scholarly journals A new automated system for the preparation of sclerosant foam: A study of the physical characteristics produced and the device settings required

2020 ◽  
Vol 35 (9) ◽  
pp. 724-733
Author(s):  
Enric Roche ◽  
Ramon Pons ◽  
Oriol Roche ◽  
Antoni Puig
Keyword(s):  
Half Life ◽  
Bubble Diameter ◽  
Physical Characteristics ◽  
Automated System ◽  
Sodium Tetradecyl Sulfate ◽  
Liquid Ratio ◽  
Sclerosing Agents ◽  
Single Use ◽  
Gas To Liquid

Objectives To determine the quality of sclerosant foam produced with an automated preparation system with multiple combinations of sclerosing agents, gases, and device settings. Methods Single-use mixing capsules filled with air or O2/CO2 and polidocanol (0.25, 1, or 3%) or sodium tetradecyl sulfate (0.2 or 1%) were coupled to a customized magnetic stirrer. Stirring speed and time were adjusted between 1500 and 4000 r/min and 30 and 60 s, respectively, and characteristics of the foam produced were measured: half-life, bubble diameter, and gas-to-liquid ratio. Results With optimized device settings, the following foam characteristics were obtained: half-life range, 1.4 ± 0.9 to 5.2 ± 0.6 min; bubble diameter, 84 ± 14 to 119 ± 6 µm; and gas-to-liquid ratio, 5:1–7:1. Sodium tetradecyl sulfate foam was quicker to form than polidocanol but faster to degrade. Foams with low sclerosant concentrations and O2/CO2 required higher speed and longer time. Conclusions Suitable foam characteristics could be obtained with all combinations of sclerosing agent, concentration, and gas.

scholarly journals Physical Characteristics and Microbial Quality of Ostrich Meat in Relation to the Type of Packaging and Refrigerator Storage Time

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3445
Author(s):  
Olaf K. Horbańczuk ◽  
Artur Jóźwik ◽  
Jarosław Wyrwisz ◽  
Joanna Marchewka ◽  
Agnieszka Wierzbicka
Keyword(s):  
Storage Time ◽  
Modified Atmosphere Packaging ◽  
Physical Characteristics ◽  
Modified Atmosphere ◽  
Packaging System ◽  
Initial Ph ◽  
Viable Bacteria ◽  
L Value ◽  
Meat Samples

The aim of this study was to evaluate the effect of the packaging system type on the physical characteristics and microbial changes in ostrich meat during refrigerated storage. The applied packaging systems were vacuum packaging (VP) and modified atmosphere packaging (MAP) using two combinations of gases: MAP1 (40% O2/40% CO2/20% N2) and MAP2 (60% O2/30% CO2/10% N2). Eight meat samples were obtained in three replicates for all parameters, except for pH, for which six replicates were obtained from the M. ilifibularis (IF) muscle, and were stored in a refrigerator at 2 °C and analyzed at 0, 4, 8, 12 and 16 days for the effect of packaging methods on physical meat quality. The initial pH (5.99) decreased at the end of the storage time for MAP1 to 5.81, whereas VP was stable from day 0 to 12 and increased up to 6.08 on day 16. Regarding meat color, the L* value increased during storage for MAP1 and MAP2 from 36.99 to 40.75 and 41.60, respectively, whereas it declined for VP to 34.22. The same tendencies were reported for redness (a*) and yellowness (b*). Drip loss was the lowest in MAP1 and highest in VP. The lowest total viable bacteria counts were identified in VP, as compared to MAP1 and MAP2.

The structure and application of an automated system for monitoring passenger traffic

2021 ◽  
Vol 14 (3) ◽  
pp. 4-11
Author(s):  
Evgeniy Anikeev
Keyword(s):  
Data Collection ◽  
General Structure ◽  
Automated System ◽  
Passenger Transport ◽  
Service Levels ◽  
Passenger Traffic ◽  
Advantages And Disadvantages ◽  
Transport Services ◽  
Transport Control

Various methods of collecting data on passenger traffic, their advantages and disadvantages are considered. It is shown that in order to improve the quality of transport services, it is necessary to regularly collect and refine data on passenger traffic. The goals and methods of obtaining information about passenger traffic in the system of municipal passenger transport are indicated. All currently existing methods are divided into three categories: data collection using technical means, data collection with the help of censors and volunteers, and interpretation of fare payments. All the methods presented in the article were compared in terms of labor intensity, costs and accuracy of the results obtained. The advantages and disadvantages of each method are considered. The general structure of an automated system for collecting data on passenger traffic is presented. The necessity of creating a centralized system for collecting and processing data associated with all passenger transport control systems has been substantiated. The tasks solved by this system at all levels of transport services for passengers are shown. Each of the tasks is assigned to one of three service levels: pre-transport, transport and post-transport. It is shown that only solving problems at all levels can ensure high-quality operation of the municipal passenger transport system.

scholarly journals Development and evaluation of an automated system for testing current meters

