scholarly journals Circulating Leptin: A Marker of Health in Female Students

2002 ◽  
Vol 30 (2) ◽  
pp. 109-115 ◽  
Author(s):  
T Kondo ◽  
A Yoshida ◽  
R Okada ◽  
T Kanda ◽  
I Kobayashi ◽  
...  

We studied the relationship between serum leptin concentration and lifestyle factors in female nursing students. Serum leptin was estimated by radioimmunoassay and the correlation between these concentrations with serum lipids, physical fitness and Health-promoting Lifestyle Profile score was investigated. A total of 247 students took part in the study: mean age, 19.0 ± 2.0 years; mean body mass index (BMI), 21.7 ± 2.9 kg/m2; and mean serum leptin concentration, 10.8 ± 11.5 ng/ml. Serum leptin was positively correlated with BMI, systolic and diastolic blood pressure, total cholesterol and serum triglyceride. Serum leptin level concentration inversely correlated with physical fitness score and lifestyle score. When the subjects were grouped according to BMI, the high-BMI group (BMI: ≥ 24 kg/m2; n = 40) showed significantly lower fitness and lifestyle scores than the low-BMI group (BMI ≤ 20 kg/m2; n = 70). Higher leptin, blood pressure, total cholesterol and triglyceride were seen in high-BMI compared with low-BMI subjects. We suggest that leptin is a useful marker for monitoring good health and may be useful as a motivational aid towards achieving and maintaining a healthy lifestyle.

2019 ◽  
Vol 19 (1) ◽  
pp. 177-183
Author(s):  
Aung Myo Oo ◽  
Al-abed Ali A. Al-abed ◽  
Ohn MarLwin ◽  
Sowmya Sham Kanneppady ◽  
Sham Kishor Kanneppady

Obesity is one of the most common, yet among the most neglected, public health problems around the world and it is strongly associated with various non-communicable diseases such as hypertension, diabetes mellitus and coronary artery diseases. Health care personal especially nurses play an important role in educating public to have healthy lifestyle. However, there is an alarming rate of increase in number of obesity among nursing students as well as staff nurses. Therefore, the aim of this study was to determine the anthropometric measurements and its associated risks among post-basic renal care nursing students. Total of 142 post-basic renal care nursing students of five intakes were included in this cross-sectional study. The result of the study showed that 52% of participants were either overweight or obese although most of them were below 40 years of age. Majority of overweight or obese students were Malays and 78% of them being female. We also observed an association of systolic blood pressure (SBP), diastolic blood pressure (DBP) and waist circumference (WC)with increasing body mass index (BMI) (P= 0.001, P= 0.001 and P<0.001) which were statistically significant. Wald criterion estimated that WC and DBP were the most important predictors of BMI in present study. Our study concluded that obesity is prevalent among post-basic renal care nursing students. Urgent and appropriate action should be taken to deter the growing problem of obesity among nursing students and to avoid its subsequent complications in Malaysia.


2016 ◽  
Vol 46 (1) ◽  
pp. 13-19
Author(s):  
Michael Fulks ◽  
Vera F. Dolan ◽  
Robert L. Stout

Objective Determine the impact of build on insurance applicant mortality accounting for smoking, laboratory test values and blood pressure. Method The study consisted of 2,051,370 applicants tested at Clinical Reference Laboratory between 1993 and 2007 with build and cotinine measurements available whose body mass index (BMI) was between 15 and 47. Vital status was determined as of September, 2011 by the Social Security Death Master File. Excluded from the primary study were applicants with HbA1c values ≥6.5%, systolic BP ≥141 mmHg, albumin values ≤3.3 g/dL or total cholesterol values ≤130 mg/dL. Relative mortality was determined by Cox regression analysis for bands of BMI split by age, sex and smoking status (urine cotinine positive). Results A majority of applicants had BMI &gt;24 (overweight or obese by WHO criteria). After the exclusions noted above, relative mortality does not increase by &gt;34% unless BMI is &lt;20 (&lt;18 for female non-smokers age 18 to 59) or BMI is &gt;34. BMI values in the range of 22 to 24 and 25 to 29, overall, had similar and the lowest relative risks. For most nonsmokers, risk was lowest in the lower of these two BMI bands but for smokers (and non-smoking males age 60 to 89) risk was lowest in the higher BMI band. Additional analysis showed limited reduction in relative risk by accounting for all laboratory test values as well as continuing the exclusions. Eliminating the exclusions resulted in only a modest increase in relative risk because the mortality rate of the reference band increased as well. Conclusion After excluding elevated HbA1c and blood pressure (associated with high BMI) and low albumin and cholesterol (associated with low BMI) which are usually evaluated separately, mortality varies by a limited degree for BMI 20 to 34. Accounting for the mortality impact of other test values, in addition to the exclusions noted, reduced mortality associated with high BMI to a limited extent, but had little impact on mortality associated with low BMI.


