Frequent, short bouts of light-intensity exercises while standing decreases systolic blood pressure: Breaking Up Sitting Time after Stroke (BUST-Stroke) trial

2018 ◽  
Vol 13 (9) ◽  
pp. 932-940 ◽  
Author(s):  
Coralie English ◽  
Heidi Janssen ◽  
Gary Crowfoot ◽  
Josephine Bourne ◽  
Robin Callister ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Light Intensity ◽  
Systolic Blood Pressure ◽  
Plasma Fibrinogen ◽  
Sitting Time ◽  
Stroke Survivors ◽  
Clotting Factors ◽  
Increased Risk ◽  
Intensity Physical Activity

Background Stroke survivors sit for long periods each day. Uninterrupted sitting is associated with increased risk of cardiovascular disease. Breaking up uninterrupted sitting with frequent, short bouts of light-intensity physical activity has an immediate positive effect on blood pressure and plasma clotting factors in healthy, overweight, and type 2 diabetic populations. Aim We examined the effect of frequent, short bouts of light-intensity physical activity on blood pressure and plasma fibrinogen in stroke survivors. Methods Prespecified secondary analyses from a three-armed randomized, within-participant, crossover trial. Participants were 19 stroke survivors (nine female, aged 68 years old, 90% able to walk independently). The experimental conditions were sitting for 8 h uninterrupted, sitting with 3 min bouts of light-intensity exercise while standing every 30 min, or sitting with 3 min of walking every 30 min. Blood pressure was measured every 30 min over 8 h and plasma fibrinogen at the beginning, middle, and end of each day. Intention-to-treat analyses were performed using linear mixed models including fixed effects for condition, period, and order, and a random intercept for participant to account for repeated measures and missing data. Results Sitting with 3 min bouts of light-intensity exercise while standing every 30 min decreased systolic blood pressure by 3.5 mmHg (95% CI 1.7–5.4) compared with sitting for 8 h uninterrupted. For participants not taking antihypertensive medications, sitting with 3 min of walking every 30 min decreased systolic blood pressure by 5.0 mmHg (95% CI −7.9 to 2.0) and sitting with 3 min bouts light-intensity exercise while standing every 30 min decreased systolic blood pressure by 4.2 mmHg (95% CI −7.2 to −1.3) compared with sitting for 8 h uninterrupted. There was no effect of condition on diastolic blood pressure (p = 0.45) or plasma fibrinogen levels (p = 0.91). Conclusion Frequent, short bouts of light-intensity physical activity decreases systolic blood pressure in stroke survivors. However, before translation into clinical practice, the optimal duration and timing of physical activity bouts needs to be determined. Clinical trial registration Australian and New Zealand Clinical Trials Registry http://www.anzctr.org.au ANZTR12615001189516.

Breaking up sitting time after stroke (BUST-stroke)

2018 ◽  
Vol 13 (9) ◽  
pp. 921-931 ◽  
Author(s):  
Coralie English ◽  
Heidi Janssen ◽  
Gary Crowfoot ◽  
Robin Callister ◽  
Ashlee Dunn ◽  
...  
Keyword(s):  
Physical Activity ◽  
Glucose Metabolism ◽  
Light Intensity ◽  
Plasma Glucose ◽  
Recurrent Stroke ◽  
Blood Glucose Control ◽  
Random Order ◽  
Sitting Time ◽  
Experimental Conditions ◽  
Intensity Physical Activity

