scholarly journals Severe methanol poisoning treated with a novel hemodialysis system: a case report, analysis, and review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alisa C. Illescas ◽  
Christos P. Argyropoulos ◽  
Sara A. Combs ◽  
Saeed K. Shaffi ◽  
Zhi Q. Xu ◽  
...  
Keyword(s):  
High Efficiency ◽  
Standard Of Care ◽  
Intermittent Hemodialysis ◽  
Alcohol Poisoning ◽  
Methanol Poisoning ◽  
Novel Device ◽  
System A ◽  
Toxic Alcohol ◽  
Report Analysis ◽  
Hemodialysis System

AbstractIn May and June 2020, an outbreak of methanol poisoning arose in the southwest United States linked to ingestion of contaminated hand sanitizer imported during the coronavirus disease 2019 pandemic, ultimately resulting in over a dozen hospitalizations and at least four deaths in New Mexico and Arizona. In this report, we describe one of these cases in which profound methanol intoxication was successfully treated with the Tablo® Hemodialysis System, the first reported case of toxic alcohol poisoning treated with this novel device. We carry out a formal regression analysis of the serial methanol levels obtained in this case to conservatively estimate that intermittent hemodialysis with Tablo achieved a clearance of methanol of 239 mL/min (95% confidence interval, 173–305 mL/min), a clearance that is well within the previously published standard of care. We conclude by reviewing both the treatment of toxic alcohol poisoning and the determinants of small molecule clearance with hemodialysis, emphasizing the importance of optimizing the dialytic treatment of intoxications with extended treatment times and the use of high-efficiency dialyzers.

EFFICACY OF A NOVEL DEVICE TO DETECT, ALERT AND RESOLVE NEONATAL APNEA - PILOT STUDY

2019 ◽  
Vol 9 (9) ◽  
pp. 608-613
Author(s):  
Dr. Swapna Lingaldinna,Dr. Himabindu Singh,Mona Sharma*
Keyword(s):  
Newborn Care ◽  
Standard Of Care ◽  
The Novel ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Care Community ◽  
Novel Device ◽  
Sick Newborn ◽  
Central Apneas ◽  
Neonatal Apnea

Objective: To measure the accuracy of a novel device in detecting Bradycardia andDesaturation (B&D) events and to determine its efficacy in resolving apneas innewborns with comparison to standard monitor (which only detects B&D eventsand alerts).Design: This was a prospective observational study.Setting: Sick Newborn Care Unit of a large tertiary referral hospital in Hyderabad,India.Methods: 31 newborns were provided with a novel device, which monitored oxygensaturation and pulse rate and alarmed when values dropped below a set thresholdwhich is referred as an event, henceforth. The novel device also provided footstimulation in response to above-mentioned events. When the monitor alarmed, anurse attended to the baby to confirm whether the baby was breathing and whetherthe event had been resolved by the device. If the event had not resolved, appropriateaction as per the standard-of-care was performed.Results: The novel device “ApneBootTM” positively detected B&D events 94.03% oftimes as compared to the standard reference monitor. 56 of 67 observed B&D eventswere visually confirmed to be apneas, indicating that 83.6% of B&D eventscoincided with apneas. Of the 56 apneic events, 50 were central apneas, of which 35were resolved by the novel device, making the device’s efficacy of apnea resolution70%.Conclusion: The results of the study indicate that this novel device “ApneBootTM”is very effective in detecting and alarming B&D events, which coincides with theapnea, and resolving it by providing foot stimulation.Keywords: Novel Device, Neonatal Apnea, Low Birth Weight, Body Temperature,Kangaroo Mother Care, Community Health,

scholarly journals COVID-19 and Alcohol Poisoning: A Fatal Competition

2021 ◽  
pp. 1-10
Author(s):  
Mohammad Heidari ◽  
Nasrin Sayfouri
Keyword(s):  
Side Effects ◽  
Alcohol Consumption ◽  
Mass Media ◽  
The Body ◽  
Ministry Of Health ◽  
Alcohol Poisoning ◽  
Methanol Poisoning ◽  
The Public

ABSTRACT In March 2020, concurrently with the outbreak of COVID-19 in Iran, the rate of alcohol poisoning was unexpectedly increased in the country. This study has attempted to make an overall description and analysis of this phenomenon by collecting credible data from the field, news, and reports published by the emergency centers and the Iranian Ministry of Health. The investigations showed that in May 20, 2020, more than 6150 people have been affected by methanol poisoning from whom 804 deaths have been reported. A major cause of the increased rate of alcohol poisoning in this period was actually the illusion that alcohol could eliminate the Coronaviruses having entered the body. It is of utmost importance that all mass media try to dismiss the cultural, religious, and political considerations and prepare convincing programs to openly discuss the side-effects of forged alcohol consumption with the public, especially with the youth. It must be clearly specified that “consuming alcohol cannot help prevent COVID-19.”

