Retrospective Investigation of Contralateral Hearing Thresholds of Patients With Sporadic Vestibular Schwannoma

2021 ◽  
pp. 019459982110335
Author(s):  
Nicole Peter ◽  
Alexander Huber ◽  
Simon Egli ◽  
Ulrike Held ◽  
Klaus Steigmiller ◽  
...  
Keyword(s):  
Vestibular Schwannoma ◽  
Normative Values ◽  
High Frequencies ◽  
Hearing Thresholds ◽  
Norm Values ◽  
Before And After ◽  
Male Patients ◽  
The Mean ◽  
Contralateral Ear ◽  
Indirect Indication

Objective The aim of this study was to investigate the contralateral hearing of patients with sporadic vestibular schwannoma (VS). Study Design Retrospective cohort study. Setting Pure-tone audiograms of the contralateral ear from patients with a wait-and-scan strategy were compared to the ones who received therapy. Due to a possible bias caused by the therapy, hearing thresholds before and after radiotherapy or surgery were compared separately with the wait-and-scan group. Methods From 1979 to 2017, 508 patients with sporadic VS could be included in the study. Of these, 240 received regular controls in the sense of wait-and-scan, 72 underwent radiotherapy (63 audiograms before and 43 after radiotherapy), and 196 had a surgery (186 audiograms before and 146 after surgery). Age-normalized hearing thresholds of the contralateral ear from patients with a wait-and-scan strategy were compared to ones who received therapy. In addition, hearing thresholds were compared to norm values. Results There was no evidence for a difference in the contralateral hearing of patients with sporadic VS between the wait-and-scan and therapy groups. The mean difference of hearing thresholds in our sample to norm values was found to be larger for the high frequencies and more pronounced in male patients. Conclusion There was no evidence for a difference in the contralateral hearing loss of patients with sporadic VS between the wait-and-scan and therapy groups. However, there was some indirect indication of poorer contralateral hearing in all patients with sporadic VS compared to normative values.

scholarly journals Variation in the Hearing Threshold in Women during the Menstrual Cycle

2017 ◽  
Vol 21 (04) ◽  
pp. 323-328 ◽  
Author(s):  
Dayse Souza ◽  
Brunna Luckwu ◽  
Wagner Andrade ◽  
Luciane Pessoa ◽  
João Nascimento ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Hearing Threshold ◽  
Hormonal Contraceptives ◽  
Control Group ◽  
Hormonal Changes ◽  
High Frequencies ◽  
Hearing Thresholds ◽  
Hormonal Fluctuations ◽  
The Mean ◽  
Late Follicular Phase

Introduction The hormonal changes that occur during the menstrual cycle and their relationship with hearing problems have been studied. However, they have not been well explained. Objective The objective of our study is to investigate the variation in hearing thresholds in women during the menstrual cycle. Method We conducted a cohort and longitudinal study. It was composed of 30 volunteers, aged 18–39 years old, of which 20 were women during the phases of the menstrual cycle and 10 were men (control group) who underwent audiometry and impedance exams, to correlate the possible audiological changes in each phase of the menstrual cycle. Results There were significant changes in hearing thresholds observed during the menstrual cycle phases in the group of women who used hormonal contraceptives and the group who did not use such contraceptives. Improved hearing thresholds were observed in the late follicular phase in the group who did not use hormonal contraceptives and the hearing thresholds at high frequencies were better. Throughout the menstrual cycle phases, the mean variation was 3.6 db HL between weeks in the group who used hormonal contraceptives and 4.09 db HL in the group who did not use them. Conclusions The present study found that there may be a relationship between hearing changes and hormonal fluctuations during the menstrual cycle based on changes in the hearing thresholds of women. In addition, this study suggests that estrogen has an otoprotective effect on hearing, since the best hearing thresholds were found when estrogen was at its maximum peak.