Objectives People with stroke sit for long periods each day, which may compromise blood glucose control and increase risk of recurrent stroke. Studies in other populations have found regular activity breaks have a significant immediate (within-day) positive effect on glucose metabolism. We examined the effects of breaking up uninterrupted sitting with frequent, short bouts of light-intensity physical activity in people with stroke on post-prandial plasma glucose and insulin. Methods Randomized within-participant crossover trial. We included people between 3 months and 10 years post-stroke, ambulant with minimal assistance and not taking diabetic medication other than metformin. The three experimental conditions (completed in random order) were: sitting for 8 h uninterrupted, sitting with 3 min bouts of light-intensity exercise while standing every 30 min, or sitting with 3 min of walking every 30 min. Meals were standardized and bloods were collected half- to one-hourly via an intravenous cannula. Results A total of 19 participants (9 female, mean [SD] age 68.2 [10.2]) completed the trial. The majority ( n = 12, 63%) had mild stroke symptoms (National Institutes of Stroke Scale score 0–13). There was no significant effect of experimental condition on glucose (mean [SD] positive incremental area [+iAUC] mmol·L·h-1 under the curve during sitting 42.3 [29.5], standing 47.4 [23.1], walking 44.6 [26.5], p = 0.563) or insulin (mean + iAUC pmol·L·h-1 sitting 14,161 [7,560], standing 14,043 [8,312], walking 14,008 [8,269], p = 0.987). Conclusion Frequent, short bouts of light-intensity physical activity did not have a significant effect on post-prandial plasma glucose and insulin in this sample of people with stroke. Further studies are needed to identify strategies that improve inactivity-related glucose metabolism after stroke.

Light-Intensity Physical Activity and Cardiometabolic Risk Among Older Adults With Multiple Chronic Conditions

2018 ◽  
Vol 33 (4) ◽  
pp. 507-515 ◽  
Author(s):  
Yueyao Li ◽  
Kellee White ◽  
Katherine R. O’Shields ◽  
Alexander C. McLain ◽  
Anwar T. Merchant
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Older Adults ◽  
Light Intensity ◽  
Total Cholesterol ◽  
Chronic Conditions ◽  
Cardiometabolic Risk ◽  
Multiple Chronic Conditions ◽  
Intensity Physical Activity

Purpose: To assess the relationship between light-intensity physical activity (LIPA) and cardiometabolic risk factors among middle-aged and older adults with multiple chronic conditions. Design: Cross-sectional design utilizing data from the Health and Retirement Study (2010, 2012). Setting: Laboratory- and survey-based testing of a nationally representative sample of community-dwelling middle aged and older adults. Participants: Adults aged 50 years and older (N = 14 996). Measures: Weighted metabolic equivalent of tasks was calculated using self-reported frequency of light, moderate, and vigorous physical activity. Cardiometabolic risk factors (systolic and diastolic blood pressure, glycosylated hemoglobin [HbA1c], high-density lipoprotein cholesterol [HDL-C], total cholesterol, and non-HDL-C) were objectively measured. A multiple chronic condition index was based on 8 self-reported chronic conditions. Analysis: Weighted multivariate linear regression models. Results: Light-intensity physical activity was independently associated with favorable HDL-C (β = 1.25; 95% confidence interval [CI]: 0.46-2.05) and total cholesterol (β = 2.72; 95% CI: 0.53-4.90) after adjusting for relevant confounders. The HDL-C health benefit was apparent when stratified by number of chronic conditions, for individuals with 2 to 3 conditions (β = 1.73; 95% CI: 0.58-2.89). No significant associations were observed between LIPA and blood pressure, HbA1c, or non-HDL-C. Conclusions: Engaging in LIPA may be an important health promotion activity to manage HDL-C and total cholesterol. Additional longitudinal research is needed to determine the causal association between LIPA and cardiometabolic risk which can potentially inform physical activity guidelines targeting older adults with multiple chronic conditions.

Walking Workstation Use Reduces Ambulatory Blood Pressure in Adults with Prehypertension

2015 ◽  
Vol 12 (s1) ◽  
pp. S119-S127 ◽  
Author(s):  
Zachary S. Zeigler ◽  
Pamela D. Swan ◽  
Dharini M. Bhammar ◽  
Glenn A. Gaesser
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Light Intensity ◽  
Ambulatory Blood Pressure ◽  
Acute Effect ◽  
Men And Women ◽  
Low Intensity ◽  
Intensity Physical Activity ◽  
Pm 10

