Videoesophagography versus Endoscopy for Prediction of Intraoperative Hiatal Hernia Size

2018 ◽  
Vol 84 (3) ◽  
pp. 387-391 ◽  
Author(s):  
James M. Tatum ◽  
Kamran Samakar ◽  
Michael E. Bowdish ◽  
Wendy J. Mack ◽  
Nikolai Bildzukewicz ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Cohort Study ◽  
Laparoscopic Surgery ◽  
Hiatal Hernia ◽  
Retrospective Cohort ◽  
Linear Regression Analysis ◽  
Preoperative Assessment ◽  
Magnetic Sphincter Augmentation ◽  
Operative Assessment ◽  
Hernia Size

Magnetic sphincter augmentation is a novel surgical procedure for gastroesophageal reflux disease. Limited dissection at the hiatus is one of the benefits of the procedure, but makes precise and accurate preoperative assessment of even small hiatal hernia critical. Retrospective cohort study of 136 patients having undergone both endoscopy (EGD) and videoesophagography followed by operative assessment for hiatal hernia during magnetic sphincter augmentation. The objective of the study is to determine which preoperative modality more accurately predicts operative hiatal hernia size. Videoesophagography underestimated operative measurement by 0.37 ± 1.41 cm ( P = 0.003) and was less accurate in predicting intraoperative hiatal hernia size than EGD on linear regression analysis (β -0.729, SE 0.057, P < 0.001). EGD was less accurate at predicting hiatal hernia size as patient age increased (β -0.018, SE 0.007, P = 0.014) and with larger hernias (β -0.615, standard error (SE) 0.067, P < 0.001); however, endoscopic measurements did not differ significantly from intraoperative measurements (0.93 ± 1.23 cm vs 1.12 ± 1.43 cm, P = 0.12). EGD better predicts the size of small hiatal hernia measured during subsequent laparoscopic surgery.

Hyperkalemia of the blood-primed ECLS circuit does not result in post-initiation hyperkalemia in infants < 10 kg

Perfusion ◽  
2006 ◽  
Vol 21 (3) ◽  
pp. 173-177 ◽  
Author(s):  
Geoffrey M Fleming ◽  
Robert T Remenapp ◽  
Robert H Bartlett ◽  
Gail M Annich
Keyword(s):  
Regression Analysis ◽  
Cohort Study ◽  
Linear Regression ◽  
Retrospective Cohort ◽  
Potassium Level ◽  
Pediatric Patients ◽  
Life Support ◽  
Extracorporeal Life Support ◽  
Linear Regression Analysis ◽  
Multivariate Linear Regression Analysis

Objective: To assess the risk of hyperkalemia with blood-primed extracorporeal life support (ECLS) circuits in infants < 10 kg. Design: Retrospective cohort study of all neonatal and pediatric patients <10 kg placed on ECLS from May 1998 to April 2001. Measurements and main results: Data collection including patient weight, patient potassium levels pre- and post-initiation of ECLS, potassium level of the primed ECLS circuit, age of the packed red blood cell (PRBC) unit, type of preservative, and preservative reduction status. Seventy-six circuits were available for the analysis. The age of the PRBC unit and preservative reduction status significantly affected the potassium level of the primed ECLS circuit. Multivariate linear regression analysis showed no significant effect on the post-ECLS initiation patient potassium level with respect to the PRBC age, the preservative reduction status, the patient potassium level prior to ECLS initiation, and the potassium level of the primed ECLS circuit. Conclusions: Initiation of ECLS in infants <10 kg should not be delayed unnecessarily to perform preservative reduction or to utilize PRBC units of a specific age, as hyperkalemia of the primed ECLS circuit is not associated with systemic hyperkalemia in the patient post-initiation of ECLS.

scholarly journals Concentric and eccentric isokinetic hamstring injury risk among 582 professional elite soccer players: a 10-years retrospective cohort study

2020 ◽  
Vol 6 (1) ◽  
pp. e000868
Author(s):  
Ricardo Lima Burigo ◽  
Robson Dias Scoz ◽  
Bruno Mazziotti de Oliveira Alves ◽  
Rubens Alexandre da Silva ◽  
Cesar Augusto Melo-Silva ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Injury Risk ◽  
Peak Torque ◽  
Soccer Players ◽  
Complex Data ◽  
Isokinetic Test ◽  
Clinical Records

Background/AimDifferent authors have tried to correlate the peak isokinetic torque values with the incidence of soccer match injuries. However, due to the wide variety of assessment testing protocols, such an inference becomes difficult. This study aimed to verify the capacity of an isokinetic test to establish injury risk reference values for hamstring strain injuries.MethodsA retrospective cohort study based on isokinetic data and clinical records from the last 10 years was conducted in 582 Brazilian elite-professional soccer players, who were subjected to the same isokinetic test protocol, machine, and tester. A Multivariate Logistic Regression Analysis for Complex Data Sampling was used to generate injury risk statistical indexes.ResultsMultivariate regression analysis of both legs provided important data to identify the cut-off values of Concentric Peak Torque (181.82 Newton/*metres), Concentric Work (236.23 watts) and Concentric Power (130.11 joules).ConclusionsThe injury risk indexes indicate that an increase of just one Newton unit in CPT (Concentric Peak Torque) and CJ (Concentric Power) above those cut-off values, can reduce the risk of future injuries by 2% and 2.7%, respectively.

