scholarly journals Modelling the bioinformatics tertiary analysis research process

2021 ◽  
Vol 22 (S13) ◽  
Author(s):  
Sara Pidò ◽  
Pietro Crovari ◽  
Franca Garzotto

Abstract Background With the advancements of Next Generation Techniques, a tremendous amount of genomic information has been made available to be analyzed by means of computational methods. Bioinformatics Tertiary Analysis is a complex multidisciplinary process that represents the final step of the whole bioinformatics analysis pipeline. Despite the popularity of the subject, the Bioinformatics Tertiary Analysis process has not yet been specified in a systematic way. The lack of a reference model results into a plethora of technological tools that are designed mostly on the data and not on the human process involved in Tertiary Analysis, making such systems difficult to use and to integrate. Methods To address this problem, we propose a conceptual model that captures the salient characteristics of the research methods and human tasks involved in Bioinformatics Tertiary Analysis. The model is grounded on a user study that involved bioinformatics specialists for the elicitation of a hierarchical task tree representing the Tertiary Analysis process. The outcome was refined and validated using the results of a vast survey of the literature reporting examples of Bioinformatics Tertiary Analysis activities. Results The final hierarchical task tree was then converted into an ontological representation using an ontology standard formalism. The results of our research provides a reference process model for Tertiary Analysis that can be used both to analyze and to compare existing tools, or to design new tools. Conclusions To highlight the potential of our approach and to exemplify its concrete applications, we describe a new bioinformatics tool and how the proposed process model informed its design.

2010 ◽  
Vol 19 (03n04) ◽  
pp. 159-203 ◽  
Author(s):  
CHEN LI ◽  
MANFRED REICHERT ◽  
ANDREAS WOMBACHER

During the last years a new generation of adaptive Process-Aware Information Systems (PAIS) has emerged, which enables dynamic process changes at runtime, while preserving PAIS robustness and consistency. Such adaptive PAIS allow authorized users to add new process activities, to delete existing activities, or to change pre-defined activity sequences during runtime. Both this runtime flexibility and process configurations at build-time, lead to a large number of process variants being derived from the same process model, but slightly differing in structure due to the applied changes. Generally, process variants are expensive to configure and difficult to maintain. This paper presents selected results from our MinAdept project. In particular, we provide a clustering algorithm that fosters learning from past process changes by mining a collection of process variants. As mining result we obtain a process model for which average distance to the process variant models becomes minimal. By adopting this process model as reference model in the PAIS, need for future process configuration and adaptation decreases. We have validated our clustering algorithm by means of a case study as well as comprehensive simulations. Altogether, our vision is to enable full process lifecycle support in adaptive PAIS.


2020 ◽  
Vol 86 (1) ◽  
pp. 127-137
Author(s):  
V.V. Gavrilov ◽  

This article states the need to change the approach, as well as the forms and methods of teaching in the process of developing students' speech within the subject "The Russian language and Culture of speech". The purpose of the study is to describe the ways of active teaching methods application in order to improve students' speech culture. The author notes that modern teaching methods have ceased to respond to the needs of society and do not contribute to successful socialization of university graduates. The novelty of the study lies in the fact that the author proposes that the work on a text (in the broad sense of the term) should become the main one in the teaching process. . The author proposes an updated process model of trainingenumerates those teaching forms and methods that contribute to the successful implementation of the model, describes the conditions of using these methods in the educational process. According to the author, the modeling of problem-based situations, the use of active teaching forms and methods reveal new opportunities to the teacher, help to develop students' communicative competence, and will largely determine further successful socialization of graduates.


