scholarly journals A bibliometric analysis of human strongyloidiasis research (1968 to 2017)

Author(s):  
Waleed M. Sweileh

Abstract Background Strongyloidiasis is a neglected tropical disease (NTD). It is commonly associated with poverty and poor hygiene. Strongyloidiasis poses an unseen global public health problem. The aim of this study was to assess and analyze peer-reviewed literature on human strongyloidiasis to shed light on the evolution, volume, important topics, and key players in the field of human strongyloidiasis. Methods A validated bibliometric method was implemented using Scopus database for the study period from 1968 to 2017. The search strategy was developed based on keywords related to strongyloidiasis. Bibliometric indicators and visualization maps were presented. Results In total, 1947 documents were found. Retrieved documents received 32,382 citations, an average of approximately 16.6 per document, and an h-index of 76. The most frequently encountered keywords in the retrieved literature focused on hyperinfection, diagnosis, prevalence, and ivermectin. The USA led with 540 (27.7%) documents followed by Brazil (139; 7.1%) and Japan (137; 7.0%). When research output was standardized by income and population size, India ranked first (12.4 documents per GDP/capita) followed by the USA (9.1 documents per GDP/capita). The most active journal involved in publishing articles was the American Journal of Tropical Medicine and Hygiene (95; 4.8%). In terms of institutions, the University of Ryukyus (Japan) was the most active with 62 (3.2%) publications, followed by the University of Pennsylvania with 54 (2.8%) publications. Conclusion The volume, growth, and international research collaboration in human strongyloidiasis were inadequate given the long history of the disease, the large number of affected people, and the results obtained for other NTDs. Research in human strongyloidiasis needs to be strengthened and encouraged in endemic regions in Southeast Asia and Latin America. International research networking needs to be established to achieve the goals of Sustainable Development Goals in fighting and eradicating NTDs by 2030.

Diseases ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 44
Author(s):  
Ozioma Forstinus Nwabor ◽  
Pawarisa Terbtothakun ◽  
Supayang P. Voravuthikunchai ◽  
Sarunyou Chusri

Colistin is a last resort antibiotic medication for the treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae. In recent years, various mechanisms have been reported to mediate colistin resistance in K. pneumoniae. This study reports a bibliometric analysis of published articles retrieved from the Scopus database relating to colistin resistance in K. pneumoniae. The research trends in colistin resistance and mechanisms of resistance were considered. A total of 1819 research articles published between 1995 and 2019 were retrieved, and the results indicated that 50.19% of the documents were published within 2017–2019. The USA had the highest participation with 340 (14.31%) articles and 14087 (17.61%) citations. Classification based on the WHO global epidemiological regions showed that the European Region contributed 42% of the articles while the American Region contributed 21%. The result further indicated that 45 countries had published at least 10 documents with strong international collaborations amounting to 272 links and a total linkage strength of 735. A total of 2282 keywords were retrieved; however, 57 keywords had ≥15 occurrences with 764 links and a total linkage strength of 2388. Furthermore, mcr-1, colistin resistance, NDM, mgrB, ceftazidime-avibactam, MDR, combination therapy, and carbapenem-resistant Enterobacteriaceae were the trending keywords. Concerning funders, the USA National Institute of Health funded 9.1% of the total research articles, topping the list. The analysis indicated poor research output, collaboration, and funding from Africa and South-East Asia and demands for improvement in international research collaboration.


2021 ◽  
Vol 17 ◽  
Author(s):  
Tuoyo O Mene-Afejuku ◽  
Abayomi O Bamgboje ◽  
Modele O Ogunniyi ◽  
Ola Akinboboye ◽  
Uzoma N Ibebuogu

Background: Heart failure (HF) is a global public health problem which affects over 23 million people worldwide. The prevalence of HF is higher among seniors in the USA and other developed countries. Ventricular arrhythmias (VAs) account for 50% of deaths among patients with HF. We aim to elucidate on the factors associated with VAs among seniors with HF, as well as therapies that may improve outcomes. Methods: PubMed, Web of Science, Scopus, Cochrane Library databases, Science Direct, and Google Scholar were searched using specific key words. The reference lists of relevant articles were searched for additional studies related to HF and VAs among seniors as well as associated outcomes. Results: The prevalence of VAs increases with worsening HF. 24-hour Holter electrocardiogram may be useful in risk stratifying patients for device therapy if they do not meet the criterion of low ventricular ejection fraction. Implantable cardiac defibrillators (ICDs) are superior to anti-arrhythmic drugs in reducing mortality in patients with HF. Guideline directed medical therapy (GDMT) together with device therapy to reduce symptoms may be required. In general, the proportion of seniors on GDMT is low. A combination of ICDs and cardiac resynchronization therapy may improve outcomes in select patients. Conclusion: Seniors with HF and VAs have a high mortality even with the use device therapy and GDMT. The holistic effect of device therapy on outcomes among seniors with HF is equivocal. More studies focused on seniors with advanced HF as well as therapeutic options is therefore required.