Effects of CyberKnife therapy for vestibular schwannoma on hearing: a retrospective study

2018 ◽  
Vol 132 (9) ◽  
pp. 796-801
Author(s):  
O Çakır ◽  
G Berkiten ◽  
B Tutar ◽  
A B Yılmazer ◽  
T L Kumral ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Vestibular Schwannoma ◽  
Hearing Preservation ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Speech Discrimination ◽  
Before And After ◽  
Cyberknife Radiosurgery ◽  
The Mean

AbstractObjectivesTo evaluate the effects of CyberKnife stereotactic radiotherapy for the treatment of vestibular schwannoma on hearing, as evaluated by audiological tests.MethodsPatients with vestibular schwannoma were evaluated before and after CyberKnife radiosurgery. Evaluation included pure tone thresholds, speech discrimination scores, auditory brainstem responses and radiological signs.ResultsThe study comprised 26 patients diagnosed with vestibular schwannoma and subsequently treated with CyberKnife radiosurgery. The mean follow-up time was 16.4 months. The mean post-treatment hearing preservation rate was 69.23 per cent. There was no significant relationship between hearing loss after treatment and patient age, radiation dosage during treatment, or size of tumour. With regard to auditory brainstem responses, patients with hearing loss following treatment had a significantly higher inter-peak latency between waves I–III than patients with preserved hearing.ConclusionStereotactic CyberKnife radiosurgery is an excellent alternative treatment modality for patients with vestibular schwannoma, and results in acceptable preservation of hearing. Residual hearing following CyberKnife therapy is not significantly affected by factors such as age, size of tumour or dosage of treatment.

scholarly journals CREATINE KINASE-MB;

2017 ◽  
Vol 24 (03) ◽  
pp. 422-425
Author(s):  
Attia Anwar ◽  
Rizwan Faisal ◽  
Asifa Sharif
Keyword(s):  
Creatine Kinase ◽  
Myocardial Infarct ◽  
P Value ◽  
Treatment Results ◽  
Acute Myocardial Infarct ◽  
Creatine Kinase Mb ◽  
Before And After ◽  
Male Patients ◽  
The Mean ◽  
Study Setting

Objective: To compare the levels of creatine kinase-MB in male and femalepatients of acute myocardial infarction before and after the treatment. Study design:Comparative study. Setting: Faisalabad Institute of Cardiology, Faisalabad, Pakistan. Period:08 months, March 2014 to September 2014. Material & Methods: Total 60 patients of acutemyocardial infarction were enrolled in the study; 30 males and 30 females. The creatine kinase-MB levels of all the patients were checked and compared before starting the treatment for acutemyocardial infarction and then after 24 &48 hours of treatment. Results: The results of the studyshown that the mean of CK-MB levels before treatment was high in male as compared to femalepatients with p-value < 0.01. Similarly the comparison of mean CK-MB levels after 24 and 48hours of treatment were also found to be significantly higher in male patients with p-value <0.01each. Conclusion: The levels of CK-MB in male acute myocardial infarct patients were highboth before and after the treatment.

Longitudinal analysis of hearing before and after radiosurgery for vestibular schwannoma

2012 ◽  
Vol 117 (5) ◽  
pp. 877-885 ◽  
Author(s):  
Shoji Yomo ◽  
Romain Carron ◽  
Jean-Marc Thomassin ◽  
Pierre-Hugues Roche ◽  
Jean Régis
Keyword(s):  
Vestibular Schwannoma ◽  
Hearing Preservation ◽  
Tumor Control ◽  
Post Intervention ◽  
Accurate Analysis ◽  
Tumor Margins ◽  
Before And After ◽  
The Mean ◽  
The Impact

