Fever as a Side Effect after Electroconvulsive Therapy

2021 ◽  
pp. 1-9
Author(s):  
Young Tak Jo ◽  
Jungsun Lee ◽  
Yeon Ho Joo
Keyword(s):  
Electroconvulsive Therapy ◽  
Side Effect ◽  
Medical Center ◽  
Common Side Effect ◽  
Control Group ◽  
Nonpharmacological Treatment ◽  
Unexplained Fever ◽  
Asan Medical ◽  
Patients Experience ◽  
And Control

<b><i>Background:</i></b> Electroconvulsive therapy (ECT) is the most important and safe nonpharmacological treatment for psychiatric disorders. Some patients experience unexplained fever after ECT, but only a few studies have reported on this. <b><i>Method:</i></b> We investigated fever after ECT by retrospectively reviewing the medical records of patients. Patients treated at the ECT unit of the Department of Psychiatry at Asan Medical Center, Seoul, South Korea, between 30 June 2004 and 30 June 2019, were included. Differences in variables were compared between groups with or without fever after ECT sessions. <b><i>Result:</i></b> There were 28 patients (8.8%) in the fever group. Forty-three ECT sessions (1.5%) resulted in fever after treatment. The female-to-male ratio was higher in the fever group than in the control group, and the mean number of total ECT sessions was also higher in the fever group than in the control group, but there were no other differences between the 2 groups. <b><i>Conclusion:</i></b> Comparing fever and control sessions, fever sessions relatively preceded control sessions and had a longer seizure duration. Postictal delirium occurred more often in the fever sessions than in control sessions. Fever sessions had a higher white blood cell count and lower concomitant quetiapine dosage than control sessions. Because 8.8% of patients who received ECT experienced fever after treatment more than once, fever after ECT is considered to be a common side effect.

Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome

2019 ◽  
pp. 68-73
Author(s):  
Trong Nghia Nguyen ◽  
Thi Nhan Nguyen ◽  
Thi Dua Dao
Keyword(s):  
Metabolic Syndrome ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D ◽  
Key Words Metabolic Syndrome ◽  
And Control

Background: The metabolic syndrome is a constellation of cardiometabolic risk factors that tend to cluster together in affected individuals more often than predicted by chance. The presence of the metabolic syndrome substantially increases the risk of developing type 2 diabetes and cardiovascular disease, and is associated with a range of adverse clinical outcomes, many of which are closely associated with aging. Current estimates suggest that approximately 20 - 25% of the world’s population is affected by the metabolic syndrome. The prevalence of the metabolic syndrome rises with age and more than 45% of people aged over 60 years have the metabolic syndrome. Recent studies show that low vitamin D status is very common in the world and this is a risk factor of metabolic syndrome. Objective: (1) Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome. (2) Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Material and method: A cross-sectional study with control group on 318 adult subjects for health examinations at International Medical Center at Hue Central Hospital, including 139 subjects with metabolic syndrome and control group of 179 healthy subjects. Metabolic syndrome was defined according to the IDF, NHLBI, AHA, WHF, IAS, IASO (2009). Plasma hydroxyvitamin D concentration was measured using chemiluminescent microparticle immunoassay. Reciever operating characteristic (ROC) curve were generated to assess sensitivity and specificity for different cut off value of 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Results: Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome was 26.4 ng/ml, incidence of plasma 25-hydroxyvitamin D deficiency (59.7%) was significantly higher than in control group (23.5%) (p < 0.001). The optimal cut off point for 25-OH-D concentration for predictor of metabolic syndrome as 26.4 ng/ml (AUC=0.657, sensitivity=53.4%, specificity=71.6%). Conclusion: In 139 subjects with metabolic syndrome, the plasma 25-hydroxyvitamin D concentration was 26.4 ng/ml and the incidence of 25-hydroxyvitamin D deficiency in the metabolic syndrome group was 59.7%. The optimal cut off point for plasma 25-hydroxyvitamin D concentration for predictor of metabolic syndrome as 26.4 ng/ml. Key words: Metabolic syndrome, 25-hydroxyvitamin D

scholarly journals THE EFFECT OF VIRGIN COCONUT OIL AGAINST SKIN TREATMENT OF LEPROSY PATIENTS

2019 ◽  
pp. 259-261
Author(s):  
ZUHRIANA K YUSUF ◽  
NANANG R PARAMATA ◽  
WIRDA Y DULAHU
Keyword(s):  
Coconut Oil ◽  
Control Group ◽  
Virgin Coconut Oil ◽  
Permanent Disability ◽  
Alternative Intervention ◽  
Post Test ◽  
Leprosy Patients ◽  
Patients Experience ◽  
And Control ◽  
Therapy Treatment

