scholarly journals An 8-year-old-girl with juvenile dermatomyositis and autoimmune thyroiditis in Tanzania: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Fatima Mussa ◽  
Neema Nalitolela ◽  
Francis Fredrick

Abstract Background Juvenile dermatomyositis is an inflammatory disease of muscles, skin, and blood vessels of unknown cause affecting all age and ethnic groups, with a reported incidence of 1.9–4.1 per million. It manifests with weakness in axial and proximal muscles and typical skin lesions. Historically, the Bohan and Peter classification schema has been used to diagnose juvenile dermatomyositis. Case presentation We report an 8-year-old African female child, who presented with features of juvenile dermatomyositis and a rare association with subclinical autoimmune thyroiditis. This case illustrates the typical presentation, diagnosis, and treatment outcomes of this highly misdiagnosed condition. Conclusion Due to the limited resources and knowledge about this under-reported disease in resource-constrained settings, the characteristic manifestations of juvenile dermatomyositis can be easily missed and thus requires a high index of suspicion for earlier diagnosis and management.

2016 ◽  
Vol 27 (2) ◽  
pp. 46-48
Author(s):  
Md Mostafizur Rahman ◽  
Bilkis Ferdous ◽  
Sabbir Ahmed Tarik ◽  
Mohammad Mofiz Uddin ◽  
Akramul Haque

Juvenile dermatomyositis (JDM) is an autoimmune vasculopathy affecting children and adolescent under the age of 18 years. In this report, we describe a 9 years old boy who had myopathy and typical skin rash. Upon treatment with oral prednisolone and topical corticosteroid the patient condition considerably improved. Our case report illustrates that JDM requires comprehensive evaluation and multidisciplinary management.Medicine Today 2015 Vol.27(2): 46-48


Hand Surgery ◽  
2014 ◽  
Vol 19 (01) ◽  
pp. 131-133 ◽  
Author(s):  
Cenk Melikoglu ◽  
Fikret Eren ◽  
Barış Keklik ◽  
Cem Aslan ◽  
Mustafa Sutcu ◽  
...  

Introduction: Trichilemmal cysts (TCs) are common skin lesions that occur in hairy areas. A TC involving a fingertip has not been previously described in the literature. We herein report a case of a TC occupying a fingertip region. Case presentation: A 43-year-old woman presented with a 1.5 × 1.5 cm nodular lesion on the third fingertip. The lesion was completely excised, and histopathological examination revealed a TC. Conclusion: TCs may involve atypical locations, such as fingertips, where there are no hair follicles. After surgical excision, a careful histopathological examination should be performed to differentiate TCs from proliferating pilar tumors.


2021 ◽  
Author(s):  
Binrong Ye ◽  
Minyuan Xu ◽  
Yeqiang Liu

Abstract Background: Erythema elevatum diutinum (EED) is a rare disease that is associated with streptococcal infection, blood disorders, and autoimmunity. It is a chronic inflammatory dermatosis in the spectrum of cutaneous leukocytoclastic vasculitis. Typical skin lesions include nodules, erythema, and plaques; however, the presence of blister lesions is rare, especially on the limbs. Case presentation: We report a rare case of EED that presented as blisters on both limbs and the trunk of a 62-year-old woman. She responded well to oral corticosteroid and hydroxychloroquine treatment. The lesions were significantly improved after 2 weeks of treatment. Conclusions: EED is a rare form of cutaneous vasculitis. It is a good mimic of other types of skin diseases because of its diverse clinical presentations. It can even rarely present as blisters.


Author(s):  
Zeebaish S. ◽  
Hemalatha P. ◽  
Anusha Y. ◽  
Surendra Reddy N. ◽  
Durga Prasad T. S.

Tuberous sclerosis is a genetic multisystem disorder characterized by widespread hamartomas in several organs, including the brain, heart, skin, eyes, kidney, lung and liver.  The affected genes are TSC1 and TSC2, encoding hamartin and tuberin respectively.  Most features of tuberous sclerosis become evident only in childhood, limiting their usefulness for early diagnosis. We report a case of 3months old female child with seizures and hypo-pigmented skin lesions. The case is rare as it is documented in a family affected continuously in three generations involving four members.


2021 ◽  
Vol 9 (3) ◽  
pp. 263-268
Author(s):  
Hamed Jafarpour ◽  
◽  
Mahdie Sadat Mousavi ◽  
Shirin Sheibani ◽  
Javad Ghaffari ◽  
...  

