scholarly journals Peak oxygen uptake reference values for cycle ergometry for the healthy Dutch population: data from the LowLands Fitness Registry

2019 ◽  
Vol 5 (2) ◽  
pp. 00056-2018 ◽  
Author(s):  
Caspar Frederik Mylius ◽  
Wilhelmus Petrus Krijnen ◽  
Cornelis Peter van der Schans ◽  
Tim Takken
Keyword(s):  
Oxygen Uptake ◽  
Regression Model ◽  
Reference Values ◽  
Cross Validation ◽  
Peak Oxygen Uptake ◽  
Cycle Ergometry ◽  
Additive Models ◽  
Dutch Population ◽  
Age Related ◽  
Best Fitting

Peak oxygen uptake (V′O2peak) is recognised as the best expression of aerobic fitness. Therefore, it is essential that V′O2peak reference values are accurate for interpreting a cardiopulmonary exercise test (CPET). These values are country specific and influenced by underlying biological ageing processes. They are normally stratified per paediatric and adult population, resulting in a discontinuity at the transition point between prediction equations. There are currently no age-related reference values available for the lifespan of individuals in the Dutch population. The aim of this study is to determine the best-fitting regression model for V′O2peak in the healthy Dutch paediatric and adult populations in relation to age.In this retrospective study, CPET cycle ergometry results of 4477 subjects without reported somatic diseases were included (907 females, age 7.9–65.0 years). Generalised additive models were employed to determine the best-fitting regression model. Cross-validation was performed against an independent dataset consisting of 3518 subjects (170 females, age 6.8–59.0 years).An additive model was the best fitting with the largest predictive accuracy in both the primary (adjusted R2=0.57, standard error of the estimate (see)=556.50 mL·min−1) and cross-validation (adjusted R2=0.57, see=473.15 mL·min−1) dataset.This study provides a robust additive regression model for V′O2peak in the Dutch population.

scholarly journals Reference values for peak oxygen uptake: cross-sectional analysis of cycle ergometry-based cardiopulmonary exercise tests of 10 090 adult German volunteers from the Prevention First Registry

BMJ Open ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. e018697 ◽  
Author(s):  
Daniel Rapp ◽  
Jürgen Scharhag ◽  
Stefan Wagenpfeil ◽  
Johannes Scholl
Keyword(s):  
Heart Rate ◽  
Oxygen Uptake ◽  
Reference Values ◽  
Peak Oxygen Uptake ◽  
Cycle Ergometry ◽  
Maximal Heart Rate ◽  
Exercise Tests ◽  
Cross Sectional ◽  
Men And Women ◽  
Cardiopulmonary Exercise

ObjectiveThis study aims to construct quantile reference values for peak oxygen uptake (V̇O2peak) measured by cycle ergometry-based incremental cardiopulmonary exercise tests.DesignCross-sectional study using quantile regressions to fit sex-specific and age-specific quantile curves. Exercise tests were conducted using cycle ergometry. Maximal effort in the exercise tests was assumed when respiratory exchange ratio  ≥1.1 or lactate ≥8 mmol/L or maximal heart rate ≥90% of the age-predicted maximal heart rate. This was assessed retrospectively for a random subsample with an a priori calculated sample size of n=252 participants.SettingA network of private outpatient clinics in three German cities recorded the results of cycle ergometry-based cardiopulmonary exercise tests to a central database (Prevention First Registry) from 2001 to 2015.Participants10 090 participants (6462 men, 3628 women) from more than 100 local companies volunteered in workplace health promotion programmes. Participants were aged 21 to 83 years, were free of acute complaints and had primarily sedentary working environments.Main outcome measurePeak oxygen uptake was measured as absolute V̇O2peakin litres of oxygen per minute and relative V̇O2peakin millilitres of oxygen per kilogram of body mass per minute.ResultsThe mean age for both men and women was 46 years. Median relative V̇O2peakwas 36 and 30 mL/kg/min at 40 to 49 years, as well as 32 and 26 mL/kg/min at 50 to 59 years for men and women, respectively. An estimated proportion of 97% of the participants performed the exercise test until exertion.ConclusionsReference values and nomograms for V̇O2peakwere derived from a large sample of preventive healthcare examinations of healthy white-collar workers. The presented results can be applied to participants of exercise tests using cycle ergometry who are part of a population that is comparable to this study.

