Aerobic exercise for adolescent outpatients with persistent major depression: Feasibility and acceptability of moderate to vigorous group exercise in a clinically referred sample

2021 ◽  
pp. 135910452110007 ◽  
Author(s):  
Håkan Jarbin ◽  
Kristina Höglund ◽  
Gudmundur Skarphedinsson ◽  
Ann Bremander
Keyword(s):  
Major Depression ◽  
Aerobic Exercise ◽  
Aerobic Capacity ◽  
Exercise Intervention ◽  
Depressive Symptomatology ◽  
Well Being ◽  
Control Group ◽  
Clinically Referred ◽  
Persistent Depression ◽  
Comorbid Adhd

Aims: To assess feasibility and acceptability of exercise in clinically referred adolescents with major depression. Methods: Outpatients12 to 17 years with mild to moderate persistent depression participated in a supervised, pulse monitored, 14-week aerobic exercise but without control group. Primary outcome was adherence and secondary was clinician-rated Quick Inventory of Depressive Symptomatology – Adolescent (QIDS-A17-C), aerobic capacity, functioning, and well-being. Results: Twenty-one (66%) of 32 eligible adolescents with major depression with disease duration 2.4 (1.1–5.3) years and comorbid ADHD (71%) and anxiety disorders (62%) consented. Estimated maximum heart rate above 70% was achieved for mean 31.6 minutes, indicating that the intensity and duration of the exercise intervention was well received. Fourteen patients (67%) participated throughout the program and attended a median of 29 (81%, range 20–35) supporting satisfaction with the intervention by most patients. QIDS-A17-C score decreased compared to baseline at 15 weeks ( p < .001) and further at 1 year ( p < .001). Aerobic capacity improved during the intervention but was not maintained, while functioning improved and after 1 year also well-being. Conclusion: This 14 week moderate to vigorous aerobic exercise intervention was feasible and well accepted by most adolescents with persistent depression and extensive comorbidities.

scholarly journals The Changes of Premenstrual Symptoms after Aerobic Exercise Intervention

Jurnal NERS ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. 38
Author(s):  
Sirajudin Noor ◽  
Raihana Norfitri
Keyword(s):  
Health Education ◽  
Aerobic Exercise ◽  
Premenstrual Syndrome ◽  
Exercise Intervention ◽  
Pearson Correlation ◽  
Well Being ◽  
Physical Symptoms ◽  
T Test ◽  
Control Group ◽  
Before And After

Introduction: Premenstrual syndrome (PMS) is a group of physical symptoms, emotions and behaviors that occur cyclically during the luteal phase of the menstrual cycle and disappear after menstruation happened. Those symptoms might cause suffering for women and thus require treatment. Aerobic physical activity can raise the level of endorphins, decrease estrogen, increase oxygen transport in muscle and improve psychological well-being. The purpose of this study is to identify the differences in the effect of aerobic exercise and health education on the symptoms of premenstrual syndrome. Method: This study used quasy ekspriment with pre-posttest control group design. The research was conducted by comparing the symptoms of PMS complaints before and after treatment in the control group (education health) and the experimental group (aerobics).The research performed at the Academy of Nursing Intan Martapura and Midwifery Academy Banjarbaru with all students who registered as a student of the Academy of Nursing Intan Martapura and Midwifery Academy Banjarbaru as the subjects. The technique sampling used in this study was purposive sampling The number of sample was 40 respondents. Result: Based on pearson correlation test in cases and controls prior to treatment showed α > 0.05 (0.862), meant there was no correlation PMS between cases and controls. After treatment in cases and controls showed α <0.05 (0.018), mean there was a correlation between gymnastics aerobics with PMS complaints andPMS symptoms complaints, with the weak level of strength 0,373. From the comparative t-test in cases and controls prior to treatment showed signs ≥ 0.05 (0.862), means there was no difference of PMS complaints in cases and control group. After the treatment in cases and controls showed signs of < 0.05 (0.018), which means there was differences in symptoms of premenstrual complaints on cases that do aerobics with controls who received health education. From Paired t-test on cases before and after treatment in the form of aerobics showed sign result 0.000 < 0.05, which means that there were differences in symptoms of premenstrual complaints and menstrual complaints before and after aerobics exercise. In control group before and after treatment showed a sign of health education 0.056 ≥ 0.05 meant no differences on PMS complaints and PMS symptoms complaints between before and after the education. Analysis and Discusssion: For the students who had health complaints of PMS symptoms, it is suggested to perform regular aerobic exercise as one way to reduce the symptoms of PMS complaints.Keywords: PMS symptoms complaints, aerobics, health education

scholarly journals Effects of an 8-Week Yoga-Based Physical Exercise Intervention on Teachers’ Burnout