Object The aim of this study was to perform an accurate analysis of changes in hearing in patients with vestibular schwannoma (VS) who have undergone Gamma Knife surgery (GKS) and distinguish the impact of radiosurgery from the natural course of hearing deterioration due to the tumor itself. Methods This study was a retrospective review of prospectively collected patient data. A group of 154 patients with unilateral nonsurgically treated VS was conservatively monitored for more than 6 months and then treated with GKS between July 1997 and September 2005. They were followed up with serial clinical examination, MRI, and audiometry. The annual hearing decrease rate (AHDR) was measured before and after radiosurgery, and the possible prognostic factors for hearing preservation were investigated. Results The mean dose prescribed to the tumor margins was 12.1 Gy. The mean radiological follow-up period after GKS was 60 months (range 7–123 months). The tumor control rate was 94.8%, and 8 patients underwent subsequent intervention due to tumor progression. The mean audiological follow-up times before and after GKS were 22 and 52 months, respectively. The mean AHDRs before and after GKS were 5.39 dB/year (95% CI 3.31–7.47 dB/year) and 3.77 dB/year (95% CI 3.13–4.40 dB/year), respectively (p > 0.05). The mean pre- and post-GKS AHDRs in patients who initially had Gardner-Robertson (GR) Class I hearing were −0.57 dB/year (95% CI −2.95 to 1.81 dB/year) and 3.59 dB/year (95% CI 2.52–4.65 dB/year), respectively (p = 0.007). The mean pre- and post-GKS AHDRs in patients who initially had GR Class II hearing were 5.09 dB/year (95% CI 1.36–8.82 dB/year) and 4.98 dB/year (95% CI 3.86–6.10 dB/year), respectively (p > 0.05). A subgroup of 80 patients had both early and late post-intervention AHDR assessment (with early referring to the period from GKS to the assessment closest to the 2-year follow-up point and late referring to the period from that assessment to the most recent one); in these patients, the mean early post-GKS AHDR was 5.86 dB/year (95% CI 4.25–7.50 dB/year) and the mean late post-GKS AHDR was 1.86 dB/year (95% CI 0.77–2.96 dB/year) (p < 0.001). A maximum cochlear dose of less than 4 Gy was found to be the sole prognostic factor for hearing preservation. Conclusions The present study demonstrated the absence of an increase in AHDR after radiosurgery as compared with the preoperative AHDR. There was even a trend indicating a reduction in the annual hearing loss after radiosurgery over the long term. To fully elucidate a possible protective effect of radiosurgery, longer-term follow-up with a larger group of patients will be required.

scholarly journals Characterization of the performance of brazilian adolescents in the Pitch Pattern Sequence (PPS) test developed by Auditec®

Revista CEFAC ◽  
2019 ◽  
Vol 21 (2) ◽  
Author(s):  
Taina Maiza Bilinski Nardez ◽  
Laura Mochiatti Guijo ◽  
Priscila de Araújo Lucas ◽  
Ana Cláudia Vieira Cardoso
Keyword(s):  
Mean Value ◽  
Normative Values ◽  
Inclusion Criteria ◽  
Acoustic Reflex ◽  
Pitch Pattern ◽  
Hearing Thresholds ◽  
Pattern Sequence ◽  
The Mean ◽  
Normative Value

ABSTRACT Purpose: to characterize the performance of Brazilian adolescents in the Pitch Pattern Sequence (PPS) test and compare the results with Auditec® normative values. Methods: 26 adolescents enrolled in elementary or secondary education, of both sexes, and between 12 and 18 years, participated in the study. The inclusion criteria adopted were: a) no alterations in the visual inspection of the external acoustic meatus; b) hearing thresholds within the normal range for both ears, that is, values equal to or lower than 25dBHL; c) bilateral type “A” tympanometric curve, d) presence of acoustic reflex, contralateral mode, in the frequencies of 500, 1000 and 2000Hz, in both ears, typical auditory behavior according to the Scale of Auditory Behaviors (SAB) or greater than 46 points. For adolescents, who met the inclusion criteria, the PPS (Auditec® version) was applied, binaurally, at 50dBSL. The findings were analyzed in a descriptive and inferential manner. Results: statistical analysis showed significance only for the comparison of the mean value of 88.10%, a result obtained in the PPS performed by Brazilians, when compared to the normative value (included) suggested by Auditec®, in which the mean was 96%. Conclusion: the findings of this study demonstrated that the values obtained in the PPS, Auditec® version, in the Brazilian population, were similar to those presented in the international literature.

scholarly journals Prehospital Use of Ketamine: Effectiveness in Critically Ill and Injured Patients

2019 ◽  
Vol 184 (Supplement_1) ◽  
pp. 542-544 ◽  
Author(s):  
John Zietlow ◽  
Kathy Berns ◽  
Donald Jenkins ◽  
Scott Zietlow
Keyword(s):  
Critically Ill ◽  
Time Frame ◽  
Pain Scale ◽  
Intravenous Route ◽  
Medical Illness ◽  
Before And After ◽  
Male Patients ◽  
The Mean ◽  
Injured Patients ◽  
The Military

