scholarly journals A study on COVID-19 transmission dynamics: stability analysis of SEIR model with Hopf bifurcation for effect of time delay

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
M. Radha ◽  
S. Balamuralitharan

Abstract This paper deals with a general SEIR model for the coronavirus disease 2019 (COVID-19) with the effect of time delay proposed. We get the stability theorems for the disease-free equilibrium and provide adequate situations of the COVID-19 transmission dynamics equilibrium of present and absent cases. A Hopf bifurcation parameter τ concerns the effects of time delay and we demonstrate that the locally asymptotic stability holds for the present equilibrium. The reproduction number is brief in less than or greater than one, and it effectively is controlling the COVID-19 infection outbreak and subsequently reveals insight into understanding the patterns of the flare-up. We have included eight parameters and the least square method allows us to estimate the initial values for the Indian COVID-19 pandemic from real-life data. It is one of India’s current pandemic models that have been studied for the time being. This Covid19 SEIR model can apply with or without delay to all country’s current pandemic region, after estimating parameter values from their data. The sensitivity of seven parameters has also been explored. The paper also examines the impact of immune response time delay and the importance of determining essential parameters such as the transmission rate using sensitivity indices analysis. The numerical experiment is calculated to illustrate the theoretical results.

Author(s):  
M.Rasha ◽  
S.Balamuralitharan

Abstract This paper deals with a general SEIR model for the coronavirus disease 2019 (COVID-19) with the effect of time delay proposed. We get the stability theorems for disease-free equilibrium and provide adequate situations of the COVID-19 transmission dynamics equilibrium of present and absent cases. A Hopf bifurcation parameter $\tau$ is the effects of time delay and we demonstrate that the locally asymptotic stable is present equilibrium. The Reproduction number is brief in less than or greater than one, and it effectively controlling the COVID-19 infection outbreak, and subsequently reveals insight into understanding the patterns of the flare-up. The numerical experiment is calculated to help the theoretical outcomes.


Author(s):  
Vinod Baniya ◽  
Ram Keval

In the manuscript, the influence of time delay on the transmission of Japanese encephalitis model without vaccination model has been studied. The time delay is because of the existence of an incubation period during which the JE virus reproduces enough in the mosquitoes with the goal that it tends to be transmitted by the mosquitoes to people. The motivation behind this manuscript is to assess the influence of the time delay it takes to infect susceptible human populations after interacting with infected mosquitoes. The steady-states and the threshold value R0 of the delay model were resolved. This value assists with setting up the circumstance that ensure the asymptotic stability of relating  equilibrium points. Utilizing the delay as a bifurcation parameter, we built up the circumstance for the presence of a ”Hopf bifurcation”. Moreover, we infer an express equation to decide the stability and direction of ”Hopf bifurcation” at endemic equilibrium by using center manifold theory and normal structure strategy. It has been seen that delay plays a vital role in stability exchanging. In addition, larger values of virus transmission rate from an infected mosquito to  susceptible individuals and the natural mortality of humans of a model affect the existence of ”Hopf bifurcation”. Finally, to understand some analytical outcomes, the delay framework is simulated numerically.


Author(s):  
Bernd Brüggenjürgen ◽  
Hans-Peter Stricker ◽  
Lilian Krist ◽  
Miriam Ortiz ◽  
Thomas Reinhold ◽  
...  

Abstract Aim To use a Delphi-panel-based assessment of the effectiveness of different non-pharmaceutical interventions (NPI) in order to retrospectively approximate and to prospectively predict the SARS-CoV-2 pandemic progression via a SEIR model (susceptible, exposed, infectious, removed). Methods We applied an evidence-educated Delphi-panel approach to elicit the impact of NPIs on the SARS-CoV-2 transmission rate R0 in Germany. Effectiveness was defined as the product of efficacy and compliance. A discrete, deterministic SEIR model with time step of 1 day, a latency period of 1.8 days, duration of infectiousness of 5 days, and a share of the total population of 15% assumed to be protected by immunity was developed in order to estimate the impact of selected NPI measures on the course of the pandemic. The model was populated with the Delphi-panel results and varied in sensitivity analyses. Results Efficacy and compliance estimates for the three most effective NPIs were as follows: test and isolate 49% (efficacy)/78% (compliance), keeping distance 42%/74%, personal protection masks (cloth masks or other face masks) 33%/79%. Applying all NPI effectiveness estimates to the SEIR model resulted in a valid replication of reported occurrence of the German SARS-CoV-2 pandemic. A combination of four NPIs at consented compliance rates might curb the CoViD-19 pandemic. Conclusion Employing an evidence-educated Delphi-panel approach can support SARS-CoV-2 modelling. Future curbing scenarios require a combination of NPIs. A Delphi-panel-based NPI assessment and modelling might support public health policy decision making by informing sequence and number of needed public health measures.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wilfredo Angulo ◽  
José M. Ramírez ◽  
Dany De Cecchis ◽  
Juan Primera ◽  
Henry Pacheco ◽  
...  

