scholarly journals Stakeholders’ Intention to Adopt Gene Therapy in Malaysia: Effects of Age, Education, and Religion

SAGE Open ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 215824402097020
Author(s):  
Muhammad Adzran Che Mustapa ◽  
Latifah Amin ◽  
Ahmad Firdhaus Arham
Keyword(s):  
Gene Therapy ◽  
Health Care Providers ◽  
Behavioral Intention ◽  
Genetic Material ◽  
Successful Implementation ◽  
Medical Procedure ◽  
Care Providers ◽  
Intention To Adopt ◽  
Predicting Factors ◽  
Validated Questionnaire

Gene therapy is a medical procedure in which new genetic material (genes) are introduced into the human body to treat disorders or diseases. Although the technology holds huge promises for improving human health, it is also one of the most controversial topics in modern medicine. Therefore, research into stakeholders’ intention to adopt gene therapy and its predicting factors is important to influence the successful implementation of this new therapeutic tool. The objective of this article is to assess the effect of background variables such as age, gender, and religion on behavioral intention to adopt gene therapy and its predicting factors. A validated questionnaire was distributed to 421 adult respondents (aged 18 years and older) comprised of two groups: health care providers ( n = 221) and patients ( n = 200). The results of the study suggest that the Malaysian stakeholders involved in the study were cautious although they perceived gene therapy as having high benefits, and were highly accepting from a religious perspective. This was reflected in their high intention to adopt gene therapy. At the same time however, they acknowledged the existence of moderate risks. One-way MANOVA analysis detected significant differences in terms of perceived benefits across ages, and behavioral intention across educational level. However, no significant differences were detected in the comparison of all factors across religions. This study serves as a useful baseline for scientists, government regulators, policy makers, and political leaders for understanding Malaysian acceptance of gene therapy and should encourage more research in the future.

Remote Patient Monitoring in Diabetes: How to Acquire, Manage, and Use All of The Data

2022 ◽  
Author(s):  
Eric L. Johnson ◽  
Eden Miller
Keyword(s):  
Health Care Providers ◽  
Glucose Monitoring ◽  
Successful Implementation ◽  
Care Providers ◽  
Remote Patient Monitoring ◽  
Digital Devices ◽  
Diabetes Technology ◽  
Acquisition Management ◽  
Remote Patient ◽  
Monitoring Devices

The ability of patients and health care providers to use various forms of technology for general health has significantly increased in the past several years with the expansion of telehealth, digital applications, personal digital devices, smartphones, and other Internet-connected platforms and devices. For individuals with diabetes, this also includes connected blood glucose meters, continuous glucose monitoring devices, and insulin delivery systems. In this article, the authors outline several steps to facilitate the acquisition, management, and meaningful use of digital diabetes data that can enable successful implementation of both diabetes technology and telehealth services in primary care clinics.

scholarly journals REASONS WHY PATIENTS BYPASS LOWER LEVEL PUBLIC FACILITIES: A CROSS SECTIONAL STUDY FROM UGANDA

2019 ◽  
Author(s):  
SAMUEL OKORI ◽  
INNOCENT BESIGYE ◽  
JANE FRANCIS NAMATOVU
Keyword(s):  
Health Care Providers ◽  
Tertiary Education ◽  
Cross Sectional Study ◽  
Poor Quality ◽  
Health Facilities ◽  
Care Providers ◽  
Sectional Study ◽  
Cross Sectional ◽  
Validated Questionnaire

Abstract Background The quality of services in Uganda at higher level health facilities are usually affected negatively by congestion when patients bypass care from their primary care health facilities (PCHF). The reason behind this bypass phenomenon in Uganda is limited. This study was conducted among patients receiving care at Lira Regional Referral Hospital in northern Uganda to identify reasons why patients bypass their PCHF. Methods We performed a descriptive cross-sectional study between 29/12/2014 & 30/1/2015, 484 respondents attending the outpatient department were recruited by systematic random sampling. Four focus group discussions (FGDs) each involving 10 participants were conducted. Quantitative data was collected using a validated questionnaire, entered, analysed by Epidata Entry 3.1 and SPSS 18 versions respectively. Descriptive statistics and chi square test for differences in the study population were used. For qualitative data, thematic analysis of transcripts was done. Codes and categories were developed and interrogated following an iterative process based on grounded theory. Results The majority (80.4%) of respondents (71.7% females, mean age 18-35 years, SD 0.85) bypassed their PCHF. Factors associated with bypass were: marital status, distance travelled of >10 km and tertiary education. FGDs reported lack of trust in the health care providers, lack of medicines and diagnostic equipment. Conclusions Poor quality of health services at PCHF encourages seeking care from higher-level facilities. Utilization of PCHF is limited due to poor infrastructure, shortage of medicines and human resource. Improvement of these issues will support PCHF which in turn can help reverse bypass phenomenon.