2019 ◽  
Vol 7 (1) ◽  
pp. 35-39
Author(s):  
Nahid Yeasmin ◽  
Qazi Shamima Akhter ◽  
Sayeeda Mahmuda ◽  
Sharmin Nahar ◽  
Mahmuda Abira ◽  
...  

Hyperlipidemia is one of the most widespread medical disorder in female and its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and peripheral vascular diseases. An association between hyperlipidemia and hypertension has been identified. The study was carried out to observe the association of serum triglycerides and total cholesterol level with hypertension in adult female subjects. This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of sixty female subjects were selected with age ranging from 30 to 50 years. Among them 30 female subjects with hypertension were included from the out-patient department of Medicine, Dhaka Medical College Hospital, Dhaka as study group (B) and 30 apparently healthy females were taken as control group (A) for comparison. Estimation of fasting serum triglycerides (TG) and total cholesterol (TC) levels were done by enzymatic method in the Department of Physiology, Dhaka Medical College Dhaka in both groups. Systolic blood pressure and diastolic blood pressure of all participants were recorded by standard method. Data were analyzed by Unpaired Student’s- test and Pearson's correlation co-efficient (r) test as applicable. The values of fasting serum TG level were significantly higher in subjects with hypertension than those of control. Fasting serum TC level was significantly higher in subjects with hypertension in comparison to controls also. In subjects with hypertension fasting serum TG and fasting serum TC levels were higher and showed positive correlation with systolic and diastolic blood pressure. Present study revealed that systolic and diastolic blood pressure has positive relationship with fasting serum triglyceride (TG) and fasting serum cholesterol (TC) levels. Bangladesh Crit Care J March 2019; 7(1): 35-39


Author(s):  
Akram Kooshki ◽  
Mahmood Rivandi ◽  
Mohammad Reza Behroozikhah ◽  
Roya Akbarzadeh

Background: Hypertension is the third risk factor for the cardiovascular diseases. This study investigated the effects of mineral water from Damavand spring on the blood pressure and serum lipid profiles in men with hypertension. Methods: In this study 41 hypertensive men were randomly assigned to Damavand mineral water (DM) and Tehran water groups (TW). The DM and TW received 1.5-liter bottle of mineral water of Damavand spring and Tehran piped water bottled, respectively. The participants' blood pressure, serum triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDLc), and high-density lipoprotein cholesterol (HDLc) were measured at the beginning and end of the study. Total hardness of water was measured by titration with EDTA. Results: The results showed that the mean systolic and diastolic blood pressures decreased in both groups at the end of the study compared to the baseline (P < 0.05), but the difference was not significant. Serum TC and LDLc significantly in the case group at the end of week 8 compared to the baseline (P < 0.05) and this reduction was significant (P < 0.05). Moreover, no significant differences were observed between the two groups with regard to the mean changes of TG and HDLc (P > 0.05). Conclusions: The findings showed that the daily consumption of 1.5 liters of premium mineral water of Damavand springs decreased the systolic and diastolic blood pressure, total cholesterol, and LDLc levels.


Author(s):  
В.Д. Прошляков ◽  
П.В. Левин ◽  
В.М. Ериков

В статье раскрыты пути реализации национального проекта № 1 «Демография» (паспорт был утвержден 24 декабря 2018 года), основными целями которого являются увеличение ожидаемой продолжительности здоровой жизни до 67 лет, а также доли граждан, ведущих здоровый образ жизни. Представлена попытка анализа текущего состояния здоровья учащейся молодежи с целью дальнейшей выработки конструктивных решений по реализации данного проекта. Обращено внимание на актуальные проблемы современного общества — ежегодный рост заболеваемости школьников, неудовлетворительную деятельность школьной медицины, низкий уровень физической подготовленности выпускников школ, что приводит к ухудшению здоровья молодежи в целом, снижению рождаемости в России и является реальной угрозой национальной безопасности страны. Описаны направления работы, необходимые, по мнению авторов, для оптимизации и улучшения системы школьного физического воспитания детей и подростков, а также предполагающие повышение ответственности системы образования за здоровье обучающихся в соответствии с Федеральным законом «Об образовании в Российской Федерации». Сегодня становится необходимым усиление внимания к вопросам школьной медицины в совокупности с оптимизацией двигательного режима школьников. Важно также проводить занятия физической культурой в учебной и внеучебной форме и развивать общую выносливость, лежащую в основе оптимального функционирования главных физиологических систем организма; сохранять и укреплять здоровье школьников в процессе обучения в школе основам здорового образа жизни, включающего здоровое питание и отказ от вредных привычек; создавать ведомственную медицинскую службу в системе образования с целью формирования полноценной школьной медицины. The article discusses some ways of implementing the Demography Project (Federal project no. 1 of December 24, 2018) whose main aims are the increase of healthy life expectancy to 67 years and the enlargement of the number of citizens leading a healthy life style. The article makes an attempt to analyze learners’ health to further elaborate some efficient solutions aimed at the implementation of the project. The article highlights some urgent problems ailing modern society, such as annual increase of morbidity rates among children, unsatisfactory quality of school medicine, the low level of school leavers’ physical fitness. All this leads to a continuous decline in schoolchildren’s health, provokes a decrease of birth rates, and presents a serious threat to national security. The article focuses on what can be done to optimize and improve the system of physical education in schools, to ensure that in accordance with the federal law On Education in the Russian Federation, schools should be held responsible for securing children’s and adolescents’ health and physical fitness. Nowadays, it is obvious that the issues of school medicine as well as the optimization of schoolchildren’s motor activities should be given proper attention, It is essential that there should be curriculum and extra-curriculum physical activities aimed at improving children’s stamina and cardio endurance, which is an essential prerequisite for the maintenance of good health. It is essential that school health services should fully contribute to the goals of both the system of education and healthcare system. It is essential that schools should do everything possible to improve children’s and adolescents’ health, to ensure that children and adolescents lead a healthy lifestyle, eat healthy food, have no bad habits.