AbstractCOVID-19 is a highly infectious disease that emerged in China at the end of 2019. The COVID-19 pandemic is the first known pandemic caused by a coronavirus, namely, the new and emerging SARS-CoV-2 coronavirus. In the present work, we present simulations of the initial outbreak of this new coronavirus using a modified transmission rate SEIR model that takes into account the impact of government actions and the perception of risk by individuals in reaction to the proportion of fatal cases. The parameters related to these effects were fitted to the number of infected cases in the 33 provinces of China. The data for Hubei Province, the probable site of origin of the current pandemic, were considered as a particular case for the simulation and showed that the theoretical model reproduces the behavior of the data, thus indicating the importance of combining government actions and individual risk perceptions when the proportion of fatal cases is greater than $$4\%$$ 4 % . The results show that the adjusted model reproduces the behavior of the data quite well for some provinces, suggesting that the spread of the disease differs when different actions are evaluated. The proposed model could help to predict outbreaks of viruses with a biological and molecular structure similar to that of SARS-CoV-2.


2018 ◽  
Vol 45 (11) ◽  
pp. 1550-1566
Author(s):  
Dharani Munusamy

Purpose The purpose of this paper is to examine the behavior of the stock market returns in the different days of the week and different months of the year in accordance with the Islamic calendar. Further, the study estimates the risk-adjusted returns to test the performance of the indices during the Ramadan and non-Ramadan days. Finally, the study investigates the impact of Ramadan on the returns and the volatility of the stock market indices in India. Design/methodology/approach Initially, the study applies the Ordinary Least Square method to test the day-of-the-week and the month-of-the-year effect of the common and Shariah indices. Next, the study employs the risk-adjusted measurement to examine the underperformance and over-performance of the indices for both the periods. Finally, the study estimates the GARCH (1,1) and GJR-GARCH (1,1) models to observe the impact of Ramadan on the returns and the volatility of the Shariah indices in India. Findings The study finds that an average return of the indices during the Ramadan days are higher than non-Ramadan days. Further, the average returns of the Shariah indices are significantly higher on Wednesday than other days of the week. In addition, the highest and significant mean returns and mean risk-adjusted returns of the indices during the Ramadan days are observed. Finally, the study finds an evidence of the Ramadan effect on the returns and volatility of the indices in India. Originality/value The study observes evidence that the Ramadan effect influences the Shariah indices, but not the common indices in the stock market of the non-Muslim countries. It indicates that the Ramadan creates the positive mood and emotions in the investors buying and selling activities. The study suggests that investors can buy the shares before Ramadan period and sell them during the Ramadan days to get an abnormal return in the emerging markets.


2018 ◽  
Vol 12 (2) ◽  
pp. 151-161 ◽  
Author(s):  
Muhammad Tahir ◽  
SAF Hasnu ◽  
Mario Ruiz Estrada

Purpose Trade openness plays a significant role in the growth process of countries. The purpose of this paper is to examine the impact of macroeconomic determinants on the trade openness of countries. Design/methodology/approach The study focuses on the South Asian Association for Regional Cooperation (SAARC) member countries and the data used were from 1971 to 2011. Panel data econometrics techniques and two stages least square method (TSLS) are used to carry out empirical analysis and robustness testing. Findings The main finding of the paper is that macroeconomic determinants such as investment both in physical and human capital and per capita gross domestic product (GDP) positively affect trade openness. Further, the size of labour force and currency exchange rate has also impacted trade openness negatively and significantly. Practical implications It implies that efficient macroeconomic management matters for higher trade openness. The sampled developing countries are suggested to pay favourable attention to macroeconomic variables if they want to grow in the long run through outward-oriented policies. Originality/value This paper is an original contribution in the context of SAARC countries by focusing on the relationship between macroeconomic determinants and trade openness.


