Some Determinants of the Oslo Breakthrough

1997 ◽  
Vol 2 (2) ◽  
pp. 183-194 ◽  
Author(s):  

AbstractThe breakthrough character of the Oslo agreement is attributed to the mutual recognition between the State of Israel and the PLO and the opening of direct negotiations between them. The parties were induced to go to Oslo and negotiate an agreement there by macro-level forces evolving over some time: Long-term changes, going back to the 1967 War, and short-term strategic and domestic-political considerations, resulting from the Gulf War and the end of the Cold War, created new interests that persuaded them of the necessity of negotiating a compromise; and unofficial interactions between the two sides over the course of two decades persuaded them of the possibility of doing so. Once the parties decided to negotiate, the micro-process provided by Oslo, with its peculiar mixture of track-one and track-two elements, contributed to the success of the negotiations. Key elements included secrecy, the setting, the status of the initial participants, the nature of the third party, and the nature of the mediation process. Finally, what made the accord viable were some of its main substantive features, including the exchange of letters of mutual recognition, the distinction between the interim and the final stage, and the territorial base and early empowerment of the Palestinian Authority.

2021 ◽  
pp. 089020702110173
Author(s):  
Nadin Beckmann ◽  
Damian P Birney ◽  
Amirali Minbashian ◽  
Jens F Beckmann

The study aimed to investigate the status of within-person state variability in neuroticism and conscientiousness as individual differences constructs by exploring their (a) temporal stability, (b) cross-context consistency, (c) empirical links to selected antecedents, and (d) empirical links to longer term trait variability. Employing a sample of professionals ( N = 346) from Australian organisations, personality state data together with situation appraisals were collected using experience sampling methodology in field and repeatedly in lab-like settings. Data on personality traits, cognitive ability, and motivational mindsets were collected at baseline and after two years. Contingent (situation contingencies) and non-contingent (relative SD) state variability indices were relatively stable over time and across contexts. Only a small number of predictive effects of state variability were observed, and these differed across contexts. Cognitive ability appeared to be associated with state variability under lab-like conditions. There was limited evidence of links between short-term state and long-term trait variability, except for a small effect for neuroticism. Some evidence of positive manifold was found for non-contingent variability. Systematic efforts are required to further elucidate the complex pattern of results regarding the antecedents, correlates and outcomes of individual differences in state variability.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Takahiro Kinoshita ◽  
Kensuke Moriwaki ◽  
Nao Hanaki ◽  
Tetsuhisa Kitamura ◽  
Kazuma Yamakawa ◽  
...  

Abstract Background Hybrid emergency room (ER) systems, consisting of an angiography-computed tomography (CT) machine in a trauma resuscitation room, are reported to be effective for reducing death from exsanguination in trauma patients. We aimed to investigate the cost-effectiveness of a hybrid ER system in severe trauma patients without severe traumatic brain injury (TBI). Methods We conducted a cost-utility analysis comparing the hybrid ER system to the conventional ER system from the perspective of the third-party healthcare payer in Japan. A short-term decision tree and a long-term Markov model using a lifetime time horizon were constructed to estimate quality-adjusted life years (QALYs) and associated lifetime healthcare costs. Short-term mortality and healthcare costs were derived from medical records and claims data in a tertiary care hospital with a hybrid ER. Long-term mortality and utilities were extrapolated from the literature. The willingness-to-pay threshold was set at $47,619 per QALY gained and the discount rate was 2%. Deterministic and probabilistic sensitivity analyses were conducted. Results The hybrid ER system was associated with a gain of 1.03 QALYs and an increment of $33,591 lifetime costs compared to the conventional ER system, resulting in an ICER of $32,522 per QALY gained. The ICER was lower than the willingness-to-pay threshold if the odds ratio of 28-day mortality was < 0.66. Probabilistic sensitivity analysis indicated that the hybrid ER system was cost-effective with a 79.3% probability. Conclusion The present study suggested that the hybrid ER system is a likely cost-effective strategy for treating severe trauma patients without severe TBI.


Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 830
Author(s):  
Temple Grandin

In the U.S., the most severe animal welfare problems caused by COViD-19 were in the pork industry. Thousands of pigs had to be destroyed on the farm due to reduced slaughter capacity caused by ill workers. In the future, both short-term and long-term remedies will be needed. In the short-term, a portable electrocution unit that uses scientifically validated electrical parameters for inducing instantaneous unconsciousness, would be preferable to some of the poor killing methods. A second alternative would be converting the slaughter houses to carcass production. This would require fewer people to process the same number of pigs. The pandemic revealed the fragility of large centralized supply chains. A more distributed supply chain with smaller abattoirs would be more robust and less prone to disruption, but the cost of pork would be greater. Small abattoirs can coexist with large slaughter facilities if they process pigs for specialized premium markets such as high welfare pork. The pandemic also had a detrimental effect on animal welfare inspection and third party auditing programs run by large meat buyers. Most in-person audits in the slaughter plants were cancelled and audits were done by video. Video audits should never completely replace in-person audits.