2021 ◽  
Vol 74 (1) ◽  
pp. 114-121
Author(s):  
Vasyl Kovalov ◽  

Active introduction of digital technologies in all spheres of life is one of the main directions of state development as a whole and separate sphere of activity. The issue of using information technologies and systems during forensic examination is the subject of scientific research of many domestic and foreign scientists, but this sphere remains relevant. The introduction of digital technologies in forensic activities is one of the priority areas for the forensic science development at the present stage and has significant development potential. One of the areas of optimization and improvement of forensic activity is the development of methods to automate the formation of forensic experts and unify the description of the research process, identified features, justification and formulation of forensic conclusions, which requires legislative consolidation and regulation, analysis and definition of the subject area and development requirements and algorithms for the operation of the system interface. Unification and standardization of the content of forensic experts' opinions requires the development of common standards and an information system adopted by all subjects of forensic expertise, and meets the needs of practice. The development of an information system for forming an expert opinion and automatically forming an expert opinion will allow formalizing and unifying the description of research and results of forensic examinations, optimizing the time of forensic experts and potentially reducing the number of logical, typographical and technical errors, and simplifying quality control of forensic examinations. The proposed system will not only automate the technical work of registration of research results carried out during forensic examinations, but will also contain research algorithms, which will be stored in the form of data on already conducted research of similar objects (list and sequence of operations, identified features and their parameters).


2021 ◽  
Vol 14 (1) ◽  
pp. 40-41
Author(s):  
Diana Elvianita Martanti ◽  
Nanang Rudi Hartono ◽  
Sunarsasi Sunarsasi

The purpose of this study was to understand and find out the motives and meanings of "Sayur Hanging" carried out by the people of Blitar. Then in the future, the results of this research are expected to provide an understanding of the motives and meanings of "Sayur Hanging" carried out by the people of Blitar. The research method uses a qualitative approach that produces descriptive data in the form of speech or writing and observable behavior from the subject itself. This type of research is qualitative phenomenological. The results of this study are the hanging vegetable phenomenon occurs in a number of areas in Blitar, namely Sananwetan Village and Bendogerit Village, as for the meaning of the hanging vegetable phenomenon from the analysis that the authors get from the interview and analysis process is the activity of hanging vegetables on a pole that almost resembles a clothesline. by a number of residents in an area with the aim of helping people in need.


2021 ◽  
Author(s):  
Svitlana Mashchenko ◽  
◽  
Katerina Goncharova ◽  
Vladyslav Hrebennikov ◽  
◽  
...  

A systematization of approaches to the definition of «sustainable development» has been provided in this article. It has been concluded that there is no unambiguous definition of sustainable development. This term is interpreted by scholars from the standpoint of their own subjective judgments. The definition given in the national strategy of sustainable development of Ukraine until 2030 can be considered as the most acceptable. It has been noted that in the implementation of the concept of sustainable development, the regional (subnational) level should be the determining factor. This is due to the fact that the region is the subject of integration relations, where the goals of sustainable development are most adequate to its position in the system of management of the national economy and regional association. It has been noted that the implementation of sustainable development tasks at the regional level requires: development of socio-economic and environmental development programs; formation of local budgets taking into account the priority of goals and objectives of sustainable development; implementation of a set of measures for balanced development of regions. It has been determined that for further implementation of the concept of sustainable development in the regional dimension, it is necessary to develop a new methodology taking into account the effective allocation of productive forces. It has been emphasized that the deployment of productive forces is a tool to achieve effective implementation of the concept of sustainable development. A scheme to ensure sustainable development of the regions, taking into account the factors of the APF has been suggested by the authors. There are three main areas: development of sustainable development strategies for each region; the formation of local budgets taking into account the priorities and goals of sustainable development and the formation of an effective policy of the APF in the context of sustainable development. It has been noted that the last area is the main one and needs the most attention in the research process. It has been concluded that sustainable development in the region is possible through the development and implementation of regional strategies and programs of sustainable development, as well as in the development of coordinated regional development policy in the context of sustainable development and local budgets taking into account the priority of sustainable development.


Author(s):  
Adam Kadziela

The article complements the methodological discussions with issues related to the participation of young people in social research. The scientific purpose of the article is to analyze, indicate the features and stages of the research process, methods and scope of research in the context of available research on the political participation of young Poles. The subject of the analysis is also the research project “Determinants of the electoral participation of young Poles in 2019” carried out in September 2019.


