Plants, food and treatments used by BaKongo tribes in Uíge (northern Angola) to affect the quality and quantity of human breast milk

Abstract Background Angola has one of the highest annual under-five mortality rates in in the world and malnutrition poses a severe problem in the country. This study is the first to focus on the traditional knowledge of plants, foods, and treatments used by the local population in the province of Uíge to affect the quality and quantity of human breast milk, since decades of independence and civil war impeded ethnobotanical studies in this area. Methods This study was conducted in eight municipalities in the province of Uíge, Northern Angola in February and March 2018. In 265 semi-structured interviews, 360 informants in 40 rural villages were asked about plants, food, and treatments used to affect the quality and quantity of human breast milk. Additionally, information on child mortality and the duration of breastfeeding were collected. Whenever possible, plant specimens were collected for later identification. To determine the local importance of the collected plants, food, and treatments, the Relative Frequency of Citations was calculated. Results Most women reported to have no problems with their breast milk production. The duration of breastfeeding meets the recommendations of the World Health Organization (WHO). Across all use categories, 69 plants from 36 plant families, and 21 other foods and treatments could be identified. Conclusions The study shows an overview of a variety of plants, foods, and treatments used by mothers as galactagogues, to “clean” or to reduce their breast milk and those which they avoided to use during the lactation period. There is great potential for further research into this traditional knowledge. Also, further analysis of some of the plants could be of interest.

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Oxidant and antioxidant status of human breast milk during lactation period

Dairy Science and Technology ◽

10.1007/s13594-015-0211-z ◽

2015 ◽

Vol 95 (3) ◽

pp. 295-302 ◽

Cited By ~ 19

Author(s):

Sevda Yuksel ◽

Ayse Arzu Yigit ◽

Miyase Cinar ◽

Nurgul Atmaca ◽

Yuksel Onaran

Keyword(s):

Breast Milk ◽

Antioxidant Status ◽

Human Breast Milk ◽

Lactation Period ◽

Human Breast

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Nuclear Magnetic Resonance Metabolomics Reveals Qualitative and Quantitative Differences in the Composition of Human Breast Milk and Milk Formulas

Nutrients ◽

10.3390/nu12040921 ◽

2020 ◽

Vol 12 (4) ◽

pp. 921

Author(s):

Dorota Garwolińska ◽

Weronika Hewelt-Belka ◽

Agata Kot-Wasik ◽

Ulrik Kræmer Sundekilde

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Breast Milk ◽

Free Form ◽

Resonance Spectroscopy ◽

Human Breast Milk ◽

Lactation Period ◽

Human Breast ◽

Qualitative And Quantitative ◽

Nuclear Magnetic

Commercial formula milk (FM) constitutes the best alternative to fulfill the nutritional requirements of infants when breastfeeding is precluded. Here, we present the comparative study of polar metabolite composition of human breast milk (HBM) and seven different brands of FM by nuclear magnetic resonance spectroscopy. The results of the multivariate data analysis exposed qualitative and quantitative differences between HBM and FM composition as well as within FM of various brands and in HBM itself (between individual mothers and lactation period). Several metabolites were found exclusively in HBM and FM. Statistically significant higher levels of isoleucine and methionine in their free form were detected in FM samples based on caprine milk, while FM samples based on bovine milk showed a higher level of glucose and galactose in comparison to HBM. The results suggest that the amelioration of FM formulation is imperative to better mimic the composition of minor nutrients in HBM.

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Comparison of the Characteristics of Breast Milk-derived Stem Cells with the Stem Cells Derived from the Other Sources: A Comparative Review

Current Stem Cell Research & Therapy ◽

10.2174/1574888x16666210622125309 ◽

2021 ◽

Vol 16 ◽

Author(s):