Background:The acute effect of low-intensity walking on blood pressure (BP) is unclear.Purpose:To determine if the acute use of a walking workstation reduces ambulatory blood pressure (ABP) in prehypertensive men and women.Methods:Ten prehypertensive adults participated in a randomized, cross-over study that included a control workday and a walking workstation workday. ABP was measured for 7 hour during the workday and for 6 hour after work.Results:Both systolic BP (SBP) (134 ± 14 vs. 137 ± 16 mmHg; P = .027) and diastolic BP (DBP) (79 ± 10 vs. 82 ± 12 mmHg; P = .001) were lower on the walking workstation day. Postwork hours (4:00 PM–10:00 PM), SBP (129 ± 13 vs. 133 ± 14 mmHg; P = .008), and DBP (74 ± 11 vs. 78 ± 13 mmHg; P = .001) were also lower on the walking workstation day. DBP load was significantly lower during the walking workstation day, with only 14% of the readings above 90 mmHg compared with 22% of the control day readings (P = .037).Conclusion:Accumulation of very-light-intensity physical activity (~2 METs) over the course of a single work day using a walking workstation may reduce BP burden in prehypertensive individuals.

scholarly journals Higher levels of physical activity is associated with lower arterial stiffness in patients with resistant hypertension

2021 ◽  
Vol 20 (Supplement_1) ◽  
Author(s):  
S Lopes ◽  
J Mesquita-Bastos ◽  
C Garcia ◽  
C Leitao ◽  
S Bertoquini ◽  
...  
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Arterial Stiffness ◽  
Resistant Hypertension ◽  
Target Organ Damage ◽  
Daily Physical Activity ◽  
Development Fund ◽  
Cardiovascular Morbidity And Mortality ◽  
Increased Risk ◽  
Intensity Physical Activity

Abstract Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Portuguese Foundation for Science and Technology (FCT) European Regional Development Fund – Operational Competitiveness Factors Program (COMPETE) Background  Physical activity has been associated with reduced arterial stiffness in patients with hypertension. However, in resistant hypertension, a specific population with an increased risk for target organ damage, cardiovascular morbidity, and mortality, the evidence is sparse.  Purpose  The present study aimed to determine the association between daily physical activity and arterial stiffness in patients with resistant hypertension. Methods  Fifty-seven patients with resistant hypertension were recruited. Physical activity was objectively assessed during 7 consecutive days with accelerometers. Arterial stiffness was evaluated using carotid-femoral pulse wave velocity (cf-PWV) .  Results  Participants (50.9% men), aged 58.8 ± 9.4 years, were mainly overweight and were taking in average 4.5 antihypertensive medications. The cf-PWV showed an inverse correlation with light-intensity physical activity (r = -0.290, p = 0.029) and total daily physical activity (r = -0.287, p = 0.030). Additionally, cf-PWV tended to be inversely associated with the number of steps per day (r = -0.242, p = 0.069). Patients with higher risk of cardiovascular events (cf-PWV ≥ 10 m/s) tended to spend less time in light-intensity physical activity (324.0 ± 129.4 vs. 380.5 ± 103.1 min/day, p = 0.090) and to perform less total daily physical activity (351.5 ± 141.7 vs. 411.7 ± 109.1 min/day, p = 0.091) than participants with cf-PWV below the risk threshold value. Conclusions  Higher levels of total physical activity and daily levels of light-intensity were associated to lower arterial stiffness. These results emphasize the importance of physical activity as a nonpharmacological tool for patients with resistant hypertension.

scholarly journals Efectos de un programa de actividad física vigorosa en la tensión arterial y frecuencia cardiaca de escolares de 8-9 años

2019 ◽  
Vol 8 (1) ◽  
pp. 73-80
Author(s):  
G. F. López Sánchez ◽  
E. J. Ibáñez Ortega ◽  
A. Díaz Suárez
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
School Children ◽  
Cardiovascular Health ◽  
Physical Activity Program ◽  
Activity Program ◽  
Post Test ◽  
Intensity Physical Activity