Prediction of VO2peak from the 20-m Shuttle-Run Test in Youth With Down Syndrome

2011 ◽  
Vol 28 (2) ◽  
pp. 146-156 ◽  
Author(s):  
Stamatis Agiovlasitis ◽  
Kenneth H. Pitetti ◽  
Myriam Guerra ◽  
Bo Fernhall
Keyword(s):  
Body Mass Index ◽  
Down Syndrome ◽  
Oxygen Uptake ◽  
Regression Model ◽  
Body Mass ◽  
Prediction Equation ◽  
Peak Oxygen Uptake ◽  
Run Test ◽  
Shuttle Run

This study examined whether 20-m shuttle-run performance, sex, body mass index (BMI), age, height, and weight are associated with peak oxygen uptake (VO2peak) in youth with Down syndrome (DS; n = 53; 25 women, age 8–20 years) and whether these variables can be used to develop an equation to predict VO2peak. BMI, 20-m shuttle-run performance, and sex were significantly associated with VO2peak in youth with DS, whereas age, height, and weight were not. A regression model included only shuttle-run performance as a significant predictor of VO2peak; however, the developed prediction equation had low individual predictability. Therefore, 20-m shuttle-run performance alone does not provide valid prediction of VO2peak in youth with DS. Sex, BMI, age, height, and weight do not improve the prediction of VO2peak.

Acute effects of an arginine-based supplement on neuromuscular, ventilatory, and metabolic fatigue thresholds during cycle ergometry

2015 ◽  
Vol 40 (4) ◽  
pp. 379-385 ◽  
Author(s):  
Roksana B. Zak ◽  
Clayton L. Camic ◽  
Ethan C. Hill ◽  
Molly M. Monaghan ◽  
Attila J. Kovacs ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Ventilatory Threshold ◽  
Grape Seed ◽  
Peak Oxygen Uptake ◽  
Cycle Ergometer ◽  
Cycle Ergometry ◽  
Fatigue Threshold ◽  
Incremental Test ◽  
Paired Samples ◽  
Mean Differences

The purpose of the present study was to examine the effects of an acute dose of an arginine-based supplement on the physical working capacity at the fatigue threshold (PWCFT), lactate threshold (LT), ventilatory threshold (VT), and peak oxygen uptake during incremental cycle ergometry. This study used a double-blinded, placebo-controlled, within-subjects crossover design. Nineteen untrained men (mean age ± SD = 22.0 ± 1.7 years) were randomly assigned to ingest either the supplement (3.0 g of arginine, 300 mg of grape seed extract, and 300 mg of polyethylene glycol) or placebo (microcrystalline cellulose) and performed an incremental test on a cycle ergometer for determination of PWCFT, LT, VT, and peak oxygen uptake. Following a 1-week period, the subjects returned to the laboratory and ingested the opposite substance (either supplement or placebo) prior to completing another incremental test to be reassessed for PWCFT, LT, VT, and peak oxygen uptake. The paired-samples t tests indicated there were significant (P < 0.05) mean differences between the arginine and placebo conditions for the PWCFT (192 ± 42 vs. 168 ± 53 W, respectively) and VT (2546 ± 313 vs. 2452 ± 342 mL·min−1), but not the LT (135 ± 26 vs. 138 ± 22 W), absolute peak oxygen uptake (3663 ± 445 vs. 3645 ± 438 mL·min−1), or relative peak oxygen uptake (46.5 ± 6.0 vs. 46.2 ± 5.0 mL·kg−1·min−1). These findings suggested that the arginine-based supplement may be used on an acute basis for delaying the onset of neuromuscular fatigue (i.e., PWCFT) and improving the VT in untrained individuals.

