scholarly journals Yellow fever: profile of cases and factors associated with death in a hospital in the State of Rio de Janeiro, 2017–2018

2019 ◽  
Vol 53 ◽  
pp. 89 ◽  
Author(s):  
Claudia Caminha Escosteguy ◽  
Alessandra Gonçalves Lisbôa Pereira ◽  
Marcio Renan Vinícius Espínola Marques ◽  
Tatiana Rodrigues de Araujo Lima ◽  
Rafael Mello Galliez ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Multivariate Analysis ◽  
Yellow Fever ◽  
Rio De Janeiro ◽  
Renal Excretion ◽  
Laboratory Data ◽  
Elevated Serum ◽  
The State ◽  
Factors Associated ◽  
Clinical Records

OBJECTIVE: Describe the clinical and epidemiological profile of confirmed cases of yellow fever whose patients were hospitalized in a general hospital for infectious diseases in the State of Rio de Janeiro, Brazil, from March 11, 2017 to June 15, 2018, during a recent outbreak and factors associated with death. METHODS: This is a retrospective observational study with analysis of secondary databases of local epidemiological surveillance system, and complementary data collection from epidemiological investigation records and clinical records. Study variables included demographic, epidemiological, clinical, and laboratory data. A descriptive statistical analysis and a bivariate and multivariate analysis by logistic regression were performed to analyze factors associated with death. RESULTS: Fifty-two patients diagnosed with yellow fever were hospitalized, 86.5% male patients, median age 49.5 years, 40.4% rural workers. The most frequent signs and symptoms were fever (90.4%), jaundice (86.5%), nausea and/or vomiting (69.2%), changes in renal excretion (53.8%), bleeding (50%), and abdominal pain (48.1%), with comorbidity in 38.5% of all cases. The lethality rate was 40.4%. Factors significantly associated with a higher chance of death in the bivariate analysis were: bleeding, changes in renal excretion, and maximum values of direct bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, and creatinine. In the multivariate analysis by logistic regression, only changes in renal excretion and ALT remained significant predictors of higher chance of death. A threshold effect was also observed for AST. The cutoff points identified as high risk for death were ALT > 4,000 U/L and AST > 6,000 U/L. CONCLUSIONS: This study contributed to the knowledge on the profile of confirmed cases of high severity yellow fever. The main factors associated with death were changes in renal excretion and elevated serum transaminases, especially ALT. High lethality emphasizes the need for early diagnosis and treatment, and the importance of increasing vaccination coverage.

Anorectal pathology amongst HIV infected patients attending the Douala General Hospital: a cross-sectional study

2016 ◽  
Vol 28 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Henry Namme Luma ◽  
Servais Albert Fiacre Bagnaka Eloumou ◽  
Ellis Atemlefeh Fualefeh-Morfaw ◽  
Agnes Malongue ◽  
Elvis Temfack ◽  
...  
Keyword(s):  
Logistic Regression ◽  
General Hospital ◽  
Laboratory Data ◽  
Study Participant ◽  
Cross Sectional Study ◽  
Interquartile Range ◽  
People Living With Hiv ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

While gastrointestinal disease is common among HIV infected individuals, the prevalence and distribution of ano-rectal pathology has not been well studied in our setting. The objective of this study therefore was to determine the prevalence and determinants of ano-rectal pathology in HIV infected patients attending the Douala General Hospital HIV treatment centre. A hospital-based cross-sectional study was undertaken. We collected socio-demographic, clinical and laboratory data using a structured questionnaire and patients’ files. Each study participant had a full physical and ano-rectal examination. We further studied factors associated with having at least one ano-rectal lesion by logistic regression reporting odds ratios (ORs) and their 95% confidence intervals (CI). We included 390 HIV infected patients. The mean age was 41 (SD: 8) years and 48% were men. Median duration since HIV diagnosis was 3 (interquartile range: 2–5) years and median CD4 cell count was 411 (interquartile range: 234–601) cells/mm3. Prevalence of ano-rectal pathology was 22.8% (95% CI: 18.7–27.3). Hemorrhoids and proctitis were most common lesions found; each in 10% of patients. From multivariate logistic regression, factors associated with ano-rectal pathology were CD4 < 350 cells/ml (OR: 2.1, 95% CI: 1.1–4.2), not on highly active antiretroviral therapy (OR: 2.2, 95% CI: 1.1–4.6), inpatient (OR: 2.3, 95% CI: 1.2–4.3), ano-rectal intercourse (OR: 5.0, 95% CI: 1.7–15.1), and more than one sexual partner (OR: 2.4, 95% CI: 1.3–4.2). Ano-rectal pathology is common amongst HIV infected patients. Care givers should actively investigate and treat them as this will improve the quality of life of people living with HIV/AIDS.

