scholarly journals Neuromas at the castration site in geldings

2019 ◽  
Vol 61 (1) ◽  
Author(s):  
Emma Angelina Bengtsdotter ◽  
Stina Ekman ◽  
Pia Haubro Andersen
Keyword(s):  
Small Groups ◽  
Spermatic Cord ◽  
Hind Limb ◽  
Fibrous Tissue ◽  
Neural Tissue ◽  
Nerve Tissue ◽  
Clinical Consequence ◽  
Anatomical Location ◽  
Future Studies ◽  
The Individual

Abstract Background Inguinal pain, unexplained hind limb lameness, back pain or behavioural problems in geldings could be attributable to painful neuromas that develop as a consequence of crushing and severing the testicular nerves during castration. The presence of neuroma in this anatomical location has never been reported, hence the knowledge of possible clinical relevance is limited. The aim of this study was to histologically investigate the testicular nerves at the castration site in geldings for the presence of neuromas. Proximal spermatic cord remnants were collected from 20 geldings admitted to routine post mortem examination for various reasons. The time of castration was unknown, but it had not been performed during the last year. Spermatic cord specimens were immersed in 10% formalin, trimmed, dehydrated, embedded in paraffin, sectioned and stained with haematoxylin and eosin (HE) for light microscopy. Identification of nerve tissue was done by immuno-localization of nerve specific enolase (NSE). Results Neuromas were found in 21 spermatic cords from 13 geldings and were bilateral in eight of the horses. The neuromas consisted of areas with small groups of non-neoplastic proliferations of peripheral neural tissue. The tissue included neurofilaments and Schwann cells, intermingled or surrounded with, epineural, perineural and endoneural fibrous tissue. The neural tissue immunostained positive with NSE. Conclusions This study showed neuromas of the remnant testicular nerves at the site of castration. Further studies are required to establish if these neuromas in the castration site are painful and if certain castration methods promote their formation. Future studies should also investigate the clinical consequence of these neuromas for the individual horse.

Cystic Bone Lesions in Horses and Humans: A Comparative Review

1998 ◽  
Vol 11 (01) ◽  
pp. 08-18 ◽  
Author(s):  
C. W. McIlwraith ◽  
J. A. Auer ◽  
Brigitte von Rechenberg
Keyword(s):  
Recurrence Rate ◽  
Subchondral Bone ◽  
Fibrous Tissue ◽  
Clinical Signs ◽  
Bone Lesions ◽  
Anatomical Location ◽  
Cystic Lesions ◽  
Bone Cysts ◽  
Biological Behaviour ◽  
Comparative Review

SummaryCases of cystic bone lesions in horses and humans were reviewed in the literature. These lesions are radiolucent areas of bone, recognized as subchondral cystic lesions in the horse (SCL), intra-osseous ganglia (IOG), subchondral bone cysts secondary to osteoarthrosis (OAC), and unicameral bone cysts (UCB) in humans. Their morphology is quite similar, consisting of lesions with a distinct cyst wall, and a cavity filled with fibrous tissue and yellowish mucoid fluid. The lesions are surrounded by sclerotic bone and can be easily diagnosed radiographically. SCL, IOG and OAC occur in the subchondral bone close to the adjacent joint, whereas UCB occur in the metaphysis of long bones. Their aetiology and pathogenesis is still unknown, although primary damage to the subchondral bone, cartilage or local blood supply and growth disturbances are discussed. In this review 703 lesions of SCL in horses, 289 lesions of IOG and 1460 lesions of UCB in humans were compared in their anatomical location and clinical signs. SCL and OAC resembled each other with respect to anatomical location. A correlation of affected bones could not be found for all four groups. Clinical presentation concerning age was most similar for SCL and UCB with both lesions mainly occurring in young individuals. Gender predominance of males was present in SCL, IOG and UCB. Clinical diagnosis was either incidental, or connected with intermittent pain in all lesions except for OAC. Additionally, the lesions were also found in conjunction with degenerative joint disease (SCL, OAC) or pathological fractures (UCB). Cystic bone lesions were either treated conservatively, surgically with curettage alone, curettage in combination with grafting procedures, or intra-lesional application of corticosteroids. SCL and UCB were similar in their biological behaviour concerning their slow response to the therapy and relatively high recurrence rate. None of the cystic bone lesions were comparable, and a common aetiology and pathogenesis could not be found.In a literature review cases of cystic bone lesions in horses and humans were compared with the goal to find a common aetiology and pathogenesis. Cystic bone lesions occur in horses as subchondral cystic lesions (SCL), and in humans as either intra-osseous ganglia (IOG), subchondral cystic lesions secondary to osteoarthrosis (OAC) or unicameral bone cysts (UCB). IOG and OAC compare with SCL mainly in the anatomical location. IOG and SCL resemble each other in size, clinical signs and histology, whereas UCB and SCL show a similar biological behaviour regarding their therapeutic response and recurrence rate. None of the cystic bone lesions in humans were comparable to the SCL in horses in all aspects. A common aetiology and pathogenesis could not be established.