2021 ◽  
Vol 13 (4) ◽  
pp. 2104
Author(s):  
Francesca Latino ◽  
Stefania Cataldi ◽  
Francesco Fischetti
Keyword(s):  
Physical Exercise ◽  
Exercise Intervention ◽  
Maslach Burnout Inventory ◽  
Well Being ◽  
Emotional Awareness ◽  
Body Awareness ◽  
Control Group ◽  
Professional Burnout ◽  
Yoga Practice ◽  
Professional Educators

The purpose of this quasi-experimental study was to investigate the efficacy of an 8-week yoga-based physical exercise program to improve mental and emotional well-being and consequently reduce burnout among teachers. We considered yoga because it is a discipline that enhances body awareness and encourages the contact with nature and the respect for every form of life, with a view to a more sustainable and greener global system. We recruited 40 professional educators (40–47 years), teachers in a public high school who reported perceiving signs of stress and emotional discomfort. We randomly assigned the 40 professional educators to either an experimental yoga practice (~60 min, twice a week) group (n = 20) or a control group (n = 20) that received a nonspecific training program (~60 min, twice a week). At baseline and after training we administered the Maslach Burnout Inventory: Educators Survey (MBI-ES) and the State Mindfulness Scale (SMS) to assess teachers’ perceived level of awareness and professional burnout. We found a significant Time × Group interaction for the MBI-ES and SMS, reflecting a meaningful experimental group improvement (p < 0.001). No significant pre–post changes were found in the control group. The results suggest that an 8-week yoga practice could aid teachers to achieve a greater body and emotional awareness and prevent professional burnout.

scholarly journals Brain Structure, Cardiorespiratory Fitness, and Executive Control Changes after a 9-Week Exercise Intervention in Young Adults: A Randomized Controlled Trial

Life ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 292
Author(s):  
Lina Zhu ◽  
Qian Yu ◽  
Fabian Herold ◽  
Boris Cheval ◽  
Xiaoxiao Dong ◽  
...  
Keyword(s):  
Young Adults ◽  
Aerobic Exercise ◽  
Cardiorespiratory Fitness ◽  
Executive Control ◽  
Brain Structure ◽  
Grey Matter ◽  
Exercise Intervention ◽  
Exercise Group ◽  
Control Group ◽  
Younger Adults

Cardiorespiratory fitness (CRF) is assumed to exert beneficial effects on brain structure and executive control (EC) performance. However, empirical evidence of exercise-induced cognitive enhancement is not conclusive, and the role of CRF in younger adults is not fully understood. Here, we conducted a study in which healthy young adults took part in a moderate aerobic exercise intervention program for 9 weeks (exercise group; n = 48), or control condition of non-aerobic exercise intervention (waitlist control group; n = 72). Before and after the intervention period maximal oxygen uptake (VO2max) as an indicator of CRF, the Flanker task as a measure of EC performance and grey matter volume (GMV), as well as cortical thickness via structural magnetic resonance imaging (MRI), were assessed. Compared to the control group, the CRF (heart rate, p < 0.001; VO2max, p < 0.001) and EC performance (congruent and incongruent reaction time, p = 0.011, p < 0.001) of the exercise group were significantly improved after the 9-week aerobic exercise intervention. Furthermore, GMV changes in the left medial frontal gyrus increased in the exercise group, whereas they were significantly reduced in the control group. Likewise, analysis of cortical morphology revealed that the left lateral occipital cortex (LOC.L) and the left precuneus (PCUN.L) thickness were considerably increased in the exercise group, which was not observed in the control group. The exploration analysis confirmed that CRF improvements are linked to EC improvement and frontal grey matter changes. In summary, our results support the idea that regular endurance exercises are an important determinant for brain health and cognitive performance even in a cohort of younger adults.

scholarly journals Aerobic exercise improves hippocampal blood flow for hypertensive Apolipoprotein E4 carriers