Age-Related Differences in Perceived Exertion While Walking and Running Near the Preferred Transition Speed

2020 ◽  
Vol 32 (4) ◽  
pp. 227-232
Author(s):  
Stacey M. Kung ◽  
Philip W. Fink ◽  
Stephen J. Legg ◽  
Ajmol Ali ◽  
Sarah P. Shultz
Keyword(s):  
Oxygen Consumption ◽  
Oxygen Uptake ◽  
Relative Intensity ◽  
Perceived Exertion ◽  
Age Groups ◽  
Peak Oxygen Uptake ◽  
Transition Speed ◽  
Age Related ◽  
All Speeds ◽  
Preferred Transition Speed

Purpose: To investigate whether youth and adults can perceive differences in exertion between walking and running at speeds near the preferred transition speed (PTS) and if there are age-related differences in these perceptions. Methods: A total of 49 youth (10–12 y, n = 21; 13–14 y, n = 10; 15–17 y, n = 18) and 13 adults (19–29 y) completed a walk-to-run transition protocol to determine PTS and peak oxygen uptake. The participants walked and ran on a treadmill at 5 speeds (PTS–0.28 m·s−1, PTS–0.14 m·s−1, PTS, PTS+0.14 m·s−1, PTS+0.28 m·s−1) and rated perceived exertion using the OMNI Perceived Exertion (OMNI-RPE) scale. Oxygen consumption was measured during the walk-to-run transition protocol to obtain the relative intensity (percentage of peak oxygen uptake) at PTS. OMNI-RPE scores at all speeds and percentage of peak oxygen uptake at PTS were compared between age groups. Results: The 10- to 12-year-olds transitioned at a higher percentage of peak oxygen uptake than adults (64.54 [10.18] vs 52.22 [11.40], respectively; P = .035). The 10- to 14-year-olds generally reported higher OMNI-RPE scores than the 15- to 17-year-olds and adults (P < .050). In addition, the 10- to 14-year-olds failed to distinguish differences in OMNI-RPE between walking and running at PTS and PTS+0.14 m·s−1. Conclusions: Children aged 10–14 years are less able to distinguish whether walking or running requires less effort at speeds near the PTS compared with adults. The inability to judge which gait mode is less demanding could hinder the ability to minimize locomotive demands.

The effect of prior heavy exercise on the parameters of the power-duration curve for cycle ergometry

2009 ◽  
Vol 34 (6) ◽  
pp. 1001-1007 ◽  
Author(s):  
Akira Miura ◽  
Chiaki Shiragiku ◽  
Yuiko Hirotoshi ◽  
Asami Kitano ◽  
Masako Yamaoka Endo ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
High Intensity ◽  
Peak Oxygen Uptake ◽  
Bicycle Ergometer ◽  
Cycle Ergometry ◽  
Work Rate ◽  
Hyperbolic Function ◽  
Heavy Exercise ◽  
Improved Performance ◽  
Lactate Levels

The tolerable duration (t) of high-intensity cycle ergometry is well characterized by a hyperbolic function of power output (P) with an asymptote (termed the critical power (CP)) and a curvature constant (denoted W′). The purpose of this study was to investigate the effect of prior heavy exercise (W-up) that specifically engenders an acidosis on CP and W′. Eight healthy subjects performed 2 sets of 4 high-intensity square-wave exercise bouts on a bicycle ergometer to estimate CP and W′, with (W-up) and without (control) prior exercise, respectively. Exercise intensities of the 4 main bouts were selected in the range of 90% to 135% peak oxygen uptake so as to reach the limit of tolerance between approximately 1.5 and 10 min. The W-up bout was preceded by 6 min cycling at a work rate halfway between the lactate threshold and peak oxygen uptake (mean ± SD of 153.8 ± 29.8 W) starting 12 min before the main bout. Blood lactate levels ([La]b) just before the main exercise bouts in W-up conditions were significantly higher than those of the control (4.7 ± 1.1 and 1.4 ± 0.4 mEq·L–1, respectively; p < 0.05). However, there were no significant differences in end-exercise [La]b. W-up increased significantly the tolerable duration at every work rate compared with the control, which was attributable exclusively to increased CP (176.5 ± 34.3 and 168.7 ± 31.3 W, respectively; p < 0.05), without any significant change in W′ (11.0 ± 3.2 and 11.0 ± 3.1 kJ, respectively). It is concluded that the prior heavy exercise improved performance mainly because of an enhanced aerobic component of exercise energetics, as indicated by a higher CP and lower increment in the [La]b.

scholarly journals PlanHab: hypoxia exaggerates the bed-rest-induced reduction in peak oxygen uptake during upright cycle ergometry

