Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications

The Withania genus comes from the Solanaceae family and includes around 23 species, spread over some areas of the Mediterranean, Asia, and East Africa. Widely used in traditional medicine for thousands of years, these plants are rich in secondary metabolites, with special emphasis on steroidal lactones, named withanolides which are used as ingredients in numerous formulations for a plethora of diseases, such as asthma, diabetes, arthritis, impotence, amnesia, hypertension, anxiety, stress, cancer, neurodegenerative, and cardiovascular diseases, and many others. Among them, Withania somnifera (L.) Dunal is the most widely addressed species from a pharmacological and agroindustrial point of view. In this sense, this review provides an overview of the folk uses, phytochemical composition, and biological activity, such as antioxidant, antimicrobial, anti-inflammatory, and cytotoxic activity of W. somnifera, although more recently other species have also been increasingly investigated. In addition, their health-promoting effects, i.e., antistress, anxiolytic, adaptogenic, antirheumatoid arthritis, chemoprotective, and cardiorespiratory-enhancing abilities, along with safety and adverse effects are also discussed.

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The Chemical Composition and Nutritional Value of Chia Seeds—Current State of Knowledge

Nutrients ◽

10.3390/nu11061242 ◽

2019 ◽

Vol 11 (6) ◽

pp. 1242 ◽

Cited By ~ 18

Author(s):

Bartosz Kulczyński ◽

Joanna Kobus-Cisowska ◽

Maciej Taczanowski ◽

Dominik Kmiecik ◽

Anna Gramza-Michałowska

Keyword(s):

Chemical Composition ◽

Food Industry ◽

Nutritional Value ◽

Nutritive Value ◽

Blood Lipid ◽

Herbaceous Plant ◽

Blood Lipid Profile ◽

Current State ◽

Health Promoting ◽

Potential Use

Chia (Salvia hispanica) is an annual herbaceous plant, the seeds of which were consumed already thousands of years ago. Current research results indicate a high nutritive value for chia seeds and confirm their extensive health-promoting properties. Research indicates that components of chia seeds are ascribed a beneficial effect on the improvement of the blood lipid profile, through their hypotensive, hypoglycaemic, antimicrobial and immunostimulatory effects. This article provides a review of the most important information concerning the potential application of chia seeds in food production. The chemical composition of chia seeds is presented and the effect of their consumption on human health is discussed. Technological properties of chia seeds are shown and current legal regulations concerning their potential use in the food industry are presented.

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Withania Somnifera Linn as Herbal Source of Diverse Pharmacological Potential - A Comprehensive Review

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v12i3.4788 ◽

2021 ◽

Vol 12 (3) ◽

pp. 1879-1885

Author(s):

Kajal Panchal ◽

Praveen K Dixit ◽

Rajni Saini KM ◽

Nagarajan K ◽

Puspendra Kumar ◽

...

Keyword(s):

Cardiovascular Diseases ◽

Blood Count ◽

Withania Somnifera ◽

Chemical Constituents ◽

Review Article ◽

Health Food ◽

Pharmacological Activities ◽

Comprehensive Review ◽

Pharmacological Potential ◽

Solanaceae Family

Ashwagandha, also known as Indian winter cherry, belonging to the Withania Somnifera Linn. (Solanaceae) family, (commonly available as Churna). Africa, the Mediterranean, and India are all home to this species. It is 30-50cm high and mainly found in the drier parts of India. Since it raises haemoglobin (red blood count) and hair melanin. Withania Somnifera is known as "Rasayana," which means "strong rejuvenator" in Ayurvedic jargon. In ethnomedicine, it is a well-known health food and herbal tonic that is used to treat cardiovascular diseases. It can be used as a single herb or as part of polyherbal or herbo-mineral formulations for humans. It is traditionally used to treat various diseases such as inflammation, asthma, dyspepsia, hypertension, rheumatism, tumor, anxiety, hemopoietic, antimicrobial, depression, immunomodulation, antiulcer, hepatoprotective activities, Alzheimer’s, Parkinson’s disease, rejuvenating properties and syphilis. It has wide variety of chemical constituents such as withanoloides, flavonoid, saponins, glycosides, alkaloids, tannins, steroids have been studied. Despite the fact that previous review articles on this plant have been written, this review article is provided to bring together all of the most recent knowledge on its phytochemical and pharmacological activities.