2021 ◽  
pp. 0271678X2199034
Author(s):  
Carolyn S Kaufman ◽  
Robyn A Honea ◽  
Joseph Pleen ◽  
Rebecca J Lepping ◽  
Amber Watts ◽  
...  
Keyword(s):  
Blood Flow ◽  
Aerobic Exercise ◽  
Genetic Risk ◽  
Exercise Intervention ◽  
Late Onset ◽  
Control Group ◽  
Carrier Status ◽  
Or Education ◽  
Exercise Interventions ◽  
Apolipoprotein E4

Cerebrovascular dysfunction likely contributes causally to Alzheimer’s disease (AD). The strongest genetic risk factor for late-onset AD, Apolipoprotein E4 ( APOE4), may act synergistically with vascular risk to cause dementia. Therefore, interventions that improve vascular health, such as exercise, may be particularly beneficial for APOE4 carriers. We assigned cognitively normal adults (65–87 years) to an aerobic exercise intervention or education only. Arterial spin labeling MRI measured hippocampal blood flow (HBF) before and after the 52-week intervention. We selected participants with hypertension at enrollment (n = 44). For APOE4 carriers, change in HBF (ΔHBF) was significantly ( p = 0.006) higher for participants in the exercise intervention (4.09 mL/100g/min) than the control group (−2.08 mL/100g/min). There was no difference in ΔHBF between the control (−0.32 mL/100g/min) and exercise (−0.54 mL/100g/min) groups for non-carriers (p = 0.918). Additionally, a multiple regression showed an interaction between change in systolic blood pressure (ΔSBP) and APOE4 carrier status on ΔHBF ( p = 0.035), with reductions in SBP increasing HBF for APOE4 carriers only. Aerobic exercise improved HBF for hypertensive APOE4 carriers only. Additionally, only APOE4 carriers exhibited an inverse relationship between ΔSBP and ΔHBF. This suggests exercise interventions, particularly those that lower SBP, may be beneficial for individuals at highest genetic risk of AD. ClinicalTrials.gov Identifier: NCT02000583

The association of innate and acquired aerobic capacity with resilience in healthy adults: Protocol for an eight-week randomized controlled web-based physical exercise intervention study (Preprint)

2021 ◽  
Author(s):  
David Tobias Ochmann ◽  
Keito F A Philippi ◽  
Peter Zeier ◽  
Magdalena Sandner ◽  
Barlo Hillen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Exercise ◽  
Aerobic Capacity ◽  
Exercise Intervention ◽  
Intervention Group ◽  
Control Group ◽  
Active Lifestyle ◽  
Web Based ◽  
Before And After ◽  
Physically Inactive

BACKGROUND Physical activity ameliorates chronic stress. Latest research suggests a relation between resilience and physical fitness. Beneficial adaptations of the hypothalamic-pituitary-adrenal axis, the sympathetic nervous system, the endocannabinoid system, and the tryptophan pathway, induced by an active lifestyle, are considered to be resilience conducive. However, detailed knowledge on the molecular link between the effects of acute and chronic physical exercise and an improved resilience is missing. OBJECTIVE Therefore, we implement a human exercise intervention trial addressing the main hypotheses: (1) web-based exercise training improves aerobic capacity of physically inactive adults, which (2) is accompanied by improved resilience. In this setting, we will analyze the relation of resilience parameters with innate and acquired aerobic capacity as well as circulating signaling molecules. METHODS 70 healthy physically inactive (<150min/week physical activity) adults (18-45y) will be randomly assigned to an intervention or control group. Participants in the intervention group receive weekly training utilizing progressive endurance and interval running individually adapted to their training performance via web-based physician support. A standardized incremental treadmill exercise test is performed before and after the intervention period of eight weeks to determine innate and acquired aerobic capacity. Before and after the intervention psychological tests and questionnaires that characterize parameters implicated in resilience (including impulse control, working memory, stress coping, emotion regulation) will be applied. Blood, and saliva will be sampled for analysis of lactate, cortisol, endocannabinoids, catecholamines, kynurenic acid, cell-free DNA and further circulating signal transducers. Statistical analysis will provide comprehensive knowledge on the relation of aerobic capacity and resilience, and furthermore, the capacity of peripheral factors to mediate the promoting effects of exercise on resilience. RESULTS The study was registered in October 2019. Enrollment began in September 2019. Out of 161 subjects, who were initially screened via telefon survey, 43 fulfilled the inclusion criteria and were included. Among the 17 participants in the intervention group, and 14 participants in the control group, who completed the study (total 31), no serious adverse event has been reported. Four participants withdrew during the programm (individual reasons), and 8 participants have not yet completed or begun the program due to the Covid-19 pandemic. Enrollment and data analysis are ongoing, and results are expected to be submitted for publication in October 2021. CONCLUSIONS Our study aims to demonstrate that an increase in physical activity with a simultaneous improvement in aerobic capacity is associated with an increase in resilience. This study design allows to investigate the effect of an active lifestyle on circulating molecular marker levels and their relationship to resilience factors. This will offer novel approaches for the diagnosis of depression and the therapy by exercise prescription. CLINICALTRIAL DRKS00018078, registered October 02, 2019, German Clinical Trials Register. Retrospectively registered: First participant September 10, 2019.

