scholarly journals The Effects of Controlled Tempo Manipulations on Cardiovascular Autonomic Function

2019 ◽  
Vol 2 ◽  
pp. 205920431985828 ◽  
Author(s):  
Beatrice Bretherton ◽  
Jim Deuchars ◽  
W. Luke Windsor

Music has been associated with alterations in autonomic function. Tempo, the speed of music, is one of many musical parameters that may drive autonomic modulation. However, direct measures of sympathetic nervous system activity and control groups and/or control stimuli do not feature in prior work. This article therefore reports an investigation into the autonomic effects of increases and decreases in tempo. Fifty-eight healthy participants (age range: 22–80 years) were randomly allocated to either an experimental ( n = 29, tune) or control (rhythm of the same tune) group. All participants underwent five conditions: baseline, stable tempo (tune/rhythm repeatedly played at 120 bpm), tempo increase (tune/rhythm played at 60 bpm, 90 bpm, 120 bpm, 150 bpm, 180 bpm), tempo decrease (tune/rhythm played at 180 bpm, 150 bpm, 120 bpm, 90 bpm, 60 bpm) and recovery. Heart rate, blood pressure, respiration, and muscle sympathetic nerve activity were continuously recorded. The 60 bpm in the tempo decrease stimulus was associated with increases in measures of parasympathetic activity. The 180 bpm in the tempo increase stimulus was also associated with shifts towards parasympathetic predominance. Responses to the stimuli were predicted by baseline %LF. It is concluded that the individual tempi impacted upon autonomic function, despite the entire stimulus having little effect. The 60 bpm in an increasingly slower stimulus was associated with greater vagal modulations of heart rate than faster tempi. For the first time, this study shows that response direction and magnitude to tempo manipulations were predicted by resting values, suggesting that music responders may be autonomically distinct from non-responders.

2010 ◽  
Vol 22 (2) ◽  
pp. 261-271 ◽  
Author(s):  
Eun Young Mun ◽  
Marsha E. Bates ◽  
Evgeny Vaschillo

AbstractSterba and Bauer's Keynote Article discusses the blurred distinction between theoretical principles and analytical methods in the person-oriented approach as problematic and review which of the person-oriented principles are testable under the four types of latent variable models for longitudinal data. Although the issue is important, some arbitrariness exists in determining whether a given principle can be tested within each analytic approach. To close the gap between person-oriented theory and methods and to extend the person-oriented approach more generally, it is necessary to embrace both variable-oriented and person-oriented methods because it is not the individual analytic methods but how studies are implemented as a whole that defines the person-oriented approach. Three areas in developmental psychopathology are discussed in which variable-oriented and person-oriented methods can be complementary. The need to better understand the target system using an appropriate person-specific tool is graphically illustrated. Several concepts of dynamic systems such as attractors, phase transitions, and control parameters are illustrated using experimentally perturbed cardiac rhythms (heart rate variability) as an example in the context of translational alcohol research.


2020 ◽  
pp. 61-110
Author(s):  
Lev Goldfarb

This review summarizes the work of large teams of researchers to prevent two separate encephalitis epidemics in Siberia. The first three lectures sum up an extensive effort to study and control the Tick-borne enceph-alitis (TBE) epidemic in the Kemerovo region of Western Siberia. The study has helped to create a mathematical model that details the TBE epidemic process and offers a quantitative approach to the development of strategies for preventing TBE epidemics. Ten-year effort to combat TBE in the Kemerovo region led to a significant and sustained reduction in TBE morbidity and mortality. Fifty years after completion of this work, the proposed strategy has not been tested in other endemic regions, although the incidence of TBE worldwide has almost doubled, taking hundreds of lives and causing disability in thousands. The second disease described here is Viliuisk encephalomyelitis (VEM), first discovered 150 years ago in a small rural population of Eastern Siberia. The disease later spread to densely populated areas of the Republic of Sakha (Yakutia), reaching epidemic proportions. The three lectures on VEM provide an overview of multi-year studies on clinical presentation, neuropathology, pathogenesis, etiology, and epidemiology of VEM. We report here for the first time how a prolonged hospitalization of VEM patients during the acute and subacute phases of the disease prevent-ed transmission to susceptible individuals in their families and communities, which has helped to put an end to the further spread of this deadly disease. VEM is a new example of a local disease that has spread to a large territory and could potentially invade other countries if left unchecked. This review is based on a series of lectures delivered to different audiences at different times. The purpose of combining discrete topics in a single review is to emphasize approaches to solving problems, to illustrate the main results of the fight against Siberian epidemics and, when possible, reflect on the individual contribution of each researcher.