Author(s):  
Volkan Aydin ◽  
Caner Vizdiklar ◽  
Ahmet Akici ◽  
Mehmet Akman ◽  
Dilek Gogas Yavuz ◽  
...  

Abstract Aim: To determine the presence of cardiovascular (CV) risk (CVR) factors in university students and evaluate how these factors are affected from the knowledge, attitudes, and habits of the individuals regarding healthy lifestyle. Background: Starting from early ages, lifestyle habits such as lack of physical activity, unhealthy eating, and inappropriate drug use increase CV and metabolic risks of individuals. Methods: In April–May 2018, sociodemographic characteristics of 770 undergraduate students, in addition to their knowledge, attitudes, and habits regarding their nutrition and physical activity status were obtained through face-to-face questionnaires. CVR factors were determined according to blood pressure, blood glucose, total cholesterol levels, and anthropometric measurements. Collected data were compared by CVR factor presence (CV[+] or CV[−]) in students. Findings: The mean age of the participants was 22.3 ± 2.6 years. 59.6% were female and 71.5% were students of non-health sciences. In total, 274 individuals (35.9%) belonged to CV(+) group (mean risk number: 1.3 ± 0.5) with higher frequency in males (42.1% versus 31.6%, P < 0.05). The most common CVR factors were smoking (20.6%), high total cholesterol (7.5%), and hypertension/high blood pressure (6.0%). 15.5% of the participants regularly used at least one drug/non-pharmaceutical product. 11.3% complied the Mediterranean diet well. 21.9% of CV(+) stated consuming fast food at lunch compared to 14.3% of CV(−) (P < 0.05). 44.6% stated exercising below the CV-protective level. Conclusions: This study showed one-third of university students was at CVR, independent of their sociodemographic characteristics. Furthermore, the students appear to perform below expectations in terms of nutrition and physical activity. Extensive additional measures are needed to encourage young individuals for healthy nutritional and physical activity habits.


Author(s):  
Manuel Chavarrias ◽  
Jorge Carlos-Vivas ◽  
Beatriz Barrantes-Martín ◽  
Jorge Pérez-Gómez

2019 ◽  
Vol 14 (5) ◽  
pp. 376-385 ◽  
Author(s):  
Lin Xu ◽  
Jiangming Huang ◽  
Zhe Zhang ◽  
Jian Qiu ◽  
Yan Guo ◽  
...  

Objective: The purpose of this study was to establish whether Triglycerides (TGs) are related to Blood Pressure (BP) variability and whether controlling TG levels leads to better BP variability management and prevents Cardiovascular Disease (CVD). Methods: In this study, we enrolled 106 hypertensive patients and 80 non-hypertensive patients. Pearson correlation and partial correlation analyses were used to define the relationships between TG levels and BP variability in all subjects. Patients with hypertension were divided into two subgroups according to TG level: Group A (TG<1.7 mmol/L) and Group B (TG>=1.7 mmol/L). The heterogeneity between the two subgroups was compared using t tests and covariance analysis. Results: TG levels and BP variability were significantly different between the hypertensive and non-hypertensive patients. Two-tailed Pearson correlation tests showed that TG levels are positively associated with many BP variability measures in all subjects. After reducing other confounding factors, the partial correlation analysis revealed that TG levels are still related to the Standard Deviation (SD), Coefficient of Variation (CV) of nighttime systolic blood pressure and CV of nighttime diastolic blood pressure, respectively (each p<0.05). In the subgroups, group A had a lower SD of nighttime Systolic Blood Pressure (SBP_night_SD; 11.39±3.80 and 13.39±4.16, p=0.011), CV of nighttime systolic blood pressure (SBP_night_CV; 0.09±0.03 and 0.11±0.03, p=0.014) and average real variability of nighttime systolic blood pressure (SBP_night_ARV; 10.99±3.98 and 12.6±3.95, p=0.024) compared with group B, even after adjusting for age and other lipid indicators. Conclusion: TG levels are significantly associated with BP variability and hypertriglyceridemia, which affects blood pressure variability before causing target organ damage.


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