Traditionally, international relations (IR) conceptualized technology primarily as a static, neutral, and passive tool, which emanates from impenetrable black boxes outside the international system. According to this predominant instrumental understanding of technology, IR “added” technology as a residual variable to existing explanatory frameworks. Consequently, qualitative systemic change—as well as continuity—could only be addressed within existing models and their respective core variables. Subsequently, traditional approaches increasingly experienced difficulties to adequately capture and explain empirically observable systemic changes in the form of growing interdependence, globalization, or trans-nationalization, as well as a plethora of technology-induced new policy challenges. Contrary to traditional conceptualizations, a growing number of scholars have instead embarked on a project to open the “black box” by redefining technology as a highly political and integral core component of global affairs that shapes and itself is shaped by global economics, politics, and culture. A rapidly growing body of theoretically diverse interdisciplinary literature systematically incorporates insights from science and technology studies (STS) to provide a more nuanced understanding of how technology, the global system, and its myriad actors mutually constitute and impact one another.