Aerobic exercise intervention improves aerobic capacity and movement initiation in Parkinson's disease patients

2002 ◽  
Vol 17 (2) ◽  
pp. 161-168 ◽  
Author(s):  
John L. Bergen ◽  
Tonya Toole ◽  
Robert G. Elliott III ◽  
Brian Wallace ◽  
Keith Robinson ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Aerobic Capacity ◽  
Exercise Intervention ◽  
Movement Initiation

scholarly journals Sex Moderates the Effect of Aerobic Exercise on Some Aspects of Cognition in Cognitively Intact Younger and Middle-Age Adults

2019 ◽  
Vol 8 (6) ◽  
pp. 886 ◽  
Author(s):  
Yaakov Stern ◽  
Seonjoo Lee ◽  
David Predovan ◽  
Richard P. Sloan
Keyword(s):  
Aerobic Exercise ◽  
Aerobic Capacity ◽  
Processing Speed ◽  
Exercise Intervention ◽  
Parallel Group ◽  
Normal Individuals ◽  
Exercise Effect ◽  
Underlying Mechanisms ◽  
Age Range ◽  
The Impact

We recently reported the results of a randomized, parallel-group, observer-masked, community-based clinical trial of 132 cognitively normal individuals aged 20–67 with below median aerobic capacity who were randomly assigned to one of two 6-month, four-times-weekly conditions: aerobic exercise and stretching/toning. We now assessed potential sex moderation on exercise-related changes in aerobic capacity, BMI and cognitive function. There was no sex moderation of the effect of aerobic exercise on aerobic capacity or BMI. We had previously reported an effect of aerobic exercise on executive function that was moderated by age. We found additional moderation by sex, such that in any age range men improved more than women. Processing speed showed significant sex moderation but not significant age moderation. In men, processing speed significantly improved by week 12 (b = 0.35, p = 0.0051), but the effect was diminished relative to week 12 at week 24 (b = 0.24, p = 0.0578). In women, there was no exercise effect at either time point (week 12: b = −0.06, p = 0.4156; week 24: b = −0.11, p = 0.1841). Men benefited cognitively more than women from aerobic exercise. This study highlights the importance of using sex-disaggregated analyses when assessing the impact of physical exercise intervention, and the need to ascertain the underlying mechanisms for differential cognitive benefit by sex.

The effect of aerobic exercise on the metabolic risk profile of breast cancer survivors 2-6 months post chemotherapy.

2011 ◽  
Vol 29 (27_suppl) ◽  
pp. 244-244
Author(s):  
E. M. Guinan ◽  
J. M. Hussey ◽  
J. M. Walsh ◽  
M. J. Kennedy ◽  
E. M. Connolly
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Aerobic Exercise ◽  
Breast Cancer Survivors ◽  
Exercise Intervention ◽  
Risk Profile ◽  
Control Group ◽  
Metabolic Risk ◽  
Model Assessment ◽  
Supervised Exercise