Abstract Background The military use of ketamine is well established. The benefits of prehospital civilian use have not been extensively reported. Methods A retrospective review was performed of patients with prehospital ketamine use in Mayo One’s air and critical care ground transport. Results The medical records were reviewed from 2014 to 2016 to assess the efficacy of Ketamine. During this time frame, 158 (167 instances) patients were treated with ketamine for analgesia (38%), sedation (44%), or procedural (18%) use. The patient population had a mean age of 49 (range: 1–100), with 105 (67%) male patients. Indications included trauma (69%), which was further broken down into blunt (57%), penetrating (4%), and miscellaneous (8%), and medical illness (31%). The mean ketamine dose was 52.6 mg (range: 5–200 mg) via intravenous route. Ketamine was utilized in 61% of patients after other medications were ineffective. Overall success rate was 98%. Mean pain scale before and after ketamine use was 9/10 and 3/10, respectively. Ketamine use increased yearly from 21 (13%) in 2014, 56 (36%) in 2015, and 81 (51%) in 2016. Conclusion Prehospital ketamine use is effective alone or in conjunction with other medications for analgesia, sedation, and procedural use in trauma and critically ill patients with minimal hemodynamic and respiratory consequences.

Analysis of taste disturbance before and after surgery in patients with vestibular schwannoma

2003 ◽  
Vol 99 (6) ◽  
pp. 999-1003 ◽  
Author(s):  
Katsushige Watanabe ◽  
Nobuhito Saito ◽  
Makoto Taniguchi ◽  
Takaaki Kirino ◽  
Tomio Sasaki
Keyword(s):  
Vestibular Schwannoma ◽  
Taste Perception ◽  
Tumor Removal ◽  
Taste Disturbance ◽  
Content Type ◽  
Before And After ◽  
History Of ◽  
Vs Removal ◽  
The Mean ◽  
Fine Print

Object. The frequency, nature, and history of subjective taste disturbance before and after vestibular schwannoma (VS) surgery was investigated. Methods. Personal interviews were conducted in 108 patients with unilateral VS. Abnormalities in taste perception, either a significant reduction or a change in character, were experienced by 31 patients (28.7%) before surgery and by 37 (34.3%) after tumor removal. Preoperative taste disturbance worsened after surgery in five (16.1%) of the 31 patients, remained unchanged in eight (25.8%), improved in two (6.5%), and became normal in 16 (51.6%). Taste disturbance occurred postoperatively in 22 (28.6%) of 77 patients who had experienced no preoperative taste disturbance. The mean onset of the abnormality after resection was 1.1 ± 1.7 months. Postoperative taste disturbance resolved in 24 of the 37 patients (64.9%) within 1 year after onset. Conclusions. Subjective taste disturbance was common before and after VS removal, and the natural history of this condition was very variable in the pre- and postoperative periods. All patients who undergo surgery for VS should receive appropriate counseling about the likelihood and course of postoperative complications, including dysfunction of the sensory component of the facial nerve.

scholarly journals The influence of the use of earphones in the of young people’s hearing

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Juelma Tavares ◽  
Cristina Nazaré
Keyword(s):  
Hearing Loss ◽  
Young People ◽  
Otoacoustic Emissions ◽  
Warning Sign ◽  
High Frequencies ◽  
Distortion Product ◽  
Hearing Thresholds ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Abstract Background Listening music is extremely important in our day life, but studies indicate that young people who use earphones for long periods tend to develop hearing problems. The aim of this study was to evaluate the hearing of young people who use earphones to listen to music very often and occasionally, and observe if there are differences between them. Methods The sample was composed by 2 groups (n = 15 in each) of young people, students in higher education (18–24 years) who use earphones to listen music every week, with Group 1 using earphones occasionally and Group 2 very often. Otoscopy, pure tone audiogram (PTA: 0.125–8 kHz), high frequencies (HF: 9–12.5 kHz) and distortion product otoacoustic emissions (DPOAEs: 2–10 kHz) was performed. Results There were statistically significant differences between groups in PTA (0.125 and 0.5 kHz in right ear - RE) and DPOAEs (7.5, 8.3, 9.1 and 10 kHz in RE and 6.2, 7.5, 10 kHz in left ear), being the means of hearing thresholds (PTA and HF) higher and the means of the DPOAE’s amplitudes lower in Group 2, in most frequencies. Despite all individuals had normal hearing thresholds in PTA, in HF at 11.2 KHz in RE, the mean of threshold in Group 2 was over 20 dBHL. Conclusions The differences found between groups can be a warning sign for future hearing loss in young people who use earphones very often to listen to music, so it is important to raise awareness among young people for the prevention of hearing loss and change behaviours.

