scholarly journals Topography and clinical features of iris melanoma

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Jørgen Krohn ◽  
Kristoffer Våge Sundal ◽  
Torbjørn Frøystein
Keyword(s):  
Clinical Features ◽  
Clinical Characteristics ◽  
Two Dimensional ◽  
Inclusion Criteria ◽  
Younger Patients ◽  
Iris Melanoma ◽  
Tumour Diameter ◽  
The Mean ◽  
Tumour Extent

Abstract Background To characterise the topographical and clinical features of primary iris melanoma and to visualise the patterns of tumour extent in the iris. Methods Clinical characteristics of iris melanomas were analysed, and data on their size, shape, and location were converted into a database of two-dimensional iris charts by means of computer-drawing software. The geometric centre of each tumour was entered into corresponding sectors of the chart. The extent of the melanomas was computationally visualised by merging the iris drawings and displaying the number of overlapping tumours on colour-coded iris maps. Results Twenty-nine patients (18 females and 11 males) with a mean age of 52 years met the inclusion criteria. The mean largest tumour diameter was 6.1 mm (range, 1.8–11.0 mm). Five tumours (17%) involved the pupillary margin, 10 (34%) involved the iris root, and 10 (34%) involved both sites. The hemispheric location of the tumour centroid was superior in 3 eyes (11%) and inferior in 25 (89%) (p < 0.0001), and the distribution between the temporal and nasal hemispheres was 17 (61%) and 11 (39%), respectively (p = 0.26). In females, the iris melanomas were located more temporally (p  =  0.02) and had more often originated from a pre-existing naevus (p = 0.03), than in males. There was also shift towards more temporally located melanomas in younger patients. Conclusions The lower temporal iris quadrant is the preferential area of melanoma occurrence and growth. Iris melanoma tends to be more temporally located in females, who compared with males also have a higher proportion of melanomas arising from a pre-existing naevus.

CLINICAL CHARACTERISTICS AND FETO-MATERNAL OUTCOMES IN PREGNANT WOMEN WITH COVID -19 INFECTIONS

2021 ◽  
pp. 30-32
Author(s):  
Gulshan Bano ◽  
Anubha Prashad ◽  
Rakhee Soni ◽  
Mohammed Mishal
Keyword(s):  
Pregnant Women ◽  
Cesarean Delivery ◽  
Clinical Features ◽  
Clinical Characteristics ◽  
Maternal Outcomes ◽  
Hypertensive Disorder ◽  
Co Morbidity ◽  
Hypertensive Disorder Of Pregnancy ◽  
The Mean ◽  
In Pregnancy

Background and objectives:-COVID-19 is ongoing pandemic, caused by novel Corona Virus. There is very scarce information is available about clinical features and feto-maternal outcomes of COVID-19 in pregnancy. Therefore, this study was aimed to determine clinical characteristics and feto-maternal outcomes of pregnant women with COVID-19. Methods- In this retrospective study, we included all pregnant women admitted with COVID-19 over three months. Clinical features, laboratory ndings and feto-maternal outcomes were assessed.Results:-The mean age of the patients was 24 years. Hypertensive disorder of pregnancy was most common associated co-morbidity. Majority of patients (81%) were asymptomatic. Lymphocytopenia was seen in 58% of the patients and 47% had elevated levels of CRP. All patients who presented in rst trimester had spontaneous abortion. There is relatively higher rate of preterm birth (21%) and cesarean delivery(43%). All the neonates were tested negative for COVID-19. Conclusion;- There is relatively higher rate of cesarean delivery. Overall feto-maternal outcome was good and there was no evidence of vertical transmission.

scholarly journals Clinical Features and Prognosis of Invasive Ventilation in Hospitalized Patients with COVID-19: A Retrospective Study

2020 ◽  
Vol 10 (6) ◽  
Author(s):  
Poupak Rahimzadeh ◽  
Hamid Reza Faiz ◽  
Reza Farahmandrad ◽  
Babak Hassanlouei ◽  
Azadeh Habibi ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Respiratory Rate ◽  
Critically Ill ◽  
Clinical Features ◽  
Critically Ill Patients ◽  
Clinical Characteristics ◽  
Laboratory Data ◽  
World Health ◽  
The Mean ◽  
Lung Ct

