Redefining the Phenotype of Dental Caries

Dental caries is a multifactorial infectious disease and a major public health problem estimated to affect 60-90% of school children as well as a vast number of adults. The aim of this work was to define patterns of progression of the disease based on longitudinal data in contrast to using a cross-sectional assessment. dmft/DMFT scores were collected at ages 5, 12, 14, 16, 17, and 18 from 876 individuals. We tested our newly defined phenotypes for association with genetic variants in genes shown to be associated with caries. We generated genotyping data using Taqman chemistry in markers of genes involved in processes such as enamel formation and salivary contributions. Kallikrein 4 (KLK4) was found to show a significant association with the created phenotypes (p = 0.0008 in a recessive model for low caries experience in the primary dentition vs. high caries experience in the primary dentition, and p = 0.0004 in a recessive model for caries free primary dentition vs. high caries experience in the primary dentition).

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Dental Caries Experience among Industrial Workers in Parwanoo, Himachal Pradesh, India

International Healthcare Research Journal ◽

10.26440/ihrj/0304.07255 ◽

2019 ◽

Vol 3 (4) ◽

pp. 150-153

Author(s):

Kesari Singh ◽

Abhinav Bhasker

Keyword(s):

Dental Caries ◽

Dental Health ◽

Public Health Problem ◽

Cross Sectional Study ◽

Himachal Pradesh ◽

Oral Disease ◽

Caries Experience ◽

Major Public Health Problem ◽

Industrial Workers ◽

Cross Sectional

Background: Dental caries, the oral disease with multifactorial causes is a major public health problem leading go medically significant morbidity and impacting the general health of a population directly or indirectly. Dental caries is known to affect people from every population. Objective: To assess dental caries experience in permanent dentition among industrial workers in Parwanoo, Himachal Pradesh, India. Materials and Methods: This cross-sectional study was conducted among 1024 industrial workers of Parwanoo, Himachal Pradesh, in the age group of 16-55 years. Dental caries experience was assessed using WHO dentition status proforma (2013). Statistical analysis was done using SPSS 21.0. Results: Out of 1024 study subjects, 572 were males and 452 were females. Caries prevalence was found to be 47.46%. Mean decay-missing-filled teeth score of the population was 0.95 ± 0.45 and was found to be higher among females (1.06 ± 0.42) as compared to males (0.93 ± 0.38). Conclusion: The prevalence of dental caries in industrial workers is noteworthy. Essential requisites to bring this under control include awareness regarding good dental health, education on prevention of dental caries and implication of necessary measures for the provision of adequate dental care.

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Oral Health Status and Treatment Needs of Inmates in District Jail of Mathura City – A Cross Sectional Study

Journal of Oral Health and Community Dentistry ◽

10.5005/johcd-7-1-24 ◽

2013 ◽

Vol 7 (1) ◽

pp. 24-32 ◽

Cited By ~ 3

Author(s):

R Gupta ◽

K Dhanker ◽

NA Ingle ◽

N Kaur

Keyword(s):

Health Status ◽

Oral Health ◽

Dental Caries ◽

Public Health Problem ◽

Cross Sectional Study ◽

Oral Health Status ◽

Major Public Health Problem ◽

Sectional Study ◽

Treatment Needs ◽

Cross Sectional

ABSTRACT Objectives To assess the oral health status and treatment needs of inmates of, District Jail Mathura. MATERIALS AND METHODS A cross sectional study was carried out on the inmates (N=870) in the district jail of Mathura. Proforma related to general demographic information was filled by the examiner and the subjects were clinically examined using WHO 1997 “Oral Health Assessment Form RESULTS This study revealed that 92.5% of the inmates were male. 53.8% never visited the dentist & 87% never received any type of dental care during imprisonment. Prevalence of pro-mucosal lesion was 59.8%. Inmates had poor periodontal conditions and 79% inmates had dental caries with mean DMFT of 4.79. CONCLUSION Periodontal disease, mucosal lesions and dental caries are major public health problem among the inmates, which require special attention and efforts from government and other organizations to meet their treatment needs.

