The prevalence of denture stomatitis in cigarette and hookah smokers and opium addicts: findings from Rafsanjan Cohort Study

Abstract Background The aim of this study was to investigate the association of denture stomatitis prevalence with cigarette, hookah and opium consumption and also dose–response relationship between the cigarette smoking duration and odds of denture stomatitis in population of Rafsanjan cohort center. Methods This cross-sectional study based on data of Rafsanjan Cohort Study (RCS) with 10,000 participants. After applying inclusion and exclusion criteria, 1619 participants were included in the analysis. Data were collected by oral examination and completion of pre-designed questionnaires to assess denture hygiene, smoking behavior, opium use and some other exposure variables. Multivariable logistic regression models were fitted to investigate possible association of cigarette, hookah and opium consumption and denture stomatitis. Results Prevalence of denture stomatitis among all 1619 denture wearers was 21.6%. Cigarette smoking was associated with a higher odds of denture stomatitis, with the adjusted odds ratio (95% CI) of 2.29 (1.53–3.41). Also, dose–response increases were observed with the highest odds ratio in the 4th quartile for denture stomatitis (p-value < 0.001). Opium consumption was associated with a decreased odds of denture stomatitis (adjusted OR; 0.81, 95% CI 0.58–1.13) which was not statistically significant. Also interaction between opium consumption and cigarette smoking was not associated with higher odds of denture stomatitis (adjusted OR: 1.65, 95% CI 0.85–3.22). Conclusions Based on the findings of the present study, while cigarette smoking had a dose–response relationship with the increased odds of denture stomatitis; this association was not found with opium consumption.

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Sa1789 – Dose–Response Relationship Between Cigarette Smoking and Ulcerative Colitis : A Nationwide Population-Based Study

Gastroenterology ◽

10.1016/s0016-5085(19)37856-4 ◽

2019 ◽

Vol 156 (6) ◽

pp. S-403

Author(s):

Seona Park ◽

Jaeyoung Chun ◽

Kyungdo Han ◽

Hosim Soh ◽

Eun Ae Kang ◽

...

Keyword(s):

Ulcerative Colitis ◽

Cigarette Smoking ◽

Dose Response ◽

Population Based ◽

Response Relationship ◽

Dose Response Relationship ◽

Population Based Study

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There is no Dose-response Relationship between Allogeneic Blood Transfusion and Healthcare-associated Infection: A Retrospective Cohort Study

10.21203/rs.2.17342/v2 ◽

2020 ◽

Author(s):

Yu Lv ◽

Qian Xiang ◽

Jia Lin ◽

Ying Zong Jin ◽

Ying Fang ◽

...

Keyword(s):

Logistic Regression ◽

Cohort Study ◽

Dose Response ◽

Retrospective Cohort ◽

Response Relationship ◽

Spline Regression ◽

Blood Products ◽

Healthcare Associated Infection ◽

Dose Response Relationship ◽

Healthcare Associated

Abstract BackgroundThe association between allogeneic blood transfusion (ABT) and healthcare-associated infection (HAI) is considered dose-dependent. However, this association may be confounded by transfusion duration, as prolonged hospitalization stay increases the risk of HAI. Also, it is not clear whether specific blood products have different dose-response risks.MethodsIn this retrospective cohort study, a logistic regression was used to identify confounding factors, and the association between specific blood products and HAI were analyzed. Then Cox regression and restricted cubic spline regression was used to visualize the hazard of HAI per transfusion product.ResultsOf 215338 inpatients observed, 4.16% were transfused with a single component blood product. With regard to these transfused patients, 480 patients (5.36 %) developed a HAI during their hospitalization stay. Logistic regression showed that red blood cells (RBCs) transfusion, platelets transfusion and fresh-frozen plasmas (FFPs) transfusion were risk factors for HAI [odds ratio (OR) 1.893, 95% confidence interval (CI) 1.656–2.163; OR 8.903, 95% CI 6.646–11.926 and OR 1.494, 95% CI 1.146–1.949, respectively]. However, restricted cubic spline regression analysis showed that there was no statistically dose-response relationship between different transfusion products and the onset of HAI.ConclusionsRBCs transfusion, platelets transfusion and FFPs transfusion were associated with HAI, but there was no dose-response relationship between them.