2019 ◽  
Vol 20 (1) ◽  
pp. 68
Author(s):  
Samsul Hidayat

This research is entitled: "Application of the Quantum Hijaiyah Method in Improving the Ability to Read the Koran of the Muslim Community in West Kalimantan”. The purpose of this study is to guide the convert community (muallaf) to be able to read the Qur'an properly and correctly, equipping them with the ability to practice one of the teachings of Islam, namely to read the holy verses of the Qur'an in order to increase the spirit of converts in practicing Islamic teachings.The object of this research is the Muslim convert community (muallaf) in Senyabang Village, Sanggau District and the Muslim Community in Menjalin Village, Menjalin District, Landak Regency. This qualitative research model targets the social community as an active part of the research process, in order to increase the effectiveness of the data collection and analysis process to produce a recommendation that is truly beneficial for the improvement of the quality of their social life. The community-based research approach is more suitable if it uses an action research model, as applied research that requires dynamic and clinical trials. The results of the study were in the form of application a method of learning the Qur'an in an easier time with the Quantum Hijaiyah method. The training and development participants showed an increase in the mastery of reading hijaiyah letters and verses of the Qur'an during 19 hours of effective learning starting from pre-test, training and post-test activities. Increasing the reading ability of participants is proven by the results of tests and testimonials or acknowledgment from each participant who acknowledges the changes and improvement in the quality of reading the verses of the Qur'an.


2020 ◽  
Vol 24 (3) ◽  
pp. 67-77
Author(s):  
V. V. Devyatkov ◽  
A. V. V.Gabalin

The purpose of research. The goal of this study is to analyze different domestic software packages intended for modeling of business processes involving queues and time parameters. The main analysis criteria are: the possibility of graphical development or conversion of the business process block diagram to the model; automatic generation of simulation model; quick and convenient construction of domain-specific application; the variety of result analysis tools. The relevance of the problems to choose the optimal modeling tool is determined by the need to use only domestic software for business process investigation in the military and some scientific organizations, and by the lack of information about existing software products. In this paper, the subject of study is the Russian simulation modeling environment GPSS Studio.Materials and methods. In this article, the analysis of the possibility of effective usage of GPSS Studio environment during business processes analysis and synthesis is performed. The study was performed on the available examples of different applications of this tool, and by the creation of the model analyzing business processes that are typical for any HR department.Results. Taking into account the performed analysis of functionality and practical applications of the GPSS Studio environment, the good prospects of its application for modeling of business processes involving queues and time parameters are shown. The further system improvements intended for effective business process modeling are proposed.Conclusion. As a result of the performed study, we can do the following conclusions and recommendations:– The GPSS Studio graphical editor can be successfully used for the graphical description of the business processes when it is required to analyze: queues, the load of resources, and the time characteristics of the processing,– The simulation model is automatically generated from the graphical description. The produced model can be finally debugged and verified with the GPSS Studio,– The standalone simulation application working in terms of the subject domain can be built from the simulation model using the simulation environment,– Using this application, it is possible to perform complex business process simulation modeling by means of varying system parameters and performing of singular experiments, a series of dedicated experiments, and optimizing experiments,– Since the GPSS Studio concepts include the possibility to create domain-specific libraries of standard blocks, it is possible to create a library of standard elements similar to IDEF, BPMN, DFD block charts to facilitate faster description and modeling of business processes. After the creation of such a library, there would be no need to manually write GPSS code, since the business process model could be built by a simple connection of standard blocks.


Author(s):  
David Parsons ◽  
Rosemary Stockdale

Multi-User Virtual Environments (MUVEs) are the subject of increasing interest for educators and trainers. In the context of software development, they are beginning to see increasing use both as learning spaces and as a richer means of collaboration for virtual teams. This chapter reflects on a project that developed and evaluated a virtual agile software development workshop hosted in the Open Wonderland MUVE, designed to help learners to understand the basic principles of some core agile software development techniques. The work took a design-based research approach, following a reflective path of development through two major iterations. The authors trace the research process from a real world implementation of the “agile hour” workshop to its virtual incarnation, describing the design philosophy and the constructed virtual artifacts. They conclude by reflecting on the insights into learner perceptions and practical implementations gained from building and evaluating the Open Wonderland workshop.


Sign in / Sign up

Export Citation Format

Share Document