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Xiujuan Chen ◽  
Zhiqiang Zhang ◽  
Jinjing Guo

PurposeThe purpose of this paper is to provide theoretical basis and data support for researchers to choose appropriate international partners, provide a basis for Chinese research funding agencies, such as National Natural Science Foundation of China (NSFC) to formulate international research collaboration (IRC) strategies and policies and provide recommendations for the improvement of the internationalization level of China's basic scientific research.Design/methodology/approachBased on existing research, this study took output of “Major International (Regional) Joint Research Project” (MIJRP) funded by NSFC and participated by Chinese scholars in the meantime as the analysis object, proposed hypotheses and constructed the indicators of IRC and research output (RO). In addition, the mathematical statistics was used to compare the RO of China's IRC and nonIRC, and the statistical analysis model was used to measure the influence on RO of collaboration country's research capacity, research collaboration between China and US, scope of international research collaboration and reprint author country.FindingsThe RO of China's IRC is higher than that of nonIRC; research capacity of collaboration country has no inevitable effect on the RO of China's IRC; the RO of China's IRC participated by Americans is higher than that without American scholars; expanding the scope of China's IRC to some degree can increase RO; the RO of China's IRC led by foreigners is higher than that led by Chinese. In particular, China–US IRC and foreign scholars acting as the reprint author are two major factors for the RO of China's IRC.Originality/valueMost of the traditional research on IRC are based on the co-author papers, and this study tried to analyze the characteristics and regularities on IRC from a new view of international collaboration projects, which can be a supplement to the traditional international collaboration research on co-author papers.


2021 ◽  
Vol 4 (3) ◽  
pp. 820
Author(s):  
Angga Wijaya Holman Fasa ◽  
Mahardhika Berliandaldo

The coronavirus respiratory syndrome (COVID-19) pandemic has become a global public health problem. One of the main efforts to overcome this problem is research and development of technology in the health sector. This condition requires the readiness of the State Civil Apparatus (ASN), especially researchers and engineers, to increase the capacity or competence through technology transfer mechanisms in research collaboration schemes, both at the national and international levels. This study aims to find out, understand and explain two things, the urgency of research collaboration in the context of transferring COVID-19 countermeasures technology and strategic efforts to build research collaboration. This study uses a qualitative method with a descriptive analytical approach. The results of the study shows two things, first, that research collaboration in the context of technology transfer is significantly urgent to be implemented in order to encourage researchers and engineers to gain new knowledge about technology in the health sector, and second, strategic efforts that can be implemented by collaborating with researchers and engineers of credible research institutions in the health sector, and have implemented an open science policy which will significantly assist the technology transfer process without being constrained by intellectual property issues.


2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Waleed M. Sweileh

Abstract Background Evidence showed that mental health literacy reduces stigma and promotes help-seeking intentions. This study provides a bibliometric analysis of global research activity on mental health literacy. A bibliometric method was applied using Scopus. The term “mental health literacy” was searched in the title, abstract, and author keywords for the study period from 1900 to 2019. Conventional bibliometric indicators and mapping were generated. Results The search query found 945 documents. The earliest documents were published in 1997. The retrieved documents received an average of 25.3 citations per document and an h-index of 67. Authors from 68 different countries participated in publishing the retrieved documents. Australia ranked first (n=354, 37.5%) followed distantly by the USA (n=172, 18.2%). In total, 362 different journals participated in publishing the retrieved documents. The Australian and New Zealand Journal of Psychiatry (n=43, 11.8%) ranked first followed by the BMC Psychiatry (n=40, 11.0%). Documents published in the BMC Psychiatry journal received the highest number (60.4) of citations per document. In total, 3906 authors participated in publishing the retrieved documents. The average number of authors per document was 4.1. Jorm, A.F ranked first (n=96, 10.2%). Data analysis indicated that the University of Melbourne (n=136, 14.1%) ranked first in the number of publications. Conclusions Literature on “mental health literacy” is growing rapidly mainly in high-income countries. Research collaboration between active countries and low- and middle-income countries is important since many developing countries lack expertise and the infrastructure for mental health literacy research.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 1087
Author(s):  
Reham Moniem Ali ◽  
Deema Faisal Al-Saleh ◽  
Khadeeja M N Ansari ◽  
Hala A. El-Wakeel ◽  
Mai Ibrahim Shukri