2016 ◽  
Vol 20 (2) ◽  
pp. 181-187 ◽  
Author(s):  
Ezequiel Saretta ◽  
Antonio P. de Camargo ◽  
Tarlei A. Botrel ◽  
Marinaldo F. Pinto ◽  
Geancarlo T. Katsurayama ◽  
...  
Keyword(s):  
User Interface ◽  
Data Acquisition ◽  
Flow Velocity ◽  
Reference Value ◽  
Vertical Axis ◽  
Automated System ◽  
Step Motor ◽  
Simple Task ◽  
Rivers And Streams

ABSTRACT Current meters are equipment widely used for estimating flow velocity in rivers and streams. Periodic calibrations of current meters are important to ensure the quality of measurements, but the required testing facilities are complex and only available in a few institutions. However, advances in electronics and automation may contribute to developing simple and reliable calibration systems. Thus, this study aimed to develop an automated system for testing current meters, which consisted of a trapezoidal channel, a step motor, a tow car and a management system, composed of a supervisory application and microprocessed modules to control the motor and the data acquisition. Evaluations of the displacement velocity showed that it matched the reference value up to 1.85 m s-1 for a vertical-axis current meter and 2.3 m s-1 for a horizontal-axis one. The developed system showed reliability during tests, for both current meter movement and data acquisition. The management of the system based on the developed modules and the supervisory application improved its user interface, turning all the procedure into a simple task.

Rapid Somatic Mutation Testing in Colorectal Cancer by Use of a Fully Automated System and Single-Use Cartridge: A Comparison with Next-Generation Sequencing

2018 ◽  
Vol 3 (2) ◽  
pp. 178-184 ◽  
Author(s):  
M Rabie Al-Turkmani ◽  
Kelley N Godwin ◽  
Jason D Peterson ◽  
Gregory J Tsongalis
Keyword(s):  
Colorectal Cancer ◽  
Next Generation Sequencing ◽  
Ffpe Tissue ◽  
Braf V600e ◽  
Automated System ◽  
Next Generation ◽  
Tissue Samples ◽  
Tissue Sections ◽  
Single Use ◽  
Generation Sequencing

AbstractBackgroundMolecular tests have been increasingly used in the management of various cancers as more targeted therapies are becoming available as treatment options. The Idylla™ system is a fully integrated, cartridge-based platform that provides automated sample processing (deparaffinization, tissue digestion, and DNA extraction) and real-time PCR-based mutation detection with all reagents included in a single-use cartridge. This retrospective study aimed at evaluating both the Idylla KRAS and NRAS-BRAF-EGFR492 Mutation Assay cartridges (research use only) against next-generation sequencing (NGS) by using colorectal cancer (CRC) tissue samples.MethodsForty-four archived formalin-fixed paraffin-embedded (FFPE) CRC tissue samples previously analyzed by targeted NGS were tested on the Idylla system. Among these samples, 17 had a mutation in KRAS proto-oncogene, GTPase (KRAS), 5 in NRAS proto-oncogene, GTPase (NRAS), and 12 in B-Raf proto-oncogene, serine/threonine kinase (BRAF) as determined using the Ion AmpliSeq 50-gene Cancer Hotspot Panel v2. The remaining 10 samples were wild-type for KRAS, NRAS, and BRAF. Two 10-μm FFPE tissue sections were used for each Idylla run, 1 for the KRAS cartridge, and 1 for the NRAS-BRAF-EGFR492 cartridge. All cases met the Idylla minimum tumor content requirement for KRAS, NRAS, and BRAF (≥10%). Assay reproducibility was evaluated by testing commercial controls derived from human cell lines, which had an allelic frequency of 50% and were run in triplicate.ResultsThe Idylla system successfully detected all mutations previously identified by NGS in KRAS (G12C, G12D, G12V, G13D, Q61K, Q61R, A146T), NRAS (G12V, G13R, Q61H), and BRAF (V600E). Compared with NGS, Idylla had a sensitivity of 100%. Analysis of the mutated commercial controls demonstrated agreement with the expected result for all samples and 100% reproducibility. The Idylla system produced results quickly with a turnaround time of approximately 2 h.ConclusionThe Idylla system offers reliable and sensitive testing of clinically actionable mutations in KRAS, NRAS, and BRAF directly from FFPE tissue sections.

scholarly journals Users’ Satisfaction in CityWaterfront: The Case of Jeddah Corniche

2019 ◽  
Vol 3 (2) ◽  
pp. 100
Author(s):  
Ghadeer Alawi ◽  
Lobna Mostafa
Keyword(s):  
Quality Of Life ◽  
Physical Health ◽  
Citizen Participation ◽  
Social Cohesion ◽  
Physical Characteristics ◽  
Present Condition ◽  
Urban Management ◽  
Open Spaces ◽  
Level Of Satisfaction