Background: World Health Organization (WHO) declared that the outbreak of COVID-19 constituted a public health emergency of global concern. Objectives: Owing to limited data on critically ill patients admitted to ICU, we aimed to describe the clinical characteristics and prognosis of these patients based on ventilatory variables and clinical features. Methods: In this retrospective study, 45 critically ill patients with laboratory-confirmed COVID-19 who were admitted to Intensive Care Unit (ICU) wards of the hospital from April 8 to May 9, 2020, were enrolled. Medical files of the patients were reviewed, and demographic and clinical characteristics, laboratory data, lung CT scan findings, causes of intubation, and outcomes of the patients were all collected. Results: The median age of the patients was 67 years (range 22 to 91), 64% were men, and hypertension was the most common comorbidity. History of close contact with previously confirmed patients was positive in 62.2% of the patients. The mean time from symptom onset to hospital admission was 5.98 ± 2.93 days. The most common symptoms at the onset of illness were dyspnea (95.6%), and gastrointestinal symptoms (22.2%) were rare. The average length of the intubation was 4.84 ± 3.28 days. The distribution of intubation causes in the deceased patients was significantly more than the recovered patients (P = 0.031). The mean score of lung CT involvement in deaths (370.26 ± 207.50) was significantly higher than the recovered patients (235.71 ± 81.21) (P = 0.042). Length of the intubation had a statistically direct correlation with respiratory rate (P = 0.03). Conclusions: Most of the critically ill patients admitted to ICU were older men and had poor outcomes with a high mortality rate. Furthermore, the score of chest CT involvement and respiratory rate are important prognostic factors in determining the severity of the illness, requiring ventilatory support, and outcome.

Clinical Features and Pharmacological Treatment of Migraine Patients Referred to Headache Specialists in Canada

Cephalalgia ◽  
2006 ◽  
Vol 26 (5) ◽  
pp. 578-588 ◽  
Author(s):  
SE Jelinski ◽  
WJ Becker ◽  
SN Christie ◽  
R Giammarco ◽  
GF Mackie ◽  
...  
Keyword(s):  
Clinical Features ◽  
Pharmacological Treatment ◽  
Clinical Characteristics ◽  
Medication Overuse ◽  
Pharmacological Therapy ◽  
Significant Problem ◽  
Prophylactic Drug ◽  
Before And After ◽  
The Mean ◽  
Medication Changes

We set out to examine selected clinical characteristics of migraine patients referred to neurologists specializing in headache in Canada, and to document their pharmacological therapy both before and after consultation with the neurologist. Demographic, clinical and pharmacotherapy data were collected at the time of consultation for 606 patients referred to five headache clinics and who were given a migraine diagnosis by the neurologist. Data were analysed as part of the Canadian Headache Outpatient Registry and Database (CHORD) Project. The mean age of the migraine patients was 39.7 years; and 82.5% were female. The majority of patients suffered severe impact from their headaches. Prior to consultation, 48.7% were taking a triptan; after consultation, 97.2% were on a triptan. Before consultation, 30.9% were on a prophylactic drug; after consultation, 70.4% were. 20.8% of patients were medication overusers. Of these medication overusers, 42.4% were overusing an opiate, usually in combination with other analgesics; 21.6% were overusing a triptan. Medication changes made by the neurologists at consultation included a large increase in the use of both triptans and prophylactic medications. Medication overuse, particularly opiate overuse, remains a significant problem in patients with migraine in Canada.

scholarly journals AB0668 CLINICAL CHARACTERISTICS OF RADIOGRAPHIC AND NON RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS IN A GROUP OF TUNISIAN SPONDYLOARTHRITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1629.1-1629
Author(s):  
K. Ben Abdelghani ◽  
Y. Gzam ◽  
A. Fazaa ◽  
S. Miladi ◽  
K. Ouenniche ◽  
...  
Keyword(s):  
Clinical Features ◽  
Clinical Characteristics ◽  
Axial Spondyloarthritis ◽  
Age At Onset ◽  
Diagnostic Delay ◽  
Hla B27 ◽  
The Family ◽  
History Of ◽  
The Mean ◽  
Predominantly Female

