages (p < 0.001). Conclusion Cervical biometry in pregnant women between 18 and 24 weeks was represented by a linear regression, independently of the measuring mode. The ideal measuring technique was the transvaginal ultrasound performed at a gestational age ≥21 weeks.

The effect of ear acupressure medicine at the “Shen Men” point on the nausea and vomiting during pregnancy

2021 ◽  
Vol 15 (5) ◽  
pp. 1774-1779
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadije Rezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Intervention Group ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Health Clinics ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Mean ◽  
The Difference

Introduction & Objective: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Therefore, the aim of this study was to investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retching during pregnancy. Materials and Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics of Zabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group were trained to apply pressure on their ears’ Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords: Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis

The comparison of USG measured cervical length in pregnant women with previous induced abortion versus those who have not had an induced abortion

2019 ◽  
Vol 8 (10) ◽  
pp. 4024
Author(s):  
Harshita Naidu ◽  
Nivedita Hegde ◽  
Anjali M. ◽  
Rohini Kanniga ◽  
Akhila Vasudeva
Keyword(s):  
Pregnant Women ◽  
Preterm Delivery ◽  
Transvaginal Ultrasound ◽  
Induced Abortion ◽  
Cervical Length ◽  
Care Hospital ◽  
Spontaneous Preterm Delivery ◽  
Increased Risk ◽  
Significant Difference ◽  
History Of

Background: The majority of women who undergo induced abortion are young and of low parity. Hence, it is desirable to look for any association effects of induced abortion with future reproductive outcomes. In this study, we aim to compare ultrasound measured cervical length in pregnant women with previous induced abortion versus those who have not had an induced abortion.Methods: This was a prospective observational study performed at tertiary care hospital. Total of 400 patients were recruited, divided into two groups. Patients with an induced abortion in previous pregnancy were included as cases and those with no history were taken as controls. Cervical length was measured by transvaginal ultrasound in all participants at 11-14, 18-22 and 28-32 weeks. Pregnancies were followed up to note incidence of spontaneous preterm delivery, preterm pre labour rupture of membranes (PPROM), threatened preterm, and second trimester miscarriage.Results: Authors have found that there was no significant difference in the cervical length of pregnant patients with or without a history of prior induced abortions.  In our study authors found that mean cervical length at 11-14weeks, 18-22 weeks, and 28-32 weeks was 3.47±0.126cm and 3.48±0.195cm; 3.44±0.296cm and 3.49±0.182cm; 3.36±0.477cm and 3.42±0.310cm respectively among cases and controls. However, there was a demonstrably increased risk of spontaneous preterm delivery, PPROM and threatened preterm in patients with a history of prior induced abortion.Conclusions: Authors conclude that previous induced abortion increases the risk of threatened preterm, PPROM, spontaneous preterm delivery in the subsequent pregnancy. But, this risk is not predictable by measuring cervical length as the mean cervical length remained the same in both the groups.

scholarly journals A Comparative Study of Relationship between Micronutrients and Gestational Diabetes

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Farideh Akhlaghi ◽  
Seyyed Majid Bagheri ◽  
Omid Rajabi
Keyword(s):  
Gestational Diabetes ◽  
Pregnant Women ◽  
Gestational Age ◽  
Control Group ◽  
Study Group ◽  
Inclusion Criteria ◽  
Control Groups ◽  
Significant Difference ◽  
Micronutrient Concentration ◽  
And Control

In this paper, we studied the relation between the micronutrient and gestational diabetes. Therefore, we measured micronutrient concentration including Ni, Al, Cr, Mg, Fe, Zn, Cu, and Se in serum of women with gestational diabetes between 24 and 28 weeks of gestational age (study group) who had inclusion criteria and comparison with micronutrient levels in normal pregnant women with same gestational age (control group). Results showed that there was no significant difference between the serum micronutrient level (Ni, Al, Cr, Mg, Zn, Cu, Se) in study and control groups except serum level of iron which in serum of gestational diabetic women was lower than normal pregnant women and difference was significant.

scholarly journals Chemotherapy for breast cancer during pregnancy induces vascular alterations and impaired development of placental villi: a preliminary histopathological study.