EVALUATION OF OCCURRENCE OF HYPERDONTIA IN NON-SYNDROMIC POPULATION FROM BIHAR REGION

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Minti Kumari ◽  
Dr. Madhuri Kumari ◽  
Dr Anurag Rai ◽  
Dr. Navin Kumar
Keyword(s):  
Panoramic Radiograph ◽  
Permanent Dentition ◽  
Dental Anomalies ◽  
Supernumerary Teeth ◽  
Panoramic Radiographs ◽  
Future Studies ◽  
Asian Populations ◽  
Males And Females ◽  
The Individual ◽  
Clinical Records

It is evident that hyperdontia is more common in the permanent dentition than in the primary. There is a considerable difference between males and females in the prevalence of these teeth in permanent dentition; hyperdontia is twice as common in males as in females. However, this approximation varies in terms of location, other associating syndromes that may be present, and the ethnicity of the individual. In terms of ethnicity, it can be seen that hyperdontia is in fact less common in Caucasian than in Asian populations. There is evidence to show that an individual is more likely to have hyperdontia if other members of their family also have the condition. Hence the present study was planned for evaluation of occurrence of hyperdontia in non-syndromic  population from Bihar Region. The present study was planned in Public Health Dentistry, Patna Dental College and Hospital, Patna, Bihar. Total 195 patients referred to Department of Dentistry were evaluated in the present study. Panoramic radiographs and clinical records of patients above the age of 18 years and without any syndromic features were selected for the study.  All the radiographs were examined for the presence of supernumerary teeth, their location, morphology, and number. Morphologically, teeth were classified as conical, tuberculate, supplemental, and odontoma. Early diagnosis of dental anomalies can prevent some esthetic, orthodontic, and periodontal problems, and knowledge of the prevalence and distribution of the anomalies may help clinicians to the detection of these anomalies at early stages. Our study evaluated the prevalence of selected dental anomalies; future studies should investigate the prevalence of dental anomalies of all types. Keywords: Hyperdontia, non-syndromic, panoramic radiograph, supernumerary teeth, etc.

scholarly journals Examining the Effects of Three Group-Level Metacognitive Scaffoldings on In-Service Teachers’ Knowledge Building

2021 ◽  
pp. 073563312110308
Author(s):  
Fan Ouyang ◽  
Si Chen ◽  
Yuqin Yang ◽  
Yunqing Chen
Keyword(s):  
Small Groups ◽  
Mixed Method ◽  
Peer Interactions ◽  
Knowledge Building ◽  
Group Level ◽  
Question Asking ◽  
Individual Level ◽  
The Individual ◽  
Task Oriented ◽  
Metacognitive Scaffolding

Group-level metacognitive scaffolding is critical for productive knowledge building. However, previous research mainly focuses on the individual-level metacognitive scaffoldings in helping learners improve knowledge building, and little effort has been made to develop group-level metacognitive scaffolding (GMS) for knowledge building. This research designed three group-level metacognitive scaffoldings of general, task-oriented, and idea-oriented scaffoldings to facilitate in-service teachers’ knowledge building in small groups. A mixed method is used to examine the effects of the GMSs on groups’ knowledge building processes, performances, and perceptions. Results indicate a complication of the effects of GMSs on knowledge building. The idea-oriented scaffolding has potential to facilitate question-asking and perspective-proposing inquiry through peer interactions; the general scaffolding does not necessarily lessen teachers’ idea-centered explanation and elaboration on the individual level; the task-oriented scaffolding has the worst effect. Pedagogical and research implications are discussed to foster knowledge building with the support of GMSs.

scholarly journals Bile Acids Function Synergistically To Repress Invasion Gene Expression in Salmonella by Destabilizing the Invasion Regulator HilD

2016 ◽  
Vol 84 (8) ◽  
pp. 2198-2208 ◽  
Author(s):  
Colleen R. Eade ◽  
Chien-Che Hung ◽  
Brian Bullard ◽  
Geoffrey Gonzalez-Escobedo ◽  
John S. Gunn ◽  
...  
Keyword(s):  
Bile Acids ◽  
Type Iii Secretion ◽  
Acute Infection ◽  
Short Chain Fatty Acids ◽  
Common Mechanism ◽  
Environmental Cues ◽  
Anatomical Location ◽  
Content Type ◽  
Bacterial Signaling ◽  
The Individual