1997 ◽  
Vol 66 (2-3) ◽  
pp. 273-300 ◽  
Author(s):  

AbstractThis article aims to throw a light on the problems relating to the proposed enlargement of the composition of the UN Security Council at present by studying the creation of four non-permanent seats in the Security Council in 1963 from the British and the French perspectives. The examination is based on the author's research of original documents in the archives of the British and French foreign ministries and upon information provided to the author by British, French and Finnish diplomats. The author concludes that, as between 1946 and 1963, British and French short term interests are still best served by maintaining the status quo in the Security Council. However, in a long term perspective it is not clear where the interests of these two States lie.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0247272
Author(s):  
Claudius Gros ◽  
Roser Valenti ◽  
Lukas Schneider ◽  
Benedikt Gutsche ◽  
Dimitrije Marković

The distinct ways the COVID-19 pandemic has been unfolding in different countries and regions suggest that local societal and governmental structures play an important role not only for the baseline infection rate, but also for short and long-term reactions to the outbreak. We propose to investigate the question of how societies as a whole, and governments in particular, modulate the dynamics of a novel epidemic using a generalization of the SIR model, the reactive SIR (short-term and long-term reaction) model. We posit that containment measures are equivalent to a feedback between the status of the outbreak and the reproduction factor. Short-term reaction to an outbreak corresponds in this framework to the reaction of governments and individuals to daily cases and fatalities. The reaction to the cumulative number of cases or deaths, and not to daily numbers, is captured in contrast by long-term reaction. We present the exact phase space solution of the controlled SIR model and use it to quantify containment policies for a large number of countries in terms of short and long-term control parameters. We find increased contributions of long-term control for countries and regions in which the outbreak was suppressed substantially together with a strong correlation between the strength of societal and governmental policies and the time needed to contain COVID-19 outbreaks. Furthermore, for numerous countries and regions we identified a predictive relation between the number of fatalities within a fixed period before and after the peak of daily fatality counts, which allows to gauge the cumulative medical load of COVID-19 outbreaks that should be expected after the peak. These results suggest that the proposed model is applicable not only for understanding the outbreak dynamics, but also for predicting future cases and fatalities once the effectiveness of outbreak suppression policies is established with sufficient certainty. Finally, we provide a web app (https://itp.uni-frankfurt.de/covid-19/) with tools for visualising the phase space representation of real-world COVID-19 data and for exporting the preprocessed data for further analysis.


2012 ◽  
Vol 8 (2) ◽  
pp. 34-38
Author(s):  
Mark T. Kozlowski

The 2012 primary season has been one of the most volatile in recent memory, with the Republican Party struggling to settle on a candidate. The campaign has also vaulted some previously obscure politicians to national prominence, only to relegate them again to obscurity. Ron Paul has demonstrated perhaps the most dramatic transformation, from a lone voice who was once largely ignored to one of the last four candidates for the nomination, who has performed quite creditably in several primaries. In this article, I examine how much influence Paul is going to have in the short term, up to and including the Republican National Convention. I also examine how lasting his influence will be over the long term, and whether or not he will mount a third-party bid in 2012.


2019 ◽  
pp. 138-180
Author(s):  
Douglas Allen

Ever since 9/11 in the US and 26/11 in India, terrorism has been a central concern. Gandhi is generally assumed to be of little value when confronting terrorism today. At best, he is irrelevant; at worst, he is complicit and contributes to the crisis since he opposes necessary violent responses. This essay argues that while Gandhi does not have all of the answers for dealing with terrorism today, he provides us with a complex analysis essential for understanding and responding to the multidimensional structural crisis. After analyzing the nature and meaning of terrorism, we focus on the following topics: Gandhi’s interactions with terrorists; his means-ends analysis and his short-term and long-term preventative approaches to terrorism; his analysis of absolute truth and relative truth in approaching terrorism; and his general analysis of the status of “the other” in transforming our relations with violent, terrorizing, and terrorized others.