Ebrahim Rahmani-Moghadam ◽

Vahideh Zarrin ◽

Amir Mahmoodzadeh ◽

Marzieh Owrang ◽

Tahereh Talaei-Khozani

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Breast Milk ◽

Human Adipose Tissue ◽

Human Breast Milk ◽

Lactation Period ◽

Human Breast ◽

Differentiation Potential ◽

Comparative Review ◽

Promising Source

: Breast milk (BrM) not only supplies nutrition, but it also contains a diverse population of cells. It has been estimated that up to 6% of the cells in human milk possess the characteristics of mesenchymal stem cells (MSC). Available data also indicate that these cells are multipotent and capable of self-renewal and differentiation with other cells. In this review, we have compared different characteristics, such as CD markers, differentiation capacity, and morphology of stem cells, derived from human breast milk (hBr-MSC) with human bone marrow (hBMSC), Wharton's jelly (WJMSC), and human adipose tissue (hADMSC). Through the literature review, it was revealed that human breast milk-derived stem cells specifically express a group of cell surface markers, including CD14, CD31, CD45, and CD86. Importantly, a group of markers, CD13, CD29, CD44, CD105, CD106, CD146, and CD166, were identified, which were common in the four sources of stem cells. WJMSC, hBMSC, hADMSC, and hBr-MSC are potently able to differentiate into the mesoderm, ectoderm, and endoderm cell lineages. The ability of hBr-MSCs todifferentiate into the neural stem cells, neurons, adipocyte, hepatocyte, chondrocyte, osteocyte, and cardiomyocytes has made these cells a promising source of stem cells in regenerative medicine, while isolation of stem cells from the commonly used sources, such as bone marrow, requires invasive procedures. Although autologous breast milk-derived stem cells are an accessible source for women who are in the lactation period, breast milk can be considered as a source of stem cells with high differentiation potential without any ethical concern.

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Oxytocyn Massage Using Innovative Massage Tool and Conventional Effleurage Techniques to Increase Breastmilk Production in Post Partum Mothers

Childhood Stunting, Wasting, and Obesity, as the Critical Global Health Issues: Forging Cross-Sectoral Solutions ◽

10.26911/the7thicph.03.48 ◽

2020 ◽

Author(s):

Nining Istighosah ◽

◽

Aprilia Nurtika Sari ◽

Keyword(s):

Treatment Group ◽

Breast Milk ◽

Milk Production ◽

Exclusive Breastfeeding ◽

Post Partum ◽

World Health ◽

Breast Milk Production ◽

The World ◽

Massage Treatment ◽

Health Organization

ABSTRACT Background: Exclusive breastfeeding for the first six months of life is recommended by the World Health Organization and United Nations Children’s Fund. The World Health Organization (WHO) recommends exclusive breastfeeding for up to 6 months and continuous breastfeeding for up to 2 months. Exclusive breastfeeding is the most effective intervention to reduce infant mortality. It is estimated that it can prevent 13% of under-five mortality in low-income countries. This study aimed to analyze the difference in breastmilk volume before and after the mother received the oxytocin massage using innovative massage tool and conventional effleurage techniques. Subjects and Methods: This was a quasi-experiment study with a non-randomized control trial pretest-posttest design was conducted in Kediri from August to September 2020. The sample used was post-partum women on days 4 to 10 using purposive sampling technique. The dependent variable was amount of breast milk production. The independent variables were oxytocin massage treatment with effleurage technique, and the combination of oxytocin massage, effleurage technique and innovation massage tool. The data was analyzed by T-Test. Results: In the oxytocin massage treatment group used the conventional Effleurage method (Mean = 42; SD = 29) while in the massage treatment group using an innovative massage tool (Mean = 60; SD = 51) this was very different in the control group (Mean = 3.4; SD = 8.8) and it was statistically significant (p= 0.005). Conclusion: Giving oxytocin massage using an innovative massage device were higher than oxytocin massage using the conventional Effleurage method and massage using this innovative massage device had a statistical impact on increasing breast milk production Keywords: oxytocin massage, breast milk production, innovative massage tool Correspondence: Nining Istighosah. School of Midwifery Dharma Husada Kediri. Jl. Penanggungan No. 41-A Kediri. E-mail: [email protected]. Mobile: +6281231352032. DOI: https://doi.org/10.26911/the7thicph.03.48

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Association of sCD14 in human breast milk with child atopic dermatitis: Results of the Ulm Birth Cohort Study and the Ulm SPATZ Health Study

10.1055/s-0037-1605765 ◽

2017 ◽

Author(s):

CA Logan ◽

J Weiss ◽

W Koenig ◽

V Walter ◽

H Brenner ◽

...

Keyword(s):

Atopic Dermatitis ◽

Cohort Study ◽

Breast Milk ◽

Birth Cohort ◽

Health Study ◽

Birth Cohort Study ◽

Human Breast Milk ◽

Human Breast

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Molecular Properties of Egg Allergen in Human Breast Milk and Its Physiological Function

Nippon Shokuhin Kagaku Kogaku Kaishi ◽

10.3136/nskkk.61.450 ◽

2014 ◽

Vol 61 (9) ◽

pp. 450-454

Author(s):

Hiroshi Narita

Keyword(s):

Breast Milk ◽

Physiological Function ◽

Molecular Properties ◽

Human Breast Milk ◽

Human Breast

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Organohalogen compounds in human breast milk from Republic of Buryatia, Russia

Environmental Pollution ◽

10.1016/j.envpol.2006.04.036 ◽

2007 ◽

Vol 146 (1) ◽

pp. 225-232 ◽

Cited By ~ 85

Author(s):

Oyuna V. Tsydenova ◽

Agus Sudaryanto ◽

Natsuko Kajiwara ◽

Tatsuya Kunisue ◽

Valeriy B. Batoev ◽

...