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Cnidoscolus aconitifolius: Nutritional, phytochemical composition and health benefits – A review

Bioactive Compounds in Health and Disease ◽

10.31989/bchd.v4i11.865 ◽

2021 ◽

Vol 4 (11) ◽

pp. 260

Author(s):

Anil Panghal ◽

Anjali Onakkaramadom Shaji ◽

Kiran Nain ◽

Mukesh Kumar Garg ◽

Navnidhi Chhikara

Keyword(s):

Biological Activity ◽

Folk Medicine ◽

Food Product ◽

South American ◽

Green Leafy Vegetable ◽

Phytochemical Composition ◽

Functional Attributes ◽

Cnidoscolus Aconitifolius ◽

Pharmacological Studies ◽

Health Promoting

Cnidoscolus aconitifolius belonging to Euphorbiaceae family is widely used as a folk medicine among South American countries such as Mexico and Brazil. C. aconitifolius can be considered as a potential green leafy vegetable, largely due to the presence of various secondary metabolites. The different bioactive compounds such as phenolic acids, Alkaloids, saponins, flavonoids etc. along with terpenoids with unique structure are exclusive for this genus. C. aconitifolius has numerous nutraceutical benefits proven with pharmacological studies such as anti-diabetic, hepatoprotective, anti-microbial etc. The recent upsurge of consumer interest for health promoting products has opened up new vistas for C. aconitifolius application in food product research and development. Limited knowledge about this underutilized plant is representing an opportunity to explore the plant as novel ingredient with vast functional attributes. Keywords: Cnidoscolus aconitifolius, phytochemicals, nutraceutical potential, biological activity, diabetes

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STUDY OF CORIANDER SEED OIL (Coriandrum sativum L.)

Science and Technology Development Journal ◽

10.32508/stdj.v13i3.2151 ◽

2010 ◽

Vol 13 (3) ◽

pp. 29-38

Author(s):

Ha Bich Phan ◽

Thach Ngoc Le

Keyword(s):

Biological Activity ◽

Chemical Composition ◽

Essential Oil ◽

Seed Oil ◽

Coriandrum Sativum ◽

Conventional Heating ◽

Geranyl Acetate ◽

Physical And Chemical ◽

Coriander Seed Oil ◽

Coriander Seed

Coriandrum sativum L. belongs to the Apiaceae family, which is cultivated in Dong Nai province, in this paper its seed oil of was studied. The essential oil was extracted by hydrodistillation. We used two methods for activating of hydrodistillation: conventional heating and microwave irradiating. Its physical and chemical indexes were measured. The chemical composition of this oil was identified by GC/MS and quantified by GC/FID. Linalool (75.51-77.21 %), and geranyl acetate (15.64-12.79 %) were the main constituents of the oil which were obtained in 0,32-0.39 % yield. The biological activity of this oil was reported.

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PEAS AND PRODUCTS OF ITS PROCESSING OF - NONCONVENTIONAL RAW MATERIAL RESOURCES

STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS. In the frame of the XXIII Agribusiness Forum of the South of Russia and the Exhibition «Interagromash» Volume 1 ◽

10.23947/interagro.2020.1.407-409 ◽

2020 ◽

Author(s):

D.Y. Bolgova ◽

◽

N.A. Tarasenko ◽

Z.S. Mukhametova ◽

◽

...

Keyword(s):

Chemical Composition ◽

Human Health ◽

Food Production ◽

Food Industry ◽

Raw Material ◽

Plant Proteins ◽

Material Resources ◽

The Rich

Nutrition is an important factor that affects human health. The use of plant proteins as various additives in food production has now been actively developed. The rich chemical composition of pea grains determines the possibility of application in the food industry. Peas are characterized by good assimilability and degree of digestion.

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Prebiotic Carbohydrates for Therapeutics.

