scholarly journals Increasing the Signal-to-Noise Ratio: COVID-19 Clinical Synopsis for Outpatient Providers

2020 ◽  
Vol 11 ◽  
pp. 215013272092295
Author(s):  
Zach Sartor ◽  
Burritt Hess
Keyword(s):  
Signal To Noise Ratio ◽  
Review Article ◽  
Medical Community ◽  
Ambulatory Setting ◽  
The Novel ◽  
Medical Providers ◽  
Signal To Noise ◽  
Key Points ◽  
Novel Coronavirus ◽  
Relevant Material

The novel coronavirus (SARS-CoV-2), which is the cause of coronavirus disease (COVID-19 formally 2019-nCoV), has received widespread attention from the medical community. Despite the rapid publication of research on the virus and the disease it causes, there is a lack of concise and relevant material to help busy medical providers navigate recognition and management of the disease in the ambulatory setting. This review article aims to bridge this gap by briefly reviewing the key points of the evaluation and treatment of patients with COVID-19 in the ambulatory clinic environment.

scholarly journals What do we know about COVID-19? A review article

2020 ◽  
Vol 66 (4) ◽  
pp. 534-540 ◽  
Author(s):  
Júlia Maggi Vieira ◽  
Olívia Moura de Paula Ricardo ◽  
Carolina Miranda Hannas ◽  
Tereza Cristina Moreira Kanadani ◽  
Tiago dos Santos Prata ◽  
...  
Keyword(s):  
Scientific Community ◽  
Review Article ◽  
Medical Community ◽  
The Novel ◽  
Clinical Knowledge ◽  
Access To Information ◽  
Health Authorities ◽  
Novel Coronavirus ◽  
Epidemiological Parameters ◽  
Increased Pressure

SUMMARY OBJECTIVES To bring summarized information about what has been published so far regarding Covid-19, facilitating the access to information and a better understanding of this pandemic, and to contribute to the medical community in the decision-making against this virus. METHODS This review article brings collected information from different articles published since the beginning of the pandemic of the 2019 novel coronavirus. KEY RESULTS This paper aggregates and consolidates some epidemiological parameters and clinical knowledge about the novel coronavirus and brings what is new in the search for pandemic control. MAJOR CONCLUSIONS Governments and health authorities are under increased pressure to control the COVID-19 spreading. In this scenario, the scientific community is working hard to produce relevant papers which will help in the next steps against coronavirus. Our review summarized the latest news about SARS-CoV2, evidencing what we know about COVID-19 until now.

scholarly journals Coronavirus Disease 2019 (COVID-19): Future Challenges and Recommendations for Dental Settings

2021 ◽  
Vol 4 (11) ◽  
pp. RV1-RV5
Author(s):  
Najmus Sahar ◽  
Pradeep Tangade ◽  
Vikas Singh ◽  
Surbhi Priyadarshini ◽  
Debashis Roy
Keyword(s):  
Health Care Workers ◽  
Preventive Measures ◽  
Clinical Manifestations ◽  
Virus Transmission ◽  
Review Article ◽  
The Novel ◽  
Medical Practitioners ◽  
Care Workers ◽  
Future Challenges ◽  
Novel Coronavirus

The novel coronavirus outbreak is a contagious disease affecting the countries around the world. The quick advancing nature of pandemic has gripped the entire community making it a public health emergency. Infection control preventive measures are necessary to prevent it from further spreading. Medical practitioners, health care workers and Dentists are at high risk of acquiring and transmission of infection. The virus transmission occurs through respiratory tract, aerosols and droplets. Clinical manifestations of virus vary from mild to severe sickness. This review article mainly emphasizes on all the information collected to date on the virus, and future recommendations for dental settings to manage the further spread of this virus.

scholarly journals The clinical characteristics and treatment approaches of COVID-19: a concise review

2021 ◽  
Author(s):  
Sajjad Eslamkhah ◽  
Nazila Alizadeh ◽  
Khalil Hajiasgharzadeh ◽  
Masoud Eslamkhah ◽  
Ahad Mokhtarzadeh ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Web Of Science ◽  
Close Contact ◽  
Review Article ◽  
Main Concern ◽  
The Novel ◽  
Concise Review ◽  
Potential Benefits ◽  
Characteristic Features ◽  
Novel Coronavirus

A series of cases of pneumonia occurred in China in late 2019. For this type of coronavirus, the WHO formally identified the condition as a coronavirus disease 2019 (COVID-19). They announced that this disease is the recent main concern of health problems in the world. Transfer of this novel coronavirus (nCoV) from human to human exists predominantly among family members, who have close contact with each other. This review article is provided based on the recent findings of COVID-19, which were retrieved by searching PubMed, Google Scholar, Scopus, and Web of Science until December 2020. Here, we highlighted the coronaviruses types, COVID-19 symptoms, epidemiology of the disease, transmission ways, and nCoV related pneumonia pathogenesis and continue with characteristic features and treatment methods. While no approved treatments are available for this type of infection therapy but several drugs may have potential benefits. It seems that identifying the detailed characteristics of the novel coronavirus disease offers the foundation for further research into the production of effective anti-COVID-19 drugs and vaccines.