Keyword(s):

Breast Milk ◽

Human Breast Milk ◽

Human Breast ◽

Organohalogen Compounds

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Human breast milk suppresses the transcriptional regulation of IL-1β-induced NF-κB signaling in human intestinal cells

AJP Cell Physiology ◽

10.1152/ajpcell.00471.2003 ◽

2004 ◽

Vol 287 (5) ◽

pp. C1404-C1411 ◽

Cited By ~ 40

Author(s):

Ryoko Minekawa ◽

Takashi Takeda ◽

Masahiro Sakata ◽

Masami Hayashi ◽

Aki Isobe ◽

...

Keyword(s):

Breast Milk ◽

Pathogenic Bacteria ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Nuclear Factor Κb ◽

Protective Role ◽

Intestinal Cells ◽

Human Breast Milk ◽

Human Breast ◽

Activation Pathway

Neonatal necrotizing enterocolitis (NEC), which is a disease with a poor prognosis, is considered to be caused by the coincidence of intestinal ischemia-reperfusion injury and systemic inflammation due to the colonization of pathogenic bacteria. Interleukin (IL)-8, a proinflammatory cytokine, plays an important role in the pathophysiology of NEC. It was recently reported that IL-1β activates the IL-8 gene by regulating the transcriptional nuclear factor κB (NF-κB) signaling pathways in intestinal cells. The protective role of maternal milk in NEC pathogenesis has been reported in both human and animal studies. In this study, we show that human breast milk dramatically suppressed the IL-1β-induced activation of the IL-8 gene promoter by inhibiting the activation pathway of NF-κB. Moreover, we also show that human breast milk induced the production of IκBα. These results suggest that human breast milk could be protective and therapeutic in neonates with NEC by inhibiting the activation pathway of NF-κB.

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Comparison of Vitamin D and 25-Hydroxyvitamin D Concentrations in Human Breast Milk between 1989 and 2016–2017

Nutrients ◽

10.3390/nu13020573 ◽

2021 ◽

Vol 13 (2) ◽

pp. 573

Author(s):

Naoko Tsugawa ◽

Mayu Nishino ◽

Akiko Kuwabara ◽

Honami Ogasawara ◽

Maya Kamao ◽

...

Keyword(s):

Vitamin D ◽

Breast Milk ◽

Sun Exposure ◽

Stepwise Multiple Regression ◽

Human Breast Milk ◽

Vitamin D Status ◽

Human Breast ◽

Hydroxyvitamin D ◽

Lactating Mothers ◽

25 Hydroxyvitamin D

Background: Breast milk is considered the optimal source of nutrition during infancy. Although the vitamin D concentration in human breast milk is generally considered poor for infants, vitamin D in breast milk is an important source for exclusively breastfed infants. Increases in vitamin D insufficiency and deficiency in lactating mothers may reduce vitamin D concentrations in breast milk. This study aimed to compare vitamin D and 25-hydroxyvitamin D (25OHD) concentrations in breast milk collected in 1989 and 2016–2017 and simultaneously analyze them with liquid chromatography-tandem mass spectrometry (LC-MS/MS); the association between the lifestyle of recent lactating mothers (2016–2017) and vitamin D status in human breast milk was also evaluated. Method: Lactating mothers were recruited from three regions of Japan in 1989 (n = 72) and 2016–2017 (n = 90), and milk from 3–4 months was collected in summer and winter. The samples were strictly sealed and stored at −80℃ until measurement. Breast milk vitamin D and 25OHD concentrations were analyzed by LC-MS/MS. Vitamin D intake, sun exposure, and sunscreen use of the lactating mothers in 2016–2017 were assessed. Results: Both vitamin D and 25OHD concentrations in breast milk were higher in the summer regardless of the survey year. Significantly lower vitamin D and 25OHD concentrations were observed in 2016–2017 compared with 1989 in summer, but no survey year difference was observed in winter. The stepwise multiple regression analyses identified season, daily outdoor activity, and suntan in the last 12 months as independent factors associated with vitamin D3 concentrations. Conclusion: The results suggest that low vitamin D status in recent lactating mothers may have decreased vitamin D and 25OHD concentrations in breast milk compared with the 1980s. These results are helpful for developing public health strategies to improve vitamin D status in lactating mothers and infants.

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