scholarly journals Being Praised for Prosocial Behaviors Longitudinally Reduces Depressive Symptoms in Early Adolescents: a Population-based Cohort Study

2021 ◽  
Author(s):  
Daiki Nagaoka ◽  
Nanami Tomoshige ◽  
Shuntaro Ando ◽  
Masaya Morita ◽  
Tomoki Kiyono ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Cohort Study ◽  
Depressive Symptoms ◽  
Prosocial Behavior ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Population Based ◽  
Self Report ◽  
Partial Regression ◽  
Heavy Burden

Abstract Background: Depression is highly prevalent and causes a heavy burden in adolescent life. Being praised for prosocial behavior might be a preventive factor because both being praised and prosocial behavior are protective against depression. Here, we investigated the longitudinal relationship between being praised for prosocial behavior and depressive symptoms in adolescents. Methods: In Tokyo Teen Cohort study (TTC), an ongoing prospective population-based cohort study, we collected 3,171 adolescents’ data on self-reported experiences of being praised for prosocial behavior, depressive symptoms, and caregiver-evaluated prosocial behavior. Ten-year-old children were asked to freely describe answers to the question “What are you praised for?”. Only children who clearly answered that they were praised for their prosocial behavior were designated the “prosocial praise group”. The degree of depression at ages 10 and 12 was measured with the Short Mood and Feelings Questionnaire (SMFQ), a self-report questionnaire about depression. Objective prosocial behavior of the 10-year-old children was assessed by the Strength and Difficulty Questionnaire (SDQ). Multiple linear regression analysis was performed using the SMFQ score at age 12 as the objective variable and being praised for prosocial behavior as the main explanatory variable, and the SMFQ score at age 10 and the objective prosocial behavior at age 10 were included as confounders.Results: Depressive symptoms (SMFQ scores) in the “prosocial praise group” were significantly lower than those in the other group both at age 10 (4.3 ± 4.4 vs 4.9 ± 4.6, p <0.001) and at age (3.4 ± 4.2 vs 4.0 ± 4.6, p <0.01). In the single regression analysis, the children who reported being praised for prosocial behavior at age 10 had significantly lower depressive symptoms at age 12 (partial regression variable: -0.57, 95% confidence interval (CI) [-0.96, -0.17]). This association remained significant after adjusting for confounders, including baseline depressive symptoms (partial regression variable: -0.44, 95% CI [-0.80, -0.08]). Prosocial behavior alone was not associated with depressive symptoms. Conclusions: Being praised for prosocial behavior rather than objective prosocial behavior at 10 years of age predicted lower depressive symptoms two years later. Praise for adolescents’ prosocial behavior can be encouraged to prevent depression.

scholarly journals Development of a preoperative index-based nomogram for the prediction of hypokalemia in patients with pituitary adenoma: a retrospective cohort study

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11650
Author(s):  
Wenpeng Li ◽  
Lexiang Zeng ◽  
Deping Han ◽  
Shanyi Zhang ◽  
Bingxi Lei ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Cohort Study ◽  
Pituitary Adenoma ◽  
Logistic Regression Analysis ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Close Monitoring ◽  
Training Set ◽  
Nonlinear Association

Objective To develop and validate a preoperative index-based nomogram for the prediction of hypokalemia in patients with pituitary adenoma (PA). Methods This retrospective cohort study included 205 patients with PAs between January 2013 and April 2020 in the Sun Yat-sen Memorial Hospital, Guangzhou, China. The patients were randomly classified into either a training set (N = 143 patients) and a validation set (N = 62 patients) at a ratio of 7:3. Variables, which were identified by using the LASSO regression model were included for the construction of a nomogram, and a logistic regression analysis was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) in the training set. The area under the curve (AUC) was used to evaluate the performance of the nomogram for predicting hypokalemia. Multivariate logistic regression analysis with a restricted cubic spline analysis was conducted to identify a potential nonlinear association between the preoperative index and hypokalemia. Results The incidence of hypokalemia was 38.05%. Seven preoperative indices were identified for the construction of the nomogram: age, type of PA, weight, activated partial thromboplastin time, urea, eosinophil percentage, and plateletocrit. The AUCs of the nomogram for predicting hypokalemia were 0.856 (95% CI [0.796–0.915]) and 0.652 (95% CI [0.514–0.790]) in the training and validation sets, respectively. Restricted cubic splines demonstrated that there was no nonlinear association between hypokalemia and the selected variables. Conclusion In this study, we constructed a preoperative indices-based nomogram that can assess the risk of hypokalemia after the surgical treatment of pituitary adenomas. This nomogram may also help to identify high risk patients who require close monitoring of serum potassium.

scholarly journals The Role of Imaging in the Preoperative Assessment of Patients with Nasal Obstruction and Septal Deviation—A Retrospective Cohort Study