scholarly journals HPLC Estimation of New Impurity Methyl Ezetimibe in Ezetimibe Drug

2020 ◽  
Vol 32 (6) ◽  
pp. 1309-1313
Author(s):  
Duggirala Parvatha Venkata Vardhani Devi ◽  
Kapavarapu Maruthi Venkata Narayanarao ◽  
Pulipaka Shyamala ◽  
Rallabhandi Murali Krishna ◽  
Komali Siva Prasad
Keyword(s):  
Limit Of Detection ◽  
Signal To Noise Ratio ◽  
Gradient Elution ◽  
Hplc Method ◽  
The Novel ◽  
Signal To Noise ◽  
Drug Substances ◽  
Chromatographic Detection ◽  
Noise Ratio ◽  
Gradient Elution Mode

A new gradient elution mode HPLC method was developed and validated to detect and monitor the novel impurity namely methyl ezitimibe in ezetimibe drug substances. Chromatographic detection and analysis of methyl ezetimibe was performed on XBridge C18 column with mobile phase consisting of 0.02 M phosphate buffer (pH 5) and acetonitrile with 1 mL/min flow rate in gradient elution mode. Methyl ezetimibe was detected and monitored at 248 nm. The calibration curve was linear over range of 0.015 to 0.219% concentration. The limit of detection and quantification were computed as 0.005% (signal to noise ratio 3.60) and 0.015% (signal to noise ratio 15.96), respectively. The precision was 0.97% (%RSD) and accuracy was 93.2 to 98.2% (recovery). The developed method was proved suitable to detect and monitor methyl ezetimibe impurity in ezetimibe drug substances.

Application of Constraint CMA Blind Equalization Algorithm in the Medical Image Restoration

2012 ◽  
Vol 263-266 ◽  
pp. 2109-2112
Author(s):  
Jin Zhang ◽  
Ya Jie Mao ◽  
Li Yi Zhang ◽  
Yun Shan Sun
Keyword(s):  
Image Restoration ◽  
Cost Function ◽  
Medical Image ◽  
Signal To Noise Ratio ◽  
Blind Equalization ◽  
Optimal Solution ◽  
The Novel ◽  
Constant Modulus ◽  
Signal To Noise ◽  
Equalization Algorithm

A constraint constant module blind equalization algorithm for medical image based on dimension reduction was proposed. The constant modulus cost function applied to medical image was founded. In order to improve the effect of image restoration, a constraint item was introduced to restrict cost function, and it guarantees that the algorithm converge the optimal solution. Compared to the traditional methods, the novel algorithm improves peak signal to noise ratio and restoration effects. Computer simulations demonstrate the effectiveness of the algorithm.

scholarly journals COVID-19: A Critical Review on Viral Biochemistry, Environmental Transmission, Therapeutics and Safety Measures

2020 ◽  
Vol 1 (6) ◽  
Author(s):  
Roshni Kumari ◽  
Kumari Pragati Nanda ◽  
Hena Firdaus ◽  
Soumen Dey
Keyword(s):  
Specific Treatment ◽  
Scattered Data ◽  
Review Article ◽  
World Health ◽  
The Novel ◽  
Safety Measures ◽  
Current Scenario ◽  
Novel Coronavirus ◽  
Health Organization

The outbreak of coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is declared pandemic by World Health Organization (WHO) keeping in view its infection rate and toxicity level. The entire world is struggling hard to survive the prevailing health emergency. The authors realise the urgent need of contributing an overview of the present scenario to the researchers who are breathlessly trying to combat this pandemic situation. This review aimed at binding all the scattered data and research available till now on COVID-19 disease starting from its origin to transmission and spread through environmental factors till treatment and the safety measures that should be implemented. This article would possibly help the readers by providing an outlook of current scenario on various perspectives of COVID-19 disease at a single glance. The types, origin and toxicity caused are discussed in brief. The role of contaminated aerosols (viral-laden smoke from tobacco, cigarettes), wastewater, fomites, human and faecal matter are important in spreading the novel coronavirus in the environment. There is no specific treatment till date but clinical trials and diagnosis on several known drugs are on-going. The precaution and safety measures could hopefully reduce number of infections and mortality. The number of infected cases confirmed till 2 August 2020 was 17660523 with 680894 deaths in the world. We tried in this review article to summarize the scattered data available on biochemistry of SARS-CoV-2, environmental spread of virus and the safety measures to combat COVID-19 pandemic.