En la actualidad, las investigaciones encaminadas a mejorar la salud cardiovascular de las personas son de suma importancia. Objetivo: Este artículo se centra en estudiar los efectos de un programa de actividad física sobre la tensión arterial (TA) y frecuencia cardiaca (FC) de un grupo de escolares. Métodos: Participaron 41 escolares (19 niños y 22 niñas), entre los 8 y los 9 años de edad (media de edad 8,49 y DE 0,51). Las variables estudiadas fueron: tensión arterial (sistólica y diastólica) y frecuencia cardiaca en reposo. La tensión arterial y la frecuencia cardiaca se midieron con el tensiómetro de brazo Visomat Comfort 20/40. El procedimiento ha sido: pre-test, intervención y pos-test. La intervención ha consistido en 3 días a la semana de actividad física de alta intensidad, 15 minutos al día, durante 12 semanas. Resultados: Se ha realizado un análisis de datos por medio del SPSS 22 y se han obtenido mejoras significativas en la tensión arterial sistólica y la frecuencia cardiaca (Sig. p < 0.05). Conclusiones: El programa de actividad física empleado en este estudio puede ser de utilidad para mejorar la tensión arterial sistólica y la frecuencia cardiaca de escolares de 8-9 años. Nowadays, research aimed at improving the cardiovascular health of people is of the utmost importance. Objective: This paper focuses on studying the effects of a vigorous-intensity physical activity program on the blood pressure (BP) and heart rate (HR) of a group of school children. Methods: This investigation involved 41 children (19 boys and 22 girls), aged between 8 and 9 years (average age=8.49 and standard deviation=0.51). The variables considered were: blood pressure (systolic and diastolic) and resting heart rate. Blood pressure and heart rate were measured by arm sphygmomanometer Visomat Comfort 20/40. The procedure was as follows: pre-test, intervention and post-test. The intervention consisted of 3 days per week of high-intensity physical activity, 15 minutes per day, during 12 weeks. Results: Data analysis was performed through SPSS 22 and significant improvements were obtained in systolic blood pressure and heart rate (Sig p < 0.05). Conclusions: The physical activity program implemented in this study may be useful to improve systolic blood pressure and heart rate in 8- and 9-year-old school children.

scholarly journals The Effects of Interrupting Prolonged Sitting With Frequent Bouts of Light-Intensity Standing Exercises on Blood Pressure in Stroke Survivors: A Dose Escalation Trial

2021 ◽  
pp. 1-10
Author(s):  
Paul Mackie ◽  
Gary Crowfoot ◽  
Heidi Janssen ◽  
Elizabeth Holliday ◽  
David Dunstan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Light Intensity ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Dose Escalation ◽  
Reduce Blood Pressure ◽  
Stroke Survivors ◽  
Experimental Conditions ◽  
Prolonged Sitting ◽  
The Mean

Background: Interrupting prolonged sitting acutely lowers blood pressure in nonstroke populations. However, the dose–response effect in stroke survivors is unknown. The authors investigated different doses of light-intensity standing exercises that interrupt prolonged sitting and reduce blood pressure immediately and over 24 hours in stroke survivors. Methods: Within-participant, laboratory-based, dose escalation trial. Conditions (8 h) were prolonged sitting and 2 experimental conditions of standing exercises with increasing frequency (3 cohorts, 2 × 5 min to 6 × 5 min). The primary outcome is the mean systolic blood pressure. Results: Twenty-nine stroke survivors (aged 66 [12] y) participated. Frequent bouts of standing exercises lowered the mean systolic blood pressure following the 4 × 5-minute (−2.1 mm Hg; 95% confidence interval [CI], −3.6 to −0.6) and 6 × 5-minute conditions (−2.3 mm Hg; 95% CI, −4.2 to −0.5) compared with prolonged sitting. Diastolic blood pressure was lowered following the 6 × 5-minute condition (−1.4 mm Hg; 95% CI, −2.7 to −0.2). The 24-hour systolic blood pressure increased following the 2 × 5-minute condition (6.9 mm Hg; 95% CI, 3.1 to 10.6). Conclusions: Interrupting prolonged sitting with more frequent bouts of standing exercises lowers systolic and diastolic blood pressure in stroke survivors. However, reductions may only be short term, and investigations on sustained effects are warranted.