scholarly journals Identifying factors associated with successful implementation and uptake of an evidence-based voluntary medical male circumcision program in Zambia: the Spear and Shield 2 Program

2019 ◽  
Vol 10 (4) ◽  
pp. 970-977 ◽  
Author(s):  
Violeta J Rodriguez ◽  
Antonio Chahine ◽  
Aileen de la Rosa ◽  
Tae Kyoung Lee ◽  
Nicholas V Cristofari ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Male Circumcision ◽  
Qualitative Data ◽  
Sexual Practices ◽  
Successful Implementation ◽  
Evidence Based ◽  
Voluntary Medical Male Circumcision ◽  
Care Providers ◽  
Medical Male Circumcision ◽  
Implementation And Dissemination

Abstract Voluntary medical male circumcision has been shown to provide a 50%–70% reduction in the risk of HIV infection without contributing to behavioral disinhibition of safer sexual practices. This study examined the interim implementation and dissemination data of Spear and Shield 2, an HIV risk-reduction program in Zambia. The purpose of this interim review was to identify contextual challenges to implementation and implement midcourse corrections associated with sustainability of program delivery. Using a mixed-methods design, quantitative evaluations of organizational functioning, barriers to implementation, burnout, and organizational readiness, as well as qualitative data utilizing the Consolidated Framework for Implementation Research (CFIR), were examined to evaluate program implementation. Participants were 184 health care providers from 46 clinics in Zambia. Successful implementation was associated with better community and leader support, and employee readiness and motivation. Quantitative assessments were not related to implementation and provided a limited picture of implementation outcomes. Results suggest that the qualitative data underlying the CFIR constructs provided a nuanced, contextual assessment of implementation, and dissemination outcomes. The CFIR may be valuable in informing the implementation of evidence-based interventions in other parts of Zambia.

Chilean Health Care Providers’ Perceived Comfort in Performing Oral Rapid Testing for HIV: A Cross-Sectional Study

2020 ◽  
Vol 18 (4) ◽  
pp. 191-197
Author(s):  
Lisette P. Irarrázabal ◽  
Judith A. Levy ◽  
Rosina Cianelli ◽  
Kathleen F. Norr ◽  
L. Michele Issel ◽  
...  
Keyword(s):  
Health Care ◽  
Hiv Testing ◽  
Health Care Providers ◽  
Cross Sectional Study ◽  
Successful Implementation ◽  
Test Results ◽  
Rapid Testing ◽  
Care Providers ◽  
Cross Sectional ◽  
Rapid Hiv Testing

Objectives: To understand key factors influencing Chilean health care providers’ perceived comfort performing oral rapid HIV testing. Design: One hundred and fifty health care providers completed a self-administered questionnaire that included a five-item scale measuring self-perceived comfort in conducting HIV pretest counseling, oral rapid testing, finger-prick testing, and delivering test results. Results: Most participants (60%) envisioned good overall comfort performing oral rapid HIV testing (mean score of 16.21; range 0-20), including doing at least four of the five steps. They perceived least comfort delivering HIV-positive test results during posttest counseling. HIV stigmatizing attitudes reduced self-perceived comfort. Conclusions: Providing training to counter HIV stigmatization while increasing comfort in performing oral rapid testing would help facilitate its successful implementation.

Cancer Gene Therapy

2003 ◽  
Vol 2 (1) ◽  
pp. 51-63 ◽  
Author(s):  
Joanne T. Douglas
Keyword(s):  
Gene Therapy ◽  
Cancer Cells ◽  
Genetic Basis ◽  
Genetic Material ◽  
Cancer Gene Therapy ◽  
Successful Implementation ◽  
Cancer Gene ◽  
Targeted Interventions ◽  
Efficient Gene ◽  
Therapy Strategies

Cancer gene therapy is the transfer of genetic material to the cells of an individual with the goal of eradicating cancer cells, both in the primary tumor and metastases. Cancer gene therapy strategies exploit our expanding knowledge of the genetic basis of cancer, thereby allowing rationally targeted interventions at the molecular level. The successful implementation of cancer gene therapy in the clinic awaits the development of vectors capable of specific and efficient gene delivery to cancer cells. The first clinical applications of cancer gene therapy are likely to be in combination with conventional therapies, such as radiotherapy and immunotherapy.