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Dental Caries Experience in 6-13 Years Old School Children of Dharan Sub-Metropolitan City, Nepal: A Cross-Sectional Study

Journal of Nepalese Association of Pediatric Dentistry ◽

10.3126/jnapd.v2i1.41559 ◽

2021 ◽

Vol 2 (1) ◽

pp. 12-18

Author(s):

Bhawana Sigdel Bastola ◽

Bandana Koirala ◽

Mamta Dali ◽

Sneha Shrestha ◽

Dharanidhar Baral

Keyword(s):

Risk Factors ◽

Oral Health ◽

Dental Caries ◽

School Children ◽

Cross Sectional Study ◽

Primary Dentition ◽

Caries Experience ◽

Sectional Study ◽

Cross Sectional ◽

Associated Risk Factors

Introduction: Dental caries though preventable oral health problem is affecting school children worldwide and around 50% of Nepalese children are suffering from it. Baseline data with good understanding of dental caries and associated risk factors are necessary to form preventive strategies for setting and achieving oral health goals. Objective: This study was conducted to determine dental caries experience and associated risk factors among school-going children of 6-13 years old in Dharan sub-metropolitan city, Nepal. Methods: A cross-sectional study was conducted from 5th Jan 2018 to 4th Jan 2019 among 680 school children selected by multistage cluster sampling method. Pretested, standardized, closed-ended questionnaire answered by the parents was used to gather information regarding the associated risk factors. Dental caries experience was obtained from deft/DMFT (WHO modification 1997). Comparison of categorical data was done using Chi-square test. Multivariable binary logistic regressions were used for the statistical analysis. Results: The overall caries prevalence was 61.6%, in primary dentition it was 48.25% and in permanent dentition it was 34.4%. Dental caries experience was with mean deft 4.67 (±2.7) in primary dentition and mean DMFT 1.72 (±1.05).in permanent dentition. Multivariate analysis showed significant association between dental caries experience and grade three and grade four school children had experienced greater caries (p<0.05, OR =2.7). Dental caries was associated with eating sweets at night (p<0.001, OR=2.5) and snacking in-between meals (p<0.001, OR=2.5). Conclusions: Dental caries among school-children in Dharan showed a significant burden especially within the primary dentition. It was significantly associated with factors like feeding habits -eating sweets in a day, eating sweets at night and snaking in between meals

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Knowledge on Childhood Dental Caries Among Parents of Under Five Children in A Community at Biratnagar, Nepal

Journal of Research and Development ◽

10.3126/jrdn.v4i3.39954 ◽

2021 ◽

Vol 4 (3) ◽

pp. 22-31

Author(s):

Sarmila Pradhan ◽

Deepika Khadgi ◽

Namita Yengden ◽

Karishma Khadgi

Keyword(s):

Dental Caries ◽

Public Health Problem ◽

Structured Interview ◽

Demographic Variables ◽

Good Knowledge ◽

Major Public Health Problem ◽

Cross Sectional ◽

Under Five ◽

Under Five Children ◽

Level Of Knowledge

Dental caries is a major public health problem globally and is one of the most chronic diseases in children. Children are susceptible to caries as soon as the first teeth appear. Parents are the primary decision-makers in matters of children's healthcare. If the parents are knowledgeable about the child's oral health care then childhood dental caries can be prevented. The objective of this study was to identify the knowledge on childhood dental caries among parents of under five children. A descriptive, cross-sectional study was carried out among parents of under five children in a community of Biratnagar 12. Sample was selected using non probability purposive sampling method and data was collected by face-to-face interview using a self-developed, semi-structured interview guideline. Descriptive statistics i.e. frequency, percentage, mean and standard deviation was used to assess the level of knowledge and inferential statistics i.e chi square was used to find the association between dependent and independent variables. About three fourths (71%) of the parents were of age group 20-30 years and 88% of them were mothers. Most of the parents (90%) were aware that dental caries can occur in under five children and excessive sugar intake was the most common cause as reported by all of them. Only 40% knew that dental caries is transmissible and among them 97.6% responded by sharing of toothbrush. Regarding good brushing habit, most of the parents were aware. Almost all (95%) knew that proper tooth brushing helps to prevent dental caries whereas only 19% were aware about use of fluoridated tooth paste as preventive measures. Meanwhile, only 12% of the parents were aware that first dental visit should be done when first tooth erupts or within 1 year of age More than half (79%) had good knowledge on childhood dental caries but there was no association of knowledge with socio-demographic variables. The study concluded that more than half of the respondents had good knowledge on childhood dental caries and none of the socio-demographic variables were associated with the level of knowledge of parents on dental caries. Despite good knowledge, prevalence of childhood dental caries is high in our society thus reflecting the need to assess the practice of dental care.