Purpose: The primary objective of this research paper was to explore the current state-of-the-art research on autism spectrum disorder from a designer's perspective. An increasing number of scholarly publications in this discipline have urged researcher interest in this topic; however, there is still a lack of quantitative analysis. Therefore, this paper aims to analyze global research output on autism spectrum disorder from a designer's perspective during 1992–2021. Methodology: A bibliometric method was employed to analyze the published literature from 1992–2021. 812 papers were downloaded from the Web of Science core collection for analysis focused on annual growth of literature, prolific authors, authorship pattern, productive organizations, countries, international collaboration, literature trends by keyword analysis, and identifying the funding agencies. Various bibliometrics and scientometrics software were used to analyze the data, namely Bibexcel, Biblioshiny, and VOS viewer. Results: There were 812 research papers published in 405 sources during 1992–2021. 2019 was noted as the most productive year (NP=101), and 2014 received the highest number of citations (TC=6634). Researchers preferred to publish as journal articles (NP=538; TC=24922). The University of Toronto, Canada, was identified as a productive institution with 42 publications and 5358 citations. The USA was the leading producing country with 433 publications, and most of the researchers publish their work in the journal "Scientific Reports" (NP=16). The word "autism" (NP=257) and "architecture" (NP=165) were the most frequently used keywords in autism research.


2018 ◽  
Vol 9 (4) ◽  
pp. 617-628 ◽  
Author(s):  
Waleed M Sweileh

AbstractStigma and discrimination are major barriers in the global fight against human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). The aim of this study was to create an analytical inventory of worldwide research output in AIDS-related stigma and discrimination. SciVerse Scopus was used for the study period from 1980 to 2017 to retrieve literature in AIDS-related stigma and discrimination. Results were presented as bibliometric tables and maps. In total, 2,509 documents were retrieved. Approximately 40% (n = 990) of the retrieved documents were published in the last 5 years (2013–2017). Retrieved documents received an average of 19.8 citations per article and had an average of 3.2 authors per article. The Hirsh index of the retrieved documents was 94. Most frequently encountered topics were mental health, adherence, adolescents, women, disclosure, and Africa. The USA contributed to 1,226 (48.9%) documents while the African region contributed to 531 (21.2%) documents. Research collaboration among most active countries was relatively low. Authors and institutions from the USA dominated this field. AIDS Care was the most active journal in publishing documents in this field with 307 (13.4%) documents while documents published in Social Medicine journal received the highest citations. Research in AIDS-related stigma and discrimination had witnessed a noticeable increase in the past decade, but the overall number of publications is considered insignificant relative to the size of the problem and the global number of infected people. There was a relative underpresentation of literature from African region despite the fact that more than two-thirds of HIV-infected people in the world are living in Africa.


2020 ◽  
Vol 21 ◽  
Author(s):  
Andressa Kelly Ferreira e Silva ◽  
Antonielly Campinho dos Reis ◽  
Emanuelly Elanny Andrade Pinheiroc ◽  
Jonas Nascimento de Sousa ◽  
Felipe Araújo de Alcântara Oliveira ◽  
...  

Background: Microbial resistance to antibiotics is a global public health problem, which requires urgent attention. Platonia insignis is a native species from the eastern Brazilian Amazon, used in the treatment of burns and wounds. Objectives: To evaluate the antimicrobial activity of the hydroalcoholic extract of P. insignis (PIHA), the ethyl acetate fraction (PIAE), and its subfraction containing a mixture of biflavonoids (BF). Moreover, the effect of these natural products on the antibiotic activity against S. aureus strains overexpressing efflux pump genes was also evaluated. Methods: Minimal inhibitory concentrations were determined against different species of microorganisms. To evaluate the modulatory effect on the Norfloxacin-resistance, the MIC of this antibiotic was determined in the absence and presence of the natural products at subinhibitory concentrations. Inhibition of the EtBr efflux assays were conducted in the absence or presence of the natural products. Results: PIHA showed a microbicidal effect against S. aureus and C. albicans, while PIAE was bacteriosctatic for S. aureus. PIAE and BF at subinhibitory concentrations were able to reduce the MIC of Norfloxacin acting as modulating agents. BF was able to inhibit the efflux of EtBr efflux in S. aureus strains overexpressing specific efflux pump genes. Conclusion: P. inignisis a source of efflux pump inhibitors, including volkensiflavone and morelloflavone which were able to potentiate the Norfloxacin activity by NorA inhibition, being also able to inhibit QacA/B, TetK and MsrA. Volkensiflavone and morelloflavone could be used as adjuvant in the antibiotic therapy of multidrug resistant S. aureus strains overexpressing efflux pumps.


2019 ◽  
Vol 19 (8) ◽  
pp. 567-578 ◽  
Author(s):  
Marcus Vinicius Nora de Souza ◽  
Thais Cristina Mendonça Nogueira

Nowadays, tuberculosis (TB) is an important global public health problem, being responsible for millions of TB-related deaths worldwide. Due to the increased number of cases and resistance of Mycobacterium tuberculosis to all drugs used for the treatment of this disease, we desperately need new drugs and strategies that could reduce treatment time with fewer side effects, reduced cost and highly active drugs against resistant strains and latent disease. Considering that, 4H-1,3-benzothiazin-4-one is a promising class of antimycobacterial agents in special against TB-resistant strains being the aim of this review the discussion of different aspects of this chemical class such as synthesis, mechanism of action, medicinal chemistry and combination with other drugs.


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