scholarly journals A betegbiztonságot támogató szervezeti kultúra változása a hazai akkreditációs programot tesztelő intézményekben

2016 ◽  
Vol 157 (42) ◽  
pp. 1667-1673 ◽  
Author(s):  
Judit Lám ◽  
Gergő Merész ◽  
Gyula Bakacsi ◽  
Éva Belicza ◽  
Cecília Surján ◽  
...  
Keyword(s):  
Patient Safety ◽  
Health Care Providers ◽  
Regression Models ◽  
Organisational Culture ◽  
Three Dimensions ◽  
Care Providers ◽  
Logistic Regression Models ◽  
Accreditation Program ◽  
Validated Questionnaire ◽  
The Impact

Introduction: The accreditation system for health care providers was developed in Hungary aiming to increase safety, efficiency, and efficacy of care and optimise its organisational operation. Aim: The aim of this study was to assess changes of organisational culture in pilot institutes of the accreditation program. Method: 7 volunteer pilot institutes using an internationally validated questionnaire were included. The impact study was performed in 2 rounds: the first before the introduction of the accreditation program, and the second a year later, when the standards were already known. Data were analysed using descriptive statistics and logistic regression models. Results: Statistically significant (p<0.05) positive changes were detected in hospitals in three dimensions: organisational learning – continuous improvement, communication openness, teamwork within the unit while in outpatient clinics: overall perceptions of patient safety, and patient safety within the unit. Conclusions: Organisational culture in the observed institutes needs improvement, but positive changes already point to a safer care. Orv. Hetil., 2016, 157(42), 1667–1673.

COPD360social Online Community: A Social Media Review

2018 ◽  
Vol 19 (4) ◽  
pp. 489-491 ◽  
Author(s):  
Michael Stellefson ◽  
Samantha R. Paige ◽  
Julia M. Alber ◽  
Margaret Stewart
Keyword(s):  
Health Care ◽  
Social Media ◽  
Chronic Disease ◽  
Health Care Providers ◽  
Online Community ◽  
Self Management ◽  
Successful Implementation ◽  
Evidence Based ◽  
Care Providers ◽  
Media Review

People living with chronic obstructive pulmonary disease (COPD) commonly report feelings of loneliness and social isolation due to lack of support from family, friends, and health care providers. COPD360social is an interactive and disease-specific online community and social network dedicated to connecting people living with COPD to evidence-based resources. Through free access to collaborative forums, members can explore, engage, and discuss an array of disease-related topics, such as symptom management. This social media review provides an overview of COPD360social, specifically its features that practitioners can leverage to facilitate patient–provider communication, knowledge translation, and community building. The potential of COPD360social for chronic disease self-management is maximized through community recognition programming and interactive friend-finding tools that encourage members to share their own stories through blogs and multimedia (e.g., images, videos). The platform also fosters collaborative knowledge dissemination and helping relationships among patients, family members, friends, and health care providers. Successful implementation of COPD360social has dramatically expanded patient education and self-management support resources for people affected by COPD. Practitioners should refer patients and their families to online social networks such as COPD360social to increase knowledge and awareness of evidence-based chronic disease management practices.

scholarly journals Impact of educational intervention on the best immunization practices among practicing health care professionals in a south Indian city

2021 ◽  
Vol 9 ◽  
pp. 251513552110325
Author(s):  
Juny Sebastian ◽  
Gurumurthy Parthasarathi ◽  
Mandyam Dhati Ravi
Keyword(s):  
Health Care ◽  
Health Care Providers ◽  
Educational Intervention ◽  
Health Care Professionals ◽  
Care Facility ◽  
Care Providers ◽  
Immunization Practice ◽  
Validated Questionnaire ◽  
Study Population ◽  
The Impact

Background and Aims: Maintaining the quality and safety of immunization is as important as the efficacy of vaccines in vaccine-preventable diseases (VPD) programs. The aim of this study was to determine the problems associated with different stages of vaccine use and to assess the outcome of an educational intervention on safety and quality use of vaccines among health care providers. Methods: A pilot prospective interventional study was conducted over a period of 2 years at 271 sites in Mysuru, India. The study population was health care professionals (HCPs) involved in immunization and a sample of parents (one per site). A validated questionnaire was used as a study tool. An educational intervention on best immunization practice was conducted for the enrolled HCPs and the impact of the educational intervention was assessed using the study tool after 3 weeks. Results: The total number of the study population was 594 (323 HCPs and 271 parents). Of these, 41.49% were working at community health care facility and 33.13% were enrolled from primary care centers. There were statistically significant improvements in post interventional assessment of all stages of the immunization process including storage ( p −0.001), transportation ( p −0.001), administration ( p 0.001), monitoring and reporting of adverse events following immunization (AEFIs) ( p −0.001), knowledge of AEFIs ( p 0.001), and HCP-parent communication ( p 0.001). AEFI reporting improved by 30% in the post education phase. Conclusion: Continuous education and motivation can result in positive behavioral changes on best immunization practices amongst HCPs involved in immunization, which may help to improve and maintain the safety and quality use of vaccines in immunization centers irrespective of the type of facility.