2020 ◽  
Author(s):  
Narin Nard Carmel-Neiderman ◽  
Ahmad Safadi ◽  
Anat Wengier ◽  
Tomer Ziv-Baran ◽  
Anton Warshavsky ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cohort Study ◽  
Nasal Obstruction ◽  
Retrospective Cohort Study ◽  
Nasal Septum ◽  
Retrospective Cohort ◽  
Preoperative Planning ◽  
Preoperative Assessment ◽  
Ct Scans ◽  
Radiological Findings

Abstract Introduction Isolated nasal obstruction (INO) is a common complaint of multiple etiology. The preoperative evaluation of patients presenting with nasal obstruction and deviated nasal septum (DNS) does not typically include imaging. The benefits of performing computed tomography (CT) in the preoperative setting are inconclusive. Objective Assessing the contribution of preoperative CT to the surgical treatment of non-sinusitis patients presenting with INO and DNS. Methods A retrospective cohort study on patients referred to surgery for nasal obstruction due to DNS or turbinate hypertrophy between 2006 and 2015. Data was retrieved from patients' medical charts. The CT scans and clinical data were reassessed by a second surgeon blinded to the patients' clinical course. Results Seventy of the 843 patients (8.06%) who underwent endoscopic sinonasal procedures during the study period had presented with INO and met the inclusion criteria. Thirty-eight (55.88%) of them underwent CT scans during their preoperative assessment. Modification of the initial preoperative planning based on the radiological findings was required in 32 cases (84.2%). When reassessed by a second blinded surgeon, 58% of cases required surgical modification rather than classical submucosal resection of nasal septum and turbinate reduction (P = 0.048). Conclusion Computed tomography was found beneficial in the preoperative planning for patients with INO. The original surgical plan based upon physical examination findings was modified based on radiological findings in 84.2% of the patients.

Adhesion-related readmissions after open and laparoscopic surgery: a retrospective cohort study (SCAR update)

The Lancet ◽  
2020 ◽  
Vol 395 (10217) ◽  
pp. 33-41 ◽  
Author(s):  
Pepijn Krielen ◽  
Martijn W J Stommel ◽  
Pille Pargmae ◽  
Nicole D Bouvy ◽  
Erica A Bakkum ◽  
...  
Keyword(s):  
Cohort Study ◽  
Laparoscopic Surgery ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort

scholarly journals D6 blastocyst transfer on day 6 in frozen-thawed cycles should be avoided: a retrospective cohort study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Huiling Xu ◽  
Shumin Qiu ◽  
Xiaojing Chen ◽  
Suqin Zhu ◽  
Yan Sun ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Cohort Study ◽  
Logistic Regression Analysis ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Hormone Replacement ◽  
Implantation Rate ◽  
Blastocyst Transfer ◽  
Miscarriage Rate

Abstract Background There is no definitive evidence about the suitable timing to transfer blastocysts formed and cryopreserved on day 6 (D6 blastocysts) in frozen-thawed embryo transfer (FET) cycles. This study aimed to investigate the suitable timing to transfer D6 blastocysts in FET cycles and to identify factors affecting clinical pregnancy rate (CPR) and early miscarriage rate (EMR) in FET cycles with blastocysts. Methods This retrospective cohort study included 1788 FET cycles with blastocysts. There were 518 cycles with D6 blastocysts, and 1270 cycles with blastocysts formed and cryopreserved on day 5 (D5 blastocysts) (D5 group). According to the blastocyst transfer timing, the cycles with D6 blastocysts were divided into cycles with D6 blastocysts transferred on day 5 (D6-on-D5 group, 103 cycles) and cycles with D6 blastocysts transferred on day 6 (D6-on-D6 group, 415 cycles). The chi-square test, independent t-test or Mann-Whitney test, and logistic regression analysis were used for data analysis. Results The CPR and implantation rate (IR) were significantly higher in the D6-on-D5 group than in the D6-on-D6 group (55.3% vs. 37.3%, 44.8% vs. 32.6%, P < 0.01). The CPR and IR were significantly higher in the D5 group than in the D6-on-D5 group (66.0% vs. 55.3%, 62.1% vs. 44.8%, P < 0.05), and the EMR was significantly lower in the D5 group than in the D6-on-D5 group (11.2% vs. 21.1%, P < 0.05). Logistic regression analysis demonstrated that transfer D6 blastocysts on day 5, instead of day 6, could significantly increase the CPR (odds ratio[OR]: 2.031, 95% confidence interval (CI): 1.296–3.182, P = 0.002). FET cycles with D6 blastocysts transferred on day 5 had a higher EMR than those with D5 blastocysts (OR: 2.165, 95% CI: 1.040–4.506, P = 0.039). Hormone replacement therapy (HRT) cycles exhibited a higher EMR than natural cycles (OR: 1.953, 95% CI: 1.254–3.043, P = 0.003), while no difference was observed in the CPR (P > 0.05). Conclusions These results indicate that the suitable timing to transfer D6 blastocysts in FET cycles may be day 5, and D6 blastocyst transfer on day 6 in FET cycles should be avoided. D6 blastocysts transfer and HRT cycles may be associated with a higher EMR.

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