Salmonellaspp. are carried by and can acutely infect agricultural animals and humans. After ingestion, salmonellae traverse the upper digestive tract and initiate tissue invasion of the distal ileum, a virulence process carried out by the type III secretion system encoded withinSalmonellapathogenicity island 1 (SPI-1). Salmonellae coordinate SPI-1 expression with anatomical location via environmental cues, one of which is bile, a complex digestive fluid that causes potent repression of SPI-1 genes. The individual components of bile responsible for SPI-1 repression have not been previously characterized, nor have the bacterial signaling processes that modulate their effects been determined. Here, we characterize the mechanism by which bile represses SPI-1 expression. Individual bile acids exhibit repressive activity on SPI-1-regulated genes that requires neither passive diffusion nor OmpF-mediated entry. By using genetic methods, the effects of bile and bile acids were shown to require the invasion gene transcriptional activatorhilDand to function independently of known upstream signaling pathways. Protein analysis techniques showed that SPI-1 repression by bile acids is mediated by posttranslational destabilization of HilD. Finally, we found that bile acids function synergistically to achieve the overall repressive activity of bile. These studies demonstrate a common mechanism by which diverse environmental cues (e.g., certain short-chain fatty acids and bile acids) inhibit SPI-1 expression. These data provide information relevant toSalmonellapathogenesis during acute infection in the intestine and during chronic infection of the gallbladder and inform the basis for development of therapeutics to inhibit invasion as a means of repressingSalmonellapathogenicity.

Perceived Causal Problem Networks: Reliability, Central Problems, and Clinical Utility for Depression

Assessment ◽  
2021 ◽  
pp. 107319112110392
Author(s):  
Lars Klintwall ◽  
Martin Bellander ◽  
Matti Cervin
Keyword(s):  
Clinical Utility ◽  
Treatment Success ◽  
Centrality Measures ◽  
Retest Reliability ◽  
Causal Relations ◽  
Future Studies ◽  
Causal Networks ◽  
Novel Method ◽  
The Individual ◽  
Test Retest Reliability

Personalized case conceptualization is often regarded as a prerequisite for treatment success in psychotherapy for patients with comorbidity. This article presents Perceived Causal Networks, a novel method in which patients rate perceived causal relations among behavioral and emotional problems. First, 231 respondents screening positive for depression completed an online Perceived Causal Networks questionnaire. Median completion time (including repeat items to assess immediate test–retest reliability) was 22.7 minutes, and centrality measures showed excellent immediate test–retest reliability. Networks were highly idiosyncratic, but worrying and ruminating were the most central items for a third of respondents. Second, 50 psychotherapists rated the clinical utility of Perceived Causal Networks visualizations. Ninety-six percent rated the networks as clinically useful, and the information in the individual visualizations was judged to contain 47% of the information typically collected during a psychotherapy assessment phase. Future studies should individualize networks further and evaluate the validity of perceived causal relations.

Carbon nanotubes: a promise for nerve tissue engineering?

2013 ◽  
Vol 2 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Susanna Bosi ◽  
Alessandra Fabbro ◽  
Laura Ballerini ◽  
Maurizio Prato
Keyword(s):  
Carbon Nanotubes ◽  
Chemical Properties ◽  
Neural Tissue ◽  
Nerve Tissue ◽  
Physical And Chemical Properties ◽  
Electrically Conductive ◽  
Tissue Interface ◽  
Biomedical Field ◽  
Physical And Chemical ◽  
And Chemical Properties

AbstractOwing to their peculiar physical and chemical properties, carbon nanotubes are intensively studied for many different applications, including those in the biomedical field. Carbon nanotubes are electrically conductive, elastic but mechanically resistant and these features, among others, have made them an ideal material for therapeutic applications at the neural tissue interface. The major recent advances in the study of carbon nanotube-based materials aimed at nerve tissue regeneration and functional recovery are reviewed here.

scholarly journals Iatrogenic Inflammatory Fibrosis of Hard Palate in a 13-Year-Old Female Patient

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Shanthan Mettu ◽  
Radhika Muppa ◽  
G. Siva Prasad Reddy ◽  
Srinivas Nallanchakrava ◽  
Sri Veda Gurugubelli
Keyword(s):  
Female Patient ◽  
Hard Palate ◽  
Unusual Case ◽  
Fibrous Tissue ◽  
Surgical Excision ◽  
Inflammatory Cells ◽  
Nerve Tissue ◽  
Rare Occurrence ◽  
Reactive Process ◽  
Tooth Number

Palatal swellings are rare in children and the incidence differs from that of the adult counterparts. When the palatal swellings do arise in children, they usually are palatal abscess from periapical region, and few cases like pleomorphic adenoma in young adults have also been reported. But inflammatory fibrosis of palate in children is a rare occurrence. Inflammatory fibrosis is formation of excess fibrous connective tissue in an organ or tissue, as a reparative or reactive process. This report describes an unusual case of iatrogenic inflammatory fibrosis on the palate due to extraction of tooth number 22 in a 13-year-old female patient. The patient presented with a single large well-circumscribed oval palatal swelling that was soft, fluctuant, not fixed, and nontender. Surgical excision of the lesion was done and it was sent for histopathological assessment. The biopsy showed fibrous tissue with collagen fibers, spindle shaped fibroblasts, neovascularization, RBCs, chronic inflammatory cells, and traces of salivary gland and nerve tissue.