scholarly journals Prevalence and factors associated with nutritional deviations in women in the pre-pregnancy phase in two municipalities of the State of Rio de Janeiro, Brazil

2014 ◽  
Vol 17 (1) ◽  
pp. 45-58 ◽  
Author(s):  
Daniele Marano ◽  
Silvana Granado Nogueira da Gama ◽  
Rosa Maria Soares Madeira Domingues ◽  
Paulo Roberto Borges de Souza Junior
Keyword(s):  
Rio De Janeiro ◽  
Multinomial Logistic Regression ◽  
First Trimester ◽  
Overweight And Obesity ◽  
The State ◽  
The Body ◽  
Nutritional Risk ◽  
Institute Of Medicine ◽  
Cross Sectional ◽  
Factors Associated

OBJECTIVE: To assess the prevalence and potential factors associated with pre-pregnancy nutritional status of women. METHODS: This is a cross-sectional study carried out between December 2007 and November 2008 with 1,535 women in the first trimester of pregnancy and randomly selected in health units of the Brazilian public health system (SUS) in the municipalities of Queimados and Petrópolis in the State of Rio de Janeiro. The diagnosis of nutritional deviations was based on the Body Mass Index, according to the classification of the Institute of Medicine, and the following categories were obtained: underweight, normal weight, overweight and obesity. In the statistical analysis, the multinomial logistic regression model was used and an odds ratio and confidence interval of 95% were estimated. RESULTS: The sample included women between 13 and 45 years. The prevalence of underweight, overweight and obesity were 10, 18 and 11%, respectively. Women living in Queimados, adolescents, women who did not live with a partner and smokers had a higher proportion of low pre-pregnancy weight. There was an association between hypertension, overweight and obesity. Adolescents presented lower chance to overweight and obesity. Living in Queimados reduced the odds of overweight. CONCLUSION: The proportion of pre-pregnancy nutritional deviations was high, and recognizing factors that lead to them is very important for an early identification of women at nutritional risk, with view to interventions to reduce the adverse effects of malnutrition on maternal and child health.

scholarly journals Renal function at hospital admission as a prognostic factor in adult hemolytic uremic syndrome. The Italian Registry of Haemolytic Uremic Syndrome.

1992 ◽  
Vol 2 (11) ◽  
pp. 1640-1644 ◽  
Author(s):  
A Schieppati ◽  
P Ruggenenti ◽  
R P Cornejo ◽  
F Ferrario ◽  
G Gregorini ◽  
...  
Keyword(s):  
Renal Function ◽  
Hemolytic Uremic Syndrome ◽  
Acute Phase ◽  
Renal Involvement ◽  
Laboratory Data ◽  
Elevated Serum ◽  
Long Term Outcome ◽  
Uremic Syndrome ◽  
Clinical Records

The clinical records of adult patients with a diagnosis of hemolytic uremic syndrome were retrospectively reviewed with the aim of evaluating the long-term outcome of renal function. The setting is the Italian Registry of Haemolytic Uraemic Syndrome, with which 13 Nephrology Centers have participated. Clinical and laboratory data of 43 patients with hemolytic uremic syndrome were evaluated. The mean age at onset was 34.3 +/- 18.3 yr. Men and women were equally affected. No seasonal trend in presentation was observed. In 20 patients, hemolytic uremic syndrome was primitive, whereas in 23, it was associated with another disease (cancer, preeclampsia, malignant hypertension, vasculitides). Gastrointestinal symptoms were the most frequently observed prodromes. Thirty (70%) patients required dialysis during the acute phase of the disease. Six patients died during the acute phase of the disease, and one died later after discharge (overall mortality, 16%). After 1 yr of follow-up, 11 (26%) patients had recovered a normal renal function, 14 (33%) had hypertension and/or renal insufficiency, and 11 (26%) were on regular dialysis. When prognostic factors of survival and recovery of renal function were considered, it was found that older age was associated with higher mortality in the acute phase, whereas severe renal involvement at the onset of the disease (as expressed by elevated serum creatinine) was associated with a long-term unfavorable prognosis.