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Impact of untreated dental caries on oral health of adolescents from cities in the countryside of Rio Grande do Sul

Journal of Human Growth and Development ◽

10.7322/jhgd.152171 ◽

2018 ◽

Vol 28 (3) ◽

pp. 258-272

Author(s):

Paola Tibolla ◽

Lilian Rigo

Keyword(s):

Dental Caries ◽

Dental Treatment ◽

Public Health Problem ◽

Rio Grande ◽

Major Public Health Problem ◽

Rio Grande Do Sul ◽

Cross Sectional ◽

Untreated Caries ◽

Dmft Index ◽

Untreated Dental Caries

Introduction: Dental caries is a major public health problem around the world, because it can cause pain and suffering to individuals. Even with a decline in childhood disease in recent years, it is observed in many countries. Objective: The objective of this research is to analyze the mean of dental caries and the prevalence of untreated caries and associated factors in students from the southern region of Brazil. Methods: The approach of this study is quantitative, with a cross-sectional design. The research sample was composed of 77 adolescents from the state schools of the urban area of the municipalities of Ciríaco and David Canabarro, Rio Grande do Sul, Brazil. For the data collection, clinical exams were performed, using the DMFT index, and the application of two semistructured questionnaires to adolescents and their parents. The data were analyzed by descriptive statistics and inferential statistics to the Pearson chi-square test and ANOVA at a significance level of 5%. Results: The prevalence of untreated dental caries in the final sample was 40.3% and the DMFT index (decayed, missing and filled teeth) 2.32, there was no statistical difference between cities. There was a statistically significant relationship between the variable toothache in the last six months and the outcome of untreated caries (p = 0.012) with 76% of those who had pain. There was also an association between the variable perception of the treatment at the last visit and untreated caries (p = 0.021), with 84.6% of adolescents considering poor / regular treatment. Conclusion: Although the average dental caries has been low, many adolescents have decayed and untreated teeth, with toothache and lack of quality in dental treatment being the factors that most impacted.

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The potential impact of age, gender, body mass index, socioeconomic status and dietary habits on the prevalence of dental caries among Egyptian adults: a cross-sectional study

F1000Research ◽

10.12688/f1000research.17892.1 ◽

2019 ◽

Vol 8 ◽

pp. 243 ◽

Cited By ~ 4

Author(s):

Marwa M.S. Abbass ◽

Nermeen AbuBakr ◽

Israa Ahmed Radwan ◽

Dina Rady ◽

Sara El Moshy ◽

...

Keyword(s):

Risk Factors ◽

Body Mass Index ◽

Dental Caries ◽

Body Mass ◽

Dietary Habits ◽

Demographic Data ◽

Public Health Problem ◽

Education Level ◽

Caries Experience ◽

Major Public Health Problem

Background:Dental caries is a major public health problem and the most widespread chronic disease to affect individuals throughout their lifetime. Little information exists about the prevalence of dental caries among Egyptian adults. Therefore, this study investigated the dental caries experience among Egyptian adults in correlation with different risk factors.Methods:A total of 359 Egyptian adults (age range, 18-74 years) were examined over a period of 3 months, starting on the 15thof November 2017 until the 13thof January 2018. Socio-demographic data, brushing frequency, body mass index (BMI) and eating habits were recorded and collected using a questionnaire. Dental examination was performed using the Decayed, Missing and Filled tooth (DMFT) index.Results:In total, 86.63% of participants had dental caries experience. Of the participants, 60.45%, 48.47% and 55.43% had at least one decayed, missing and filled tooth, respectively. The mean number of decayed, missing, filled or DMFT for the whole sample were 2.4±3.6, 1.98±3.99, 1.79±2.45, 6.09±5.7, respectively. Decayed teeth were inversely correlated with socio-economic status (SES), education level, brushing frequency and milk consumption and positively correlated with grains, junk food and soda drinks consumption. Missing teeth were inversely correlated with SES, education level and brushing frequency, while positively correlated with age, BMI and caffeinated drink consumption. Conversely, filled teeth were positively correlated with age, BMI, SES and education level, while negatively correlated with grains and sugars in drinks.Conclusion:The present study clarifies that age, BMI, SES, education level and brushing frequency are risk factors significantly associated with dental caries prevalence amongst Egyptian adults. Egyptian adults' dietary habits might lead to obesity, which indirectly causes dental caries rather than directly as in children.