scholarly journals Risk ratios for contagious outcomes

2018 ◽  
Vol 15 (138) ◽  
pp. 20170696 ◽  
Author(s):  
Olga Morozova ◽  
Ted Cohen ◽  
Forrest W. Crawford
Keyword(s):  
Small Groups ◽  
Risk Ratio ◽  
Disease Transmission ◽  
Infectious Disease Transmission ◽  
Individual Level ◽  
Susceptibility To Infection ◽  
Definition Of ◽  
The Individual ◽  
The Relationship ◽  
Risk Ratios

Epidemiologists commonly use the risk ratio to summarize the relationship between a binary covariate and outcome, even when outcomes may be dependent. Investigations of transmissible diseases in clusters—households, villages or small groups—often report risk ratios. Epidemiologists have warned that risk ratios may be misleading when outcomes are contagious, but the nature of this error is poorly understood. In this study, we assess the meaning of the risk ratio when outcomes are contagious. We provide a mathematical definition of infectious disease transmission within clusters, based on the canonical stochastic susceptible–infective model. From this characterization, we define the individual-level ratio of instantaneous infection risks as the inferential target, and evaluate the properties of the risk ratio as an approximation of this quantity. We exhibit analytically and by simulation the circumstances under which the risk ratio implies an effect whose direction is opposite that of the true effect of the covariate. In particular, the risk ratio can be greater than one even when the covariate reduces both individual-level susceptibility to infection, and transmissibility once infected. We explain these findings in the epidemiologic language of confounding and Simpson's paradox, underscoring the pitfalls of failing to account for transmission when outcomes are contagious.

scholarly journals Binicilik Antrenörü Gözünde Hippoterapi

2020 ◽  
Vol 8 (10) ◽  
pp. 2131-2138
Author(s):  
Ali Ekber Ün
Keyword(s):  
Review Article ◽  
Public Institutions ◽  
Team Work ◽  
Individuals With Disabilities ◽  
Future Studies ◽  
Current Review ◽  
History Of ◽  
Expert Team ◽  
The Individual ◽  
Shed Light

The purpose of this review article is to collaborate on future studies about hippotherapy to horse and riding trainers, health professionals, veterinarians, individuals in need and individuals with disabilities and their relatives and to shed light on academic studies. It has been stated in studies that hippotherapy is beneficial for patients in the world. Therefore, as a result of new private hippotherapy centers in public institutions and in Turkey, studies on hippotherapy have been started. The studies carried out in hippotherapy are increasing and widespread and continuing to contribute to the treatment of the individuals in need and individuals with disabilities with hippotherapy sessions with expert teams. However, in the studies, the sessions of the hippotherapy team with two common creatures have great duties on the equestrian coaches in order to meet the needs of the horse and the individual in need or individual with disability. For this reason, since hippotherapy is a multidisciplinary team work consisting of specialist professionals, it has been researched to contribute to the horse and rider coaches on the field and to the expert team attending the sessions, to the new experts and the families of the individuals in need and disabled individuals. In the current review, the information about the history of hippotherapy and development, information about hippotherapy institutions in Turkey, individuals in need and individuals with disabilities, benefits of hippotherapy, characteristics of the hippotherapy horse, training of the hippotherapy horse are emphasized, and especially emphasis is placed on the use of work in the field of horse and equestrian coaching.

On the (Virtual) Road

2017 ◽  
pp. 164-179
Author(s):  
Robert Matthew Poole
Keyword(s):  
Virtual Reality ◽  
Travel Writing ◽  
Small Groups ◽  
Human Condition ◽  
Jack Kerouac ◽  
Social Commentary ◽  
Self Help ◽  
The Us ◽  
Individual Contributions ◽  
The Individual

In the US, travel writing and the travel novel have historically held important positions in the literary landscape –not only as self-help guides and conveyances for empirical information but also as vehicles for satire, social commentary and analyses of the human condition. John Steinbeck, Jack Kerouac and William Least Heat-Moon are just a few of the important 20th century authors who have made insightful use of this genre. Today, increasingly realistic virtual reality environments have been sculpted, imbued with creative content and populated with both artificial agents and real avatars on a scale that can be measured in hundreds of virtual square miles. In some cases, the content is thematic and designed; in others it has grown up spontaneously through the individual contributions and creativity of users and small groups. It is this spontaneous blossoming of art, culture and ideas sprawling across increasingly spacious and interconnected virtual landscapes that presents us with the opportunity to continue the tradition of the epic travel story across new virtual territory.

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