scholarly journals Risk Factors Associated with Statin-Associated Muscle Symptoms in Patients Attending a Specialized Regional Lipid Clinic

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
M. K. Saeed ◽  
J. Shah ◽  
R. Damani ◽  
F. Rahman ◽  
P. Patel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Statistical Significance ◽  
University Hospitals ◽  
Antihypertensive Medications ◽  
Factors Associated ◽  
Binomial Logistic Regression ◽  
Lipid Clinic ◽  
The Uk ◽  
Clinical Records

Background. Statin-associated muscle symptoms (SAMS) are the major side effects reported for statins. Data from previous studies suggest that 7–29% of patients on statin had associated muscle symptoms. In the UK, there is a lack of corresponding data on SAMS and factors associated with the development of SAMS. Objective. This analysis is aimed at establishing the prevalence of SAMS and identifying major contributory risk factors in patients attending a lipid clinic. Methods. Clinical records of 535 consecutive patients, who visited the lipid clinic in the University Hospitals of Leicester, were studied retrospectively between 2009 and 2012. SAMS were defined by the presence of muscle symptoms with two or more different statins. Patients who reported muscle symptoms to statin with one or no rechallenge were excluded. The association of SAMS with clinical characteristics such as age and BMI, sex, smoking, excess alcohol, comorbidities, and medications was tested for statistical significance. A binomial logistic regression model was applied to adjust for risk factors significantly associated with SAMS. Results. The prevalence of SAMS was found to be 11%. On unadjusted analysis, the mean age of patients who had SAMS was significantly higher than those without SAMS ( 59.4 ± 10.5 years vs. 50.3 ± 13.4 years, respectively, P < 0.001 ). Nonsmokers were more likely to develop SAMS in comparison to active smokers ( P = 0.037 ). Patients taking antihypertensive medications were more likely to develop SAMS ( P = 0.010 ). In binomial logistic regression analysis, only age was positively and significantly associated with SAMS after adjusting for other risk factors ( β = 0.054 , P = 0.001 ). Conclusion. To the best of our knowledge, this study is the largest cohort of patients with SAMS in the United Kingdom. Our data suggest that the prevalence of SAMS is 11% and increased age is a risk factor associated with the development of SAMS in our cohort of patients.

Spatiotemporal variation of dry spells in the State of Rio de Janeiro: geospatialization and multivariate analysis

2021 ◽  
pp. 105612
Author(s):  
Bruno César Chaves de Oliveira ◽  
José Francisco de Oliveira-Júnior ◽  
Carlos Rodrigues Pereira ◽  
Bruno Serafini Sobral ◽  
Givanildo de Gois ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Rio De Janeiro ◽  
Spatiotemporal Variation ◽  
The State ◽  
Dry Spells

scholarly journals Use of fleuriet model for forecasting and evaluating municipal electoral results in a brazilian state

2020 ◽  
Vol 6 ◽  
Author(s):  
Edson Vinicius Pontes Bastos
Keyword(s):  
Logistic Regression ◽  
Maximum Likelihood ◽  
Rio De Janeiro ◽  
The State ◽  
Financial Information ◽  
Financial Situation ◽  
Dummy Variable ◽  
A Value ◽  
The Relationship ◽  
The City

Objective: Verify the relation between the variables in the Fleuriet model and the electoral result given by the exchange or maintenance of the party of the prefectures under analysis. Methodology: Through logistic regression it is possible to explain or predict the probability of the occurrence of the event under analysis, such event discussed here refers to the exchange of the party, which is a dummy variable that assumes a value of 1 when there is an exchange and zero otherwise, the method of estimation used to obtain the coefficients was based on maximum likelihood. Results: The relationship between the variables of the Fleuriet model and the electoral result given by the exchange or maintenance of the party in the prefectures of the group under analysis. Limitation or implication of the research: It is noteworthy that such research does not allow generalizations, being a study with reduced scope considering only the city halls of the State of Rio de Janeiro that have financial information disclosed. Originality: showing that city halls with better financial situation tend not to change the party, which was observed in the group under analysis considering the election event in 2020.

