Potential Vorticity Diagnosis of the Severe Convective Regime. Part IV: Comparison with Modeling Simulations of the Moore Tornado Outbreak

2008 ◽  
Vol 136 (5) ◽  
pp. 1612-1629 ◽  
Author(s):  
David A. Gold ◽  
John W. Nielsen-Gammon
Keyword(s):  
Numerical Simulation ◽  
Conceptual Model ◽  
Case Studies ◽  
Potential Vorticity ◽  
Oklahoma City ◽  
Additional Insight ◽  
Convective Regime ◽  
Diagnostic Framework ◽  
Insight Into ◽  
Tornado Outbreak

Abstract A potential vorticity (PV) diagnostic framework is used to explore the sensitivity of the 3 May 1999 Oklahoma City tornado outbreak to the strength of a particular PV anomaly proximate to the geographical region experiencing the tornado outbreak. The results derived from the balanced PV diagnosis agree broadly with those obtained previously in a numerical simulation of the same event, while offering additional insight into the nature of the sensitivity. Similar to the findings of other cases, the balanced diagnosis demonstrates that intensifying (removing) the PV anomaly of interest increases (decreases) the balanced CAPE over the southwestern portion of the outbreak region, reduces (increases) the storm-relative helicity, and increases (reduces) ascent. The latter finding, coupled with the results of the modeling study, demonstrates that intensifying a PV anomaly proximate to an outbreak environment can increase the likelihood that more widespread and possibly less tornadic convection will ensue. The overall results of the balanced diagnosis complement those of other case studies, leading to the formulation of a conceptual model that broadly anticipates how the convective regime will respond to changes in intensity of upper-tropospheric weather features.

scholarly journals A novel method for objective identification of 3-D potential vorticity anomalies

2022 ◽  
Author(s):  
Christoph Fischer ◽  
Andreas H. Fink ◽  
Elmar Schömer ◽  
Roderick van der Linden ◽  
Michael Maier-Gerber ◽  
...  
Keyword(s):  
Numerical Simulation ◽  
Case Studies ◽  
Potential Vorticity ◽  
Three Dimensional ◽  
Simulation Models ◽  
Atmospheric Dynamics ◽  
Precipitation Event ◽  
Efficient Computation ◽  
Morphological Image Processing

Abstract. Potential vorticity (PV) analysis plays a central role in studying atmospheric dynamics and in particular in studying the life cycle of weather systems. The three-dimensional (3-D) structure and temporal evolution of the associated PV anomalies, however, are not yet fully understood. An automated technique to objectively identify 3-D PV anomalies can help to shed light on 3-D atmospheric dynamics in specific case studies, as well as facilitate statistical evaluations within climatological studies. Such a technique to identify PV anomalies fully in 3-D, however, does not yet exist. This study presents a novel algorithm for the objective identification of PV anomalies in gridded data, as commonly output by numerical simulation models. The algorithm is inspired by morphological image processing techniques and can be applied to both two-dimensional (2-D) and 3-D fields on vertically isentropic levels. The method maps input data to a horizontally stereographic projection and relies on an efficient computation of horizontal distances within the projected field. Candidates for PV anomaly features are filtered according to heuristic criteria, and feature description vectors are obtained for further analysis. The generated feature descriptions are well suited for subsequent case studies of 3-D atmospheric dynamics as represented by the underlying numerical simulation, or for generation of climatologies of feature characteristics. We evaluate our approach by comparison with an existing 2-D technique, and demonstrate the full 3-D perspective by means of a case study of an extreme precipitation event that was dynamically linked to a prominent subtropical PV anomaly. The case study demonstrates variations in the 3-D structure of the detected PV anomalies that would not have been captured by a 2-D method. We discuss further advantages of using a 3-D approach, including elimination of temporal inconsistencies in the detected features due to 3-D structural variation, and elimination of the need to manually select a specific isentropic level on which the anomalies are assumed to be best captured. The method is made available as open-source for straightforward use by the atmospheric community.

Circuit Theory and Analog Electronics — Computer Aided Teaching

1997 ◽  
Vol 34 (2) ◽  
pp. 141-160
Author(s):  
Hemanshu R. Pota
Keyword(s):  
Numerical Simulation ◽  
Circuit Theory ◽  
Symbolic Manipulation ◽  
Additional Insight ◽  
Analog Electronics ◽  
Computer Aided ◽  
Approach To Teaching ◽  
Insight Into ◽  
Simulation Package

A computer aided approach to teaching undergraduate courses in circuit theory and electronics is discussed. It is shown that symbolic manipulation packages like MAPLE give an additional insight into the analysis — complementing the analysis using a numerical simulation package like SPICE — enabling the students to understand complicated circuits.