Background:In the literature, non radiographic axial Spondyloarthritis (nr-SpA) is predominantly female with a shorter period of evolution and similar peripheral manifestations to radiographic axial spondyloarthritis (r-SpA). However, we do not have Tunisian studies comparing the two groups of axial spondyloarthritis (ax-SpA).Objectives:The aim of this study was to assess the epidemiological and clinical differences between nr-SpA and r-SpA in a group of Tunisian ax-SpA.Methods:Two hundred patients with ax-SpA (ASAS 2009 criteria) were retrospectively included and classified as r-Spa characterized by the presence of radiographic sacroiliitis and nr-SpA defined by the presence sacroiliitis only on MRI or HLA B27 antigen with other clinical features. The different demographic and clinical parameters were compared between the nr-SpA and r-SpA groups.Results:One hundred thirty-eight men and 62 women were included with a sex ratio of 2,2. The mean age was 43,3 ± 11,2 years and the mean period of evolution was 10,7 ± 8,4 years. The patients were divided to r-SpA in 80% of cases (n = 160) and nr-SpA in 20% of cases (n = 40).Women were more present in the nr-SpA group with 47,5% of women versus 26.8% of women in the r-SpA group (p = 0,01). The patients with nr-SpA were younger with a mean age of 39,4 ± 13,4 years versus 44,3 ± 10,4 years in patients with r-SpA (p = 0,03). The mean period of evolution was shorter in nr-SpA group (5,8 ± 4,9 years vs 11.9 ± 8.5; p <0.001). The family history of SpA was more frequent in nr-SpA group (17.5% vs 4.3%, p = 0.004). Arthritis were more frequent in nr-SpA (42.5% vs 13.7%; p <0.0001). Similarly, enthesitis were more frequent in nr-SpA group (45% vs 15.6%; p <0.0001).No statistically significant differences were found in the following parameters: age at onset of symptoms, diagnostic delay, HLA B-27 antigen and dactylitis.Conclusion:The clinical features were different in the 2 groups of ax-SpA: Patients with nr-SpA were more female and had more peripheral manifestations while patients with r-SpA were older and with longer period of evolution.References:[1]de Winter JJ, et al. Arthritis Res Ther 2016; 18:196[2]Malaviya AN, et al. Int J Rheum Dis 2015; 18(7):736–41Disclosure of Interests:None declared

scholarly journals Circumscribed choroidal haemangioma: clinical and topographical features

2019 ◽  
Vol 103 (10) ◽  
pp. 1448-1452 ◽  
Author(s):  
Jørgen Krohn ◽  
Pukhraj Rishi ◽  
Torbjørn Frøystein ◽  
Arun D Singh
Keyword(s):  
Optic Disc ◽  
Young Patients ◽  
Subretinal Fluid ◽  
Height Ratio ◽  
Ocular Fundus ◽  
Tumour Diameter ◽  
Tumour Margin ◽  
Close Proximity ◽  
The Mean ◽  
Tumour Extent

AimsTo characterise the clinical and topographical features of circumscribed choroidal haemangioma (CCH) and to visualise the patterns of tumour extent in the ocular fundus.MethodsData on the size, shape and location of 113 CCH were converted into a database of two-dimensional retinal charts by means of computer drawing software. The extent of the tumours was visualised by merging the charts and displaying the number of overlapping tumours on colour-coded maps.ResultsThe mean largest tumour diameter was 7.2 mm (range, 2.5–11.0 mm), mean tumour height was 2.4 mm (range, 0.7–4.6 mm) and mean diameter/height ratio was 3.2 (range, 2.1–6.0). The mean distance from the posterior tumour margin to the foveola and optic disc margin was 1.7 mm (range, 0–15 mm) and 2.4 mm (range, 0–11 mm), respectively. The hemispheric location of the tumour centroid was temporal in 75 eyes (66%) and nasal in 38 (34%) (p=0.0005) and the distribution between the superior and inferior hemispheres was 68 (60%) and 45 (40%), respectively (p=0.03). The presence of subretinal fluid (SRF) was significantly associated with young age at diagnosis (p=0.0002), low tumour diameter/height ratio (p=0.0004), nasal hemisphere location (p=0.006) and close proximity to the optic disc (p=0.004).ConclusionsThe superotemporal quadrant close to the macula is the most frequent location of CCH. The tumours are generally characterised by a diameter/height ratio of >2. Tumours in young patients, with marked elevation, in nasal hemisphere and in proximity to the optic disc are associated with SRF exudation.

