scholarly journals Endogenous endophthalmitis caused by a multidrug-resistant hypervirulent Klebsiella pneumoniae strain belonging to a novel single locus variant of ST23: first case report in China

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Min Xu ◽  
Ang Li ◽  
Haishen Kong ◽  
Weili Zhang ◽  
Hongchao Chen ◽  
...  
Keyword(s):  
Case Report ◽  
Klebsiella Pneumoniae ◽  
Multidrug Resistant ◽  
Single Locus ◽  
Endogenous Endophthalmitis ◽  
First Case ◽  
Single Locus Variant

Endogenous endophthalmitis complicating Klebsiella pneumoniae liver abscess in Europe: case report

2007 ◽  
Vol 28 (2) ◽  
pp. 111-113 ◽  
Author(s):  
Edison Mutsinzi Karama ◽  
François Willermain ◽  
Xavier Janssens ◽  
Marc Claus ◽  
Sigi Van den Wijngaert ◽  
...  
Keyword(s):  
Case Report ◽  
Klebsiella Pneumoniae ◽  
Liver Abscess ◽  
Endogenous Endophthalmitis

scholarly journals Multidrug-Resistant ESBL/AmpC-Producing Klebsiella pneumoniae Isolated from Healthy Thoroughbred Racehorses in Japan

Animals ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 369 ◽  
Author(s):  
Eddy Sukmawinata ◽  
Ryoko Uemura ◽  
Wataru Sato ◽  
Myo Thu Htun ◽  
Masuo Sueyoshi
Keyword(s):  
Klebsiella Pneumoniae ◽  
Genetic Relatedness ◽  
Bacterial Species ◽  
Multidrug Resistant ◽  
Selective Medium ◽  
Major Health Problem ◽  
Disk Diffusion Test ◽  
Single Locus Variant ◽  
Thoroughbred Racehorses ◽  
Klebsiella Spp

Extended-spectrum β-lactamase (ESBL)- and AmpC β-lactamase (AmpC)-producing Klebsiella spp. have become a major health problem, leading to treatment failure in humans and animals. This study aimed to evaluate the presence of ESBL/AmpC-producing Klebsiella spp. isolated from racehorses in Japan. Feces samples from 212 healthy Thoroughbred racehorses were collected from the Japan Racing Association Training Centers between March 2017 and August 2018. ESBL/AmpC-producing Klebsiella spp. were isolated using selective medium containing 1 µg/mL cefotaxime. All isolates were subjected to bacterial species identification (MALDI-TOF MS), antimicrobial susceptibility test (disk diffusion test), characterization of resistance genes (PCR), conjugation assay, and genetic relatedness (multilocus sequence typing/MLST). Twelve ESBL/AmpC-producing Klebsiella pneumoniae (ESBL/AmpC-KP) were isolated from 3.3% of horse samples. Antimicrobial resistance profiling for 17 antimicrobials showed all ESBL/AmpC-KP were multidrug-resistant (MDR). Only 1 isolate was confirmed as an ESBL producer (blaCTX-M-2-positive), whereas the other 11 isolates were plasmid-mediated AmpC (pAmpC) producers (blaCMY positive). On the basis of MLST analysis, the ESBL-KP isolate was identified as sequence type (ST)-133 and four different STs among AmpC-KP isolates, ST-145, ST-4830, ST-4831, and ST-4832, were found to share six of the seven loci constituting a single-locus variant. This is the first study to show K. pneumoniae carrying MDR pAmpC isolated from a racehorse.

Investigation and management of Klebsiella Pneumoniae Outbreak in Intensive Care Unit of Tanta University Emergency Hospital

2021 ◽  
Vol 30 (3) ◽  
pp. 53-58
Author(s):  
Sara Youssef Maxwell ◽  
Mohamed S. Abd Elghafar ◽  
Maii A. Shams Eldeen
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Multidrug Resistant ◽  
Infection Prevention And Control ◽  
Drug Resistant ◽  
Emergency Hospital ◽  
First Case ◽  
Wide Range ◽  
Tract Infections

Background: Klebsiella pneumoniae infection is responsible for a wide range of infections including pneumonia, bacteremia, wound infections, and urinary tract infections. Objective: To investigate and manage the occurrence of multi-drug resistant Klebsiella pneumoniae outbreak in Intensive Care Unit of Tanta University Emergency Hospital. Methodology: The investigation of the outbreak included isolates identification and typing while management included implementation of infection prevention and control precautions; establishment of an Outbreak Control Team; epidemiological investigations; and decontamination of environment. Results: During September 2020, five patients in the Intensive Care Unit in Emergency Hospital of Tanta University had multi drug-resistant Klebsiella pneumoniae identified in samples obtained from a variety of specimens. The fifth case was identified 10 days following confirmation of the first case. The Microbiology laboratory confirmed the five cases had identical Klebsiella pneumoniae strains. This suggests that there was a patient-to- patient spread of multidrug resistant Klebsiella pneumoniae. Conclusion: This investigation revealed the importance of proactive recognition of a possible outbreak, screening of patients transferred from other hospitals, early identification of any unusual microorganisms and implementation of early infection control interventions.