Author(s):  
I. Sedliar

According to the vast majority of experts, aerobic exercises are basic in fitness. Their effectiveness in the practice involves the rational regulation of load parameters, one of which is the intensity of exercises. However as practice shows the proposed methods for determining the necessary intensity of aerobic exercises do not quite adequately take into account the individual characteristics - age and fitness level. The purpose of the research is to evaluate methods for calculating intensity of aerobic exercise in fitness. In our studies we proceeded from the fact that calculation methods should consider two main trends. At the aging heart rate at rest slightly rises, and the upper pulse during exercises decreases. A higher fitness connected with significant decrease in heart rate at rest and an increase in its upper rate at critical intensity (expanding the range of heart rate during exercise). According to the vast majority of specialists, aerobic exercise is basic in wellness physical culture. Their effective application in the practice of wellness work implies rational regulation of the load parameters, one of which is the intensity of work. As a result the analysis of real situations it was demonstrated that the calculation intensity of aerobic activity according to heart rate indicators using formulas that take into account only the age of the practitioners is applicable in a certain age range (up to about 50-55 years). As age increases the correctness of such calculations decreases and loses its meaning in certain point due to the fact that calculated indicators of heart rate during exercises may be less than those at rest. Karvonen formula which takes into account the individual level of physical fitness for heart rate at rest is more accurate for determining heart rate in aerobic exercise. Its using allows us more correctly determine the lower pulse during exercises declining it because decrease in resting heart rate. However this formula also declining the upper pulse during exercises, although it should increase as the cardiovascular system improves.


2000 ◽  
Vol 278 (3) ◽  
pp. R563-R571 ◽  
Author(s):  
David A. MacLean ◽  
Virginia A. Imadojemu ◽  
Lawrence I. Sinoway

The purpose of the present study was to use the microdialysis technique to simultaneously measure the interstitial concentrations of several putative stimulators of the exercise pressor reflex during 5 min of intermittent static quadriceps exercise in humans ( n = 7). Exercise resulted in approximately a threefold ( P < 0.05) increase in muscle sympathetic nerve activity (MSNA) and 13 ± 3 beats/min ( P < 0.05) and 20 ± 2 mmHg ( P < 0.05) increases in heart rate and blood pressure, respectively. During recovery, all reflex responses quickly returned to baseline. Interstitial lactate levels were increased ( P < 0.05) from rest (1.1 ± 0.1 mM) to exercise (1.6 ± 0.2 mM) and were further increased ( P < 0.05) during recovery (2.0 ± 0.2 mM). Dialysate phosphate concentrations were 0.55 ± 0.04, 0.71 ± 0.05, and 0.48 ± 0.03 mM during rest, exercise, and recovery, respectively, and were significantly elevated during exercise. At the onset of exercise, dialysate K+ levels rose rapidly above resting values (4.2 ± 0.1 meq/l) and continued to increase during the exercise bout. After 5 min of contractions, dialysate K+ levels had peaked with an increase ( P < 0.05) of 0.6 ± 0.1 meq/l and subsequently decreased during recovery, not being different from rest after 3 min. In contrast, H+ concentrations rapidly decreased ( P < 0.05) from resting levels (69.4 ± 3.7 nM) during quadriceps exercise and continued to decrease with a mean decline ( P < 0.05) of 16.7 ± 3.8 nM being achieved after 5 min. During recovery, H+ concentrations rapidly increased and were not significantly different from baseline after 1 min. This study represents the first time that skeletal muscle interstitial pH, K+, lactate, and phosphate have been measured in conjunction with MSNA, heart rate, and blood pressure during intermittent static quadriceps exercise in humans. These data suggest that interstitial K+ and phosphate, but not lactate and H+, may contribute to the stimulation of the exercise pressor reflex.


Cephalalgia ◽  
2004 ◽  
Vol 24 (4) ◽  
pp. 271-279 ◽  
Author(s):  
DL Stronks ◽  
JHM Tulen ◽  
JBJ Bussmann ◽  
LJMM Mulder ◽  
J Passchier

Migraine induces disability and an impaired quality of life, even between attacks. As most studies are based on subjective reports only, this study was set up to objectively quantify the interictal daily activities and heart rate of migraine patients, in relation to their subjectively reported highest realizable level of activity and of symptoms of mood in their habitual environment. Measurements were obtained during a migraine-free 2-day period of 24 patients (age range: 21-57 years) and 24 controls (age range: 18-59 years). Accelerometry was used to quantify the time spent in different postures and movements. The subjective parameters were documented by daily log. Whereas heart rate was similar for patients and controls, migraineurs were found to be significantly less physically active than controls and reported a significantly lower realizable level of activity. In addition, when active, their body motility was less than that of controls. Migraine patients also showed a higher level of sleepiness and lower level of vigour. These interictal behavioural and subjective phenemona objectively illustrate the individual and societal burden of migraine and its chronic impact on both domains.


