scholarly journals Salvia hispanica L. (chia) seeds oil extracts reduce lipid accumulation and produce stress resistance in Caenorhabditis elegans

2018 ◽  
Vol 15 (1) ◽  
Author(s):  
Cristiane Freitas Rodrigues ◽  
Willian Salgueiro ◽  
Matheus Bianchini ◽  
Juliana Cristina Veit ◽  
Robson Luiz Puntel ◽  
...  
2021 ◽  
pp. 1-17
Author(s):  
Mani Iyer Prasanth ◽  
James Michael Brimson ◽  
Dicson Sheeja Malar ◽  
Anchalee Prasansuklab ◽  
Tewin Tencomnao

BACKGROUND: Streblus asper Lour., has been reported to have anti-aging and neuroprotective efficacies in vitro. OBJECTIVE: To analyze the anti-aging, anti-photoaging and neuroprotective efficacies of S. asper in Caenorhabditis elegans. METHODS: C. elegans (wild type and gene specific mutants) were treated with S. asper extract and analyzed for lifespan and other health benefits through physiological assays, fluorescence microscopy, qPCR and Western blot. RESULTS: The plant extract was found to increase the lifespan, reduce the accumulation of lipofuscin and modulate the expression of candidate genes. It could extend the lifespan of both daf-16 and daf-2 mutants whereas the pmk-1 mutant showed no effect. The activation of skn-1 was observed in skn-1::GFP transgenic strain and in qPCR expression. Further, the extract can extend the lifespan of UV-A exposed nematodes along with reducing ROS levels. Additionally, the extract also extends lifespan and reduces paralysis in Aβ transgenic strain, apart from reducing Aβ expression. CONCLUSIONS: S. asper was able to extend the lifespan and healthspan of C. elegans which was independent of DAF-16 pathway but dependent on SKN-1 and MAPK which could play a vital role in eliciting the anti-aging, anti-photoaging and neuroprotective effects, as the extract could impart oxidative stress resistance and neuroprotection.


Agronomy ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2012
Author(s):  
Samantha Jo Grimes ◽  
Filippo Capezzone ◽  
Peteh Mehdi Nkebiwe ◽  
Simone Graeff-Hönninger

Rising consumer attraction towards superfoods and the steadily increasing demand for healthy, environmentally sustainable, and regionally produced food products has sharpened the demand for chia. Over the course of 4 years, two early flowering chia varieties belonging to Salvia hispanica L., and Salvia columbariae Benth. Species were identified to complete their phenological development and, therefore, able to reach maturity under a photoperiod >12 h, thus enabling the cultivation of chia in central Europe—more specifically, in southwestern Germany—consistently for the first time. Results obtained by the conducted field trial in 2018 showed that chia seed yields and thousand-seed mass ranged from 284.13 to 643.99 kg ha−1 and 0.92 to 1.36 g, respectively. Further, the statistical analyses showed that the protein content of the cultivated chia varieties ranged from 22.14 to 27.78%, the mucilage content varied from 10.35 to 20.66%, and the crude oil content amounted up to 28.00 and 31.73%. Fatty acid profiles were similar to previously reported data with α-Linolenic acid being the most prominent one, ranging from 60.40 to 65.87%, and we obtained ω6:ω3 ratios between 0.2 and 0.3. In conclusion, chia could represent a promising raw material from a nutritional point of view, while being able to diversify the local food basis of southwestern Germany.


2021 ◽  
Vol 28 ◽  
pp. 100187
Author(s):  
Ana Karoline Ferreira Ignácio Câmara ◽  
Maristela Midori Ozaki ◽  
Mirian Santos ◽  
Vitor André Silva Vidal ◽  
Wanessa Oliveira Ribeiro ◽  
...  

Author(s):  
Yufei Xue ◽  
Lejing Li ◽  
Xuemei Liu ◽  
Huanhuan Jiang ◽  
Yanping Zhao ◽  
...  

2021 ◽  
Vol 12 (7) ◽  
pp. 3069-3082
Author(s):  
Marcella Duarte Villas Mishima ◽  
Luiz Carlos Maia Ladeira ◽  
Bárbara Pereira da Silva ◽  
Renata Celi Lopes Toledo ◽  
Thomás Valente de Oliveira ◽  
...  

The combination of ovariectomy with high fat diet consumption, in this study, affected biometric parameters, oxidative stress, mineral content and ATPase pump activity, while chia consumption had positive effects on these factors.


LWT ◽  
2018 ◽  
Vol 90 ◽  
pp. 283-289 ◽  
Author(s):  
Julliane Carvalho Barros ◽  
Paulo Eduardo Sichetti Munekata ◽  
Manoela Alves Pires ◽  
Isabela Rodrigues ◽  
Oussama Slaoui Andaloussi ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document