scholarly journals Magnoflorine and Phenolic Derivatives from the Leaves of Croton xalapensis L. (Euphorbiaceae)

2009 ◽  
Vol 4 (12) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Carolina Arevalo ◽  
Cinzia Lotti ◽  
Anna Lisa Piccinelli ◽  
Mariateresa Russo ◽  
Ines Ruiz ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Cinnamyl Alcohol ◽  
Dihydroxybenzoic Acid ◽  
High Concentration ◽  
Phytochemical Study ◽  
Medicinal Properties ◽  
Phenolic Derivatives ◽  
First Time ◽  
Quantitative Hplc

The alkaloid magnoflorine 1, has been isolated for the first time from Croton xalapensis (Euphorbiaceae), in addition two phenylpropenols derivates, 3,4-dimethoxy-(E)-cinnamyl alcohol 2 and 3,4-dimethoxy-5-hydroxy-(E)-cinnamyl alcohol 3, 3,4,5-trimethoxycinnamic acid 4, gallic acid 5, methyl gallate 6 and 3,4-dihydroxybenzoic acid 7 have been also found; these compounds were identified by spectroscopic analysis particularly, 2D NMR and ESI-MS/MS techniques. The high concentration of magnoflorine, calculated with quantitative HPLC, of the aqueous extract, probably contributes to the remarkable medicinal properties of this plant. In addition this is the first phytochemical study on Croton xalapensis to be reported.

Limonoids from Aphanamixis polystachya Leaves and Their Interaction with Hsp90

Planta Medica ◽  
2018 ◽  
Vol 84 (12/13) ◽  
pp. 964-970 ◽  
Author(s):  
César Muñoz Camero ◽  
Antonio Vassallo ◽  
Marinella De Leo ◽  
Abeer Temraz ◽  
Nunziatina De Tommasi ◽  
...  
Keyword(s):  
Molecular Chaperone ◽  
Natural Compounds ◽  
Spectroscopic Methods ◽  
Phytochemical Study ◽  
Phenolic Derivatives ◽  
New Compounds ◽  
Type 3 ◽  
First Time

AbstractA phytochemical study of n-hexane, CHCl3, and CHCl3-MeOH extracts of Aphanamixis polystachya leaves led to the isolation of 10 compounds. Five of them turned out to be new natural compounds, including two mexicanolide-type (1, 2) and three polyoxyphragmalin-type (3–5) limonoids, together with two known andirobin-type limonoids (6, 7) and three phenolic derivatives. The structures of the new compounds were established on the basis of spectroscopic methods to be 8-hydro-14,15-en-cabralin (1), 3-deacetyl-8-hydro-cabralin-14,15-en-3-one (2), 20,22-dihydroxy-21,23-dimethoxytetrahydrofuran khayanolide A (3), 1-deacetyl-3-dehydroxy-3-oxokhaysenelide E (4), and meliaphanamixin A (5). All compounds were isolated for the first time from this species. The ability of the isolated limonoids to interact with the molecular chaperone Hsp90 was tested. Compounds 6 and 7 were the most active.

Aspernolides L and M, new butyrolactones from the endophytic fungus Aspergillus versicolor

2017 ◽  
Vol 72 (5-6) ◽  
pp. 155-160 ◽  
Author(s):  
Sabrin R.M. Ibrahim ◽  
Gamal A. Mohamed ◽  
Samir A. Ross
Keyword(s):  
Endophytic Fungi ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Systematic Search ◽  
Aspergillus Versicolor ◽  
Active Compounds ◽  
Etoac Extract ◽  
First Time

Abstract During the systematic search of active compounds from endophytic fungi, two new butyrolactones, namely aspernolides L (2) and M (4), together with four known compounds: 1-O-acetylglycerol (1), butyrolactone I (3), butyrolactone VI (5), and (+) alantrypinone (6) were characterized from the EtOAc extract of the endophytic fungus Aspergillus versicolor isolated from the roots of Pulicaria crispa (Asteraceae). Extensive spectroscopic analysis, including 1D, 2D NMR, and HRESIMS, was used to elucidate their structures. Compounds 1, 5, and 6 are reported for the first time from this fungus.

Chemical constituents of two Ecuadorian medicinal plants, Tagetes terniflora Kunth and Croton rivinifolius Kunth

2021 ◽  
Author(s):  
Alírica I Suárez ◽  
Vladimir Morocho ◽  
Vladimir Luna ◽  
Katty Castillo ◽  
Chabaco Armijos
Keyword(s):  
Medicinal Plants ◽  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
Two Dimensional ◽  
Phytochemical Study ◽  
Isolation And Characterization ◽  
Organic Extracts ◽  
Medicinal Properties ◽  
Nmr Methods

Phytochemical study of two medicinal plants from Ecuador, Tagetes terniflora Kunth, and Croton rivinifolius Kunth, led to the isolation and characterization of the major constituents present in the organic extracts obtained from these plants: 5-(4-acetoxy-1-butynil)-2,2’-bi-thiophene (1), 5-methyl-2,2’:5’,2”- terthiophene (2), patuletin (3) from Tagetes terniflora, and isocorydine (4), sweroside (5), tiliroside (6) from Croton rivinifolius. The structures of these compounds were established by spectroscopic analysis including two-dimensional NMR methods, MS, and comparison with published spectral data. They are recognized as secondary metabolites that represent the chemotaxonomy of Tagetes and Croton genera and could be responsible for the recognized medicinal properties attributed to these species. This paper deals with the first report that shows the presence of these compounds in these plants.