Classification of Infant Vocalizations by Untrained Listeners

2019 ◽  
Vol 62 (9) ◽  
pp. 3265-3275
Author(s):  
Heather L. Ramsdell-Hudock ◽  
Anne S. Warlaumont ◽  
Lindsey E. Foss ◽  
Candice Perry
Keyword(s):  
Formal Education ◽  
Additional Insight ◽  
Listener Responses ◽  
Infant Vocalization ◽  
Early Infant ◽  
Infant Vocalizations ◽  
Audio Recordings ◽  
Speech And Language Development ◽  
Insight Into

Purpose To better enable communication among researchers, clinicians, and caregivers, we aimed to assess how untrained listeners classify early infant vocalization types in comparison to terms currently used by researchers and clinicians. Method Listeners were caregivers with no prior formal education in speech and language development. A 1st group of listeners reported on clinician/researcher-classified vowel, squeal, growl, raspberry, whisper, laugh, and cry vocalizations obtained from archived video/audio recordings of 10 infants from 4 through 12 months of age. A list of commonly used terms was generated based on listener responses and the standard research terminology. A 2nd group of listeners was presented with the same vocalizations and asked to select terms from the list that they thought best described the sounds. Results Classifications of the vocalizations by listeners largely overlapped with published categorical descriptors and yielded additional insight into alternate terms commonly used. The biggest discrepancies were found for the vowel category. Conclusion Prior research has shown that caregivers are accurate in identifying canonical babbling, a major prelinguistic vocalization milestone occurring at about 6–7 months of age. This indicates that caregivers are also well attuned to even earlier emerging vocalization types. This supports the value of continuing basic and clinical research on the vocal types infants produce in the 1st months of life and on their potential diagnostic utility, and may also help improve communication between speech-language pathologists and families.

Diversity, Rationality, and the Division of Cognitive Labor

2017 ◽  
Author(s):  
Ryan Muldoon
Keyword(s):  
Social Structure ◽  
Division Of Labor ◽  
Additional Insight ◽  
Division Of Cognitive Labor ◽  
Social Structure Of Science ◽  
The Social ◽  
Insight Into

Existing models of the division of cognitive labor in science assume that scientists have a particular problem they want to solve and can choose between different approaches to solving the problem. In this essay I invert the approach, supposing that scientists have fixed skills and seek problems to solve. This allows for a better explanation of increasing rates of cooperation in science, as well as flows of scientists between fields of inquiry. By increasing the realism of the model, we gain additional insight into the social structure of science and gain the ability to ask new questions about the optimal division of labor.

scholarly journals Using syndromic measures of mortality to capture the dynamics of COVID-19 in Java, Indonesia, in the context of vaccination rollout

BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Bimandra A. Djaafara ◽  
Charles Whittaker ◽  
Oliver J. Watson ◽  
Robert Verity ◽  
Nicholas F. Brazeau ◽  
...  
Keyword(s):  
Rural Areas ◽  
Vaccination Campaign ◽  
Control Measures ◽  
Additional Insight ◽  
Short Term ◽  
If Current ◽  
Vaccine Impact ◽  
Potential Impact ◽  
The Impact ◽  
Insight Into

Abstract Background As in many countries, quantifying COVID-19 spread in Indonesia remains challenging due to testing limitations. In Java, non-pharmaceutical interventions (NPIs) were implemented throughout 2020. However, as a vaccination campaign launches, cases and deaths are rising across the island. Methods We used modelling to explore the extent to which data on burials in Jakarta using strict COVID-19 protocols (C19P) provide additional insight into the transmissibility of the disease, epidemic trajectory, and the impact of NPIs. We assess how implementation of NPIs in early 2021 will shape the epidemic during the period of likely vaccine rollout. Results C19P burial data in Jakarta suggest a death toll approximately 3.3 times higher than reported. Transmission estimates using these data suggest earlier, larger, and more sustained impact of NPIs. Measures to reduce sub-national spread, particularly during Ramadan, substantially mitigated spread to more vulnerable rural areas. Given current trajectory, daily cases and deaths are likely to increase in most regions as the vaccine is rolled out. Transmission may peak in early 2021 in Jakarta if current levels of control are maintained. However, relaxation of control measures is likely to lead to a subsequent resurgence in the absence of an effective vaccination campaign. Conclusions Syndromic measures of mortality provide a more complete picture of COVID-19 severity upon which to base decision-making. The high potential impact of the vaccine in Java is attributable to reductions in transmission to date and dependent on these being maintained. Increases in control in the relatively short-term will likely yield large, synergistic increases in vaccine impact.