scholarly journals The Covid-19 Pandemic and its Effect on the Elderly: A Review

2020 ◽  
Vol 5 (3) ◽  
Author(s):  
Maimoona Nadri ◽  
Ujala Zubair
Keyword(s):  
The Elderly ◽  
Medical Community ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Public Health Concern ◽  
The World ◽  
Long Term Consequences ◽  
Novel Coronavirus

In 2019, the world experienced a global public health concern when the novel coronavirus originated from China and affected around fifty-seven thousand people around the world by March 2020. The quick rise in the number of cases and the death toll overwhelmed the scientific and medical community. While all the focus was driven towards finding the epidemiology, the treatment and the management, the mental health aspect of the quarantine was being overlooked. The purpose of this review is to create awareness about the long-term consequences of quarantine, with the focus on the elderly community in Pakistan. 

scholarly journals The Teaching Design and Application of Online - Offline Hybrid Curriculum under the Influence of the Novel Coronavirus Pneumonia Epidemic

2021 ◽  
Vol 245 ◽  
pp. 03065
Author(s):  
Wenjia Xie ◽  
Kun Han ◽  
Xiaoli Zhang ◽  
Xinwei Gao ◽  
Meimei He
Keyword(s):  
The Novel ◽  
Hybrid Courses ◽  
Course Content ◽  
Teaching Objectives ◽  
Key Points ◽  
Hybrid Teaching ◽  
Teaching Design ◽  
Key Issues ◽  
Hybrid Curriculum ◽  
Novel Coronavirus

This paper analyzes the differences between online and offline courses in teaching organization, course content and practice, as well as the differences between hybrid teaching and hybrid courses in concept and emphasis. This paper puts forward the basic principles and requirements of hybrid courses teaching design, and discusses the key points and application scenarios of hybrid courses teaching design from three aspects: teaching objectives, teaching elements and teaching activities. And the key issues that need to be figured out are explained.

scholarly journals Coronavirus Desease 2019 (COVID-19) in Children: Lessons from Pediatric Rheumatology

2020 ◽  
Vol 58 (5) ◽  
pp. 469-479
Author(s):  
M. I. Kaleda ◽  
I. P. Nikishina ◽  
E. S. Fedorov ◽  
E. L. Nasonov
Keyword(s):  
Differential Diagnosis ◽  
Pediatric Rheumatology ◽  
Clinical Presentation ◽  
Multiple Organ ◽  
Medical Community ◽  
The Novel ◽  
New Information ◽  
Life Threatening ◽  
Novel Coronavirus ◽  
Inflammatory Syndrome

The clinical presentation and outcomes of infection with the novel coronavirus (COVID-19) are characterized by exceptional variability in manifestations, which depend on many factors, one of which is the patient’s age. One of the severe life-threatening manifestations in adults is severe acute respiratory syndrome (SARS-CoV-2), in some cases accompanied by the development of multiple organ failure. During the first two to three months of the COVID-19 pandemic, the global medical community was of the opinion that this disease in children is usually mild and not fatal. However, with the accumulation of new information, it became clear that there is a growing recognition of the existence of multisystem inflammatory syndrome in children, chronologically associated with SARS-CoV-2, which can lead to serious consequences. The article presents the main epidemiological, clinical and laboratory characteristics of the syndrome, as well as discusses the issues of its pathogenesis, differential diagnosis with a number of other acute conditions associated with an dysbalance of cytokines.

scholarly journals Invasive aspergillosis associated with COVID-19

2021 ◽  
Vol 31 (5) ◽  
pp. 671-676
Author(s):  
Nikolay V. Ovsyannikov ◽  
Olga A. Bilevich ◽  
Lyudmila A. Zenkova ◽  
Olga V. Vasilieva
Keyword(s):  
Invasive Aspergillosis ◽  
Fatal Outcome ◽  
Invasive Pulmonary Aspergillosis ◽  
World Health ◽  
Medical Community ◽  
The Novel ◽  
Pulmonary Aspergillosis ◽  
Coronavirus Infection ◽  
Novel Coronavirus ◽  
Health Organization

The novel coronavirus (COVID-19) pandemic announced by the World Health Organization in March 2020 has brought new tasks to the medical community that require immediate solutions. Recent studies have shown that invasive aspergillosis associated with coronavirus infection caused by COVID-19 often aggravates the course of the disease and leads to death. The article presents a clinical case of acute invasive aspergillosis in a COVID-19 patient with chronic somatic pathology but no risk factors for developing invasive pulmonary aspergillosis. The disease was progressing rapidly and led to a fatal outcome.Conclusion. In the case presented, invasive pulmonary aspergillosis was diagnosed with the help of histological examination of autopsy material.

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