Perbedaan Pengetahuan Siswa Tentang Penyakit Hepatitis A Sebelum Dan Sesudah Penyuluhan Di MTsN 02 Bondowoso Tahun 2015

2017 ◽  
Vol 4 (2) ◽  
pp. 14
Author(s):  
Putri Megasari
Keyword(s):  
Hepatitis A ◽  
Hepatitis Virus ◽  
Sampling Technique ◽  
Mean Value ◽  
Test Design ◽  
The World ◽  
Before And After ◽  
Post Test ◽  
The Mean ◽  
Paired T Test

Hepatitis has become a health problem in the world. The hepatitis virus infected many people. According to the teacher of MTsN 02 Bondowoso more than 20 students have hepatitis A viral infection. The purpose of this research was to know the differences of students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study used pre-experimental (pre-post test design). This study used stratified random sampling technique, 127 students from 270 sample involved this research,and 143 students was excluded. We used questionnaires to collect data. The results showed that the mean value of the students 'knowledge about hepatitis A before counseling in MTsN 02 Bondowoso 2015 was 83.96 with the lowest value of 37.5 and the highest value was 100. The mean value of the students' knowledge about hepatitis A after counseling in MTsN 02 Bondowoso 2015 was 93.21 with the lowest value waf 62.5 and the highest value was 100. Paired t test showed that t (-9.07) > t table (1.98), the null hypothesis (H0) was rejected. There was a difference between students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study showed that routine counseling by healthcare provider was important to prevent hepatitis A infection.; Keywords: counseling, knowledge of students, hepatitis

Quality of Life for Children with Persistent Sinonasal Symptoms

2003 ◽  
Vol 128 (1) ◽  
pp. 17-26 ◽  
Author(s):  
David J. Kay ◽  
Richard M. Rosenfeld
Keyword(s):  
Quality Of Life ◽  
Clinical Care ◽  
Longitudinal Change ◽  
Good Test ◽  
Routine Clinical Care ◽  
Before And After ◽  
The Mean ◽  
The Individual ◽  
Sinonasal Symptoms

OBJECTIVE: The goal was to validate the SN-5 survey as a measure of longitudinal change in health-related quality of life (HRQoL) for children with persistent sinonasal symptoms. DESIGN AND SETTING: We conducted a before and after study of 85 children aged 2 to 12 years in a metropolitan pediatric otolaryngology practice. Caregivers completed the SN-5 survey at entry and at least 4 weeks later. The survey included 5 symptom-cluster items covering the domains of sinus infection, nasal obstruction, allergy symptoms, emotional distress, and activity limitations. RESULTS: Good test-retest reliability ( R = 0.70) was obtained for the overall SN-5 score and the individual survey items ( R ≥ 0.58). The mean baseline SN-5 score was 3.8 (SD, 1.0) of a maximum of 7.0, with higher scores indicating poorer HRQoL. All SN-5 items had adequate correlation ( R ≥ 0.36) with external constructs. The mean change in SN-5 score after routine clinical care was 0.88 (SD, 1.19) with an effect size of 0.74 indicating good responsiveness to longitudinal change. The change scores correlated appropriately with changes in related external constructs ( R ≥ 0.42). CONCLUSIONS: The SN-5 is a valid, reliable, and responsive measure of HRQoL for children with persistent sinonasal symptoms, suitable for use in outcomes studies and routine clinical care.

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