2020 ◽  
pp. 1329878X2096156
Author(s):  
Mathias-Felipe de-Lima-Santos ◽  
Aljosha Karim Schapals ◽  
Axel Bruns

The proliferation of data journalism has enabled newsrooms to deploy technologies for both mundane and more sophisticated workplace tasks. To bypass long-term investment in developing data skills, out-of-the-box software solutions are commonly used. Newsrooms today are partially dependent on third-party platforms to build interactive and visual stories – but the business models of platforms are predisposed to changes, frequently inducing losses of stories. This article combines in-depth interviews and an ancillary survey to study the status quo and identify future challenges in embracing out-of-the-box and in-house tools, and their impact on Australian data journalism. Results indicate a dichotomy between commercial and public service media organisations. Commercial outlets are heavily reliant on out-of-the-box solutions to develop stories, due to a lack of skillsets and a shortage of skilled labour. By contrast, public service media are developing their own in-house solutions, which reflects their desire for the continuous digital preservation of data stories despite the challenges identified.


2016 ◽  
Vol 13 (1) ◽  
Author(s):  
Dana P. Goldman ◽  
Darius N. Lakdawalla ◽  
James R. Baumgardner ◽  
Mark T. Linthicum

AbstractMedical innovation has generated significant gains in health over the past decades, but these advances have been accompanied by rapid growth in healthcare spending. Faced with a growing number of high-cost but high-impact innovations, some have argued to constrain prices for new therapies – especially through global caps on pharmaceutical spending and limits on prices for individual drugs. We show that applying this threshold to past innovations would have limited access to many highly valuable drugs such as statins and anti-retrovirals. We also argue that budget caps violate several important principles of health policy. First, budget caps treat healthcare spending as a consumption good, like going to a movie or buying a meal. However, healthcare spending should be viewed as an investment, whose benefits accrue over many years – much like spending on education. Second, budgetary cost is a poor indicator of value, thereby distorting coverage decisions. Third, affordability arguments often use a short-term horizon, thereby missing that long-term health is society’s ultimate goal. Fourth, assessments of benefit should incorporate not just the immediate clinical benefit to patients, but also long-term health improvements, cost savings, and increased productivity. Fifth, global budget caps arbitrarily anchor spending on the status quo, thereby setting too stringent a threshold for socially-desirable innovation. In sum, a solitary focus on short-term costs can be detrimental to population health in the long-run. When medical treatment decisions are properly viewed as investments, budget caps are not the answer; rather, we need to find mechanisms to encourage spending decisions based on long-term value. Only then can we generate health returns to societal investments, while also encouraging the new research and development necessary to extend the gains of recent decades.


Antioxidants ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 537
Author(s):  
Silke B. Lohan ◽  
Karl Bühring ◽  
Anna-Christina Lauer ◽  
Annette Friedrich ◽  
Jürgen Lademann ◽  
...  

The daily consumption of tobacco products leads to a boost in free radical production in tissues, promoting the risk for malignancies, metabolic alterations and chronic-inflammatory diseases. This study aimed to broaden the knowledge of the status of the antioxidative (AO) system in the skin, compared to the blood, of healthy appearing smokers. Both, the basic status compared to non-smokers and the short-term impact of controlled cigarette consumption in smokers were analyzed. Our study showed that the basic level of the AO system of smokers significantly differed from that of non-smokers. As determined by resonant Raman spectroscopy (RRS), the levels of exogenous AOs were decreased in both, the skin, in vivo (β-carotene and lycopene), and blood plasma (β-carotene only). In contrast, the levels of glutathione (GSH), the prototypical endogenous AO, which were analyzed by fluorimetric assays in cutaneous tape strips and blood plasma, were increased in the skin, although unchanged in the blood of smokers. Elevated cutaneous GSH levels were reflected by an elevated overall radical scavenging activity in the skin, as quantified by non-invasive electron paramagnetic resonance (EPR) spectroscopy. Analysis of the expression of selected stress-associated genes in blood immune cells by quantitative RT-PCR in subgroups of non-smokers and smokers additionally demonstrated the downregulation of AKR1C2 in smokers, and its negative correlation with blood plasma levels of the protective immune mediator interleukin-22, assessed by the ELISA technique. Controlled cigarette consumption did not alter exogenous or endogenous AOs in the skin of smokers, but decreased lycopene levels in blood plasma. Moreover, there was a decline in blood IL-22 levels, while no relevant response of blood cell gene expressions was found after the considered short time. Our data therefore demonstrate a strengthened endogenous AO status in the skin of smokers, which may indicate a long-term adaptation to chronic oxidative stress in this specific organ. While this effect was not clearly visible in the blood, this compartment seems to be useful as an immediate indicator of the body’s AO consumption. Moreover, decreased levels of AKR1C2, which we show for the first time to be expressed in immune cells, may be a candidate marker for long-term smoking. In addition, this study demonstrates that the rate constant of a spin probe decline determined by EPR spectroscopy mainly represents the endogenous AO status of a tissue.


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