scholarly journals Multidrug-resistant klebsiella pneumoniae-induced sepsis with multiple abscesses: A case report

2021 ◽  
Vol 2 (4) ◽  
Author(s):  
Ye Xiong ◽  
◽  
Jianrong Huang ◽  
Keyword(s):  
Case Report ◽  
Antimicrobial Resistance ◽  
Klebsiella Pneumoniae ◽  
Oral Cavity ◽  
Multidrug Resistant ◽  
Drug Resistant ◽  
Human Intestine ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus

Klebsiella pneumoniae, a Gram-negative bacillus which exists widely in nature, is generally colonized in the human intestine and oral cavity and does not cause disease [1]. However, the emergence and global expansion of hypervirulent and multidrug-resistant clones of K. pneumoniae have been increasingly reported in community-acquired and nosocomial infections. Management of antimicrobial resistance in multi-drug-resistant-K. pneumoniae (MDR-KP) is a major challenge for clinicians [2]. The optimal treatment option for MDR-KP infections is still not well established, which brings huge challenges to clinical treatment [2].

scholarly journals Candida auris emergence in the Himalayan foothills: First case report from Uttarakhand, India

2020 ◽  
Author(s):  
Suneeta Meena ◽  
Ranjana Rohilla ◽  
Neelam Kaistha ◽  
Arpana Singh ◽  
Pratima Gupta
Keyword(s):  
Case Report ◽  
Tertiary Care ◽  
Multidrug Resistant ◽  
Whipple Procedure ◽  
Care Hospital ◽  
Candida Auris ◽  
Flight Mass Spectrometry ◽  
First Case ◽  
The Matrix ◽  
Head Of The Pancreas

Background and Purpose: Candida auris is a rapidly emerging fungus, which is considered globally a cause of concern for public health. This report describes the first case of C. auris fungemia from a tertiary care hospital in the hilly state of Uttarakhand in India. Case report: The patient was a 37-year-old female who underwent a Whipple procedure for the carcinoma of the head of the pancreas. She developed fever 12 days after the operation while recovering from surgery in the hospital. Blood culture yielded C. auris which was identified by the matrix-assisted laser desorption/ionization-time of flight mass spectrometry (Bruker Daltonics, Germany). The patient was successfully treated with caspofungin. Conclusion: In conclusion, C. auris is potentially multidrug resistant, resulting in nosocomial outbreaks and sporadic infections which can be potentially prevented when identified early by implementing contact precautionsBackground and Purpose: Candida auris is a rapidly emerging fungus, which is considered globally a cause of concern for public health. This report describes the first case of C. auris fungemia from a tertiary care hospital in the hilly state of Uttarakhand in India. Case report: The patient was a 37-year-old female who underwent a Whipple procedure for the carcinoma of the head of the pancreas. She developed fever 12 days after the operation while recovering from surgery in the hospital. Blood culture yielded C. auris which was identified by the matrix-assisted laser desorption/ionization-time of flight mass spectrometry (Bruker Daltonics, Germany). The patient was successfully treated with caspofungin. Conclusion: In conclusion, C. auris is potentially multidrug resistant, resulting in nosocomial outbreaks and sporadic infections which can be potentially prevented when identified early by implementing contact precautions.

scholarly journals Community-acquired meningitis caused by a CG86 hypervirulent Klebsiella pneumoniae strain: first case report in the Caribbean

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Bénédicte Melot ◽  
Sylvain Brisse ◽  
Sébastien Breurec ◽  
Virginie Passet ◽  
Edith Malpote ◽  
...  
Keyword(s):  
Case Report ◽  
Klebsiella Pneumoniae ◽  
First Case ◽  
The Caribbean

scholarly journals Osteomyelitis Due to Multiple Carbapenemase-Producing Gram-Negative Bacteria: The First Case Report of a GES-13-ProducingPseudomonas aeruginosaIsolate in Canada

2014 ◽  
Vol 25 (4) ◽  
pp. 229-231 ◽  
Author(s):  
Shadi Sepehri ◽  
Guillaume Poliquin ◽  
Nora Alfattoh ◽  
David Boyd ◽  
Michael Mulvey ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Risk Factor ◽  
Case Report ◽  
Klebsiella Pneumoniae ◽  
Burn Injury ◽  
International Travel ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
First Case

A case of osteomyelitis in an infant following a burn injury sustained in Pakistan caused by a GES-13-producingPseudomonas aeruginosa(the first reported in Canada) and an OXA-48 producingKlebsiella pneumoniaeis described. The present case serves to highlight the importance of international travel as a risk factor for infection with carbapenemase-producing bacteria and the challenges in the laboratory detection of these organisms.

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