A New Chlorine-containing Glucosyl-fused Compound from Curculigo glabrescens

2009 ◽  
Vol 64 (9) ◽  
pp. 1077-1080 ◽  
Author(s):  
Cui-Cui Zhu ◽  
Tian-Ming Wang ◽  
Kai-Jin Wang ◽  
Ning Li
Keyword(s):  
Spectroscopic Analysis ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
2D Nmr ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Dpph Assay ◽  
Etoh Extract ◽  
Structure Activity ◽  
First Time

A new chlorine-containing glucosyl-fused compound, crassifoside H (1), was isolated from the EtOH extract of the rhizomes of Curculigo glabrescens. The structure was established on the basis of MS, IR, 1D and 2D NMR experiments. In addition, seven known compounds (2 - 8) were isolated and identified by spectroscopic analysis and comparison of their spectral data with those reported previously. All the compounds were isolated from this plant for the first time. The free radical scavenging activity of the isolated compounds was evaluated by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Compounds 1 and 2 showed strong radical scavenging activities. The primary structure-activity relationship is also discussed.

Fast Counter Current Chromatography of n-Butanolic Fraction from Senecio giganteus (Asteraceae)

2009 ◽  
Vol 4 (10) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Nadjet Mezache ◽  
Séverine Derbré ◽  
Salah Akkal ◽  
Hocine Laouer ◽  
Denis Séraphin ◽  
...  
Keyword(s):  
Methyl Ester ◽  
2D Nmr ◽  
Spectrometric Analysis ◽  
Partition Chromatography ◽  
Centrifugal Partition Chromatography ◽  
Phytochemical Composition ◽  
Phenolic Derivatives ◽  
Counter Current ◽  
First Time ◽  
Fast Centrifugal Partition Chromatography

Phenolic derivatives such as quinones, acid-phenols and flavonoids were successfully isolated from a n-butanolic fraction of Senecio giganteus Desf. (Asteraceae) flowers, namely jacaranone (1), 3a-hydroxy-3,3a,7,7a-tetrahydrobenzofuran-2,6-dione (2), chlorogenic acid (3), hyperoside (4), quercetin 3-O-β-D-robinobioside (5), isorhamnetin-3-O-β-D-glucuronide (6), quercetin-3-O-β-D-glucuronide (7), and isorhamnetin-3-O-β-D-glucuronide-6″-methyl ester (8). These compounds were purified through either classical polyamide filtration followed by fractionation on Si gel, or through fast centrifugal partition chromatography (FCPC). Using FCPC, the major compounds could be readily isolated from the crude n-butanolic fraction. Compounds 1-8 were identified by means of spectroscopic and spectrometric analysis (UV, 1H, 13C and 2D NMR, and MS). This work described for the first time the phytochemical composition of this endemic Algerian plant.

MWL fraction with a high concentration of lignin-carbohydrate linkages: Isolation and 2D NMR spectroscopic analysis

Holzforschung ◽  
2007 ◽  
Vol 61 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Mikhail Yu. Balakshin ◽  
Ewellyn A. Capanema ◽  
Hou-min Chang
Keyword(s):  
Loblolly Pine ◽  
Spectroscopic Analysis ◽  
Direct Detection ◽  
2D Nmr ◽  
Side Chain ◽  
High Concentration ◽  
Hmbc Correlation ◽  
Nmr Techniques ◽  
C Nmr ◽  
Hmbc Technique

Abstract A preparation enriched in lignin-carbohydrate fragments (LCC-AcOH) was isolated in the course of purification of loblolly pine crude milled wood lignin (MWL). The preparation contained approximately equal amounts of lignin and carbohydrates, with high amounts of arabinose and galactose compared to their levels in wood. LCC-AcOH was investigated by 2D 1H-13C (HMQC and HMBC) correlation NMR techniques and quantitative 13C NMR. The HMQC spectra allowed direct detection of phenyl glycoside, ester and benzyl ether lignin-carbohydrates linkages in high amounts. The assignment of these structures was supported by the HMBC technique. It is noteworthy that in the ester lignin-carbohydrate linkages, a uronic acid residue was attached not to the benzylic position of lignin, as commonly believed, but to the γ-position of the side chain.

scholarly journals PHENOLIC COMPOUNDS FROM STEM OF BOERHAVIA ERECTA L. GROWING IN VIETNAM

2011 ◽  
Vol 14 (2) ◽  
pp. 58-65
Author(s):  
Lien Thi My Do ◽  
Dung Thi My Nguyen ◽  
Phung Kim Phi Nguyen
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Resistance Protein ◽  
2D Nmr ◽  
Hepatoprotective Activity ◽  
Cancer Resistance ◽  
New Class ◽  
Nmr Data ◽  
Medicinal Properties ◽  
Resistance Protein ◽  
First Time