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1871530320666200929140522 ◽

2020 ◽

Vol 20 ◽

Author(s):

Renuka Basavaiah ◽

Prapulla Siddalingaiya Gurudutt

Keyword(s):

Immune Response ◽

Lipid Metabolism ◽

Bacterial Infection ◽

Food Industry ◽

Health Benefits ◽

Well Being ◽

Intestinal Disease ◽

Mineral Absorption ◽

Health Promoting ◽

Insulin Dependent

: The food industry is constantly shifting focus based on prebiotics as health-promoting substrates rather than just food supplements. A prebiotic is ‘‘a selectively fermented ingredient that allows specific changes, both in the composition and/or activity in the gastrointestinal microflora that confers benefits upon host well-being and health.” Prebiotics exert a plethora of health-promoting effects, which has lead to the establishment of multimillion food and pharma industries. The following are the health benefits attributed to prebiotics: mineral absorption, better immune response, increased resistance to bacterial infection, improved lipid metabolism, possible protection against cancer, relief from poor digestion of lactose, and reduction in the risk of diseases such as intestinal disease, non-insulin dependent diabetes, obesity and allergy. Numerous studies in both animals and humans have demonstrated the health benefits of prebiotics.

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Chemical Composition and Biological Activity of the Essential Oil and Solvent Extracts of

The Open Bioactive Compounds Journal ◽

10.2174/1874847301004010043 ◽

2017 ◽

Vol 04 (1) ◽

pp. 43-49

Author(s):

Amir Reza Jassbi ◽

Mehdi Zare ◽

Fatemeh Heidary Jamebozorgi

Keyword(s):

Biological Activity ◽

Chemical Composition ◽

Essential Oil

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The Distribution of Minerals in Crucial Plant Parts of Various Elderberry (Sambucus spp.) Interspecific Hybrids

Plants ◽

10.3390/plants10040653 ◽

2021 ◽

Vol 10 (4) ◽

pp. 653

Author(s):

Nataša Imenšek ◽

Vilma Sem ◽

Mitja Kolar ◽

Anton Ivančič ◽

Janja Kristl

Keyword(s):

Chemical Composition ◽

Mineral Composition ◽

Plant Development ◽

Interspecific Hybrids ◽

Food Industry ◽

Mineral Content ◽

Genetic Breeding ◽

Plant Parts ◽

Early Stages ◽

Superior Genotypes

In view of growing requirements of the food industry regarding elderberries (genus Sambucus), a need to increase their productivity and improve their chemical composition has emerged. With this purpose in mind, numerous elderberry interspecific hybrids have been created. In the present work, the content of minerals in their crucial plant parts was studied. It was also investigated whether superior genotypes regarding the mineral composition of berries and inflorescences could be predicted at early stages of plant development. The results showed that elderberry leaves contained the highest amounts of Ca, Mg, Mn, Zn, and Sr, while K and P were predominant in fruit stalks. Fe and Al prevailed in roots and Cu in bark. Although berries showed lower mineral content compared to other plant parts, their mineral content is not negligible and could be comparable to other commonly consumed berries. Genotypes with a favorable mineral content of inflorescences and berries could be predicted on the basis of known mineral composition of their shoots and leaves. The study also indicates that S. nigra genotypes and the majority of interspecific hybrids analyzed are suitable for further genetic breeding or cultivation.

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Potential application of gold nanoparticles in food packaging: a mini review

Gold Bulletin ◽

10.1007/s13404-021-00290-9 ◽

2021 ◽

Author(s):

Saeed Paidari ◽

Salam Adnan Ibrahim

Keyword(s):

Gold Nanoparticles ◽

Potential Application ◽

Food Industry ◽

Food Packaging ◽

Industrial Applications ◽

Mechanisms Of Action ◽

Microbial Load ◽

Food Sector ◽

The Past ◽

Industry Applications

AbstractIn the past few decades, there have been remarkable advances in our knowledge of gold nanoparticles (AuNPs) and synthesizing methods. AuNPs have become increasingly important in biomedical and industrial applications. As a newly implemented method, AuNPs are being used in nanopackaging industries for their therapeutic and antibacterial characteristics as well as their inert and nontoxic nature. As with other NPs, AuNPs have privileges and disadvantages when utilized in the food sector, yet a significant body of research has shown that, due to the specific nontoxic characteristics, AuNPs could be used to address other NP flaws. In this mini review, we present synthesizing methods, food industry applications, and mechanisms of action of gold nanoparticles. Regarding the investigations, gold nanoparticles can play a major role to reduce microbial load in foodstuff and therefore can be implemented in food packaging as an effective approach.

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