Objective: Leprosy is a major cause of permanent disability among infectious diseases. The important parts of the human body that is disturbed in leprosy patients are the skin and peripheral nerves. Multidrug therapy treatment can kill leprosy germs, but previous existing defects cannot be eliminated. The purpose of this study was to determine the effectiveness of virgin coconut oil (VCO) in improving the skin of lepers. Methods: The methods of this research used a pre- and post-test of the control group of 50 people respondents which consisted of the treatment group of VCO and control group of original coconut oil. All treatment and control groups of respondents were given once per day for 1 month based on non-probability sampling. Results: The results showed that there was a significant effect of VCO on the skin of leprosy patients with a statistical value p=0.000 (α=0.001). This was also supported by the observation of the patient’s skin which all of patients experience changed in the results of the assessment of the skin after VCO administration intervention. This relates to lauric acid content in coconut oil which can reduce skin moisture levels. Conclusion: Based on the results of this study can be concluded that VCO is effective in improving the skin of lepers. VCO can be used as an alternative intervention in skin care for leprosy patients and to prevent further disability. Therefore, it is important for leprosy patients to obtain information about the use of VCO in the care and moisture of the skin.

scholarly journals A Single Virtual Consult Reduces Severe Hyperglycemia in Patients Admitted with COVID19 Infection

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A335-A335
Author(s):  
Diana Athonvarangkul ◽  
Felona Gunawan ◽  
Kathryn Nagel ◽  
Leigh Bak ◽  
Kevan C Herold ◽  
...  
Keyword(s):  
Medical Center ◽  
Academic Medical Center ◽  
Control Group ◽  
Post Intervention ◽  
Academic Medical ◽  
Treatment Plans ◽  
The Mean ◽  
Glucose Management ◽  
And Control ◽  
Glycemic Management

Abstract Diabetes and hyperglycemia are risk factors for morbidity and mortality in hospitalized patients with COVID19. Subspecialty consultative resources to help front-line clinicians treat these conditions is often limited. We implemented a “Virtual Hyperglycemia Surveillance Service (VHSS)” to guide glucose management in COVID19 patients admitted to our 1541-bed academic medical center. From April 22 to June 9, 2020, hospitalized adult patients with COVID19 and 2 or more blood glucose (BG) values greater than 250 mg/dl over 24-h were identified using a daily BG report. The VHSS reviewed BGs and treatment plans, then made recommendations for future glycemic management via a one-time note, visible to all providers. Some patients with re-admission or persistently elevated BG after 1 week received a second VHSS note. We compared BGs from 24-h pre- and 72-h post-intervention starting at 6AM on the day following VHSS review. We also evaluated for hypoglycemia, insulin infusion use and use of formal diabetes consults. A subgroup analysis was performed on patients in the intensive care unit (ICU). At the end of the intervention, we identified a retrospective control cohort admitted to the same hospital from March 21 to April 21, 2020 who met the inclusion criteria for a VHSS assessment. The VHSS group consisted of 100 patients with 126 individual VHSS encounters, and the control group comprised 50 patients. Baseline characteristics in the VHSS and control groups, respectively, were: mean age 62.5 vs 62.1 years, % male 58 vs 56, mean weight 91.4 vs 93.4 kg, BMI 31.8 vs 33.0 kg/m2, and HbA1c 9.1 vs 8.8 %. There were fewer patients in the ICU in the VHSS than control group (44% vs 66%). In the VHSS group, mean BG pre- vs. post-intervention was 260.3 ±21.7 and 227.4 ±25.3 mg/dl (p&lt;0.001). In the control group, mean BG pre-and post- the day they met assessment criteria was 264.8 ± 6.5 mg/dl and 250.6 ± 8.6 mg/dl (p=0.18). There was no difference in the use of insulin infusions or diabetes consults between the two groups. More hypoglycemia (BG&lt;70 mg/dl) occurred in the VHSS than control group (8.3% vs 0%, p=0.04). Within the VHSS group, the average change in BG was significantly greater in ICU than non-ICU patients (-51.8 ±8.7 vs -19.6 ±5.0 mg/dl, p&lt;0.01) and the reduction in the % of BG over 250 mg/dl was also significantly greater in the ICU (-32.2% vs -16.8%, p=0.02). Implementation of a single virtual consult for severely hyperglycemic hospitalized COVID19 patients was associated with rapidly reduced BG concentrations, especially in the ICU. The mean reduction in BG with VHSS intervention was more than 2-fold greater than that observed in our control group. Glucose control remained suboptimal, however, suggesting the need for subsequent input from this specialty service.