244 Background: Current literature suggests that weight gain during treatment for breast cancer is associated with a poorer prognosis and an increased risk of developing secondary health problems such as the metabolic syndrome (MetSyn). Physical activity (PA) can alter features of the MetSyn and improve body composition by reducing abdominal adiposity. We report metabolic results of a prospective randomized controlled trial (PEACH trial; Walsh JM, et al. [2010] BMC Cancer. 10[42]) which examines the effect of an exercise intervention on the metabolic risk profile of breast cancer survivors 2-6 months post chemotherapy. Methods: All subjects gave written informed consent and were randomized to an 8-week, twice weekly aerobic exercise intervention programme or a usual care control group consisting of routine medical advice about PA. The five clinical features of the MetSyn were measured: waist circumference (WC), resting blood pressure (BP), triglycerides, high-density lipoprotein cholesterol (HDL-C) and fasting glucose. Insulin resistance was estimated by the homeostatic model assessment (HOMA). Statistical analysis was carried out using independent sample t-tests with significance set at p < 0.05. Results: Twenty-six breast cancer survivors participated (mean (± SD) age 48.13 (8.75) years). At baseline, 50% (n = 13) of subjects were overweight and 23.1% (n = 6) were obese, with 73.1% (n = 19) centrally obese. 34.6% (n = 9) of subjects were classified with the MetSyn. There were no significant differences between groups at baseline. Intention-to-treat analysis showed no significant changes, however, analysis of those who adhered to > 70% of the supervised exercise intervention showed a significant improvement in WC when compared to the control group (p < 0.05). Conclusions: Results show that an 8-week aerobic exercise intervention significantly reduced WC but did not modify other features of the MetSyn. The decrease in WC demonstrated by this short intervention may have important implications in terms of improving survival and the metabolic risk profile of breast cancer survivors. Final follow-up assessments are ongoing and will enable change in WC over time to be evaluated further.

scholarly journals OR-052 Effects of Exercise Intervention on Cancer-Related Fatigue in Breast Cancer Survivors

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Zhiling Xie ◽  
Weibing Ye
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Aerobic Exercise ◽  
Breast Cancer Survivors ◽  
Exercise Intervention ◽  
Moderate Intensity ◽  
Control Group ◽  
Short Term ◽  
Cancer Related Fatigue ◽  
Significant Difference

Objective cancer-related fatigue(CRF) is the most commonly reported and most distressing symptom in cancer patient.The purpose of this study was to review the effect of exercise intervention on cancer-related fatigue in breast cancer survivors. Methods From 1998 to 2018 in Chinese and English literature of Wanfang Database, Pubmed, SportDiscus and Springer databases, picked out the randomized controlled trials which up to standard. Keywords cancer, exercise, fatigue, etc. were used for systematic search and tracking. 12 experiments were reviewed to analyze the effect differences between exercise intervention and exercise-related fatigue. Results Most interventions use aerobic exercise as the primary form of exercise. Generally, exercise interventions are effective for cancer-related fatigue, but some findings are not. Many studies have shown that moderate intensity aerobic exercise has a significant effect on cancer-related fatigue, with 50-70% heart rate reserve and 3-5 times of exercise per week for at least 30 minutes each time. Exercise methods mainly include walking, yoga, cycling and tai chi. Firstly, Supervised aerobic exercise was statistically more effective than conventional care in improving CRF among breast cancer survivors. It has been shown that group-based, supervised exercise produces positive psychosocial‘side-effects’ due to social interactions, improved self-efficacy, and attention from a trainer. Secondly, Cancer fatigue is divided into acute and chronic fatigue, 18 weeks of exercise intervention can reduce the short-term fatigue, at 36 weeks, baseline levels of fatigue index responses and contrast on the issue of the multivariate statistics. Thirdly, usual-care group were reported that they had been actively engaged in regular exercise before study enrollment. During the exercise intervention, most studies on the control ways are according to the daily life or to take care of, but studies have reported, before intervention, to a high level of 40% in the control group often exercise, exercise also as usual during the intervention, which causes the control to the baseline level is higher, but the intervention group and control group will be difference, no significant difference, lead to the result is invalid. Conclusions First, the exercise intervention of cancer-related fatigue needs to be supervised; second, the exercise intervention is effective for short-term cancer-related fatigue; third, the daily exercise level of the control group will affect the intervention effect.

EFFECT OF AEROBIC EXERCISE INTERVENTION ON AEROBIC CAPACITY FOR PARKINSON'S PATIENTS 187

1997 ◽  
Vol 29 (Supplement) ◽  
pp. 33
Author(s):  
J. L. Bergen ◽  
T. Toole ◽  
B. Wallace ◽  
K. Robinson ◽  
C. G. Maitland
Keyword(s):  
Aerobic Exercise ◽  
Aerobic Capacity ◽  
Exercise Intervention
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