scholarly journals High-intensity activity is more strongly associated with metabolic health in children compared to sedentary time: a cross-sectional study of the I.Family cohort

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jonatan Fridolfsson ◽  
Christoph Buck ◽  
Monica Hunsberger ◽  
Joanna Baran ◽  
Fabio Lauria ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Body Mass Index ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Cross Sectional ◽  
Intensity Physical Activity

Abstract Background Physical activity (PA) during childhood is important for preventing future metabolic syndrome (MetS). To examine the relationship between PA and MetS in more detail, accurate measures of PA are needed. Previous studies have only utilized a small part of the information available from accelerometer measured PA. This study investigated the association between measured PA and MetS in children with a new method for data processing and analyses that enable more detailed interpretation of PA intensity level. Methods The association between PA pattern and risk factors related to MetS was investigated in a cross- sectional sample of children (n = 2592, mean age 10.9 years, 49.4% male) participating in the European multicenter I. Family study. The risk factors examined include body mass index, blood pressure, high-density lipoprotein cholesterol, insulin resistance and a combined risk factor score (MetS score). PA was measured by triaxial accelerometers and raw data was processed using the 10 Hz frequency extended method (FEM). The PA output was divided into an intensity spectrum and the association with MetS risk factors was analyzed by partial least squares regression. Results PA patterns differed between the European countries investigated, with Swedish children being most active and Italian children least active. Moderate intensity physical activity was associated with lower insulin resistance (R2 = 2.8%), while vigorous intensity physical activity was associated with lower body mass index (R2 = 3.6%), MetS score (R2 = 3.1%) and higher high-density lipoprotein cholesterol (R2 = 2.3%). PA of all intensities was associated with lower systolic- and diastolic blood pressure, although the associations were weaker than for the other risk factors (R2 = 1.5% and R2 = 1.4%). However, the multivariate analysis implies that the entire PA pattern must be considered. The main difference in PA was observed between normal weight and overweight children. Conclusions The present study suggests a greater importance of more PA corresponding to an intensity of at least brisk walking with inclusion of high-intense exercise, rather than a limited time spent sedentary, in the association to metabolic health in children. The methods of data processing and statistical analysis enabled accurate analysis and interpretation of the health benefits of high intensity PA that have not been shown previously.

Long term habitual vigorous physical activity is associated with lower visit-to-visit systolic blood pressure variability

2020 ◽  
Author(s):  
Xiaoyong Xu ◽  
Xianghong Meng ◽  
Shin-ichi Oka
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Standard Deviation ◽  
Systolic Blood Pressure ◽  
Blood Pressure Variability ◽  
Vigorous Physical Activity ◽  
Systolic Blood Pressure Variability ◽  
Average Real Variability ◽  
Post Hoc

Abstract Objective Our work aimed to investigate the association between vigorous physical activity and visit-to-visit systolic blood pressure variability (BPV). Methods We conducted a post hoc analysis of SPRINT (Systolic Blood Pressure Intervention Trial), a well-characterized cohort of participants randomized to intensive (&lt;120 mmHg) or standard (&lt;140 mmHg) SBP targets. We assessed whether patients with hypertension who habitually engage in vigorous physical activity would have lower visit-to-visit systolic BPV compared with those who do not engage in vigorous physical activity. Visit-to-visit systolic BPV was calculated by standard deviation (SD), average real variability (ARV), and standard deviation independent of the mean (SDIM) using measurements taken during the 1-, 2-, 3-, 6-, 9- and 12-month study visits. A medical history questionnaire assessed vigorous physical activity, which was divided into three categories according to the frequency of vigorous physical activity. Results A total of 7571 participants were eligible for analysis (34.8% female, mean age 67.9±9.3 years). During a follow-up of 1-year, vigorous physical activity could significantly reduce SD, ARV, and SDIM across increasing frequency of vigorous physical activity. There were negative linear trends between frequency of vigorous physical activity and visit-to-visit systolic BPV. Conclusions Long-term engagement in vigorous physical activity was associated with lower visit-to-visit systolic BPV.

Sign in / Sign up

Export Citation Format

Share Document