scholarly journals Effect of TRH on beta-gonadotropin subunits in patients with pituitary microincidentalomas

1999 ◽  
pp. 17-21 ◽  
Author(s):  
Y Greenman ◽  
Y Trostanetsky ◽  
D Somjen ◽  
K Tordjman ◽  
F Kohen ◽  
...  
Keyword(s):  
Medical Center ◽  
Adult Population ◽  
Control Group ◽  
Beta Subunits ◽  
Similar Response ◽  
Control Groups ◽  
Trh Stimulation ◽  
Pituitary Incidentaloma ◽  
Abnormal Increase ◽  
And Control

OBJECTIVE: To explore the hypothesis that most of the pituitary abnormalities compatible with the diagnosis of microadenoma, and detected in about 10% of the normal adult population, represent asymptomatic gonadotropinomas. DESIGN: Patients diagnosed with pituitary microincidentalomas at the Institute of Endocrinology of the Tel Aviv Medical Center were evaluated. Circulating beta-subunits of gonadotropin hormones were measured before and 30, 45, 60 and 90 min after the intravenous injection of 400 microgram TRH. PATIENTS: Twenty-two patients with pituitary incidentaloma and 16 normal volunteers were tested. RESULTS: In 16 of the 22 patients, an abnormal beta-subunit response was detected after the TRH challenge. Three patients had an abnormal increase in both beta-FSH and beta-LH after TRH administration. Isolated pathological beta-FSH or beta-LH responses were demonstrated in five and eight patients respectively. Six patients had normal basal and stimulated gonadotropin subunit values, raising the possibility that their lesions were not pituitary microadenomas. There was a significant overall difference between the response to TRH of the patient and control groups. In the gonadotropin positive group, comprising 16 patients, serum beta-FSH increased from 6.4+/-1.6 ng/ml to 9.2+/-1.3 ng/ml (P=0.042) 1 h after TRH stimulation, whereas no changes were detected in the control group after TRH injection (basal: 4.1+/-0.8 ng/ml, peak: 5.1+/-0.8 ng/ml; P=0.15). Serum beta-LH increased from 10.5+/-3.2 ng/ml to 23.4+/-4.9 ng/ml (P=0.0037) at this time, in contrast to a lack of response in controls (basal: 6.4+/-1.5 ng/ml, peak: 8.2+/-2.3 ng/ml; P=0.24). CONCLUSION: In about 73% of patients with pituitary incidentalomas smaller than 10 mm, TRH elicits an increase in gonadotropin beta-subunits. This observation raises the possibility that non-functioning pituitary micro- and macroadenomas, which share a similar response to TRH, originate in a common ancestor cell type, probably a pituitary gonadotrope.

scholarly journals Aromatherapy Ginger Use in Patients with Nausea & Vomiting on Post Cervical Cancer Chemotherapy

2017 ◽  
Vol 13 (1) ◽  
pp. 59-68 ◽  
Author(s):  
Iis Sriningsih ◽  
Elisa Elisa ◽  
Kurniati Puji Lestari
Keyword(s):  
Cervical Cancer ◽  
Cancer Chemotherapy ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Measurement Tool ◽  
Control Group Design ◽  
Significant Difference ◽  
Before And After ◽  
Patients Experience ◽  
And Control

Chemotherapy is an effective treatment for cancer. However, it causes some side effects which include nausea and vomiting. More than 70% of patients experience nausea and vomiting after chemotherapy. The purpose of this study was to determine the effect of ginger aromatherapy in nausea, and vomiting patients on post cervical cancer chemotherapy. We used a pretest-posttest control group design, using purposive sampling of 60 respondents. We used anti-emetics measurement tool according to Multinational Association of Supportive Care in Cancer (MASCC) to assessed patients complaints. The result showed significant difference in nausea and vomiting group before and after given aromatherapy (p = 0.000); nausea score (p = 0.005) and vomiting score (p= 0.013) from intervention and control group. No significant difference was observed in nausea (p = 0.279), and vomiting (p = 0.276) on control group. Ginger aromatherapy can be used as alternative medication to reduce post-chemotherapy nausea and vomiting.