Recreational waterfront developments can be only superficially pleasant as they lack substantial design qualities needed for their user’s comfort. Enhancing the user’s comfort and satisfaction will encourage people to spend more time outdoors, with the potential to improve their physical health, enrich their social cohesion, and enhance the overall quality of life. The objective of this study is to investigate the extent to which the physical characteristics of open spaces can contribute to the user’s satisfaction with space. The study evaluates the user’s perception of satisfaction in the recent development of Jeddah North Corniche and provides solutions to enhance this issue. The methodologies applied in this study are structured questioner survey, which focuses on understanding the current user’s preference and their level of satisfaction regarding the present condition. This increase the emphasis on representative citizen participation, who are usually not consulted in planning issues. The findings of this research involve the development of urban management principles for the adoption of sustainable waterfronts with the consideration of culture. The outcome should contribute to the Saudi 2030 vision by: Enhancing livability of Saudi Cities through improving the landscape and facilities of Jeddah urban waterfronts, and to encourage citizens to exercise at least once per week through enhancing the microclimate condition of waterfronts open spaces.

scholarly journals Developing a Measuring System for Monitoring the Thickness of the 6 m Wide HDPE/LDPE Polymer Geomembrane with Its Continuous Flow Using Automation Equipment

2021 ◽  
Vol 11 (21) ◽  
pp. 10045
Author(s):  
Tatyana Nikonova ◽  
Olga Zharkevich ◽  
Essim Dandybaev ◽  
Murat Baimuldin ◽  
Leonid Daich ◽  
...  
Keyword(s):  
Continuous Flow ◽  
High Density Polyethylene ◽  
Foreign Bodies ◽  
Automated System ◽  
Measuring System ◽  
Original Design ◽  
Software Complex ◽  
Automation Equipment ◽  
Production Conditions

As a result of R&D, a measuring system for controlling the thickness of the HDPE/LDPE (high-density polyethylene/low-density polyethylene) polymer geomembrane was developed using automation equipment. The relevance of this work consists of the development of a domestic, relatively inexpensive system for controlling the thickness of the HDPE/LDPE polymer geomembrane in production conditions based on modern equipment for enterprise automation. The scientific novelty consists of the use of original design solutions in the development of hardware and software complex mechanisms that allow controlling the thickness of the HDPE/LDPE polymer geomembrane layers along the entire width of the shaft, excluding deformation of the film as a result of foreign bodies entering during extrusion, cuts, monitoring the quality of the film in real time, as well as the possibility of analyzing the measured parameters in the database of the automated system.

scholarly journals METHOD OF EVALUATION OF FUNCTIONAL SECURITY OF INFORMATION TECHNOLOGIES FOR CREATION OF WARRANTY AUTOMATED SYSTEMS

2020 ◽  
Vol 3 (7) ◽  
pp. 153-164 ◽  
Author(s):  
Hennadii Hulak
Keyword(s):  
Information Technologies ◽  
Linear Equations ◽  
Point Of View ◽  
Automated System ◽  
Special Role ◽  
Automated Systems ◽  
Systems Of Linear Equations ◽  
Method Of Evaluation

The components of ensuring the warranty of automated systems, which are subject to increased requirements in connection with their use in many sensitive areas of public activity, including national security and defense, critical industrial technologies, energy and communications, banking, environmental protection , technologies of legitimate distance learning, etc. Certain components can significantly affect the quality and reliability of information services in regulatory conditions. In particular, the special role of the functional security of the cryptographic subsystem in terms of supporting the performance of the automated system for its tasks and functions in general, as well as in terms of ensuring the confidentiality and integrity of information. The components of the cryptographic subsystem have been identified, the poor or incorrect operation of which negatively affects the security of these subsystems. The types of the most dangerous attacks on these subsystems are analyzed, their classification from the point of view of possibility of realization in modern scientific and technical conditions and depending on capacity of available computing means and technologies on the basis of which the most real and dangerous variant of realization of remote attacks on software implementation of cryptographic subsystem is defined. . Based on the analysis, a method for evaluating the quality of cryptographic transformations based on a modified algorithm for solving the problem of finding solutions of systems of linear equations with distorted right-hand parts using the so-called decoding based on "lists" of first-order "shortened" Reed-Muller codes is proved. the correctness of the proposed algorithm.

Computational Fluid Dynamics Analysis of Fluid Mixing in Single Use Bioreactors

2010 ◽  
Author(s):  
Robert Spall ◽  
Nephi Jones ◽  
Clinton Staheli
Keyword(s):  
Reference Frame ◽  
Bubble Diameter ◽  
Fluid Mixing ◽  
Balance Model ◽  
Transfer Coefficients ◽  
Sliding Mesh ◽  
Mesh Model ◽  
Computational Fluid Dynamics Analysis ◽  
Rotating Reference Frame ◽  
Single Use

CFD calculations were performed for a series of stirred, single use bioreactor vessels using both rotating reference frame and sliding mesh model approaches. Comparisons of quantities such as flow patterns, power numbers, and mixing times are presented. Calculations to predict mass transfer coefficients for a sparged 250L vessel were also performed using the rotating reference frame model. Results presented include those from a series of single, fixed bubble diameter calculations, and those which employed a population balance model consisting of 9 discrete bubble diameters.

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