Phenolic Derivatives from Radix Astragali and their Anti-inflammatory Activities
2014 ◽
Vol 9
(11)
◽
pp. 1934578X1400901
Two new (3, 4) and two known phenolic derivatives (1, 2) were isolated from Radix Astragali. The structures of 1–4 were elucidated by extensive spectroscopic analysis. The anti-inflammatory activities of the isolated compounds were evaluated in LPS-induced mouse peritoneal macrophages. All four compounds exhibited potent inhibitory effects on TNF-α production and TNF-α, COX-2, IL-1β, IL-6 and iNOS mRNA expression at 50 μM.
2008 ◽
Vol 36
(06)
◽
pp. 1145-1158
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2004 ◽
Vol 150
(2)
◽
pp. 191-201
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