Deprescribing Medications Among Older People to Reduce Polypharmacy at a Comprehensive Academic Medical Center

2021 ◽  
Vol 36 (4) ◽  
pp. 208-216
Author(s):  
Stella Ye ◽  
Sarah Boyko ◽  
Melissa Patel ◽  
Kruti Shah ◽  
Sara Turbow ◽  
...  
Keyword(s):  
Older People ◽  
Acute Care ◽  
Medical Center ◽  
Academic Medical Center ◽  
The Elderly ◽  
Control Group ◽  
Control Groups ◽  
Care For The Elderly ◽  
Academic Medical ◽  
And Control

OBJECTIVE: To evaluate deprescribing of select high-risk medications (HRMs) in an Acute Care for the Elderly (ACE) unit with pharmacist involvement compared with usual care in older people. DESIGN: Retrospective, single-center case-control study. SETTING: Medical-surgical units at an urban academic medical center. PARTICIPANTS: Patients 65 years of age and older admitted April-June 2019, with 1 or more of the following target HRMs prior to admission were included in the study: acid suppressants, antipsychotics, or insulin. Patients admitted to the ACE unit were included in the case group; all other patients were randomly matched by HRMs in a 2:1 ratio into the control group. INTERVENTIONS: The Acute Care for the Elderly pharmacist reviewed patients' medications to identify and deprescribe select HRMs. Deprescribing was defined as discontinuation, dose or frequency reduction. RESULTS: A total of 47 patients with 56 HRMs and 89 patients with 126 HRMs were included in the case and control groups, respectively. The primary outcome of HRMs deprescribed were similar between the case and control groups (21.4% and 25.4%; P = 0.56). Among the HRMs deprescribed (discontinued, dose or frequency reduced), 83.2% were complete discontinuations in case patients and 34.4% were complete discontinuations in control patients.

Effects of desmopressin (DDAVP) on memory impairment following electroconvulsive therapy (ECT)

2004 ◽  
Vol 16 (3) ◽  
pp. 130-137
Author(s):  
Ebrahim Abdollahian ◽  
Mohammad R. Sargolzaee ◽  
Moosareza Hajzade ◽  
Mohammad D. Mohebbi ◽  
Arash Javanbakht
Keyword(s):  
Electroconvulsive Therapy ◽  
Memory Impairment ◽  
Memory Function ◽  
Common Adverse Effect ◽  
Common Side Effect ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Case Group ◽  
Positive Effects ◽  
The Third

Background:Memory impairment is a common adverse effect of electroconvulsive therapy (ECT). Studies on animals and humans suggest that vasopressin improves the cognitive function, and positive effects of desmopressin on memory and learning have been reported. This research was performed for evaluation of the effects of desmopressin in the prevention of memory impairment following ECT.Methods:This randomized, double-blind controlled clinical trial with placebo administration was performed on 50 patients with psychiatric disorders who were candidates for ECT. Subjects in the case group received 60 µm of intranasal desmopressin daily (in three doses of 20 µm). For the control group 0.9% saline solution was administered in the same way. Memory function was evaluated using Wechsler's Memory Scale three times a week (the first time before the start of ECT and the second and third times after the third and sixth sessions, respectively). Results were analyzed by t-test and Paired t-test.Results:The mean age of patients was 29 years (range 20–40). During the course of ECT, patients in the control group demonstrated a meaningful decrease in memory scores (from a base score of 80.15–75.45 in the second test and 72.60 in the third test). Despite this, a meaningful increase in memory scores was observed during the treatment with desmopressin in the case group (from a base score of 73.27–75.70 and 79.13 in the second and the third tests, respectively). There was a meaningful difference between the two groups (P < 0.0001).Conclusion:This study confirms the protective effect of desmopressin against memory impairment. The results confirm that memory impairment is a common side-effect of ECT and suggest that desmopressin may prevent ECT-induced memory impairment by its effects on memory and the learning process.

scholarly journals Prospective Cohort Study on the Effect of an Intervention to Reduce Household Air Pollution Among Sudanese Women and Children

2021 ◽  
Vol 11 (31) ◽  
Author(s):  
Alawia K Suliman ◽  
Maysoon M. Saleh ◽  
Kristin Sznajder ◽  
Tonya S. King ◽  
W. Stuart Warren
Keyword(s):  
Air Pollution ◽  
Low Socioeconomic Status ◽  
Medical Center ◽  
Household Air Pollution ◽  
Health Concern ◽  
Control Group ◽  
Study Group ◽  
Biomass Fuels ◽  
Women And Children ◽  
And Control