Shape related features of intracranial aneurysm are associated with rupture status in a large Chinese cohort

2021 ◽  
pp. neurintsurg-2021-017452
Author(s):  
Yuting Wang ◽  
Meixiong Cheng ◽  
Sijie Liu ◽  
Guanglan Xie ◽  
Ling Liu ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Multivariate Analysis ◽  
Intracranial Aneurysms ◽  
Internal Carotid ◽  
Mixed Effect ◽  
Factors Associated ◽  
Ruptured Aneurysms ◽  
Maximal Diameter ◽  
Chinese Cohort ◽  
Male Sex

BackgroundTo investigate the prevalence of small ruptured saccular intracranial aneurysms (sIA) in a Chinese cohort and to identify factors associated with rupture status of sIAs.MethodsConsecutive patients with confirmed sIAs by DSA from January 2015 to July 2019 were included. Demographic and aneurysmal features, including maximal diameter, location, irregularity (lobulated or with blebs), and aspect ratio (AR, defined as height divided by neck width) were recorded and analyzed. Mixed effect logistic regression was used in multivariate analysis.ResultsWe analyzed 1514 sIAs in a Chinese cohort of 1216 patients, including 651 ruptured and 863 unruptured sIAs. Median aneurysm size was 5.7 mm for ruptured aneurysms, with 66.1% <7 mm in maximal diameter, and 40.2% measuring <5 mm. The median PHASES score of ruptured sIAs was 5. In multivariate analysis, male sex, hypertension, locations other than the internal carotid artery, irregularity (lobulated or with blebs), and higher AR were independently associated with rupture status (OR for irregularity, 2.88, 95% CI 2.20 to 3.77, p<0.001; OR for AR, 1.12, 95% CI 1.01 to 1.24, p=0.036). However, maximal diameter was not significantly associated with rupture status (p=0.72).ConclusionsIn this cohort, ruptured sIAs were frequently smaller than 7 mm. Shape related features, such as irregularity and higher AR, were associated with the ruptured status of sIAs, irrespective of diameter. PHASES seems to be inadequate in sIA risk stratification. Shape related parameters may be further investigated in prospective studies.

scholarly journals Self-rated health and substance use among individuals in HIV care in Rio de Janeiro, Brazil: a cross-sectional study

2017 ◽  
Vol 28 (12) ◽  
pp. 1175-1183 ◽  
Author(s):  
Iona K Machado ◽  
Paula M Luz ◽  
Jordan E Lake ◽  
Rodolfo Castro ◽  
Luciane Velasque ◽  
...  
Keyword(s):  
Substance Use ◽  
Logistic Regression ◽  
Rio De Janeiro ◽  
Crack Cocaine ◽  
Morbidity And Mortality ◽  
Hiv Care ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Factors Associated ◽  
Self Rated Health

Self-rated health (SRH) is associated with morbidity and mortality in HIV-uninfected populations but is understudied in HIV. Substance use may affect SRH in addition to its deleterious effect on HIV disease. This analysis aimed to estimate SRH and substance use prevalence and evaluate factors associated with poor SRH among individuals in HIV care in Rio de Janeiro, Brazil. A convenience sample of HIV-infected adults completed one item of SRH, the Alcohol, Smoking and Substance Involvement Screening Test, and the Patient Health Questionnaire-2 (PHQ-2). Logistic regression models identified factors associated with poor SRH. Participants’ (n = 1029) median age was 42.9 years, 64.2% were male, and 54.5% were nonwhite. Poor SRH was reported by 19.5% and the use of alcohol, tobacco, marijuana, and crack/cocaine by 30.1, 19.5, 3.9, and 3.5%, respectively. Less than high school education (adjusted odds ratio [aOR] 1.54, 95% confidence interval [CI]: 1.08–2.20), lack of sexual activity in previous 12 months (aOR 1.53, 95% CI: 1.01–2.30), crack/cocaine use (aOR 3.82, 95% CI: 1.80–8.09), positive PHQ-2 screen (aOR 3.43, 95% CI: 2.09–5.62), and HIV-1 RNA ≥40 c/ml (aOR 2.51, 95% CI: 1.57–4.02) were significantly associated with poor SRH as identified by logistic regression analyses. Alcohol, marijuana, and sedative use were not significantly associated with poor SRH. These results emphasize the need for substance use and mental health screening and treatment in this population. Further research may elucidate the consequences of poor SRH on treatment adherence, morbidity, and mortality in HIV-infected individuals.