2016 ◽  
Vol 311 (2) ◽  
pp. H453-H464 ◽  
Author(s):  
Michail E. Keramidas ◽  
Roger Kölegård ◽  
Igor B. Mekjavic ◽  
Ola Eiken
Keyword(s):  
Oxygen Uptake ◽  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Vastus Lateralis ◽  
Bed Rest ◽  
Peak Oxygen Uptake ◽  
Cycle Ergometry ◽  
Vastus Lateralis Muscle ◽  
Before And After ◽  
Exercise Induced

The study examined the effects of hypoxia and horizontal bed rest, separately and in combination, on peak oxygen uptake (V̇o2 peak) during upright cycle ergometry. Ten male lowlanders underwent three 21-day confinement periods in a counterbalanced order: 1) normoxic bed rest [NBR; partial pressure of inspired O2(PiO2) = 133.1 ± 0.3 mmHg]; 2) hypoxic bed rest (HBR; PiO2= 90.0 ± 0.4 mmHg), and 3) hypoxic ambulation (HAMB; PiO2= 90.0 ± 0.4 mmHg). Before and after each confinement, subjects performed two incremental-load trials to exhaustion, while inspiring either room air (AIR), or a hypoxic gas (HYPO; PiO2= 90.0 ± 0.4 mmHg). Changes in regional oxygenation of the vastus lateralis muscle and the frontal cerebral cortex were monitored with near-infrared spectroscopy. Cardiac output (CO) was recorded using a bioimpedance method. The AIR V̇o2 peakwas decreased by both HBR (∼13.5%; P ≤ 0.001) and NBR (∼8.6%; P ≤ 0.001), with greater drop after HBR ( P = 0.01). The HYPO V̇o2 peakwas also reduced by HBR (−9.7%; P ≤ 0.001) and NBR (−6.1%; P ≤ 0.001). Peak CO was lower after both bed-rest interventions, and especially after HBR (HBR: ∼13%, NBR: ∼7%; P ≤ 0.05). Exercise-induced alterations in muscle and cerebral oxygenation were blunted in a similar manner after both bed-rest confinements. No changes were observed in HAMB. Hence, the bed-rest-induced decrease in V̇o2 peakwas exaggerated by hypoxia, most likely due to a reduction in convective O2transport, as indicated by the lower peak values of CO.

scholarly journals Relationships Between Walk/Run Performance and Cardiorespiratory Fitness in Adolescents Who Are Overweight

2001 ◽  
Vol 81 (12) ◽  
pp. 1889-1896 ◽  
Author(s):  
Bart Drinkard ◽  
Jennifer McDuffie ◽  
Serena McCann ◽  
Gabriel I Uwaifo ◽  
Jennifer Nicholson ◽  
...  
Keyword(s):  
Body Composition ◽  
Oxygen Uptake ◽  
Cardiorespiratory Fitness ◽  
Body Fat ◽  
Peak Oxygen Uptake ◽  
Cycle Ergometry ◽  
Percentage Of Body Fat ◽  
Run Test ◽  
Ergometry Test ◽  
Minute Walk

Abstract Background and Purpose. Little is known about the methods used to assess the physical fitness of adolescents who are overweight. We investigated the relationship between walk/run performance and cardiorespiratory fitness in adolescents who are overweight. Subjects. Eight African-American adolescents (5 female, 3 male) and 10 Caucasian adolescents (5 female, 5 male) who were overweight (mean age=14.5 years, SD=2.0, range=12–17; mean body mass index [BMI]=42.9 kg/m2, SD=11.5) participated in this study. Methods. Subjects performed a 12-minute walk/run test. The distances traveled at both 9 minutes (D9) and 12 minutes (D12) were recorded, and the distance traveled between 9 and 12 minutes (D9–12) was calculated. Subjects also completed a maximal cycle ergometry test, during which peak oxygen uptake (V̇o2peak), anaerobic threshold (AT), peak power (Wpeak), and power at the anaerobic threshold (Wat) were determined. Body composition was determined by air displacement plethysmography. Results. The mean percentage of body fat was 48.6% (SD=5.3%, range=40.3%–60.4%). Percentage of body fat and BMI were each inversely related to D9, D12, and V̇o2peak (all P&lt;.005). Peak oxygen uptake (r=.72, P=.0001), V̇o2peak/kg lean body mass (r=.60, P&lt;.005), Wpeak (r=.88, P&lt;.0001), and Wat (r=.72, P=.0007) were all related to D12, with greater r values than for D9. If D9–12was included in regression analyses, D9 did not account for additional variance in any of the cycle ergometry variables. Discussion and Conclusion. These results suggest that an easily obtained measurement of physical performance (distance traveled during a 12-minute walk/run test) is related to cardiorespiratory fitness and to body composition in adolescents who are overweight. The 12-minute walk/run distance is more predictive of cycle ergometry test results than the 9-minute distance.