Background. Exposure to household air pollution through the burning of biomass fuels is a global health concern and can lead to negative health outcomes such as asthma and lung disease. Objectives. The goal of this four-year study was to determine whether an intervention to reduce household air pollution (HAP) which included health education and a new well-ventilated cooking location would reduce exposure to HAP, lower carbon monoxide (CO) levels and improve the health of women and children in Port Sudan, Sudan. Methods. In 2016, 115 women of low socioeconomic status and their children were invited to participate in the study at two women's centers. One hundred and eleven women consented to participate and were divided into study and control groups on the basis of home ownership. Women who owned their homes learned about the adverse effects of HAP and a well-ventilated outside cooking location (rakoobah) was provided. Control women did not receive HAP education or a rakoobah. Questionnaires were used to assess the effect of education and a new well-ventilated cooking location for a group of Sudanese women who cook with biomass fuels. CO-oximetry was performed. Each year from 2017–2019, the questionnaires and CO-oximetry were repeated. Results. Sixty-five women and 33 children were assigned to the study group and 46 women and 19 children were assigned to the control group in 2016. Women were enrolled in 2016 with CO levels of 17.8% and 17.4%, respectively. One year later some of the study group women had lower CO levels and others higher, while the CO levels of the controls were stable. An intensive HAP education program was started for the study group women. By 2019, the last study year, the CO levels of both the study and control group women had dropped to normal levels of 2.9% and 3.1%, respectively. Control group women may have benefited from the HAP education and modeled behavior of those in the study group. Conclusions. The health impact of the change in cooking location was unclear, yet both groups reported fewer health care visits in 2019. Education and an outside cooking location resulted in lower CO levels of Sudanese women and children. Participant Consent. Obtained Ethics Approval. The study was approved by the Penn State Milton S. Hershey Medical Center Institutional Review Board and the Ethics Committee of the Red Sea University Faculty of Medicine located in Port Sudan, Sudan. Competing Interests. The authors declare no competing financial interests.

scholarly journals The Effect of Oral Pregabalin on Epidural-Induced Shivering and Epidural Characteristics in Gynecological Surgeries, a Prospective Randomized Double-Blind Study

2018 ◽  
Author(s):  
Tarek Al Menesy ◽  
Ghada Adel ◽  
Ahmed A. Badawy ◽  
Samaa A. Kasem ◽  
Ashraf Abd Elmawgoud ◽  
...  
Keyword(s):  
Side Effects ◽  
Epidural Anesthesia ◽  
Side Effect ◽  
Epidural Block ◽  
Control Group ◽  
Double Blind Study ◽  
Single Shot ◽  
Double Blind ◽  
Sedation Scores ◽  
And Control

Abstract Purpose: The previous reports tried to reduce shivering and improve neuraxial anesthesia characteristics by the systemic use of different drugs. This study was directed to evaluate the effect of pregabalin premedication on both shivering and epidural characteristics following single shot loading. Patients and Methods: Eighty female patients, ASA grade I and II, scheduled for gynecological surgeries under epidural anesthesia were studied. The patients were divided into two groups: Pregabalin (P) group and Control (C) group in which the patients received 150 mg of pregabalin and placebo capsules respectively sixty minutes prior to surgery. Following epidural loading, the onset and degree of shivering were compared between the two groups. Also, the epidural onset, level and duration were compared. The perioperative hemodynamics, sedation scores, meperidine consumption and side effects were followed up and registered. Results: The onset of shivering was significantly prolonged and the degree of shivering was less in pregabalin group compared to Control group. The duration of epidural shot was shorter in the control group in relation to the pregabalin treated patients. Regarding both onset and level of block, no significant changes were detected. The patients were more sedated with less meperidine consumption in the pregabalin group. The two groups were similar as regards the perioperative hemodynamics and occurrence of side effect. Conclusion: The premedication with pregabalin reduced onset and degree of shivering and prolonged the duration of single shot epidural block.

The self and schizophrenia: a cognitive approach

2003 ◽  
Vol 62 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Marek Nieznanski
Keyword(s):  
Normal Subjects ◽  
Control Group ◽  
Cognitive Approach ◽  
Schizophrenic Patients ◽  
Self Schema ◽  
Persons With Schizophrenia ◽  
Basic Features ◽  
Trait Words ◽  
Patients Experience ◽  
Normal Controls

The aim of the study was to explore the basic features of self-schema in persons with schizophrenia. Thirty two schizophrenic patients and 32 normal controls were asked to select personality trait words from a check-list that described themselves, themselves as they were five years ago, and what most people are like. Compared with the control group, participants from the experimental group chose significantly more adjectives that were common to descriptions of self and others, and significantly less that were common to self and past-self descriptions. These results suggest that schizophrenic patients experience their personality as changing over time much more than do healthy subjects. Moreover, their self-representation seems to be less differentiated from others-representation and less clearly defined than in normal subjects.

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