2019 ◽  
Author(s):  
Alessandro Del Gobbo ◽  
Giovanna Scarfone ◽  
Fedro Alessandro Peccatori ◽  
Antonella Villa ◽  
Wally Ossola ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Birth Weight ◽  
Pregnant Women ◽  
Gestational Age ◽  
First Trimester ◽  
Histopathological Study ◽  
Third Trimester ◽  
Significant Difference ◽  
Placental Villi ◽  
Fetal Malformations

Abstract Breast cancer is diagnosed in approximately 1/3000 pregnant women. Chemotherapy may be administered after the first trimester, with improved maternal outcome and relatively few pregnancy and offspring complications. Nonetheless, no information about the effects of different chemotherapy regimens on placenta architecture and vasculature are available. Methods To evaluate histological alterations in placentas of women affected by breast cancer and treated with chemotherapy during pregnancy, we retrospectively analyzed 23 placentas of patients affected by breast cancer and treated with chemotherapy during pregnancy and 23 control placentas of women without breast cancer and with physiological pregnancies of the same gestational age. Results All the patients had breast ductal infiltrating carcinoma, 19 of 23 cases had a G3 cancer. All patients were treated with 2-6 cycles of chemotherapy starting after 16 weeks of gestation, with different protocols. No hypertensive complications and no pre-eclampsia episodes were observed; birth weight was consistent with gestational age in all babies in both group with no uneventful outcomes and no perinatal mortality or fetal malformations. Twenty out of 23 cases (86%) showed hypoxia-induced villous alterations, including increased syncytial knotting (Tenney-Parker changes), perivillar fibrin deposits, distal villous hypoplasia or accelerated maturation and focal villous chorangiosis. These alterations were found in 19 out of 23 controls (83%), with no statistically significant difference between the two groups. Conclusions These results shows that chemotherapy in the second and third trimester of pregnancy may lead to non-specific alterations in placental vasculature and morphology.

scholarly journals Predictive Value of Maternal Anemia in Cases of Fetal Growth Restriction

2021 ◽  
Vol 5 (06) ◽  
pp. 01-06
Author(s):  
Waleed M. Tawfik ◽  
Shaimaa R. Abdelmaksoud ◽  
Ghada M. Mahmoud
Keyword(s):  
Pregnant Women ◽  
Fetal Growth ◽  
Gestational Age ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Deficiency Anemia ◽  
Haematocrit Level ◽  
Maternal Anemia ◽  
Anemic Patient ◽  
Significant Difference

Anemia can be defined as a state of inadequate O2 delivery to tissues due to reduction of the O2 carrying capacity of blood practically, anemia is diagnosed when there is reduction in the hemoglobin concentration or haematocrit level below normal values. Iron deficiency anemia is a major public health problem among women of reproductive age in most of developing countries approximately 50% of pregnant women and 35% of non pregnant women are anemic. These nutritional disorders, has profound negative effects on pregnancy outcome, health of mothers and babies. The objective of this study: Is to evaluate the maternal anemia during pregnancy as a risk factor for fetal growth restriction. The study was done this study conducted on 120 pregnant women. Pregnant women with inclusion criteria: Singleton pregnancy, Gestational age more than 28 week and Hb level less than 10mg/dl. We exclude multiple pregnancy, Gestational age less than 28 week, Hb level more than 10 mg/dl and other medical disorder with pregnancy. The results of this study reveal the following: There was significant difference between group 1, 2, 3, 4 as regard to Hb level, (PCV), (MCV), (MCH), (MCHC), (Ht) and (CBC). The restriction of fatal growth was significant lower in sever anemic patient rather than mild or moderate anemic patient In conclusions: The result of this study shows that there was restriction of fatal growth was significantly high in sever anemic group than mild or moderate group also, incidence of low birth weight and risk of fatal morbidity or mortality was significantly high in sever anemic group than mild or moderate group.