Introduction: Acute Generalized Exanthematous Pustulosis (AGEP) is a cutaneous reaction that may appear after using certain medications, such as cephalexin. This disease is characterized by non-follicular sterile pustules, erythematous, urticaria, fever over , and leukocytosis. Cephalexin belongs to the family of β-lactam antibiotics, which are widely used to treat infections. However, cephalexin skin sensitivities have been reported rarely. Herein, in this case, we aimed to report a patient presented with AGEP due to cephalexin usage. Case Presentation: A 12-year-old boy presented with warm skin lesions that gradually appeared on the limbs, trunk, face, and neck after using cephalexin powder on his left leg injury. Because of his symptoms, acetaminophen, fexofenadine hydrochloride, loxoprofen sodium, and ointment, including difluprednate and hydrocortisone, were prescribed. Over time, the patient’s fever subsided, and 8 days later, the symptoms of AGEP, including urticaria, erythematous, and pustules in the neck and trunk, disappeared. Conclusions: Cephalexin is one of the antibiotics that doctors and patients consider when there is a possibility of infection. AGEP is a rare but severe reaction that can manifest as skin rashes in any age and sex following the use of cephalexin, so the patient should be careful when using this antibiotic.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Anka Sharma ◽  
Vikrant O. Kasat ◽  
Amit R. Parate ◽  
Anirudh Upmanyu ◽  
Jaishri S. Pagare

Abstract Background Parafunctional oral habits are known to cause deleterious effects on maxillofacial structures. One such effect is traumatic injuries secondary to chewing inanimate objects like pencils. Following trauma, the lead of the pencil has been reported to embed in the soft tissue of the oral cavity, appearing as a grayish pigmentation (graphite tattoo). However, such pigmentation has never been reported in the hard tissue (teeth). Case presentation We hereby report an interesting, first of its kind case in a four-year-old female child. She had been misdiagnosed and referred for the management of a carious tooth; which was, in reality, an exogenous deposit. Conclusions The authors highlight the impact of comprehensive history taking on arriving at the diagnosis. Counselling of the child and the parents goes a long way in flouting such deleterious habits.


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
L. Attar ◽  
N. Trabulsi ◽  
A. A. Maghrabi ◽  
M. Nassif

Introduction. Abdominal wall invasion by cancerous cells arising from the colon with an overlying secondary infection that presents as an abdominal wall abscess has been encountered previously, but such a symptom is rarely the first presentation of colon cancer. There are very few cases reported in the literature. Case Presentation. In this case report, we present a case of a 66-year-old male presenting with abdominal wall abscess that was refractory to treatment. The patient later was found to have an abdominal wall invasion by an underlying colonic carcinoma. Conclusion. The purpose of this review is to set forth the proper approach when encountering such cases and emphasize on the significance of keeping a high index of suspicion. We also highlight the need for utilizing proper diagnostic imaging modalities prior to invasive intervention.


2020 ◽  
Author(s):  
Huachao Guo ◽  
Zhen Ma ◽  
Shuo Wen ◽  
Yong Wang ◽  
Jiaguang Wang ◽  
...  

Abstract Background: ntraparenchymal meningiomas without dural attachment are extremely rare, especially in female children. To our knowledge, fibrous intraparenchymal meningioma located in the temporal lobe has never been reported in female children. The significance in the differential diagnosis of lesions in the temporal lobe should be emphasized.Case presentation: A 12-year-old girl was admitted to our hospital, complaining of recurrent generalized seizures for 2 months. Magnetic resonance imaging demonstrated a solid lesion located in the temporal lobe. The lesion underwent gross total resection. Histopathological examination indicated that the lesion was a fibrous meningioma. Postoperative rehabilitation was uneventful. Conclusions: This case report presents an extremely unusual intraparenchymal fibrous meningioma of the temporal lobe with peritumoral edema and reviewed 20 intraparenchymal meningioma cases in children and to discuss the clinical presentation and treatment, differential diagnosis, and radiological features.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Pragya Gautam Ghimire ◽  
Prasanna Ghimire ◽  
Jyoti Adhikari ◽  
Anurag Chapagain

Abstract Background Leishmaniasis and malaria are tropical diseases with more than half of the world population at risk of infection resulting in significant morbidity and mortality. Co-infection of Leishmaniasis and malaria pose a great challenge in the diagnosis as well as overall management. Case presentation In this case report, we present a rare case of a 5 years old child hailing from non-endemic region of Nepal with history of fever for a period of 3 months who was diagnosed as co-infection of malaria due to Plasmodium vivax and visceral Leishmaniasis with pancytopenia that subsequently improved after a course of treatment. Conclusions A high index of suspicion for a possibility of co-infection with Leishmaniasis and malaria should be borne in mind when an individual hailing from or having history of travel to endemic countries presents with prolonged fever.


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