scholarly journals Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1909
Author(s):  
Joachim T. Siaw ◽  
Jonatan L. Gabre ◽  
Ezgi Uçkun ◽  
Marc Vigny ◽  
Wancun Zhang ◽  
...  
Keyword(s):  
Genome Engineering ◽  
Neuroblastoma Cells ◽  
Gene Signature ◽  
Additional Insight ◽  
Downstream Target ◽  
Anaplastic Lymphoma ◽  
Extracellular Matrix Components ◽  
Transforming Gene ◽  
Insight Into

Aberrant activation of anaplastic lymphoma kinase (ALK) drives neuroblastoma (NB). Previous work identified the RET receptor tyrosine kinase (RTK) as a downstream target of ALK activity in NB models. We show here that ALK activation in response to ALKAL2 ligand results in the rapid phosphorylation of RET in NB cells, providing additional insight into the contribution of RET to the ALK-driven gene signature in NB. To further address the role of RET in NB, RET knockout (KO) SK-N-AS cells were generated by CRISPR/Cas9 genome engineering. Gene expression analysis of RET KO NB cells identified a reprogramming of NB cells to a mesenchymal (MES) phenotype that was characterized by increased migration and upregulation of the AXL and MNNG HOS transforming gene (MET) RTKs, as well as integrins and extracellular matrix components. Strikingly, the upregulation of AXL in the absence of RET reflects the development timeline observed in the neural crest as progenitor cells undergo differentiation during embryonic development. Together, these findings suggest that a MES phenotype is promoted in mesenchymal NB cells in the absence of RET, reflective of a less differentiated developmental status.

Technology in Context: Mediating Factors in the Utilization of Planning Technologies

2005 ◽  
Vol 37 (5) ◽  
pp. 895-907 ◽  
Author(s):  
Ari Goelman
Keyword(s):  
Organizational Structure ◽  
Information Technologies ◽  
Public Access ◽  
Web Gis ◽  
Gis Technology ◽  
Additional Insight ◽  
Mediating Factors ◽  
The Impact ◽  
Insight Into

My research explores the question: how can theorists better understand the ways in which planning technologies are used by municipal planners? In the case-study municipality, a recently introduced web-GIS technology had little demonstrable success in attaining two of its stated goals: enabling increased public access to municipal geographic information and encouraging planners to produce their own maps. My research links these outcomes not only to the technologies themselves, but to organizational structure and human agency. Planners and planning theorists can gain additional insight into the impact of planning technologies through closer attention to the process through which planners come to use information technologies and the way this process both alters and is constrained by existing organizational constraints, including previously adopted technologies.

The impact of tinnitus characteristics and associated variables on tinnitus-related handicap

2015 ◽  
Vol 130 (1) ◽  
pp. 25-31 ◽  
Author(s):  
S Degeest ◽  
P Corthals ◽  
I Dhooge ◽  
H Keppler
Keyword(s):  
Additional Insight ◽  
Tinnitus Handicap Inventory ◽  
Hearing Status ◽  
Questionnaire Score ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship ◽  
Sample Case ◽  
Insight Into ◽  
Associated Variables

AbstractObjective:This study aimed to determine the characteristics of tinnitus and tinnitus-related variables and explore their possible relationship with tinnitus-related handicap.Methods:Eighty-one patients with chronic tinnitus were included. The study protocol measured hearing status, tinnitus pitch, loudness, maskability and loudness discomfort levels. All patients filled in the Tinnitus Sample Case History Questionnaire, the Hyperacusis Questionnaire and the Tinnitus Handicap Inventory. The relationship of each variable with the Tinnitus Handicap Inventory score was evaluated by univariate and multivariate analyses.Results:Five univariables were associated with the Tinnitus Handicap Inventory score: loudness discomfort level, subjective tinnitus loudness, tinnitus awareness, noise intolerance and Hyperacusis Questionnaire score. Multiple regression analysis showed that the Hyperacusis Questionnaire score and tinnitus awareness were independently associated with the Tinnitus Handicap Inventory score.Conclusion:Hyperacusis and tinnitus awareness were independently associated with the Tinnitus Handicap Inventory score. Questionnaires on tinnitus and hyperacusis are especially suited to providing additional insight into tinnitus-related handicap and are therefore useful for evaluating tinnitus patients.

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