scholarly journals The Understanding of Peak Oxygen Uptake in Children Aged 8–16

2021 ◽  
Vol 8 ◽  
Author(s):  
Simpson W. L. Wong ◽  
Clare C. W. Yu ◽  
Albert M. Li
Keyword(s):  
Oxygen Uptake ◽  
Children And Adolescents ◽  
Literacy Education ◽  
Peak Oxygen Uptake ◽  
Research Literature ◽  
Accuracy Rate ◽  
Chi Square ◽  
Cross Sectional ◽  
Early Introduction ◽  
Age Related

Objective: To examine the understanding of the concept peak oxygen uptake (peak VO2) among children and adolescents at different ages from a developmental perspective.Methods: A total of 549 children and adolescents aged 8 to 16 were recruited and instructed to fill in a 20-item Peak VO2Understanding Inventory developed with reference to the research literature on peak VO2. We presented the participants with twenty scenarios and asked them to indicate whether peak VO2 would “remain unchanged,” “increase,” or “decrease,” or that there was “insufficient information for a definite answer.” The cross-sectional data was analyzed by employing a series of ANOVA analyses and chi-square association tests. Additional statistical analyses were performed to examine the error patterns and if there were gender differences.Results: Except for the 8-year-old group, the overall accuracy rate did not improve with age. Age-related differences in the choice of answers (“increase,” “decrease,” “unchanged,” and “uncertain”) for determining the resulting peak VO2 after a change of antecedent were observed. Error analysis by item showed that prefactual thinking that is important to understand the concept was emerging rather than fully developed in our child and adolescent samples.Conclusion: The mastery of peak VO2 is not subject to age-related maturation but might demand the acquisition of specific logical reasoning skill such as perfactual thinking. Early introduction of peak VO2 and related concepts is advocated and should be emphasized on the reasoning rather than providing model answers in physical literacy education.

scholarly journals Reference Values for Serum Total Cholesterol Concentrations Using Percentile Regression Model: A Population Study in Mashhad

2019 ◽  
Author(s):  
Habibollah Esmaeily ◽  
Elham Dolat ◽  
Hamid Heidarian Miri ◽  
Ala Taji-Herav ◽  
Omid Kiani
Keyword(s):  
Regression Model ◽  
Total Cholesterol ◽  
Reference Values ◽  
Population Sample ◽  
Serum Total Cholesterol ◽  
High Tc ◽  
Men And Women ◽  
Cut Points ◽  
Age Related ◽  
Increased Risk

Background and Purpose: Serum total cholesterol (TC) concentrations are affected by several factors including ethnicity, diet, geographic, and environmental determinants, and are related to another disease, including hypothyroidism, and renal and liver disease. It is associated with an increased risk of cardiovascular disease, particularly if associated with high levels of serum low-density lipoprotein (LDL). The distribution of TC levels within populations may be useful, and the current study aimed to determine the reference values and specific cut points in a population sample from Mashhad, Iran.Methods: A cross-sectional study was conducted, and data was collected from 6518 individuals (2483 men and 4035 women) aged 25–64 year-old living in Mashhad city using a stratified cluster random sampling design.Reference values for borderline and high TC levels in three age groups were obtained using a percentile regression model. Data were analyzed using Quantreg Software Package and R Ver. 3.1.2 Software.Results: Within the population sample, 38% of the subjects were male and 62% of them were female. The mean and standard deviation for age were found to be 47.07±9 years and 45.28±9 years for men and women, respectively. Percentile regression showed that borderline TC levels for men and women aged 25-64 years were 198-216 mg/dl and 176-243mg/dl, respectively. The values for defining high TC levels were also 226-239 mg/dl in men and 202 - 271 mg/dl in women.Conclusion: Our study estimated reference values and cut points for borderline and high TC separately in both men and women, and age-related sub-groups for a population derived from Mashhad. These findings could be used in local policy plans to allocate health resources. 

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