A one-dimensional self-gravitating stellar gas

1966 ◽  
Vol 25 ◽  
pp. 46-48 ◽  
Author(s):  
M. Lecar
Keyword(s):  
Gravitational Field ◽  
Phase Space ◽  
Motion Picture ◽  
Space Distribution ◽  
Two Dimensional ◽  
One Dimensional ◽  
Phase Space Distribution ◽  
Dimensional Phase Space ◽  
The Mean

“Dynamical mixing”, i.e. relaxation of a stellar phase space distribution through interaction with the mean gravitational field, is numerically investigated for a one-dimensional self-gravitating stellar gas. Qualitative results are presented in the form of a motion picture of the flow of phase points (representing homogeneous slabs of stars) in two-dimensional phase space.

Comparison of Heffner Criteria and Light Criteria in Differentiating Exudative and Transudative Pleural Effusion

2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta
Keyword(s):  
Pleural Effusion ◽  
Cross Sectional Study ◽  
Pleural Space ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
The Common ◽  
The Mean ◽  
Exudative Pleural Effusion

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.

CLINICAL CHARACTERISTICS OF THE CHRONIC DACRYOCYSTITIS AND THE SUCCESS RATE OF EXTERNAL DACRYOCYSTORHINOSTOMY

2015 ◽  
pp. 29-34
Author(s):  
Van Nam Phan ◽  
Ba Kien Tran
Keyword(s):  
Success Rate ◽  
Key Words ◽  
Clinical Characteristics ◽  
Lacrimal Duct ◽  
Interventional Study ◽  
Chronic Dacryocystitis ◽  
External Dacryocystorhinostomy ◽  
The Mean

Purpose: To determine the clinical characteristics of the chronic dacryocystitis and the success rate of external dacryocystorhinostomy. Methods: The retrospective, interventional study without comparing on 27 patients (32 eyes) of chronic dacryocystitis who underwent dacryocystorhinostomy (DCR) from 2010 to 2011. Results were evaluated with standards: epiphora, purelence, lacrimal duct irrigation. Results: Over period of 6 months, 27 patients including 25 (92.59%) female, 2 (7.41%) male. The mean age was 49.8 years (range, 22-79 years). All patients demonstrated epiphera (range, 3 months – 11 years). Dacryocystorhinostomy was performed unilaterally in 81.48%, bilateral 18.52%. Successrate was 90.06% overall. Conclusions: Although techniques in dacryocystorhinostomy of DUPUY-DUTEMPS is old, its result is mainstay of treatment for chronic dacryocystitis in Vietnam. Key words: Dupuy-Dutemps, chronic dacryocystitis

Effect of Surgical Versus Pharmacological Decompression of Ludwig’s Angina on Airway Compromise among Nigerian Patients

2020 ◽  
Author(s):  
Ekaniyere EB
Keyword(s):  
Length Of Hospital Stay ◽  
Surgical Decompression ◽  
Airway Compromise ◽  
Inclusion Criteria ◽  
Hospital Stays ◽  
Ludwig’S Angina ◽  
The Mean ◽  
The University ◽  
Ludwig's Angina ◽  
Gender Type

Background: Even though the decompression of the cellulitis phase of Ludwig’s angina (LA) by surgical or pharmacological approach is well documented, it is unclear which approach is more effective. Objective: We aim to compare the outcome of treatment between surgical versus pharmacological decompression in patients with LA. Subjects and Methods: A retrospective cohort study was designed. Data were collected from the case notes of patients that met the inclusion criteria from 2004 to 2018 at the University of Benin Teaching Hospital, Nigeria.The data were age, gender, type of decompression approach, length of hospital stay (LOS) and airway compromise. Result: A total of 62 patients comprising 37(59.7%) surgical decompression group and 25(40.3%) pharmacological decompression group were studied. Thirty-six (58.1%) males and 26 (41.9%) females were studied. Their mean age and standard deviation were 40.6 years and 11.9 years respectively. The mean length of hospital stays between the pharmacological and surgical decompression groups were 8.05 days and 13.8 days respectively. The incidence of airway compromise in the surgical decompression group was 19.9% lower than that of the pharmacological decompression group (P=0.47), which was not significant. The type of decompression approach also failed to influence the incidence of airway compromise (P = 0.41). Conclusion: The use of surgical versus pharmacological decompression does not significantly alter the incidence of airway compromise in the management of LA. The Patients that had surgical decompression had a shorter stay in the hospital as compared to those who had pharmacological decompression. This was not statistically significant.

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