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Dose–response relationship between inorganic arsenic exposure and lung cancer among arseniasis area residents with low methylation capacity: A population-based cohort study

European Journal of Cancer ◽

10.1016/s0959-8049(16)61545-9 ◽

2016 ◽

Vol 61 ◽

pp. S154

Author(s):

P.J. Liao ◽

K.H. Hsu

Keyword(s):

Lung Cancer ◽

Cohort Study ◽

Dose Response ◽

Arsenic Exposure ◽

Inorganic Arsenic ◽

Population Based ◽

Response Relationship ◽

Dose Response Relationship ◽

Methylation Capacity

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Setting-Specific and Symptom-Specific Association between Secondhand Smoke Exposure and Depressive Symptoms

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16071249 ◽

2019 ◽

Vol 16 (7) ◽

pp. 1249

Author(s):

Xiaohua Ye ◽

Jingya Huang ◽

Liang Xia ◽

Xiaojun Xu ◽

Xiao Gong ◽

...

Keyword(s):

Depressive Symptoms ◽

Dose Response ◽

Secondhand Smoke ◽

Negative Binomial ◽

Negative Binomial Regression ◽

Response Relationship ◽

Dose Response Relationship ◽

Cross Sectional ◽

Shs Exposure ◽

The Impact

Few studies have focused on the potential relationship between secondhand smoke (SHS) exposure and depressive symptoms. This study aimed to explore the potential association between SHS exposure and depressive symptoms and differentiate this association in setting-specific exposure and symptom-specific outcomes. A cross-sectional study was conducted in Guangdong province of China from September to December 2010 using a multistage sampling method to randomly sample adults aged 18 years and older. SHS exposure was defined as inhalation by non-smokers of the smoke exhaled from smokers for at least 1 day a week in the past 30 days. Depressive symptoms were measured using the nine-item Patient Health Questionnaire. The zero-inflate negative binomial regression models were used to explore the associations between SHS exposure and depressive symptoms. A total of 2771 non-smokers were included in this study, with mean age of 49.6 ± 14.0 years and 70.3% of females. The prevalence of depressive symptoms was significantly higher in participants with SHS exposure than in those without exposure (incidence rate ratio (IRR) = 1.32, 95% confidence interval (CI) 1.16–1.51), and there were similar positive associations for SHS exposure in medical facilities (IRR = 1.37, 95% CI 1.17–1.61) and in schools (IRR = 1.46, 95% CI 1.20–1.77). Notably, there was a monotonically increasing dose-response relationship between frequency of SHS exposure and depressive symptoms. When differentiating this relationship by the dimensions of depressive symptoms, there were similar dose-response relationships for cognitive-affective and somatic symptoms. When differentiating this relationship by sex, only females showed a significant dose-response relationship. Our findings suggest dose-response relationships between SHS exposure and depressive symptoms in sex-specific and symptom-specific manners. Future longitudinal studies are needed to establish the biological mechanisms of the impact of SHS exposure.

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Dose–response relationship between treatment delay of smear-positive tuberculosis patients and intra-household transmission: a cross-sectional study

Transactions of the Royal Society of Tropical Medicine and Hygiene ◽

10.1016/j.trstmh.2008.04.027 ◽

2008 ◽

Vol 102 (8) ◽

pp. 797-804 ◽

Cited By ~ 35

Author(s):

Xu Lin ◽

Virasakdi Chongsuvivatwong ◽

Lu Lin ◽

Alan Geater ◽

Ren Lijuan

Keyword(s):

Dose Response ◽

Treatment Delay ◽

Cross Sectional Study ◽

Response Relationship ◽

Sectional Study ◽

Dose Response Relationship ◽

Cross Sectional ◽

Tuberculosis Patients ◽

Household Transmission

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A dose-response relationship between short sleeping hours and childhood obesity: results of the Toyama Birth Cohort Study

Child Care Health and Development ◽

10.1046/j.1365-2214.2002.00260.x ◽

2002 ◽

Vol 28 (2) ◽

pp. 163-170 ◽

Cited By ~ 221

Author(s):

Michikazu Sekine ◽

Takashi Yamagami ◽

Kyoko Handa ◽

Tomohiro Saito ◽

Seiichiro Nanri ◽

...

Keyword(s):

Cohort Study ◽

Childhood Obesity ◽

Birth Cohort ◽

Dose Response ◽

Birth Cohort Study ◽

Response Relationship ◽

Dose Response Relationship

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There is no Dose-response Relationship between Allogeneic Blood Transfusion and Healthcare-associated Infection: A Retrospective Cohort Study

10.21203/rs.2.17342/v1 ◽

2019 ◽

Author(s):

Yu Lv ◽

Ying Fang ◽

Qian Xiang ◽

Jia Lin ◽

Yu J Wu ◽

...