scholarly journals Predicting gastrointestinal and renal involvement in adult IgA vasculitis

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Alojzija Hočevar ◽  
Matija Tomšič ◽  
Vesna Jurčić ◽  
Katja Perdan Pirkmajer ◽  
Žiga Rotar
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Multiple Logistic Regression Analysis ◽  
Renal Involvement ◽  
Elevated Serum ◽  
Multivariate Logistic Regression Analysis ◽  
Factors Associated ◽  
Serum Iga ◽  
Pre Treatment

Abstract Background Immunoglobulin A vasculitis (IgAV) is still poorly defined in the adult population. We aimed to determine the predictors of gastrointestinal (GI) or renal involvement in adult IgAV. Methods The prospective study included histologically proven adult IgAV cases diagnosed between January 2013 and July 2019 at our secondary/tertiary rheumatology center. We evaluated the role of clinical and the laboratory parameters as markers predicting the GI or renal involvement in IgAV, using the multiple logistic regression analysis. Results During the 79-month observation period, we identified 214 new adult IgAV cases (59.3% males, median (interquartile range) age 64.6 (57.2–76.7) years). The GI tract and renal involvement developed in 58 (27.1%) and 83 (38.8%) cases, respectively (concurrently in 26 (12.1%) cases). In the multivariate logistic regression analysis, generalized purpura (OR 6.74 (95%CI 3.18–14.31)), the pre-treatment neutrophil to lymphocyte ratio (NLR) > 3.5 (OR 2.78 (95%CI 1.34–5.75)), and elevated serum IgA levels (OR 0.40 (95%CI 0.20–0.79)) were extracted as factors associated with GI complications, whereas current smoking (OR 3.23 (95%CI 1.50–6.98)), generalized purpura (OR 1.98 (95%CI 1.08–3.61)), elevated serum IgA (OR 2.25 (95%CI 1.21–4.18)), NLR > 3.5 (OR 1.96 (95%CI 1.02–3.77)), and marginally age (1.02 (95%CI 1.01–1.04)) emerged as factors associated with renal complications. Conclusion Generalized purpura and pre-treatment NLR predicted both GI and renal involvement, whereas active smoking was associated with renal involvement, and the serum IgA level had a divergent effect on renal and GI involvement in adult IgAV.

scholarly journals Amblyomma cajennense infestation on horses in two microregions of the state of Rio de Janeiro, Brazil

2013 ◽  
Vol 22 (2) ◽  
pp. 235-242 ◽  
Author(s):  
Marcus Sandes Pires ◽  
Tiago Marques dos Santos ◽  
Huarrisson Azevedo Santos ◽  
Joice Aparecida Rezende Vilela ◽  
Maristela Peckle Peixoto ◽  
...  
Keyword(s):  
Rio De Janeiro ◽  
Tick Infestation ◽  
The State ◽  
Infestation Level ◽  
Therapeutic Approaches ◽  
Amblyomma Cajennense ◽  
Factors Associated ◽  
Inappropriate Use ◽  
Low Altitude

The objective of this study was to evaluate factors associated with infestation by Amblyomma cajennense on horses in two microregions of the state of Rio de Janeiro. Horses on 62 farms in the municipalities of the Itaguaí and Serrana microregions were evaluated between January and May 2009. The animals were examined to determine the presence of ticks and infestation level. The animals' rearing and management were assessed on each farm property using an epidemiological questionnaire. Out of the 635 horses evaluated, 41.6% were infested with A. cajennense. It was observed that farms in low-altitude regions (OR=3.69; CI: 2.3-5.8), with unsatisfactory zootechnical and sanitary management (OR=5.92; CI: 3.8-9.2) and an extensive rearing system (OR=4.25; CI: 2.1-8.5) were factors associated with tick infestation (p < 0.05) and also with cases of high infestation on horses. Use of chemical acaricides on horses was also associated with infestation (p < 0.05); the owners described different therapeutic approaches with different treatment intervals. From the present study, low altitudes, unsatisfactory management, extensive rearing and inappropriate use of acaricide products were factors associated with occurrences of A. cajennense at different infestation levels on horses in these municipalities.

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