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Validation and Psychometric Properties of the Spanish Version of the Hopkins Symptom Checklist-25 Scale for Depression Detection in Primary Care

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18157843 ◽

2021 ◽

Vol 18 (15) ◽

pp. 7843

Author(s):

María Rodríguez-Barragán ◽

María Isabel Fernández-San-Martín ◽

Ana Clavería-Fontán ◽

Susana Aldecoa-Landesa ◽

Marc Casajuana-Closas ◽

...

Keyword(s):

Primary Care ◽

Psychometric Properties ◽

Public Health Problem ◽

Composite International Diagnostic Interview ◽

Spanish Version ◽

Major Public Health Problem ◽

Symptom Checklist ◽

Validity And Reliability ◽

Cross Sectional ◽

Hopkins Symptom Checklist

Depression constitutes a major public health problem due to its high prevalence and difficulty in diagnosis. The Hopkins Symptom Checklist-25 (HSCL-25) scale has been identified as valid, reproducible, effective, and easy to use in primary care (PC). The purpose of the study was to assess the psychometric properties of the HSCL-25 and validate its Spanish version. A multicenter cross-sectional study was carried out at six PC centers in Spain. Validity and reliability were assessed against the structured Composite International Diagnostic Interview (CIDI). Out of the 790 patients, 769 completed the HSCL-25; 738 answered all the items. Global Cronbach’s alpha was 0.92 (0.88 as calculated for the depression dimension and 0.83 for the anxiety one). Confirmatory factor analysis (CFA) showed one global factor and two correlated factors with a correlation of 0.84. Area under the curve (AUC) was 0.89 (CI 95%, 0.86–0.93%). For a 1.75 cutoff point, sensibility was 88.1% (CI 95%, 77.1–95.1%) and specificity was 76.7% (CI 95%, 73.3–79.8%). The Spanish version of the HSCL-25 has a high response percentage, validity, and reliability and is well-accepted by PC patients.

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Free Sugars Intake among Chinese Adolescents and Its Association with Dental Caries: A Cross-Sectional Study

Nutrients ◽

10.3390/nu13030765 ◽

2021 ◽

Vol 13 (3) ◽

pp. 765

Author(s):

Qiping Yang ◽

Yue Xi ◽

Hanmei Liu ◽

Jing Luo ◽

Yufeng Ouyang ◽

...

Keyword(s):

Oral Health ◽

Dental Caries ◽

Cross Sectional Study ◽

Chinese Adolescents ◽

Food Sources ◽

Caries Experience ◽

Sectional Study ◽

Cross Sectional ◽

Free Sugars ◽

Targeted Interventions

This study aims to estimate the free sugars intake, identify the primary food sources of free sugars, and explore the relationship between free sugars intake and dental caries among Chinese adolescents. This cross-sectional study included 1517 middle-school students aged 12–14 years in Changsha city, China. Adolescents completed a 12-item Food Frequency Questionnaire (FFQ) and oral health assessment. The students’ dental caries experience was available as DMFT score (number of decayed, missing, and filled permanent teeth). Statistical analyses included the Mann–Whitney test, Kruskal–Wallis test, Chi-square test, and binary logistic regression model. The average intake of free sugars was 53.1 g/d in adolescents, and 43.2% of the students consumed more than 50 g of free sugars daily. The primary contributor to free sugars was sugar-sweetened beverages (SSBs). Age, boarders, and high family income were risk factors for excessive free sugars intake (p < 0.05), and increased free sugars intake was a risk factor for dental caries (odds ratio, OR = 1.446, 95% confidence interval: 1.138–1.839). Both the free sugars intake and dental caries prevalence in Chinese adolescents were high. Targeted interventions are urgently needed to address the excessive consumption of free sugars and improve Chinese adolescents’ oral health.