scholarly journals Burden and resilience in caregivers of patients on maintenance haemodialysis

2019 ◽  
Vol 7 (11) ◽  
pp. 4033
Author(s):  
Jomon Joy ◽  
Hussain Khan T. J. ◽  
Pretty M. Abraham ◽  
Sreedas Gopalakrishnan
Keyword(s):  
Caregiver Burden ◽  
Health Care Providers ◽  
Maintenance Hemodialysis ◽  
Medical Procedure ◽  
Care Providers ◽  
Cross Sectional ◽  
Maintenance Haemodialysis ◽  
Daily Life Activities ◽  
Resilience Scale ◽  
The Family

Background: Chronic renal failure is one among the chronic illness which due to persistence of the disease has various effects on the physiological, psychological and functional ability of the patient and his family. Although haemodialysis has become a highly safe medical procedure that significantly extended life of such patients, it is nevertheless a stressful and lengthy treatment process. The task of personal life care for such patients falls primarily on the family members. The caregiver is expected to aid in patient’s daily life activities resulting in increased physical and emotional burden. With the considerable level of burden involved the concept of resilience thus become crucial as they could function as protective factors. The current study aims to assess the level of caregiver burden and resilience in caregivers of haemodialysis patients.Methods: A cross sectional observational study was done in 120 caregivers of patients diagnosed as having ESRD on maintenance hemodialysis. Zarit Burden Interview was used for assessing caregiver’s burden. Brief Resilience Scale was used to assess caregiver’s resilience.Results: 35.8% of caregivers had severe caregiver burden while looking after dialysis patients while 45% of caregivers had moderate burden. Caregivers showed low resilience about 72.5% which displays poor problem solving and emotion-focused coping strategies.Conclusions: The study shows that more than 80% of caregivers suffered from moderate to severe burden and poor resilience among them would be a contributing factor. The study also shows that female caregivers were most affected. The burden was significantly higher in caregivers as the years spent on caregiving increased and more hours spent per day looking after the patients. Health-care providers need to address these concerns based on both patient- and caregiver-focused approaches, rather than only patient focused.

scholarly journals Implementation of Universal Health Coverage Program in Kisumu County, Kenya: Importance of Social Marketing Strategies

2020 ◽  
Vol 1 (2) ◽  
pp. p22
Author(s):  
P. Otambo ◽  
L. Nyandieka ◽  
J. Kariuki ◽  
R. Mutisya ◽  
E. Echoka ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Universal Health Coverage ◽  
Reproductive Age ◽  
Ethical Review ◽  
Successful Implementation ◽  
Elderly Persons ◽  
Health Coverage ◽  
Care Providers ◽  
Political Class ◽  
Universal Health

Universal Health Coverage is where communities have access to all needed health services without financial hardship. In Kenya, Universal Health Coverage (UHC) program was launched in December 2018, through a presidential decree. This study aimed to understand population needs, acceptability, and perceptions about UHC implementation. The study was undertaken in four pilot counties of Kisumu, Machakos, Nyeri and Isiolo between February and March 2019, using exploratory qualitative data collection techniques. However, this paper focuses on the County of Kisumu which was selected due to its high prevalence of infectious diseases. Respondents included women of reproductive age, men, youth, and elderly persons. In-depth interviews were conducted among health care providers and managers. Scientific and ethical approval was obtained from the Kenya Medical Research Institute’s Scientific and Ethical Review Unit (SERU). Consenting to participate was individualized. Analysis was done thematically. Findings suggest that UHC was understood variously by different groupings. Sensitization about the UHC programme was done through electronic media, by CHVs, education sessions, political class and outreaches. Planning for the programme was done by holding meetings, trainings for community registration and developing budgets. However there was a lot os misunderstanding, confussion and misconcepts about the UHC concept as it was seen as a means to seek for votes by politicians. Barriers for successful implementation included critically understaffed facilities. 

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