Keyword(s):

Logistic Regression ◽

Cohort Study ◽

Dose Response ◽

Retrospective Cohort ◽

Response Relationship ◽

Spline Regression ◽

Blood Products ◽

Healthcare Associated Infection ◽

Dose Response Relationship ◽

Healthcare Associated

Abstract Background The association between allogeneic blood transfusion (ABT) and healthcare-associated infection (HAI) is considered dose-dependent. However, this association may be confounded by transfusion duration, as prolonged hospitalization stay increases the risk of HAI. Also, it is not clear whether specific blood products have different dose-response risks. Methods In this retrospective cohort study, a logistic regression was used to identify confounding factors, and the association between specific blood products and HAI were analyzed. Then Cox regression and restricted cubic spline regression was used to visualize the hazard of HAI per transfusion product. Results Of 215338 inpatients observed, 4.16% were transfused with a single component blood product. With regard to these transfused patients, 480 patients (5.36 %) developed a HAI during their hospitalization stay. Logistic regression showed that red blood cells (RBCs) transfusion, platelets transfusion and fresh-frozen plasmas (FFPs) transfusion were risk factors for HAI [odds ratio (OR) 1.893, 95% confidence interval (CI) 1.656–2.163; OR 8.903, 95% CI 6.646–11.926 and OR 1.494, 95% CI 1.146–1.949, respectively]. However, restricted cubic spline regression analysis showed that there was no statistically dose-response relationship between different transfusion products and the onset of HAI. Conclusions RBCs transfusion, platelets transfusion and FFPs transfusion were associated with HAI, but there was no dose-response relationship between them.

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A cross-sectional analysis of respiratory ill-health among charcoal workers and its implications for strengthening occupational health services in southern Nigeria

BMJ Open ◽

10.1136/bmjopen-2018-022361 ◽

2019 ◽

Vol 9 (1) ◽

pp. e022361 ◽

Cited By ~ 2

Author(s):

Irikefe Paul Obiebi ◽

Patrick Gold Oyibo

Keyword(s):

Dose Response ◽

Air Pollutants ◽

Respiratory Symptoms ◽

Secondary Outcome ◽

Response Relationship ◽

Chest Tightness ◽

Dose Response Relationship ◽

Cross Sectional ◽

Hazard Control ◽

Exposure Levels

ObjectivesThis study was conducted to assess the concentration of air pollutants at charcoal sites, the dose-response relationship between site-based exposure levels to air pollutants and prevalence of respiratory symptoms among charcoal workers, and the measures these workers employ to safeguard their health.DesignCross-sectional but comparative designSettingCharcoal production kiln sites in Sapele, Delta State, Nigeria.ParticipantsOverall 296 charcoal workers and age-matched, sex-matched and height-matched non-exposed traders (comparison group).Primary and secondary outcome measuresThe primary outcome measure was the prevalence of respiratory symptoms among charcoal workers while secondary outcomes included lung function indices as well as hazard control practices among charcoal workers.ResultsMajority (83.3%) of the sites had PM10and PM2.5values five times higher than the WHO standard. Charcoal workers were more likely to have respiratory symptoms; wheeze was statistically significant after adjusting for confounders, (OR 4.22; CI 1.37 to 12.99). The dose-response relationship between site-based exposure levels to air pollutants and the prevalence of respiratory symptoms among charcoal workers was statistically significant for all symptoms except chest tightness (p=0.167). Mean forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC) were considerably lower among workers with differences of −0.22 (−0.42 to −0.05) L and −0.52 (-0.76 to −0.29) L, respectively, whereas FEV1/FVC ratio and peak expiratory flow rate were higher among workers with mean differences of 5.68 (3.59–8.82)% and 0.31 (-23.70 to 24.43) L/min, respectively; but the mean difference was significant only for the FEV1/FVC ratio. Charcoal workers had poor hazard control practices; only 3.4% reportedly used personal protective equipment.ConclusionAir pollutants at kiln sites were higher than WHO standards. Despite the significantly higher prevalence of wheeze, chest tightness and chronic cough among charcoal workers, their hazard control practices were inadequate. Charcoal workers should adopt appropriate hazard control practices, and use improved devices which emit minimal pollutants.

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