Plants of Boerhavia genus (Nyctaginaceae family) are known to have medicinal properties as antidiabetic, immunomodulatory effect, anticonvulsant, antistress, adaptogenic, hepatoprotective activity. Rotenoids in plants of this genus are reported as a new class of potent breast cancer resistance protein inhibitors.[5] Boerhavia erecta L. was used in traditional African medicine but there are still no scientific research in Vietnam where it is widely grown. In this paper, we report the isolation of four compounds: 2,6-dimethoxybenzoquinone (1), (+)-catechin (2), isorhamnetin 3-O-β- D-glucopyranoside (3) and rutin (4). The structure of these compounds were determined through the interpretation of their MS and 1D, 2D-NMR data. This is the first time that these compounds are isolated from Boerhavia erecta L.

scholarly journals New Phenylpropanoid-Substituted Flavan-3-ols from Pu-er Ripe Tea

2014 ◽  
Vol 9 (8) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Mu-Ke Tao ◽  
Min Xu ◽  
Hong-Tao Zhu ◽  
Rong-Rong Cheng ◽  
Dong Wang ◽  
...  
Keyword(s):  
Green Tea ◽  
Camellia Sinensis ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Cd Spectra ◽  
Beneficial Effects ◽  
The Past ◽  
First Time ◽  
Fermentative Process

Pu-er ripe tea is a special microbial post-fermented tea made from Pu-er raw tea, a kind of green tea produced from the leaves of Camellia sinensis var. assamica. It is one of the most consumed teas in the past two decades in China, due to its special flavor, taste, and beneficial effects. This work aimed to obtain diverse catechin structures from Pu-er ripe tea, which led to the isolation of four new phenylpropanoid-substituted flavan-3-ols, puerins C-F (1-4), together with four known flavan-3-ols, (+)-catechin (5), (-)-epicatechin (6), (±)-gallocatechin (7), and (-)-epigallocatechin (8). Their structures were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR, mass and CD spectra. Compounds 1-4, which could be formed in the post-fermentative process of Pu-er tea, were isolated for the first time from tea and Theaceae plant.

scholarly journals Two Compounds from the Endophytic Colletotrichum sp. of Ginkgo biloba

2011 ◽  
Vol 6 (8) ◽  
pp. 1934578X1100600
Author(s):  
Sheng-Liang Zhou ◽  
Song-Lin Zhou ◽  
Mei-Xia Wang ◽  
Shuang-Lin Chen
Keyword(s):  
Spectral Data ◽  
Ginkgo Biloba ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Fermentation Products ◽  
First Time

Two compounds, apigenin-8- C-β-D-glucopyranoside and 2-(hydroxymethylthio)ethanol, were extracted from the fermentation products of a strain of endophytic fungus, Colletotrichum sp. NTB-2, isolated from the leafstalk of Ginkgo biloba. The structures of the two compounds were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data. The compounds were obtained from microorganisms for the first time.

scholarly journals Phytochemical study of Jurinea mongolica Maxim

2018 ◽  
pp. 53-58
Author(s):  
Dumaa M ◽  
Margit Gruner ◽  
Luebkim Tilo ◽  
Solongo T ◽  
Chunsriimyatav G ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Mass Spectrometer ◽  
2D Nmr ◽  
Molecular Structures ◽  
Phytochemical Study ◽  
Aerial Parts ◽  
First Time

There are hispidulin, quercetin-3-О-rutinoside, lupeol, taraxasterol, β-sitosterolwere isolated from the ethylacetate, n-buthanol and petroleum ether fractions of the aerial parts of Jurinea mongolica Maxim. grown in Mongolia. Molecular structures of these compounds were elucidated by using TLC, CC, IR, Mass spectrometer and 1H, 13C and 2D NMR (HSQC, HMBC, 1H-1H COSY, NOESY) methods. All of these compounds were isolated from the Mongolian J. mongolica for the first time. Монгол чоногоно (Jurinea mongolica Maxim.) ургамлын фитохимийн судалгаа Манай орны унаган ургамалд багтдаг Монгол чоногоно (Jurinea mongolica Maxim.) ургамлын газрын дээд хэсгийн этилацетат, н-бутанол, петролейний эфирийн фракцаас гиспидулин, кверцетин-3-О-рутинозид, тараксастерол, лупеол, β-ситостерол бодисыг химийн цэвэр төлөв байдлаар ялгав. Тэдгээр бодисын молекулын бүтэц байгууламжийг НУТ, масс спектрометр, хроматомасс спектроскоп, 1Н ПСР, 13С болон хоѐр хэмжээст ЦСР-ын спектроскопын аргаар таньж тодорхойлов. Судалгааны дүнд 2 фенолт нэгдэл, 2 тритерпен, 1 стеролын төрлийн бодисыг энэ зүйл ургамлаас анх удаа олсон нь шинжлэх ухааны шинэ мэдээлэл болов. Түлхүүр үгс: Монгол чоногоно, Нийлмэл цэцэгтэн, фенолт нэгдэл, тритерпен, стерол

Sign in / Sign up

Export Citation Format

Share Document