The correlation between vitamin D and maternal/infant outcomes, inflammatory response in pregnant women

2020 ◽  
Author(s):  
Yarong Wei ◽  
Xinye Jiang ◽  
Ting Qiu ◽  
Jinyan Fu ◽  
Heng Zhang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Preterm Birth ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Spontaneous Abortion ◽  
Gestational Age ◽  
Serum Vitamin ◽  
Multivariate Logistic Regression Analysis ◽  
Premature Delivery ◽  
Vitamin D Levels

Abstract Purposes To analyze the effects of vitamin D deficiency in pregnant women on common adverse pregnancy outcomes and small for gestational age (SGA) and to detect the expression of inflammatory factors in pregnant women to provide a theoretical basis for the treatment of vitamin D deficiency in pregnant women. Methods Serum samples from pregnant women from January 2015 to December 2015 were collected to measure the 25-(OH)D level. The effects of maternal age, pregnancy, season, parity and temperature on vitamin D levels in pregnant women were recorded. Then, the relationship between vitamin D levels and gestational diabetes mellitus, gestational hypertension, premature rupture of membranes, cesarean section, premature delivery and spontaneous abortion, and neonatal gestational age were analyzed. The expression of IL-6 and TNF-α in serum was detected by RT-PCR and western blot. Results The incidence of vitamin D deficiency, insufficiency and sufficiency in pregnant women in this region was 83.28%, 15.36% and 1.36%, respectively. Age, pregnancy, sampling season and parity were the influencing factors on vitamin D level, and multivariate logistic regression analysis showed that summer, autumn and temperature were protective factors for adequate vitamin D in pregnant women (P <0.05). Vitamin D levels in pregnant women were associated with preterm birth, spontaneous abortion and SGA. The incidences of preterm birth, spontaneous abortion and SGA were higher in the vitamin D deficiency group (P<0.05). ConclusionThe serum vitamin D level of pregnant women in this area is low and is affected by multiple factors such as age, pregnancy, season, parity and temperature. Low vitamin D levels can increase the risk of premature birth, spontaneous abortion and SGA in pregnant women, and its low expression is common. As it also leads to inflammation, increasing the level of vitamin D in the serum of pregnant women can effectively reduce the occurrence of related diseases.

Prevalence of Lower Back Pain in Pregnant Women with Pre-Eclampsia

2021 ◽  
Vol 15 (9) ◽  
pp. 2773-2776
Author(s):  
Parveen Shafi ◽  
Rahim Khan ◽  
Tariq Ahmad ◽  
Syed Alam Zeb ◽  
Ahsan Sajjad
Keyword(s):  
Back Pain ◽  
Pregnant Women ◽  
Lower Back Pain ◽  
Gestational Age ◽  
Domestic Work ◽  
Cross Sectional ◽  
Lower Back ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Objective: The aim of this study is to determine the prevalence of lower back pain in pregnant women with pre-eclampsia. Study Design: Cross sectional study Place and Duration: Mardan Medical Complex/BKMC, Tahseel Headquarter Hospital, Takht Bhai Mardan, Swabi Medical Complex /GKMC, from October 2019 to October 2021. Methods: Total 160 pregnant women were presented in this study. Patients were aged between 18-45 years. Detailed demographics of enrolled cases age, body mass index, gestational age, and residency and education status were calculated after taking informed written consent. Patients were divided into two groups. Group I had 80 patients with pre-eclampsia and group II had 80 patients with normotensive. Gravidity among both groups was assessed. Symptoms and prevalence of lower back pain among both groups were assessed and compared. Complete data was analyzed by SPSS 22.0 version. Results: Mean age of the patients in group I was 27.09±5.66 years with mean gestational age 33.14±7.41 weeks while in group II mean age was 26.55±8.26 years with mean gestational age 32.47±8.33 weeks. Thirty seven patients (46.3%) in group I was primigravida and 40 (50%) in group II was primigravida. Thirty nine patients (48.8%) had urban residency in group I and in group II thirty seven (46.3%) cases were from urban area. Frequency of literacy among both groups were 42 (52.5%) and 44 (55%). Prevalence of lower back pain in group I was 55 (68.8%) higher as compared to group II 53 (66.3%) with no any significant difference. Domestic work was the most common cause among both groups followed by social work (Job), lifting of heavy object and medication pain. Conclusion: We concluded in this study the prevalence of lower back pain among pregnant women was significantly high among both pre-eclampsia and normotensive cases. Most common causes of lower back among women was domestic work. Health professionals must be proactive in diagnosing LBP and providing proper management due to the enormous impact of it on the quality of life. Keywords: Pregnant Women, Low Back Pain, Prevalence, Symptoms, causes.

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