2020 ◽  
pp. 81-85
Author(s):  
E. P. Popova ◽  
O. T. Bogova ◽  
S. N. Puzin ◽  
D. A. Sychyov ◽  
V. P. Fisenko

Spectral analysis of heart rate variability gives an idea of the role of the autonomic nervous system in the regulation of chronotropic heart function. This method can be used to evaluate the effectiveness of drug therapy. Drug therapy should be carried out taking into account the individual clinical form of atrial fibrillation. Information about the vegetative status of the patient will undoubtedly increase the effectiveness of treatment. In this study, spectral parameters were studied in patients with newly diagnosed atrial fibrillation. The effect of antiarrhythmic drug class III amiodarone on the spectral parameters of heart rate variability was studied.


1970 ◽  
Vol 6 (1) ◽  
pp. 184-193
Author(s):  
Ольга Віговська

У статті теоретично обґрунтовано феномен конструктивного самозбереження особистості як ознаки самоактуалізації, розкриття власного потенціалу і побудови перспективи розвитку особистості та емпірично виявлено ознаки психологічної детермінації домінуючого інстинкту у конструктивній самореалізації жінок з різним соціальним статусом. Зазначено, що проблема самозбереження асоціюється з особливостями прояву інстинкту самозбереження людини, але потреби вищого порядку зумовлюють соціальну природу її поведінки, яка локалізована у найвищій точці самореалізації. Теоретично обгрунтовано, що самореалізація визначає тенденцію раціональної організації життя людини та проявляється у її почутті задоволеністю життям. З’ясовано, що психологічну основу конструктивного самозбереження становлять індивідуально-типологічні характеристики людини, які відображають психофізіологічні та психосоціальні резерви самореалізації особистості. Розроблена програма емпіричного дослідження, а також комплекс використаних методів математичної обробки результатів дослідження дає змогу конкретизувати психологічний зміст детермінації домінуючого інстинкту у конструктивній самореалізації жінок вікового діапазону 35-45 років та з різним соціальним статусом. У жінок, які виховують проблемну (хвору) дитину, домінує інстинкт "егофільного типу", що виражається у їх надмірному егоцентризмі і супроводжується низькими показниками самоактуалізації, на відміну від досліджуваних жінок, які виховують здорових дітей і у яких на фоні вираженої тенденції до самоактуалізації домінує базовий інстинкт "дослідницького типу" та "лібертофільного типу". This article theoretically proves constructive phenomenon of self identity as signs of self-disclosure own potential and prospects of development of individual construction. In addition, it empirically showes signs of psychological determination of the dominant instinct in a constructive self-determination of women with different social statuses. It was noted that the issue of self-preservation is associated with the peculiarities of manifestation of self-preservation instinct of man, but it needs higher-order cause social nature of the behavior that is localized at the highest point of self-realization. It theorized that self-realization determines the trend of rational organization of human life and manifests itself in its sense of life satisfaction. It was found that the psychological basis of constructive self-preservation of the individual make individually-typological characteristics of a person that reflect physiological and psychosocial reserves of self-realization. The developed program of empirical research, as well as the methods used complex mathematical processing of results of research allows to specify the content of the psychological determination of the dominant instinct of constructive self-realization а women age range of 35-45 years and with different social status. Women who bring up the problem child dominates the instinct of self-preservation, which is reflected in their excessive self-centeredness, and is accompanied by low levels of self-actualization, as opposed to the study of women who are raising healthy children and that against the backdrop of a pronounced tendency to self-actualization, dominated by basic instinct "research type" and "independent type."


Author(s):  
R. S. Oliveira ◽  
K. B. A. Pimentel ◽  
M. L. Moura ◽  
C. F. Aragão ◽  
A. S. Guimarães-e-Silva ◽  
...  

Abstract Cutaneous leishmaniasis (CL) is a neglected tropical disease with a wide distribution in the Americas. Brazil is an endemic country and present cases in all states. This study aimed to describe the occurrence, the underlying clinical and epidemiological factors, and the correlation of climatic variables with the frequency of reported CL cases in the municipality of Caxias, state of Maranhão, Brazil. This is a retrospective and descriptive epidemiological study based on data extracted from the Brazilian Information System of Diseases Notification, from 2007 to 2017. Maximum and minimum temperature, precipitation, and relative air humidity data were provided by the Brazilian National Institute of Meteorology. A total of 201 reported autochthonous CL cases were analyzed. The predominance of cases was observed in males (70.1%). The age range between 31 and 60 years old was the most affected, with 96 cases (47.9%). Of the total number of registered cases, 38.8% of the affected individuals were engaged in agriculture-related activities. The georeferenced distribution revealed the heterogeneity of disease occurrence, with cases concentrated in the Western and Southern regions of the municipality. An association was detected between relative air humidity (monthly mean) and the number of CL cases per month (p = 0.04). CL continues to be a concerning public health issue in Caxias. In this context, there is a pressing need to strengthen measures of prevention and control of the disease through the network of health services of the municipality, considering local and regional particularities.


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