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The prescription pattern and awareness about antibiotic prophylaxis and resistance among a group of Egyptian pediatric and general dentists: a cross sectional study

BMC Oral Health ◽

10.1186/s12903-021-01685-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Mariam Mohsen Aly ◽

Marwa Aly Elchaghaby

Keyword(s):

Antibiotic Resistance ◽

Antibiotic Prophylaxis ◽

Antibiotic Prescription ◽

Public Health Problem ◽

Cross Sectional Study ◽

Major Public Health Problem ◽

Eligibility Criteria ◽

Cross Sectional ◽

Validated Questionnaire ◽

General Dentists

Abstract Background The use of antibiotics in dentistry as prophylaxis and treatment is frequent. Their misuse has led to a major public health problem globally known as antibiotic resistance. This study aimed to assess the pattern of antibiotic prescription and its prophylactic use for systemic conditions. Besides, this study evaluated the awareness and adherence to antibiotic prescription guidelines and antibiotic prophylaxis guidelines along with awareness of antibiotic resistance across pediatric and general dentists. Methods An overall of 378 pediatric and general dentists meeting the required eligibility criteria, fulfilled a pre-designed validated questionnaire. Data were collected, tabulated, and statistically analyzed. Results A significant statistical difference was found among the pediatric and general dentists regarding antibiotics prescription for most of the oral conditions where Amoxicillin with clavulanic acid was the most frequently prescribed antibiotic among the two groups (53% pediatric dentist and 52% general dentist). The majority of pediatric and general dentists, on the other hand, were aware of antibiotic resistance and prescribing recommendations. Conclusions The present study showed a tendency to overprescribe and overuse antibiotics in certain dental conditions among the participants. The vast majority of dentists, especially general dentists do not have adherence to professional guidelines for antibiotics prescription in children despite their awareness of antibiotic resistance and prescription guidelines.

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Predictive risk factors towards liver fluke infection among the people in Kamalasai District, Kalasin Province, Thailand

SAGE Open Medicine ◽

10.1177/2050312119840201 ◽

2019 ◽

Vol 7 ◽

pp. 205031211984020 ◽

Cited By ~ 1

Author(s):

Woragon Wichaiyo ◽

Wirat Parnsila ◽

Wisit Chaveepojnkamjorn ◽

Banchob Sripa

Keyword(s):

Risk Factors ◽

Liver Fluke ◽

Public Health Problem ◽

Major Public Health Problem ◽

Cross Sectional ◽

The People ◽

Fluke Infection ◽

Raw Fish ◽

Predictive Risk ◽

Liver Fluke Infection

Background: Liver fluke disease caused by Opisthorchis viverrini remains a major public health problem with its crucial risk factors caused by some individual habits or false beliefs among the people in northeastern Thailand concerning the consumption of raw fish meat dishes. Objectives: This study explores the predictive risk factors for the infection of liver fluke disease. Methods: The sample consisted of 400 people aged 30 years and above in Thanya sub-district, Kamalasai district, Kalasin province. A cross-sectional analytic study, using the χ2 test, odds ratio and 95% confidence interval, was used to find the influence of each variable, along with the use of multiple logistic regression (p = 0.05). A questionnaire form was used as the research instrument. Results: Factors found in the results are as follows: households with a cat were 7.00 times more at risk than households without a cat; eating raw fish dishes prepared by themselves increases the risk of infection by 2.58 times; eating raw fish dishes prepared by family members increases the risk by 4.74 times; and raw fish dishes bought from a community market increases the risk by 2.33 times. Conclusion: A campaign should be launched to educate people not to eat raw or undercooked fish dishes, but to fully cook fish dishes before eating, as the food is still delicious, but also safe, healthy, and free from liver fluke infection.

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