2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Wanjun Xia ◽  
Soumen Kundu ◽  
Sarit Maitra

A delayed ecoepidemic model with ratio-dependent transmission rate has been proposed in this paper. Effects of the time delay due to the gestation of the predator are the main focus of our work. Sufficient conditions for local stability and existence of a Hopf bifurcation of the model are derived by regarding the time delay as the bifurcation parameter. Furthermore, properties of the Hopf bifurcation are investigated by using the normal form theory and the center manifold theorem. Finally, numerical simulations are carried out in order to validate our obtained theoretical results.


2021 ◽  
Vol 2083 (3) ◽  
pp. 032043
Author(s):  
Mengshuang Fu

Abstract With the rapid economic development, the urban space environment is becoming more and more complex, various accidents and disasters occur frequently, and safety risks are increasing. The rescue tasks involved in the fire brigade are showing a trend of diversification and complexity. The fire rescue team always puts the people first and insists on serving the people wholeheartedly. It is the guardian of maintaining social stability in our country and safeguarding the health and safety of people’s lives and property and various disaster affairs. The society needs the participation in the fire rescue team. Aiming at the fire rescue problem, this paper uses the fire rescue call data onto 2016 to 2019 to predict the number of fire rescues / rescued calls based on the difference equation to improve the rescue efficiency of the fire brigade. Taking into account the impact on the domestic epidemiced in 2020 on people’s lives, the adjustment value was introduced to adjust part of the alarm data onto 2020 to ensure the accuracy and reliability of the data. Finally, the second-order difference equation is used to predict the alarm data onto 2021 through the least square method, which verifies the accuracy of the model.


2021 ◽  
Vol 2091 (1) ◽  
pp. 012005
Author(s):  
Yuhao Cong ◽  
Yong Zhang ◽  
Guang-Da Hu

Abstract This paper is concerned with a linear time-delay circuit and its feedback control. We use electronic components such as resistors and capacitors to realize a linear time-delay system. The time-delays are generated by operational amplifiers and single-chip microcomputers. Based on the actual data measured by the oscilloscope, the parameters of the system are estimated using the least square method. Then a comparison study between the waveform image measured by the oscilloscope and the numerical simulation obtained by MATLAB verifies the effectiveness of the parameters estimations of the circuit system. Furthermore, the circuit system is unstable with a large time-delay, a feedback controller is designed to stabilize the circuit system using the optimization method in the literature. Finally, the experimental results in the linear time-delay circuit show the effectiveness of the optimization method.


Author(s):  
Peng Shi ◽  
Yinqiao Dong ◽  
Huanchang Yan ◽  
Xiaoyang Li ◽  
Chenkai Zhao ◽  
...  

ABSTRACTOBJECTIVETo investigate the impact of temperature and absolute humidity on the coronavirus disease 2019 (COVID-19) outbreak.DESIGNEcological study.SETTING31 provincial-level regions in mainland China.MAIN OUTCOME MEASURESData on COVID-19 incidence and climate between Jan 20 and Feb 29, 2020.RESULTSThe number of new confirm COVID-19 cases in mainland China peaked on Feb 1, 2020. COVID-19 daily incidence were lowest at -10 °C and highest at 10 °C, while the maximum incidence was observed at the absolute humidity of approximately 7 g/m3. COVID-19 incidence changed with temperature as daily incidence decreased when the temperature rose. No significant association between COVID-19 incidence and absolute humidity was observed in distributed lag nonlinear models. Additionally, A modified susceptible-exposed-infectious-recovered (M-SEIR) model confirmed that transmission rate decreased with the increase of temperature, leading to further decrease of infection rate and outbreak scale.CONCLUSIONTemperature is an environmental driver of the COVID-19 outbreak in China. Lower and higher temperatures might be positive to decrease the COVID-19 incidence. M-SEIR models help to better evaluate environmental and social impacts on COVID-19.What is already known on this topicMany infectious diseases present an environmental pattern in their incidence.Environmental factors, such as climate and weather condition, could drive the space and time correlations of infectious diseases, including influenza.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be transmitted through aerosols, large droplets, or direct contact with secretions (or fomites) as influenza virus can.Little is known about environmental pattern in COVID-19 incidence.What this study addsThe significant association between COVID-19 daily incidence and temperature was confirmed, using 3 methods, based on the data on COVID-19 and weather from 31 provincial-level regions in mainland China.Environmental factors were considered on the basis of SEIR model, and a modified susceptible-exposed-infectious-recovered (M-SEIR) model was developed.Simulations of the COVID-19 outbreak in Wuhan presented similar effects of temperature on incidence as the incidence decrease with the increase of temperature.


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