Emulators as a Tool for Control Digital System Software Debugging

2021 ◽  
Vol 27 (7) ◽  
pp. 339-349
Author(s):  
A. D. Ivannikov ◽  
Keyword(s):  
Graphical Model ◽  
High Efficiency ◽  
Direct Memory Access ◽  
Practical Method ◽  
Digital System ◽  
Digital Systems ◽  
System Software ◽  
System A ◽  
Software Modules ◽  
Operational Program

The simulation of control digital systems at the architecture level, that is, emulation of the instruction set, memory cells and internal programmable registers, as well as the interrupt system and direct memory access is considered. Emulators are used for debugging embedded digital system software and in the development of new custom processors. Requirements for emulators are formalized. It is shown that the main requirements are adequate simulation of digital systems at the architecture level, the presence of a set of convenient debugging modes, as well as high efficiency of emulators, that is, the minimum possible average number of instrumental computer instructions required to simulate one instruction of the target digital system. A classification of the debugging capabilities of emulators and possible ways of implementing debugging modes is given. The composition of the emulators is described. A graphical model of the structure of the emulator is proposed. The simulation process for each instruction is presented as a sequence of execution of smaller operations. If different instructions include the same operations, these operations can be performed by the same software modules. These modules can be included in all the corresponding blocks of the emulator that simulate the execution of instructions, or the emulator can include only one copy of each operational program module, and the module can be accessed while simulating the corresponding instruction. Determination of the structure of the emulator is formalized as an extreme task, the objective function of which is the minimum average time for simulating the execution of one instruction of the target digital system, and the limitation is the maximum allowable memory size of the instrumental computer occupied by the emulator. A practical method for determining the structure of the emulator is proposed.

Indications for Dialysis in Acute Kidney Injury

2020 ◽  
Author(s):  
Ankit Patel ◽  
Kenneth B Christopher
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
High Efficiency ◽  
Kidney Injury ◽  
Intermittent Hemodialysis ◽  
Continuous Venovenous Hemofiltration ◽  
Continuous Venovenous Hemodialysis ◽  
Low Efficiency ◽  
The Impact

Renal replacement therapy (RRT) can be used to support patient’s kidney function in cases of acute kidney injury (AKI). However, timing, modality, and dosing of RRT continue to remain in question. Recent studies have begun to provide data to help guide clinicians on when to initiate RRT, what form of RRT to use ranging from continuous venovenous hemofiltration (VVH) to intermittent hemodialysis, and the impact of high versus low-intensity dosing. Additionally, the risks associated with temporary vascular access with regard to thrombosis and infection, the impact of high efficiency and flux versus low efficiency and flux membranes, and options for anticoagulation in RRT for AKI are also discussed. This review contains 75 references.  Key words: acute kidney injury, chronic kidney disease, continuous venovenous hemofiltration, continuous venovenous hemodialysis, renal replacement therapy, venovenous hemofiltration, 

scholarly journals High-efficiency photocatalytic CO2 reduction in organic–aqueous system: a new insight into the role of water

RSC Advances ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 3798-3802 ◽  
Author(s):  
Jinliang Lin ◽  
Rongying Liao ◽  
Junli Xu
Keyword(s):  
High Efficiency ◽  
Co2 Reduction ◽  
Liquid System ◽  
Aqueous System ◽  
Binary Liquid System ◽  
Binary Liquid ◽  
System A ◽  
System P ◽  
Insight Into

A high efficiency photocatalytic conversion of CO2 into CO has been achieved by construction of a binary liquid system.

scholarly journals Cardiac arrest in special circumstances: toxic alcohol poisoning

Resuscitation ◽  
2019 ◽  
Vol 142 ◽  
pp. e109
Author(s):  
Gabriela Raluca Grigorasi ◽  
Mihaela Corlade ◽  
Tudor Ovidiu Popa ◽  
Anca Haisan ◽  
Paul Nedelea ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Alcohol Poisoning ◽  
Toxic Alcohol ◽  
Special Circumstances

scholarly journals Recent Advances in and New Perspectives on Crystalline Silicon Solar Cells with Carrier-Selective Passivation Contacts

Crystals ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 430 ◽  
Author(s):  
Cao Yu ◽  
Shengzhi Xu ◽  
Jianxi Yao ◽  
Shuwei Han
Keyword(s):  
Thin Films ◽  
Solar Cells ◽  
High Efficiency ◽  
Crystalline Silicon ◽  
Global Market ◽  
Crystalline Silicon Solar Cells ◽  
Novel Device ◽  
Si Solar Cells ◽  
Passivation Layers ◽  
Conversion Efficiencies

Crystalline silicon (c-Si) is the dominating photovoltaic technology today, with a global market share of about 90%. Therefore, it is crucial for further improving the performance of c-Si solar cells and reducing their cost. Since 2014, continuous breakthroughs have been achieved in the conversion efficiencies of c-Si solar cells, with a current record of 26.6%. The great efficiency boosts originate not only from the materials, including Si wafers, emitters, passivation layers, and other functional thin films, but also from novel device structures and an understanding of the physics of solar cells. Among these achievements, the carrier-selective passivation contacts are undoubtedly crucial. Current carrier-selective passivation contacts can be realized either by silicon-based thin films or by elemental and/or compound thin films with extreme work functions. The current research and development status, as well as the future trends of these passivation contact materials, structures, and corresponding high-efficiency c-Si solar cells will be summarized.

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